Food Science and Biotechnology最新文献_第3页

Thymol promotes cell proliferation and protects against LPS-induced intestinal inflammation via activation of the EGFR/PI3K pathway 百里香酚通过激活EGFR/PI3K通路，促进细胞增殖，防止lps诱导的肠道炎症

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-24 DOI: 10.1007/s10068-025-01833-y

Xin Wen, Ziwen Ma, Lujia Gao, Nan Gao, Na Dong, Licong Zhang, Anshan Shan, Xiujing Dou

{"title":"Thymol promotes cell proliferation and protects against LPS-induced intestinal inflammation via activation of the EGFR/PI3K pathway","authors":"Xin Wen, Ziwen Ma, Lujia Gao, Nan Gao, Na Dong, Licong Zhang, Anshan Shan, Xiujing Dou","doi":"10.1007/s10068-025-01833-y","DOIUrl":"10.1007/s10068-025-01833-y","url":null,"abstract":"<div><p>Sepsis-induced intestinal inflammation affects the rapid turnover of intestinal epithelial cells, disrupting the intestinal barrier. Thymol (THY), as a plant-derived active component, is involved in protecting the intestinal barrier, but the specific mechanisms are still unclear. In this research, thymol increases the amount of cells and enhances the proliferative activity, notably in the G2/M phase of IPEC-J2 cells. Molecular docking indicated that pocket-like binding of thymol with epidermal growth factor receptor (EGFR) protein. Inhibition of EGFR expression diminished the cell proliferation viability after thymol treatment. In vivo, thymol prevented LPS-induced reduction in jejunal villi length, impairment of MUC2 and TFF3, decreased levels of Reg 3β and Reg 3γ, and elevated the pro-inflammatory cytokines. Moreover, thymol inhibited the EGFR-PI3K/AKT and NF-κB pathways and mitigated intestinal cell inflammation and apoptosis. Collectively, thymol inhibited apoptosis by regulating intestinal barrier and activating the EGFR-PI3K/AKT signaling pathway, providing evidence for alleviating intestinal inflammation under sepsis.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 10","pages":"2281 - 2294"},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143929947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activation of hepatic alcohol metabolism by enzymatic porcine placenta hydrolysate in rats 猪胎盘酶解物对大鼠肝脏酒精代谢的激活作用

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-24 DOI: 10.1007/s10068-025-01822-1

Jaeeun Shin, Ji-Sun Kim, Young Jae Jung, Yeonho Lee, Haeyoung Yoo, Seong Hun Ju, Daehyeon Sim, Yebean Kim, Gun Won Bae, Sun Myung Yoon, Sung-Joon Lee

{"title":"Activation of hepatic alcohol metabolism by enzymatic porcine placenta hydrolysate in rats","authors":"Jaeeun Shin, Ji-Sun Kim, Young Jae Jung, Yeonho Lee, Haeyoung Yoo, Seong Hun Ju, Daehyeon Sim, Yebean Kim, Gun Won Bae, Sun Myung Yoon, Sung-Joon Lee","doi":"10.1007/s10068-025-01822-1","DOIUrl":"10.1007/s10068-025-01822-1","url":null,"abstract":"<div><p>Alcohol consumption causes severe liver damage and oxidative stress. This study investigated the hepatoprotective effects of enzymatic porcine placenta hydrolysate (EPPH) in Sprague–Dawley rats under acute alcohol administration. EPPH significantly reduced plasma ethanol and acetaldehyde levels in a dose-dependent manner. Furthermore, EPPH decreased the hepatic levels of malondialdehyde and thiobarbituric acid reactive substances and suppressed <i>Cyp2e1</i> mRNA expression. EPPH decreased the plasma alanine transaminase and aspartate transaminase levels and increased the hepatic NAD<sup>+</sup>/NADH ratio. Hepatic transcriptome analysis revealed the significant regulation of key genes involved in inflammation, alcohol response, and apoptosis. Phosphokinase array analysis demonstrated that EPPH reduced phosphorylation of CASP9, BAX, TP53, and CHK2, thereby facilitating reactive oxygen species removal and suppressing apoptosis. Additionally, qPCR confirmed EPPH reduced <i>Bax</i> and <i>Caspase9</i> mRNA levels, while immunoblotting showed decreased phosphorylation of TP53 and CHK2. These findings suggest that EPPH improves hepatic alcohol metabolism and reduces alcohol-induced hepatotoxicity.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 9","pages":"2025 - 2038"},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of poly-γ-glutamic acid addition and pH changes on the 3D-food printability of cookie dough 聚γ-谷氨酸添加量和pH变化对饼干面团3d食品打印性能的影响

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-20 DOI: 10.1007/s10068-025-01837-8

