病理学期刊(英文)最新文献_第4页

Rhabdomyosarcoma in Dakar: An Update on Pronostics Factors 达喀尔横纹肌肉瘤:Pronostics因素的最新进展

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.121005

A. Gaye, Marie Joseph Dieme-Haouidi, I. Thiam, Fabrice Senghor, G.N.C. Deguenonvo, C. Dial

{"title":"Rhabdomyosarcoma in Dakar: An Update on Pronostics Factors","authors":"A. Gaye, Marie Joseph Dieme-Haouidi, I. Thiam, Fabrice Senghor, G.N.C. Deguenonvo, C. Dial","doi":"10.4236/ojpathology.2022.121005","DOIUrl":"https://doi.org/10.4236/ojpathology.2022.121005","url":null,"abstract":"Rhabdomyosarcoma (RMS) belongs to the soft tissue sarcomas that have striated muscle differentiation. It is most common in young children under 5 years of age and adolescents. The definite diagnosis of rhabdomyosarcoma is based on histology and the positivity of striated muscle markers in immuno-histochemistry. Our objective was to describe the prognostic characteristics of RMS diagnosed in Dakar. MATERIAL AND METHODS: This was a retrospective and descriptive study spread over nine (09) years from 1 January 2011 to 31 December 2019. It was conducted from the histological report archives of the anatomy and pathology laboratories of Dakar. Paraffin blocks were reread and immunohistochemically studied by manual method. Antidesmin and antimyogenin antibodies were used. RESULTS: We collected 44 patients with rhabdomyosarcoma out of 228 cases of soft tissue cancers, i.e. 19.29% of all malignant soft tissue tumours. The mean age of the patients was 25.41 ± 23.95 (standard deviation) years with a median age of 16 years and extremes of 6 months and 81 years. Patients were less than or equal to 17 years of age in 61.4% was statistically significant (p = 0.039). A relationship was also observed between histological type and site (p = 0.026). According to the American IRS classification, the tumour was classified as group I in 41% of cases, group II in 50% of cases and groups III and IV in 4.5% each. CONCLUSION: Rhabdomyosarcoma is a rare malignant tumour in Dakar. It is often a voluminous tumour of the limbs which affects mainly males. The embryonal type is the most frequent histological form.","PeriodicalId":57444,"journal":{"name":"病理学期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70495286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Primary Bilateral Adenocarcinoma of the Fallopian Tube: A Case Report 原发性双侧输卵管腺癌1例报告

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.124016

Z. I. Raivoherivony, L. Nomenjanahary, F. N. Rakotondrainibe, N. Randrianjafisamindrakotroka

引用次数: 0

Focal Segmental Glomerulosclerosis in Côte d’Ivoire: Epidemiological, Clinical and Pathological Aspects Côte科特迪瓦局灶节段性肾小球硬化:流行病学，临床和病理方面

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.124017

N. Justin, Tia Weu Melanie, A.S.L. De Randorphe, Lagou Delphine Amelie, Touré Ibrahiman, Kobenan Atta Anne Rebecca, Abouna Alain Didier, Guei Monley Cyr, Tuo Wako Tianwa Alice, Oka Kouamé Hubert, Diopo Sery Patrick Olivier, Delma Samuel, Cherif Ibrahima, Traoré Moussa, Amekoudi Eyram, Ouattara Belarsi Safiatou, Y. K. Hubert, A. Clément, Adonis Koffi Laurence, Yao Gnangoran Victor, Gnionsahie Dazé Apolinaire, M.I. Jean-Marie Diomandé

引用次数: 0

Clival Salivary Heterotopia (Salivary Choristoma): A Rare Radiopathogical Lesión 阴唇唾液异位:一种罕见的放射病理学Lesión

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.124013

J. Ortiz, J. C. Paniagua, L. Chinchilla, Enrique Montero, E. Muñoz, María Dolores Ludeña

引用次数: 0

Evaluation of OLGA and OLGIM Systems in Madagascar, a Country with Low Economic Resources 低经济资源国家马达加斯加OLGA和OLGIM系统评价

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.124015

M.R. Rabarison, L. Nomenjanahary, N. Randrianjafisamindrakotroka

{"title":"Evaluation of OLGA and OLGIM Systems in Madagascar, a Country with Low Economic Resources","authors":"M.R. Rabarison, L. Nomenjanahary, N. Randrianjafisamindrakotroka","doi":"10.4236/ojpathology.2022.124015","DOIUrl":"https://doi.org/10.4236/ojpathology.2022.124015","url":null,"abstract":"Chronic gastritis is a persistent inflammation of the gastric mucosa. The Sydney System is the most widely used classification of this disease but it does not allow a ranking of patients according to the evolutionary potential of the disease, unlike the classifications: “Operative Link On Gastritis Assessment” (OLGA) and “Operative Link on Gastritis Intestinal Metaplasia Assessment” (OLGIM). Our goals are to apply and evaluate the three classifications: the Sydney System, OLGA and OLGIM and to draw possible correlations. This is a retrospective, descriptive, single-center study performed on all cases of chronic gastritis, diagnosed at the laboratory of Pathological Anatomy Unit of Joseph Ravoahangy Andrianavalona University Hospital from January 1, 2013 to December 31, 2017. A review and application of the three main classification systems was performed on each case. We included 298 cases. The mean age was 50.85 years. The sex ratio was 1.48. The high-risk stages according to the “Operative Link On Gastritis Assessment” (OLGA) system and the “Operative Link on Gastritis Intestinal Metaplasia Assessment” (OLGIM) system were 0.67% and 2.68%, respectively. We observed a correlation between the two systems with discordance of 5%. The use of the two new systems allows the assessment of the progressive potential of gastritis in patients at risk of developing gastric cancer. For optimal effectiveness of both classifications, biopsies should be performed according to the Sydney System recommendations.","PeriodicalId":57444,"journal":{"name":"病理学期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70495289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clear Cells Carcinoma of Thyroid: Difficult Diagnosis and Rare Case 甲状腺透明细胞癌:诊断困难及罕见病例

