Food Science and Biotechnology最新文献_第4页

Effect of Ixeris dentata extract on anti-inflammatory by inhibition of Nf-kb and cytokine levels Ixeris dentata 提取物通过抑制 Nf-kb 和细胞因子水平对抗炎药物的影响

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-11 DOI: 10.1007/s10068-024-01654-5

Min Ho Kang, So Hee Kim, Jae Hoon Park, Suh Hee Yeom, Jung Eun Park, Jin Woo Kim

{"title":"Effect of Ixeris dentata extract on anti-inflammatory by inhibition of Nf-kb and cytokine levels","authors":"Min Ho Kang, So Hee Kim, Jae Hoon Park, Suh Hee Yeom, Jung Eun Park, Jin Woo Kim","doi":"10.1007/s10068-024-01654-5","DOIUrl":"10.1007/s10068-024-01654-5","url":null,"abstract":"<div><p>Chronic inflammation is persistent disease caused by unregulated activation of <i>Nf-kb</i> pathway and production of pro-inflammatory cytokines, induced by accumulation of reactive oxygen species above thresholds. The purpose of this study was to evaluate the anti-oxidant, anti-lipidemia, inhibition <i>Nf-kb</i> pathway, and reduction of pro-inflammatory cytokine activities of <i>Ixeris dentata</i> extract (IDE) to demonstrate its inhibitory ability against chronic inflammatory in RAW264.7. Polyphenol content, radical scavenging activity, and lipase activity inhibition of IDE were 9.2 ± 0.2 GAE mg/g dry matter, 84.7%, and 72.4%, respectively, showing high effects against anti-oxidant and lipolysis inhibitory. Furthermore, anti-inflammatory effects of IDE on LPS-induced RAW 264.7 were investigated, and expression of inflammatory genes such as <i>Cox-2</i>, <i>Inos</i>, <i>Tnf-α</i>, <i>Il-6</i>, <i>Nf-kb</i>, and <i>Il-1β</i> were decreased by 36.5%–83.4%. Studies have confirmed that IDE has excellent antioxidant, lipolysis inhibitory, and anti-inflammatory effects, and <i>Ixeris dentata</i> can be used as natural ingredients for food and medicine to prevent.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 1","pages":"227 - 236"},"PeriodicalIF":2.4,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142176184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of NET-2201 (Capsicum chinense L. cv.) on brown adipose tissue activation and white adipose tissue browning in high-fat-diet-induced obese mice NET-2201（辣椒素）对高脂饮食诱导的肥胖小鼠棕色脂肪组织活化和白色脂肪组织棕色化的影响

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-11 DOI: 10.1007/s10068-024-01692-z

Yoon-Young Han, Ha-Neul Jo, Bo-Mi Kim, Jae-Sun Lee, Ji-Min Kim, Dae-Ho Ryu, Dong-Hee Kim, Chan-Sung Park, Byoung-Cheorl Kang, Yong-Wook Lee

{"title":"Effects of NET-2201 (Capsicum chinense L. cv.) on brown adipose tissue activation and white adipose tissue browning in high-fat-diet-induced obese mice","authors":"Yoon-Young Han, Ha-Neul Jo, Bo-Mi Kim, Jae-Sun Lee, Ji-Min Kim, Dae-Ho Ryu, Dong-Hee Kim, Chan-Sung Park, Byoung-Cheorl Kang, Yong-Wook Lee","doi":"10.1007/s10068-024-01692-z","DOIUrl":"10.1007/s10068-024-01692-z","url":null,"abstract":"<div><p>The present study explored the anti-obesity effects of NET-2201 (<i>Capsicum chinense</i> L. cv.), a non-pungent cultivated variety of chili pepper, and its underlying molecular mechanism in high-fat-diet (HFD)-induced obese mice. Administration of 50 mg/kg NET-2201 significantly inhibited body weight (BW) gain and reduced adipose tissue weight in obese mice. NET-2201 caused improvement in the expression levels of genes associated with lipid metabolism in white adipose tissue (WAT) to near-normal levels. Furthermore, NET-2201 significantly increased peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and uncoupling protein 1 (UCP1) protein expressions in brown adipose tissue (BAT). Moreover, NET-2201 activated WAT browning by altering the expression levels of brown and beige adipocyte-selective genes, including UCP1, PGC-1α, and PR domain containing 16. Our results indicate that dietary NET-2201 mitigates BW gain by activating BAT and inducing WAT browning.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 3","pages":"769 - 780"},"PeriodicalIF":2.4,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142176183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transforming plant proteins into plant-based meat alternatives: challenges and future scope 将植物蛋白转化为植物肉类替代品：挑战与未来空间

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-10 DOI: 10.1007/s10068-024-01683-0

Priyanka Prajapati, Meenakshi Garg, Neha Singh, Rajni Chopra, Avneesh Mittal, Prabhjot K. Sabharwal

