{"title":"Analysis results of prognostic factors affecting survival outcome for locoregional recurrence in postmastectomy of breast cancer","authors":"Zhiqiang Zhang, Sha Shi, Lili Liu, Tong Wu, Xiaoqi Li, Jing Shi, Lingyun Zhang, Lijie He","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.03.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.03.006","url":null,"abstract":"Objective \u0000To investigate the prognostic factors affecting survival outcome for locoregional recurrence in postmastectomy of breast cancer. \u0000 \u0000 \u0000Methods \u0000A retrospective study was performed on 61 breast cancer patients who suffering outcome of locoregional recurrence(LRR)treated by modified radical mastectomy.The clinical data of LRR patients with breast cancer and distant metastasis and clinical pathologic factors of survival were analyzed. \u0000 \u0000 \u0000Results \u0000Univariate analysis showed that triple-negative breast cancer, HER2-enriched breast cancer, time to LRR less than 2 years, no surgical removal of the lesions of LRR were correlated to survival outcome for LRR in postmastectomy of breast cancer.Multivariate analysis revealed that triple-negative breast cancer, HER2-enriched breast cancer, no surgical removal of the lesions of LRR were independent risk factors influencing risk of distant metastasis for LRR in postmastectomy of breast cancer.Among them, the risks of distant metastasis of triple-negative breast cancer, HER2-enriched breast cancer after LRR are 3.58 times and 2.87 times more than Luminal A/B(HER2-negative)breast cancer.In addition, triple-negative breast cancer, HER2-enriched breast cancer were independent risk factors influencing overall survival after LRR, their risk of death were 3.886 times and 3.097 times more than Luminal A/B(HER2-negative)breast cancer. \u0000 \u0000 \u0000Conclusion \u0000LRR of breast cancer after mastectomy correlates with a high risk of distant metastasis events and death in particular in patients with triple-negative and HER2-enriched breast cancer.Radiotherapy and mastectomy for LRR are warranted to reduce the risk of distant metastasis. \u0000 \u0000 \u0000Key words: \u0000Triple-negative breast cancer; HER2-enriched breast cancer; Locoregional recurrence; Modified radical mastectomy; Breast cancer","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"26-33"},"PeriodicalIF":0.0,"publicationDate":"2017-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44674520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-04-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.02.010
Shiyu Wang, De-Jun Yuan, Fanghong Gu
{"title":"Effect of helicobacter pylori infection in gastric cancer","authors":"Shiyu Wang, De-Jun Yuan, Fanghong Gu","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.02.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.02.010","url":null,"abstract":"Objective \u0000To investigate the difference between gastric cancer samples without helicobacter pylori infection and gastric cancer samples infected with helicobacter pylori in gastric cancer samples. \u0000 \u0000 \u0000Methods \u0000Data of gastric cancer gene expression(MRNA)in TCGA database were extracted.According to the presence or absence of helicobacter pylori infection in gastric cancer samples, the samples were divided into two groups.The expression data was compared by edgeR algorithm and the differential genes were obtained.And then the two groups of different genes were analyzed by enrichment.Finally, the results of enrichment analysis were compared between the two groups to find the difference between the gastric cancer samples without helicobacter pylori infection and the gastric cancer samples infected with helicobacter pylori infection. \u0000 \u0000 \u0000Results \u0000The KEGG database showed that there were significant differences in metabolic pathways, protein digestion and uptake, fat digestion and uptake, gastric acid secretion, pancreatic secretion, cAMP signaling pathway, and vascular smooth muscle contraction in gastric cancer samples without helicobacter pylori infection(P<0.000 01). There was a significant difference in the cytokine-cytokine receptor interaction with gastric cancer samples with helicobacter pylori infection(P<0.000 01). \u0000 \u0000 \u0000Conclusion \u0000Helicobacter pylori infection promotes the abnormalities of cytokine-cytokine receptor interactions.There may be two different gastric cancer, respectively, for the metabolic pathway, protein digestion and