临床护理研究最新文献

{"title":"Matrix Metalloproteinase-2, Matrix Metalloproteinase-9, and Transforming Growth Factor Beta 1 Levels in Escherichia coli-Infected Rats with Acute Pyelonephritis","authors":"J. Ji, Zhao Bi, L. Tian, Limin Zhang, X. Fan, Jing Li, Song Li","doi":"10.26689/jcnr.v7i2.4762","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4762","url":null,"abstract":"Objective: To investigate the expression of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), and transforming growth factor beta 1 (TGF beta 1) in the kidney tissue of rats with pyelonephritis and their relationship with pyelonephritis by establishing a rat model of acute pyelonephritis. Methods: 80 male Wistar rats were randomly divided into a control group and an experimental group, with 40 rats each. The rats of the control group were injected with and saline and those of the experimental group were injected with 10 ?g/mL Escherichia coli (E. coli) and saline (1:100); the solutions for both groups were administered every 3 days for 7 days. The expressions of MMP-2, MMP-9 and TGF beta 1 in the kidney tissues of rats in each group were observed. Results: The expression of MMP-9 and TGF beta 1in the kidney tissue of rat acute pyelonephritis model rats was significantly higher than those of the control group (P < 0.01); the MMP-9 mRNA content in the kidney tissue of the experimental group was significantly higher than that of the control group (P < 0.05); the TGF beta 1 mRNA content in the renal tissue of the experimental group increased significantly compared to the  (P < 0.05); MMP-2, MMP-9 and TGF beta 1 began to express in the early stage of pyelonephritis until the complete formation of renal pelvic edema. The difference between groups was statistically significant (P < 0.01). Conclusion: MMP-9 and TGF beta 1 are important factors regulating renal tubular epithelial cell injury and inflammatory response.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42606295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Reposition of an Incarcerated Gravid Uterus by Instrument: A Case Report and Literature Review","authors":"Jing Wang, Jing-Ru Jiao, Lingfu Wang, Ling-Ling Gong, Hong-Li Wu, Zhong-Yi Liu, Su-min Jiang","doi":"10.26689/jcnr.v7i2.4743","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4743","url":null,"abstract":"Incarcerated gravid uterus is a rare obstetric condition that contributes to pregnancy-related adverse outcomes, especially if the uterus remains incarcerated and the condition goes undiagnosed until delivery. An effective diagnosis of this condition is benefited from pelvic examination combined with imaging methods and based on suspected symptoms. We present a case of ultrasound-assisted instrument reposition of an incarcerated gravid uterus at mid-gestation and discuss its clinical characteristics, diagnosis, imaging features, and treatment. We believe that once manual reduction fails, the use of instruments will undoubtedly be a better choice.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41442854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Clinical Study of Integrated Traditional Chinese and Western Medicine in the Treatment of Liver-Stomach Disharmony Functional Dyspepsia","authors":"Xiaoqiang Nan, Zhe Hu","doi":"10.26689/jcnr.v7i2.4732","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4732","url":null,"abstract":"Objective: To explore the clinical effect of integrated traditional Chinese and Western medicine in the treatment of liver-stomach disharmony functional dyspepsia. Methods: Sixty patients with functional dyspepsia of liver-stomach disharmony type admitted to our hospital from January to August 2022 were selected as research subjects and randomly divided into two groups, a study group and a control group, with 30 cases in each group. The main observations were stomachache or pain over bilateral flanks, emotionally depressed, belching, fullness and discomfort over the abdomen and flanks, acid regurgitation, loss of appetite, frequent sighing, noisy epigastric, and the treatment effect. Results: According to the classification of symptom severity on the traditional Chinese medicine (TCM) symptom score table, statistics were made on the corresponding severity of the main symptoms and secondary symptoms of the two groups of patients, and the data of the two groups were compared by Wilcoxon test. The results showed that there was no significant difference in the distribution of TCM symptoms between the two groups; the study group’s total effective rate of pain relief (recovery + markedly effective + effective) was 96.67%, and Fisher’s ?2 test indicated a significant difference in the total effective rate of pain relief between the two groups (P = 0.027 < 0.05). Conclusion: The use of integrated traditional Chinese and western medicine is clearly better than the simple application of western medicine. It is safe and has no side effects. It can be used as a treatment for patients with functional dyspepsia.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42126834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the Effect of Zhuang Medicine Aponeurotic System Triple Therapy on Lumbar Disc Herniation and Alpha-1 Acid Glycoprotein Level","authors":"Yun Zhang, Yuying Lan, Yingcai Wei","doi":"10.26689/jcnr.v7i2.4790","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4790","url":null,"abstract":" Objective: To analyze the application effect of Zhuang medicine aponeurotic system triple therapy in the treatment of lumbar disc herniation and its effect on the level of alpha-1 acid glycoprotein (alpha-1 AGP). Methods: 200 patients with lumbar disc herniation were selected and randomly divided into a treatment group and a control group, 100 cases in each group. The control group was given conventional acupuncture, and the treatment group was treated with manipulation + fire needling + cupping. The alpha-1-AGP levels before and after treatment, as well as the lumbar spine function and pain scores before and after treatment, and the adverse reactions occurred during treatment between the two groups were compared. Results: Before treatment, there was no significant difference in alpha-1 AGP levels, lumbar function, and pain scores between the two groups (P > 0.05). After treatment, the lumbar function scores of the two groups were significantly increased, with the treatment group having higher scores than the control group (P < 0.05); the incidence of adverse reactions in the treatment group was 2.00%, which was much lower than the control group (P > 0.05). Conclusion: Appropriate application of Zhuang medicine aponeurotic system triple therapy in the clinical treatment of lumbar disc herniation can promote the improvement of alpha-1 AGP index level, reduce the pain degree of patients, and improve their lumbar spine function. At the same time, Zhuang medicine also has significant advantages in terms of safety, while ensuring the efficacy and safety of the treatment.