{"title":"Transforming plant proteins into plant-based meat alternatives: challenges and future scope","authors":"Priyanka Prajapati, Meenakshi Garg, Neha Singh, Rajni Chopra, Avneesh Mittal, Prabhjot K. Sabharwal","doi":"10.1007/s10068-024-01683-0","DOIUrl":"10.1007/s10068-024-01683-0","url":null,"abstract":"<div><p>The global transition towards sustainable living has led to a growing demand for innovative food products that enhance environmental sustainability. Traditional meat production is known for its high energy consumption and significant carbon emissions, necessitating alternative approaches. Plant-based meat (PBM) offers a promising solution to reduce the ecological footprint of animal agriculture. This paper examines various challenges in PBM development, including nutritional equivalence, industrial scalability, organoleptic properties, and digestibility. Addressing these challenges requires interdisciplinary collaboration to ensure consumer acceptance, regulatory compliance, and environmental stewardship. Advanced technologies like nanotechnology, fermentation, and enzymatic hydrolysis, along with automation and repurposing cattle farms, offer solutions to enhance PBM’s quality and production efficiency. By integrating these innovations, PBM has the potential to revolutionize the food industry, offering sustainable and nutritious alternatives that meet global dietary needs while significantly reducing environmental impact.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"33 15","pages":"3423 - 3443"},"PeriodicalIF":2.4,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142223293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonanoic acid and cholecystokinin induce beige adipogenesis 壬酸和胆囊收缩素诱导米色脂肪生成

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-10 DOI: 10.1007/s10068-024-01699-6

Hyun Ji Park, Ji-Sun Kim, Eun Ryung Kim, Man Bock Gu, Sung-Joon Lee

{"title":"Nonanoic acid and cholecystokinin induce beige adipogenesis","authors":"Hyun Ji Park, Ji-Sun Kim, Eun Ryung Kim, Man Bock Gu, Sung-Joon Lee","doi":"10.1007/s10068-024-01699-6","DOIUrl":"10.1007/s10068-024-01699-6","url":null,"abstract":"<div><p>Beige adipocytes, crucial for thermogenesis, offer a potential therapeutic strategy for obesity. This study investigated the anti-obesity effects of nonanoic acid (NoA), medium-chain fatty acids, and cholecystokinin-8 (CCK-8) on beige adipogenesis in C3H10T1/2 mesenchymal stem cells (C3H10T1/2 MSCs). We observed a significant increase in cholecystokinin B receptor expression in beige adipocytes compared to preadipocytes. The co-treatment with NoA and CCK-8 enhanced beige adipocyte differentiation and lipid accumulation. Moreover, the co-treatment with NoA and CCK-8 upregulated the mRNA expression of thermogenic genes and increased mitochondrial activity more effectively than individual treatment. Specifically, NoA and CCK-8 co-treatment also elevated the protein expression of uncoupling protein 1 and peroxisome proliferator-activated receptor-gamma coactivator-1 alpha. These findings suggest that the additive effect of NoA and CCK-8 promotes the beiging/browning of body fat in beige adipogenesis, potentially serving as an effective approach in the prevention and treatment of obesity and insulin resistance.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 3","pages":"709 - 720"},"PeriodicalIF":2.4,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142176187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of lycopene, polyphenols, antioxidant compounds, and activities in colored cherry tomato cultivars harvested in Korea 评估韩国收获的彩色樱桃番茄品种中的番茄红素、多酚、抗氧化化合物和活性

IF 2.9 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-09 DOI: 10.1007/s10068-024-01691-0

Minji Joung, Young-Jun Kim, Youngjae Shin

{"title":"Assessment of lycopene, polyphenols, antioxidant compounds, and activities in colored cherry tomato cultivars harvested in Korea","authors":"Minji Joung, Young-Jun Kim, Youngjae Shin","doi":"10.1007/s10068-024-01691-0","DOIUrl":"https://doi.org/10.1007/s10068-024-01691-0","url":null,"abstract":"<p>Recently, there has been increased interest in colored foods because their unique pigments in fruits and vegetables originate from phytochemicals with antioxidant, anticancer, and antibacterial properties. Consequently, various colored cherry tomatoes have been developed. This study analyzed the lycopene, ascorbic acid, polyphenol, and antioxidant content and activity of 12 cultivars of colored cherry tomatoes harvested in Korea. The red colored cherry tomato cultivars ‘DOTORI RED TY’, ‘KT RED TY’, and ‘BLACK JOY200’ showed significantly higher levels of lycopene, a major antioxidant compound in tomato. Total flavonoid analysis showed that ‘DOTORI RED TY’, ‘TY Item’, and ‘TY Sispen’ had significantly higher concentrations, and a similar trend was observed in total phenolics. The major polyphenols in cherry tomatoes were identified as chlorogenic acid, rutin, and (-)-epigallocatechin gallate, with ‘TY Sispen’ showing significantly higher contents of chlorogenic acid and rutin, while ‘DOTORI RED TY’ exhibited higher levels of (-)-epigallocatechin gallate.</p>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"385 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142176185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization and semi-continuous fermentation of gluco-oligosaccharide production with Weissella cibaria YRK005 用西伯利亚魏氏菌 YRK005 优化和半连续发酵生产葡聚寡糖