Ha Eun Jeong, Chang Joo Lee, Sea C. Min

引用次数: 0

Paeonol from Paeonia lactiflora attenuates calcification of aortic valvular interstitial cell by inhibiting activation of redox-sensitive NFκB/AKT/ERK1/2 pathway 白芍丹皮酚通过抑制氧化还原敏感的NFκB/AKT/ERK1/2通路的激活，减轻主动脉瓣间质细胞的钙化

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-20 DOI: 10.1007/s10068-025-01838-7

Yeon-Hyang Gwak, Saugat Shiwakoti, Ju-Young Ko, Hwan-Hee Sim, Ji-Hyeok Lee, Hyun Jung Kim, Min-Ho Oak

{"title":"Paeonol from Paeonia lactiflora attenuates calcification of aortic valvular interstitial cell by inhibiting activation of redox-sensitive NFκB/AKT/ERK1/2 pathway","authors":"Yeon-Hyang Gwak, Saugat Shiwakoti, Ju-Young Ko, Hwan-Hee Sim, Ji-Hyeok Lee, Hyun Jung Kim, Min-Ho Oak","doi":"10.1007/s10068-025-01838-7","DOIUrl":"10.1007/s10068-025-01838-7","url":null,"abstract":"<div><p>Calcific aortic valve disease (CAVD) is a life-threatening cardiovascular condition without effective pharmacological treatments. Paeonol, a bioactive compound from the roots of <i>Paeonia lactiflora</i>, is known for its anti-inflammatory, antioxidant, and anti-atherosclerotic properties. While it has shown benefits in treating several cardiovascular conditions, its role in CAVD remains unexplored, requiring further investigation. This study explores paeonol's potential to inhibit calcification in porcine valve interstitial cells (VICs) and to elucidate the underlying mechanism. Calcification was induced using a pro-calcifying medium (PCM), and the anti-calcification effects of paeonol were evaluated. Paeonol significantly reduced level of calcification and its markers such as RUNX2, osteopontin, and BMP2. It also lowered reactive oxygen species levels, thereby reducing oxidative stress, which is known to activate several calcification pathways. Paeonol inhibited these pathways by reducing phosphorylation of NFκB, AKT, and ERK1/2, thereby preventing their activation and suggesting its potential as a therapeutic agent to mitigate CAVD progression.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 10","pages":"2269 - 2279"},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143929987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancement of iminosugar production, 1-deoxynojirimycin and 1-deoxymannojirimycin, in recombinant Corynebacterium glutamicum 重组谷氨酸棒状杆菌中亚糖、1-脱氧诺吉霉素和1-脱氧甘露诺吉霉素产量的提高

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-15 DOI: 10.1007/s10068-025-01834-x

Inonge Noni Siziya, Hyo Jung Lim, Dong-Hyun Jung, Suhyeon Baek, Sanggil Lee, Myung-Ji Seo

{"title":"Enhancement of iminosugar production, 1-deoxynojirimycin and 1-deoxymannojirimycin, in recombinant Corynebacterium glutamicum","authors":"Inonge Noni Siziya, Hyo Jung Lim, Dong-Hyun Jung, Suhyeon Baek, Sanggil Lee, Myung-Ji Seo","doi":"10.1007/s10068-025-01834-x","DOIUrl":"10.1007/s10068-025-01834-x","url":null,"abstract":"<div><p>The iminosugars 1-deoxynojirimycin (1-DNJ) and 1-deoxymannojirimycin (1-DMJ) were produced by recombinant <i>Corynebacterium glutamicum</i> (<i>Cg</i>TYB) bearing the 1-DNJ-producing GabT1-Yktc1-GutB1 (TYB) gene cluster from <i>Bacillus velezensis</i> MBLB0692. The enhanced iminosugar biosynthesis in <i>Cg</i>TYB cultures increased both α-mannosidase inhibition (AMI) and α-glucosidase inhibition (AGI) activity. Individual cultures harboring GabT1, Yktc1, and GutB1 genes were found to be able to produce both 1-DNJ and 1-DMJ in mixed cultures of one pot analysis. This suggests that the genes necessary for epimerization and reduction are intrinsic to the cells rather than close to the 1-DNJ-producing cluster. Glucose was the preferred carbon source and a provision of 10 g/L glucose increased AGI and AMI to 69.8% and 70.1%, respectively. The 1 mM IPTG produced 55.0% AGI and 72.1% AMI, and 20% ethanolic permeabilization produced 62.8% AGI and 74.2% AMI. Batch fermentation increased iminosugar yields from 18.7 to 229.9 mg/L 1-DNJ, and 41.8 to 63.7 mg/mL 1-DMJ.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 10","pages":"2225 - 2235"},"PeriodicalIF":2.4,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143930053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Polygonum orientale L. flower addition on microbial community of Xiaoqu and volatile compounds of Huangjiu in Fangxian, China 加花对方县黄酒消曲及挥发性物质微生物群落的影响