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42475389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Analysis of Diabetic Nephropathy Risk Factors and Correlation with Blood Pressure Control","authors":"Xing-xia Fan, Z. Li","doi":"10.26689/jcnr.v7i2.4798","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4798","url":null,"abstract":"Objective: To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control. Methods: A retrospective analysis of 80 patients with diabetic nephropathy (diabetic nephropathy group) and another 80 patients with diabetes (diabetic group) who were admitted to the Department of Nephrology and Endocrinology at our hospital from October 2021 to October 2022 was conducted. The general data of the two groups were compared, the influencing factors associated with the two groups were analyzed unilaterally, and unconditional dichotomous logistic regression was performed to analyze the influencing factors in patients with diabetic nephropathy. Results: There were no significant differences in high-density lipoprotein, systolic blood pressure, diastolic blood pressure, and creatinine between the two groups (P > 0.05); however, compared with the diabetic group, the DN group had significantly elevated glycated hemoglobin, low-density lipoprotein, 24-h urine protein, insulin resistance, and diabetes duration ? 10 years (P < 0.05). Conclusion: The clinical research on the correlation between the incidence of hypertension and the control of blood pressure in patients with diabetic nephropathy should be strengthened in order to formulate reasonable and feasible treatment plans.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49438171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of the Integrated Medical Care Model Combined with Psychological Intervention in Tuberculosis Patients with Lung Cancer","authors":"W. Yuan, Dandan Yang, Xinyi Ye, Zhangying Li, X. Luan, Min Zheng, Yanling Feng, Mi Zhang, Chuo Guo","doi":"10.26689/jcnr.v7i2.4734","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4734","url":null,"abstract":"Objective: To explore the clinical efficacy of the integrated medical care model combined with psychological intervention in pulmonary tuberculosis patients with lung cancer. Methods: From January to December 2022, 60 pulmonary tuberculosis patients with lung cancer admitted to our hospital were selected as the research subjects. Using the random number table method, the patients were divided into two groups, a control group and a study group, with 30 cases in each group. The chest computed tomography (CT) examination results, mental state assessment (including depression scale and anxiety scale) scores, incidence of adverse reactions, treatment effect, and length of hospital stay were compared between the two groups. Results: The treatment effect of the patients in the study group was better than that of the patients in the control group (P < 0.05); the duration of hospitalization, chest CT examination results, mental state assessment scores, and incidence of adverse reactions of the study group and the control group, were significantly different (P < 0.05). Conclusion: The integrated medical care model combined with psychological intervention can effectively improve the treatment effect of pulmonary tuberculosis patients with lung cancer and prevent the occurrence of adverse reactions; thus, it should be promoted in clinical practice.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45959977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Research on Treatment of Migraine with Combination of Characteristic and Superior Techniques of Zhuang Medicine","authors":"Yun Zhang, Yuying Lan, Yingcai Wei","doi":"10.26689/jcnr.v7i2.4789","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4789","url":null,"abstract":"Objective: To study the application effect of the combination of special advantages of Zhuang medical technology for migraine patients. Methods: 80 patients with migraine were selected and all were admitted to Mingxiu Branch of International Zhuang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine from February 2019 to February 2020. Random number table method was used to divide patients into two groups, with 40 patients in each group. Among them, the patients in the study group were treated with the therapy combining characteristics of Zhuang medicine and superior technology, that is, Zhuang medicine meridian tendon therapy + Zhuang medicine lotus needle cupping blood stasis removal therapy + Zhuang medicine thread moxibustion therapy + Zhuang medicine acupuncture therapy; the patients in the control group were treated with conventional Western medicine. The efficacy of the two treatments were compared. Results: After treatment, the total effective rate of clinical treatment in the study group was higher than that in the control group (P < 0.05), and the visual analogue scale (VAS) score and integral improvement rate were higher than those in the control group (P < 0.05). The onset time of action was statistically shorter than that of the control group (P < 0.05). There was a statistically significant difference in the adverse reaction rate between the two groups (P < 0.05). Conclusion: The combination of Zhuang medicine’s characteristic and superior techniques for patients with migraine has a significant curative effect.