absorption, fat digestion and absorption, gastric acid secretion, pancreatic secretion, cAMP signaling pathway, vascular smooth muscle contraction and cytokine-cytokine receptor Interaction has an impact. \u0000 \u0000 \u0000Key words: \u0000Gastric cancer; Helicobacter pylori; EdgeR algorithm","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"42-47"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48119079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3D printing technology in the treatment of traumatic hip fracture with the help of 3D-CT classification","authors":"Wenqian Xu, Zhencun Cai, Y. Mei, Meihuan Wang, Yong Ma, Chengzhe Piao","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.02.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.02.008","url":null,"abstract":"Objective \u0000To evaluate 3D print model and spiral 3D-CT reconstruction parting in hip fracture diagnostic and therapeutic application value. \u0000 \u0000 \u0000Methods \u0000A retrospective study was performed on diagnosis by 3D print model, 3D-CT and X-ray of 46 patients with hip joint fracture.According to the model of 3D printing, X-ray imaging, the 3D-CT imaging data, fracture classification according to the following standards: Type Ⅰ, acetabulum fracture without displacement; Type Ⅱ, acetabulum anterior column and(or)front wall fracture displacement less than 4 mm, column and(or)wall fracture displacement less than 4 mm, top of the acetabulum fracture displacement less than 2 mm; Type Ⅲ, acetabulum anterior column and(or)front wall fracture displacement more than 4 mm, wall column and(or)after fracture displacement more than 4 mm, top of the acetabulum fracture displacement more than 2 mm; Type Ⅳ, double column or T fracture, fracture type central dislocation; Type Ⅴ, acetabulum fracture combination of femoral neck fracture and(or)intra-articular loose bodies, pelvic fractures.Patients with Type Ⅰ and Ⅱ received conservative treatment, such as traction, patients with Type Ⅲ, Ⅳ, Ⅴ received anterior or posterior surgery.All patients were followed up for 6 months on average, and follow-up data was integrity.Harris score method was used to evaluate the function of hip joint. \u0000 \u0000 \u0000Results \u0000There was significant difference between X-ray and 3D model(P=0.012), there was no significant difference between CT and 3D model(P=0.083). Type Ⅰ was 3 cases, Type Ⅱ was 5 cases, Type Ⅲ was 16 cases, Type Ⅳ was 12 cases, Type Ⅴ was 10 cases.According to Harris score, excellent was 35 cases, good was 7 cases, fair was 4 cases, and the excellent and good rate was 91%; there was no significant difference in the long-term excellent and good rate of patients with Type Ⅲ, Ⅳ, Ⅴ(P=0.102, 0.079, 0.059). \u0000 \u0000 \u0000Conclusion \u0000The traditional Jndt and Letoume1 classification process is complicated and the angle has certain limitation, which has not considered the acetabulum weight-bearing area fracture, the joint free bone block as well as the head and neck, the pelvis fracture and so on.Three-dimensional reconstruction spiral CT classification has some guiding significance for the clinical treatment of hip fracture. \u0000 \u0000 \u0000Key words: \u0000Fracture of hip joint; 3D print technology; X-ray; Three-dimensional reconstruction spiral CT","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"33-37"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46213992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-04-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.02.007
He-hua Li
{"title":"Study on the relationship between serum anti Mullerian hormone and polycystic ovary syndrome and ovarian hyper response","authors":"He-hua Li","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.02.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.02.007","url":null,"abstract":"Objective \u0000To investigate the diagnostic value of serum anti Mullerian hormone(AMH)value in the diagnosis of polycystic ovary syndrome(PCOS)and the prediction of ovarian hyper response during controlled ovarian hyperstimulation(COH). \u0000 \u0000 \u0000Methods \u0000A total of 535 people were enrolled in the study, including PCOS group(n=290)and control group(n=245). The patients were divided into four groups according to age, and the basic hormones(T, P, LH, FSH, E2)ands erum AMH were compared.A total of 138 people were treated with IVF/ICSI, and the control group was 71 people, with a total of 66 people in the PCOS group.Through the analysis of AMH, BMI, GN