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-14 DOI: 10.1007/s10068-025-01829-8

Xiaoqing Zhang, Ketao Jia, Jingjing Yi, Erhu Li

{"title":"Impact of Polygonum orientale L. flower addition on microbial community of Xiaoqu and volatile compounds of Huangjiu in Fangxian, China","authors":"Xiaoqing Zhang, Ketao Jia, Jingjing Yi, Erhu Li","doi":"10.1007/s10068-025-01829-8","DOIUrl":"10.1007/s10068-025-01829-8","url":null,"abstract":"<div><p>Fangxian Huangjiu is a Chinese rice wine fermented by the unique local starter Xiaoqu with the addition of <i>Polygonum orientale</i> L. (<i>P. orientale</i> L.) flower. This research aimed to elucidate the influence of <i>P. orientale</i> flower on the enzyme activity and microbial community of Fangxian Xiaoqu, and consequently on the physicochemical indicators and volatiles of Fangxian Huangjiu. The results revealed that the <i>P. orientale</i> flower significantly enhanced the acid protease activity and declined the α-amylase activity of Xiaoqu. Additionally, it improved microbial community diversity and the species of the dominant bacterial genus in Xiaoqu. For fermentation broth, the types of volatile substances have improved. Furthermore, Spearman correlation analysis revealed that <i>Pediococcus</i>, <i>Kosakonia, Saccharomycopsis, Mucor</i>, <i>Cyberlindnera</i>, and <i>Wickerhamomyces</i> were closely related to the synthesis of volatiles. These findings clarify the role of <i>P. orientale</i> flower and provide the practical basis for the future production of Fangxian Xiaoqu.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 9","pages":"1969 - 1980"},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flavor biotransformation of “Uiseong” garlic during the fermentation process by lactic acid bacteria 乳酸菌对“义成”大蒜发酵过程中风味的生物转化

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-14 DOI: 10.1007/s10068-025-01820-3

Tae-Eun Kwon, Sukyung Sung, Augustine Yonghwi Kim, Byung-Hoo Lee

{"title":"Flavor biotransformation of “Uiseong” garlic during the fermentation process by lactic acid bacteria","authors":"Tae-Eun Kwon, Sukyung Sung, Augustine Yonghwi Kim, Byung-Hoo Lee","doi":"10.1007/s10068-025-01820-3","DOIUrl":"10.1007/s10068-025-01820-3","url":null,"abstract":"<div><p>This study investigates the biotransformation of Uiseong garlic, a South Korean variety renowned for its distinct sulfur compounds, by lactic acid bacteria (LAB) during kimchi fermentation. Using GC–MS, 26 volatile compounds, including 3-vinyl-1,2-dithiocyclohex-4-ene and 3-vinyl-1,2-dithiocyclohex-5-ene, were identified in garlic extracts. Four LAB strains active in early-stage kimchi fermentation degraded primary sulfur compounds and produced unique metabolites, such as pyrazine and allyl methyl disulfide. These biotransformed compounds reduced garlic’s pungency while enhancing savory and umami flavors, creating a balanced and complex sensory profile. Strain-specific differences and fermentation conditions, especially temperature, significantly influenced flavor development. The findings underscore Uiseong garlic’s pivotal role in flavor modulation and its potential for consistent quality in commercial kimchi production. This research can be applied to flavor transformation mechanisms and supports precision fermentation strategies to optimize sensory profiles and meet consumer preferences.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 9","pages":"2005 - 2010"},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ginsenoside Rg5 inhibits the proliferation of HeLa cell through cell cycle pathway 人参皂苷Rg5通过细胞周期途径抑制HeLa细胞增殖

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-14 DOI: 10.1007/s10068-025-01817-y

Qianwen Mi, Hang Sun, Heyu Wang, Qiuyang Li, Pei Yin, Qiannan Wang, Jian Tong, Shuang Liu, Yunfeng Bi, Lei Yu

{"title":"Ginsenoside Rg5 inhibits the proliferation of HeLa cell through cell cycle pathway","authors":"Qianwen Mi, Hang Sun, Heyu Wang, Qiuyang Li, Pei Yin, Qiannan Wang, Jian Tong, Shuang Liu, Yunfeng Bi, Lei Yu","doi":"10.1007/s10068-025-01817-y","DOIUrl":"10.1007/s10068-025-01817-y","url":null,"abstract":"<div><p>The issue of Cervical cancer has received considerable critical attention. It was the leading cause of death in female cancer patients. Ginsenoside Rg5 has been implicated in the growth of human cancer cells, but the lack of research to determine the influence mechanism has been a significant challenge for many years. In this study, ginsenoside Rg5 was used to treat HeLa cells, and RT-qPCR, Western Blotting and RNA-seq were used to analyze the differentially expressed genes in HeLa cells to study the preliminary mechanism of ginsenoside Rg5 on cervical cancer. The results of RT-qPCR and Western Blotting were in agreement with RNA-seq analysis, which showed a down-regulation of proteins in the cell cycle pathway. These results all indicate that the expression of Minichromosome Maintenance Complex Component 6 (MCM6), Cyclin A2 (CCNA2), Cyclin-dependent kinase 6 (CDK6) and Cell division cycle 6 (CDC6) in HeLa cells treated with ginsenoside Rg5 is significantly reduced, with MCM6 exhibiting the most significant inhibitory effect, making it a potential target for the treatment of cervical cancer.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 9","pages":"2011 - 2024"},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Water-soluble carotenoid: focused on natural carotenoid crocin 水溶性类胡萝卜素：重点研究天然类胡萝卜素藏红花素