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48468004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress of the Application of “Internet+” Nursing in Patients with Liver Cancer","authors":"Rui Cao, Xiao-hua Song, Xi Chen","doi":"10.26689/jcnr.v7i2.4779","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4779","url":null,"abstract":"Objective: To explore the application effect of “Internet+” nursing in patients discharged from hospital after liver cancer operation. Methods: A total of 90 patients who underwent hepatocellular carcinoma resection in Shaanxi Provincial People’s Hospital from November 2019 to August 2020 were divided into an observation group (n = 45) and a control group (n = 45) randomly by drawing lots. The control group received routine discharge health guidance while the observation group underwent an “Internet+” nursing through hospital Internet information platforms, online consultation, and so on. Patients of both groups returned to the hospital one month after discharge and filled in the questionnaire. The incidence of adverse reactions, quality of life, and level of hope were compared between the two groups 1 month after discharge. Results: The incidence of adverse reactions in the observation group was significantly lower than that of the control group, and the difference was statistically significant (P < 0.05). The quality of life and level of hope of patients in the observation group were significantly higher than those in control group and the difference was statistically significant (P < 0.05). Conclusion: “Internet+” nursing service plays a positive role in improving the patients’ about their disease and their quality of life after discharge from hospital after liver cancer operation, which is worthy of popularization in clinical practice.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46234050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Effect of Shenghua Zhuyu Herbal Acupoint Plaster in the Treatment of Postpartum Malodor","authors":"Xia Zheng, Juan Shao, Liqin Zhi","doi":"10.26689/jcnr.v7i2.4818","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4818","url":null,"abstract":"Objective: To assess the clinical effect of Shenghua Zhuyu ointment, which was applied onto the Zhongji, Qihai, and Guanyuan acupoints, on postpartum lochia. Methods: We randomly divided 166 patients who were admitted in 2018–2021 into an observation group and a control group. The control group was treated with conventional clinical methods, whereas the observation group was treated by applying Shenghua Zhuyu ointment on the Zhongji, Qihai, and Guanyuan acupoints. The amount and duration of lochia, abdominal pain, hospitalization time were observed; B-scan ultrasonography was performed to check whether the placenta was discharged. Results: The treatment received by the observation group of patients was shown to be more effective than that of the control group. Besides, the experimental group had less lochia than that of the control group. The observation group also had shorter duration of lochia and hospital stay than those of the control group (P < 0.05). The placenta excretion was better, and the degree of abdominal pain was lower in the observation group than those of the control group (P < 0.05). Conclusion: The acupoint application of Shenghua Zhuyu herbal acupoint plaster has a significant impact on retained placenta, in which it can aid the discharge of residual placenta and improve the patients’ physical functions and symptoms.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48018748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the Different Frequencies of Transcutaneous Electrical Acupoint Stimulation for Postpartum Pelvic Girdle Pain","authors":"Duomei Ren, Chun-Lang Yang, Fenghua Yuan, Yanni Wang","doi":"10.26689/jcnr.v7i2.4801","DOIUrl":"https://doi.org/10.26689/jcnr.v7i2.4801","url":null,"abstract":"Objective: To observe the clinical effect of different frequencies of transcutaneous electrical acupoint stimulation in treating postpartum pelvic girdle pain and promoting postpartum rehabilitation. Methods: From January to September 2022, 300 patients with pelvic girdle pain after spontaneous delivery in a hospital in Shaanxi Province were selected and randomly divided into three groups, low frequency, high frequency, and alternating frequency, with 100 cases in each group. In addition to routine postpartum care and psychological counseling, the three groups received transcutaneous electrical acupoint stimulation at low-frequency (2 Hz,) high-frequency (100 Hz), and alternating frequency (2/100 Hz), respectively. The differences in initial pain, pain scores before and after treatment, satisfaction with analgesic effect, and postpartum rehabilitation effect were evaluated among the three groups of patients. Results: There was a significant correlation between maternal age and postpartum pelvic girdle pain (P < 0.001), but no correlation was observed between newborn birth weight and postpartum pelvic girdle pain (P > 0.05). After 1d/2d of treatment, the pain scores and rehabilitation effect of patients in the alternating-frequency group and low-frequency group were significantly better than those in the high-frequency group, and the postpartum curative effect of patients in the alternating-frequency group was the best, followed by the low-frequency group, and the high-frequency group; the differences were statistically significant (P < 0.001). Among the three groups, the alternating-frequency group had the highest satisfaction with the analgesic effect and the highest rate of selecting the same analgesic regimen the next time; the differences were statistically significant (P < 0.001). Conclusion: Transcutaneous electrical acupoint stimulation at different frequencies is safe and effective in treating postpartum pelvic girdle pain and beneficial to postpartum rehabilitation. Sparse-dense wave stimulation is effective in treating postpartum pelvic girdle pain. It has the best effect in promoting postpartum rehabilitation and the highest patient satisfaction. Therefore, its application in clinical practice is highly recommended.","PeriodicalId":64151,"journal":{"name":"临床护理研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46503326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}