dosage, medication time, HCG day P, HCG day LH, HCG day E2, the predictive value of AMH in high ovarian response was compared. \u0000 \u0000 \u0000Results \u0000AMH as the diagnostic criteria of PCOS was statistically significant(P<0.001). Cut-off value of the whole age group was 5.94 ng/mL, sensitivity was 0.738, specificity was 0.747.AMH was positively correlated with ovarian high response to moderate intensity(r=0.498, P<0.001). The predictive value of AMH for ovarian hyper response was 5.72 ng/mL(P<0.05), with a sensitivity of 0.714 and a specificity of 0.833.The predictive value of AMH for ovarian hyper response in patients with PCOS was 9.74 ng/ml(P<0.05), with a sensitivity of 0.833 and a specificity of 0.727. \u0000 \u0000 \u0000Conclusion \u0000AMH has some value in the diagnosis of PCOS, and can be used as an indicator to predict the ovarian response in PCOS patients. \u0000 \u0000 \u0000Key words: \u0000AMH; PCOS; COH; High ovarian response","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"26-32"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41959881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-02-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.01.008
Wen. Zhao, Lizhu Deng, S. Duan, Hua Zhong
{"title":"Imaging anatomy and research of ponticulus posticus with three-dimensional CT","authors":"Wen. Zhao, Lizhu Deng, S. Duan, Hua Zhong","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.01.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.01.008","url":null,"abstract":"Objective \u0000To use three-dimensional CT display ponticulus posticus(PP), make the classification and measurement of PP, and provide the anatomical basis for the related application. \u0000 \u0000 \u0000Methods \u0000A total of 63 cases of PP were found from CT angiography(CTA)of head and neck in our hospital of PACS system from January 2008 to December 2014.On the three-dimensional images, these parameters of PP were measured, including the anteroposterior diameter(AD), vertical diameter(VD), breakpoint distance(BD), third segment diameter of VA(D-VA), the distance between peak of groove ring and occipital(D-RO), the distance of groove ring to midline diameter(D-RL), distance from posterior arch nodule of atlas to the occipital bone(D-NO). \u0000 \u0000 \u0000Results \u0000Three-dimensional CT found the PP in 63 cases with 104 sides, which male of 53 cases, female of 10 cases, left side PP of 49 sides, including the complete type of 23 sides and incomplete type 26 and the right PP of 55 sides, including complete type 22 sides and incomplete type 33.In the left PP, measurements of AD, VD, BD, D-VA, D-RO, D-NO and D-RL were(5.02±1.17)mm, (3.59±1.26)mm, (3.91±2.51)mm, (3.88±0.78)mm, (2.15±2.58)mm, (18.62±3.01)mm and(5.19±3.32)mm, respectively, the right PP were(5.13±1.29)mm, (3.87±0.88)mm, (4.02±2.77)mm, (3.59±0.89)mm, (2.14±2.63)mm, (4.89±3.36)mm, (18.89±3.74)mm and(4.8±3.36)mm, respectively.Statistical comparison showed that AD of PP was greater than VD, D-VA, bilateral BD of PP was greater than that of the unilateral and D-VA, while unilateral BD of PP was less than D-VA, VD, D-RL of complete type PP were less than that of incomplete, D-RO, D-NO of complete type PP were greater than that of incomplete. \u0000 \u0000 \u0000Conclusion \u0000CT three-dimensional imaging can clearly and directly display the PP.Incidence of PP in the male is more than the female.The typing, incidence, size and shape of PP in the left are similar the right.AD of PP is greater than VD, which may limit the VA activities in vertical direction, especially that of complete PP.The PP opening of incomplete type in the bilateral is larger than in the unilateral, which may relate to the degree of degradate evolution. \u0000 \u0000 \u0000Key words: \u0000Ponticulus posticus; Vertebral artery; Anatomy measurement; Three-dimensional CT","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"27-32"},"PeriodicalIF":0.0,"publicationDate":"2017-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42512874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-02-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.01.002
Xiang-xin Zhan, X. Sui
{"title":"Chinese and westem medicine treatment progress of upper limb lymphedema after breast cancer surgery","authors":"Xiang-xin Zhan, X. Sui","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.01.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.01.002","url":null,"abstract":"","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"2-10"},"PeriodicalIF":0.0,"publicationDate":"2017-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48478575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-02-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.01.007