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.122006

A.H. Tiana, R. Francine, V.H. Angelo, R. Soa

引用次数: 0

Epidemiological and Clinical Characteristics of Renal Diseases Diagnosed by Biopsies in Ivory Coast 科特迪瓦活检诊断肾脏疾病的流行病学和临床特征

病理学期刊(英文) Pub Date : 2022-01-01 DOI: 10.4236/ojpathology.2022.123012

K. J. N’dah, W. M. Tia, A. Abouna, Ibrahima Toure, Amélie-Delphine Lagou, Monley Guei, I. Cherif, Moussa Traoré, E. Amekoudi, Attaah Ange Rebecca Kobenan, S. Diopo, K. H. Yao, N. C. Ackoundou, Koffi Laurence Adonis, D. A. Gnionsahié, M. Diomandé

引用次数: 1

Immunohistochemical Expression of Surviving in Viral Hepatitis and Hepatocellular Carcinoma, a Comparative Study 存活在病毒性肝炎和肝细胞癌中的免疫组织化学表达的比较研究

病理学期刊(英文) Pub Date : 2021-07-28 DOI: 10.4236/ojpathology.2021.114008

E. Matar, M. Goda

{"title":"Immunohistochemical Expression of Surviving in Viral Hepatitis and Hepatocellular Carcinoma, a Comparative Study","authors":"E. Matar, M. Goda","doi":"10.4236/ojpathology.2021.114008","DOIUrl":"https://doi.org/10.4236/ojpathology.2021.114008","url":null,"abstract":"Hepatocellular carcinoma (HCC) is the fifth most common neoplasm, the major cause of death in patients with cirrhosis, and the third most common cause of cancer-related death in the world. In Egypt, hepatocellular carcinoma (HCC) is the second most common cancer in men and the 6th most common cancers in women. Egypt has the highest prevalence of HCV in the world and the prevalence of HCC is increasing in the last years. Nowadays, HCV infection and its complications are among the leading public health challenges in Egypt with 13.8% of population infected and, in these patients, the risk of HCC is increased 17-fold. Glypican-3 (GPC3) is a member of heparin sulfate proteoglycan family which is linked to cell surface. It plays an important role in regulation of cell growth, differentiation, and migration. It is normally expressed in fetal liver and placenta but not in normal adult liver tissue. 8-Hydroxydeoxyguanosine (8-OHdG) is an oxidatively modified promutagenic DNA that is produced by oxygen radicals and is recognized as a useful marker in estimating DNA damage induced by oxidative stress. The present work is a retrospective, cross-sectional, study performed on 150 liver paraffin blocks that included 100 cases of chronic hepatitis C and 50 cases of hepatocellular carcinoma. These cases were collected from the Pathology Department. The 100 cases of chronic hepatitis C were graded into low grade chronic hepatitis (58) cases and high-grade chronic hepatitis (42) cases, 30 patients had cirrhosis, all in the high-grade group. The 50 cases of hepatocellular carcinoma (HCC) included 18 cases of well-differentiated HCC (grade I), 22 cases of moderately differentiated HCC (grade II) and 10 cases of poorly differentiated HCC (grade III). Among 50 cases of HCC, 44 cases showed cirrhosis in the non-neoplastic liver tissue. There was a statistically significant difference in 8-OHdG index between chronic hepatitis and hepatocellular carcinoma (P = 0.006).","PeriodicalId":57444,"journal":{"name":"病理学期刊(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42094285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Ewing’s Sarcoma Arising in the Cervical Spine with an Elevation of Serum ProGRP 伴有血清ProGRP增高的颈椎尤文氏肉瘤1例

病理学期刊(英文) Pub Date : 2021-07-28 DOI: 10.4236/ojpathology.2021.114009

R. Aoki, Yoshikazu Ikoma, Asuka Ohashi, Riyoko Niwa, Fumumasa Etori, M. Matsuyama, A. Onogi, N. Watanabe, Takuji Tanaka

引用次数: 0

Prediction of Nipple and Areola Complex Invasion in Breast Cancer Patients. Clinical and Pathological Study of Surgical Specimens 癌症患者乳头和乳头复合体侵袭的预测。外科标本的临床病理学研究

病理学期刊(英文) Pub Date : 2021-06-01 DOI: 10.4236/OJPATHOLOGY.2021.113006

M. Goda, Mostafa Abdel Rahman, E. Matar

引用次数: 1