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-12 DOI: 10.1007/s10068-025-01832-z

Yosub Lee, Chi Young Hwang, Eui-Sang Cho, Myung-Ji Seo

{"title":"Water-soluble carotenoid: focused on natural carotenoid crocin","authors":"Yosub Lee, Chi Young Hwang, Eui-Sang Cho, Myung-Ji Seo","doi":"10.1007/s10068-025-01832-z","DOIUrl":"10.1007/s10068-025-01832-z","url":null,"abstract":"<div><p>Carotenoids are natural isoprenoid compounds with diverse health benefits, widely used in food, cosmetics, and pharmaceuticals. However, low bioavailability and chemical instability limit their effect according to their fat-soluble property. Some strategies such as nanoencapsulation, emulsions, complexation, and glycosylation have been explored to enhance carotenoid bioavailability. In addition, there is growing interest in water-soluble carotenoids in nature. This review focuses on recent advancements in improving the water solubility of carotenoids, with special attention to naturally occurring water-soluble carotenoids like crocin. Research progress on the biosynthetic pathways of crocin derived from natural plants is summarized. In addition, heterologous production using genetic and metabolic engineering in plants and microorganisms is discussed, along with its potential applications in bio-industries. Finally, the promising pharmacological properties of crocin, including antioxidant, anti-inflammatory and anticancer effects, are presented. The sustainable production of water-soluble carotenoids through biological synthesis offers a potential for improved absorption and functionality.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 and Processing","pages":"1119 - 1138"},"PeriodicalIF":2.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Informatics-assisted proteomics revealing the anti-inflammatory effects of satsuma orange (Citrus unshiu) peel flavonoid extract in LPS-stimulated RAW 264.7 cells 信息学辅助蛋白质组学揭示了蜜桔皮类黄酮提取物对lps刺激的RAW 264.7细胞的抗炎作用

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2025-02-12 DOI: 10.1007/s10068-025-01830-1

Adhimoolam Karthikeyan, Hun Hwan Kim, Sureshbabu Anjana, Smirnova Elena, Mohammad Moniruzzaman, Senthil Kalaiselvi, Gon Sup Kim, Taesun Min

{"title":"Informatics-assisted proteomics revealing the anti-inflammatory effects of satsuma orange (Citrus unshiu) peel flavonoid extract in LPS-stimulated RAW 264.7 cells","authors":"Adhimoolam Karthikeyan, Hun Hwan Kim, Sureshbabu Anjana, Smirnova Elena, Mohammad Moniruzzaman, Senthil Kalaiselvi, Gon Sup Kim, Taesun Min","doi":"10.1007/s10068-025-01830-1","DOIUrl":"10.1007/s10068-025-01830-1","url":null,"abstract":"<div><p><i>Citrus unshiu</i> peel (CUP), rich in flavonoids, has been traditionally used for its health benefits. This study investigated the anti-inflammatory effects of CUP flavonoid extract (CUPFE) in lipopolysaccharide (LPS)-activated RAW 264.7 cells through proteomics analysis. CUPFE significantly reduced the inflammatory mediators and cytokines (nitric oxide, IL-6, and CCL-2) production. Quantitative proteomics analysis using LC–MS/MS identified 140 differentially expressed proteins between the CUPFE and LPS groups, with 86 proteins upregulated and 54 downregulated. Notably, CUPFE negatively regulated 56 proteins induced by LPS. Functional enrichment analysis using gene ontology and Kyoto Encyclopedia of Genes and Genomes revealed that most of these proteins are involved in signal transduction pathways (TNF-α, NF-κB, PI3K-Akt, mTOR, and MAPK) regulating inflammatory processes. Further analysis showed that CUPFE interferes these signaling pathways in a dose-dependent manner, counteracting the LPS-induced effects. Collectively, this study reveals CUPFE’s anti-inflammatory effects, laying basis for future research on treating inflammation-related conditions.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 and Processing","pages":"1207 - 1218"},"PeriodicalIF":2.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0