Lingwei Ju, H. Tao, Zhaozhe Liu, Yong-ye Liu, Xiaodong Xie
{"title":"Shenqifuzheng injection combined with CEF in the treatment of breast cancer","authors":"Lingwei Ju, H. Tao, Zhaozhe Liu, Yong-ye Liu, Xiaodong Xie","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.01.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.01.007","url":null,"abstract":"Objective \u0000To observe the effect of Shenqifuzheng injection on immune and hematopoietic function in patients with breast cancer during chemotherapy. \u0000 \u0000 \u0000Methods \u0000A retrospective study was performed on 98 cases of breast cancer who were admitted from August 2014 to August 2016.Patients who received postoperative CEF chemotherapy(cyclophosphamide, pharmorubicin, fluorouracil)were divided into two the observation group(n=50)and the control group(n=48). Patients in the control group were treated with CEF, patients in the observation group were added with Shenqifuzheng injection on the basis of the control group.The changes of peripheral blood cells and T cell subsets between the two groups before and after chemotherapy were compared. \u0000 \u0000 \u0000Results \u0000The white blood cell, hemoglobin and platelet in the observation group before and after chemotherapy were slightly reduced, and the differences were not statistically significant(P>0.05), the white blood cells, hemoglobin and platelet in the control group reduced significantly after chemotherapy, and the differences were statistically significant(P<0.05); CD4, CD8 and CD4/CD8 in the observation group and the control group were obviously changed before and after chemotherapy, data in the observation group was significantly increased, while in the control group was significantly reduced(all P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Chemotherapy combined with Shenqifuzheng injection can improve immune function and reduce bone marrow suppression in patients with breast cancer. \u0000 \u0000 \u0000Key words: \u0000Shenqifuzheng injection; Breast cancer; Chemotherapy; Immunity","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"23-26"},"PeriodicalIF":0.0,"publicationDate":"2017-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43862935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-02-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.01.006
Lingling Chen, H. Tao, Liu Zhaozhe, Guanzhong Zhang, Zhendong Zheng
{"title":"Jiaweixuanfudaizhe decoction in preventing and treating digestive tract reaction of chemotherapy for breast cancer: a clinical study on 78 cases","authors":"Lingling Chen, H. Tao, Liu Zhaozhe, Guanzhong Zhang, Zhendong Zheng","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.01.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.01.006","url":null,"abstract":"Objective \u0000To explore the effect of Jiaweixuanfudaizhe decoction in preventing and treating digestive tract reaction of chemotherapy for breast cancer. \u0000 \u0000 \u0000Methods \u0000A total of 78 patients with breast cancer who underwent chemotherapy were randomly divided into the treatment group and the control group, 39 cases in each group.Patients in both groups were given palonosetron, patients in the treatment group were given Jiaweixuanfudaizhe decoction 1 day before chemotherapy, and the effects after 7 continuous doses were compared. \u0000 \u0000 \u0000Results \u0000There were 12 cases did not appear nausea or mild nausea in the control group and 24 cases did not appear nausea or mild nausea in the treatment group, and there was statistically significant difference between the two groups(P<0.01); the antiemetic efficiency in the control group was 35.9%(14/39)and in the treatment group was 61.5%(24/39), and there was statistically significant difference between the two groups(P<0.05). \u0000 \u0000 \u0000Conclusion \u0000The Jiaweixuanfudaizhe decoction can effectively prevent and treat the digestive tract reaction of chemotherapy for breast cancer. \u0000 \u0000 \u0000Key words: \u0000Breast cancer; Jiaweixuanfudaizhe decoction; Chemotherapy; Digestive tract reaction","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"8 1","pages":"20-22"},"PeriodicalIF":0.0,"publicationDate":"2017-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48964309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2017-02-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2017.01.011
R. Ren
{"title":"Exogenous type CSP cesarean section the safety of the application of combined hysteroscopy surgery in uterine artery embolization and application value","authors":"R. Ren","doi":"10.3760/CMA.J.ISSN.1673-8799.2017.01.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2017.01.011","url":null,"abstract":"Objective \u0000To investigate the clinical value and safety of uterine artery embolization combined with hysteroscopy in the treatment of uterine scar pregnancy after cesarean section. \u0000 \u0000 \u0000Methods \u0000A total of 84 patients uterine scar pregnancy were selected after cesarean section cases with surgical treatment from January 2015 to January 2016 in Heze city of Shandong province maternal and child health care. According to the random principle, the cases were divided into two groups, all patients underwent hysteroscopic surgery, control group received intramuscular injection of methotrexate, and observation group underwent bilateral uterine artery embolization, compared between the two groups in operative time, bleeding volume, postoperative first anal exhaust time, postoperative blood HCG clearance time, total length of time, the lesion disappeared, menstrual recovery time and adverse reaction incidence rate. \u0000 \u0000 \u0000Results \u0000Control group of operative time, postoperative first anal exhaust time and total hospital stay were longer than observation group, and bleeding volume also was more than in the observation group, the differences were statistically significant(P 0.05). \u0000 \u0000 \u0000Conclusion \u0000For patients with uterine scar pregnancy after cesarean section, undergoing hysteroscopy surgery also combined with uterine artery embolization can effectively improve the operation efficiency, reduce injury to patients, help patients recovery from the illness, and adverse reaction rate is low, the operation is safe and reliable, it is worth clinical promotion. \u0000 \u0000 \u0000Key words: \u0000Cesarean section; Uterine scar pregnancy; Arterial embolization; Hysteroscopy","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":" ","pages":"42-45"},"PeriodicalIF":0.0,"publicationDate":"2017-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42547638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国临床实用医学Pub Date : 2016-12-25DOI: 10.3760/CMA.J.ISSN.1673-8799.2016.06.006
Guan Li, Mingyu Zou, Benqiang Yang
{"title":"Feasibility study of CT enhanced 100 KVP scan on liver tri-phase enhancement","authors":"Guan Li, Mingyu Zou, Benqiang Yang","doi":"10.3760/CMA.J.ISSN.1673-8799.2016.06.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-8799.2016.06.006","url":null,"abstract":"Objective \u0000To explore the feasibility of 100 KVP on liver tri-phase enhancement scan. \u0000 \u0000 \u0000Methods \u0000A total of 60 patients whose BMI from 20 - 25 kg/m2 with suspected liver disease underwent tri-phase enhanced CT scans divided into two groups randomly, and each group includes 30 cases. Low dose group were scanned with 100 KVP and auto modulation tube current(peak current 600 mA). CT image raw data sets were reconstructed with ASIR composite at 50%. Normal dose group were scanned with 120 KVP and 250 mA. CT image raw data sets were reconstructed with FBP. Contrast medium injection rate and volume were personalized by patients' weight (350 mgI/ml). The effective radiation dose (ED) of each patient was calculated. Image quality evaluation was assessed objectively and subjectively. \u0000 \u0000 \u0000Results \u0000There was no statistically significant difference in subjective and objective image quality between the two groups (P>0.05). Patients in low dose group suffered an average effective radiation dose which was obviously lower than that normal dose group (3.06 mSv vs 3.69 mSv, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Those BMI from 20 - 25 kg/m2 underwent liver tri-phase enhancement with 100 KVP may obtain better image quality and less than radiation dose, and could got the image quality to meet the needs of clinical diagnosis. \u0000 \u0000 \u0000Key words: \u0000Tomography; X-ray computed; Abdominal scanning; Low dose","PeriodicalId":64135,"journal":{"name":"中国临床实用医学","volume":"7 1","pages":"21-24"},"PeriodicalIF":0.0,"publicationDate":"2016-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69975001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}