IF 2.9 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-09 DOI: 10.1007/s10068-024-01703-z

Sungyoon Kim, Jisun Park, Huijin Jeong, Young-Seo Park

{"title":"Optimization and semi-continuous fermentation of gluco-oligosaccharide production with Weissella cibaria YRK005","authors":"Sungyoon Kim, Jisun Park, Huijin Jeong, Young-Seo Park","doi":"10.1007/s10068-024-01703-z","DOIUrl":"https://doi.org/10.1007/s10068-024-01703-z","url":null,"abstract":"<p>In this study, we optimized gluco-oligosaccharide production using <i>Weissella cibaria</i> YRK005 through a semi-continuous fermentation. The Plackett–Burman design identified sucrose and maltose concentrations and fermentation temperature as key factors. Optimization using response surface methodology with a central composite design identified optimal conditions as 14.7% w/v sucrose, 13.5% w/v maltose, and 30 °C, predicting a relative peak area (RPA) of 115.6. Comparative analysis of the anaerobic and aerobic batch fermentation showed higher productivity under the aerobic conditions (25.5 RPA/h) than under the anaerobic conditions (23.7 RPA/h). The aerobic semi-continuous fermentation, with media replenishment every 7 h, achieved 39.2 RPA/h in one-cycle fermentation, exceeding the 27.2 RPA/h in two-cycle fermentation. These results highlight the importance of fermentation conditions in enhancing gluco-oligosaccharide production and suggests that the aerobic semi-continuous fermentation is a promising strategy for industrial applications to increase efficiency and reduce costs.</p>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"60 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142223292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational approaches to predict the toxicity of bioactive natural products: a mini review of methodologies 预测生物活性天然产品毒性的计算方法：方法论小评

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-09 DOI: 10.1007/s10068-024-01701-1

Kwanyong Choi, Ji Yeon Kim

引用次数: 0

Opportunities and challenges of foodborne polyphenols applied to anti-aging health foods 食源性多酚应用于抗衰老保健食品的机遇与挑战

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-07 DOI: 10.1007/s10068-024-01686-x

Hong Zhuang, Xiaoliang Zhang, Sijia Wu, Pang Yong, Haiyang Yan

{"title":"Opportunities and challenges of foodborne polyphenols applied to anti-aging health foods","authors":"Hong Zhuang, Xiaoliang Zhang, Sijia Wu, Pang Yong, Haiyang Yan","doi":"10.1007/s10068-024-01686-x","DOIUrl":"10.1007/s10068-024-01686-x","url":null,"abstract":"<p>With the increasing proportion of the global aging population, aging mechanisms and anti-aging strategies become hot topics. Nonetheless, the safety of non-natural anti-aging active molecule and the changes in physiological function that occur during aging have not been clarified. There is therefore a need to develop safer pharmaceutical interventions for anti-aging. Numerous types of research have shown that food-derived biomolecules are of great interest due to their unique contribution to anti-aging safety issues and the prevention of degenerative diseases. Among these, polyphenolic organic compounds are widely used in anti-aging research for their ability to mitigate the physiological functional changes that occur during aging. The mechanisms include the free radical theory, immune aging theory, cellular autophagy theory, epigenetic modification theory, gut microbial effects on aging theory, telomere shortening theory, etc. This review elucidates the mechanisms underlying the anti-aging effects of polyphenols found in food-derived bioactive molecules, while also addressing the challenges associated with anti-aging pharmaceuticals. The review concludes by offering insights into the current landscape of anti-aging active molecule research, aiming to serve as a valuable resource for further scholarly inquiry.</p>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"33 15","pages":"3445 - 3461"},"PeriodicalIF":2.4,"publicationDate":"2024-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142176189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification, characterization, and anti-inflammatory activity of a lipocalin-like protein cloned from Oenanthe javanica 从 Oenanthe javanica 克隆的一种脂钙蛋白样蛋白的鉴定、表征和抗炎活性

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-03 DOI: 10.1007/s10068-024-01700-2

Hyun Soo Kim, Jeong Won Ahn, Jung Youl Park, Seong Soo Joo

{"title":"Identification, characterization, and anti-inflammatory activity of a lipocalin-like protein cloned from Oenanthe javanica","authors":"Hyun Soo Kim, Jeong Won Ahn, Jung Youl Park, Seong Soo Joo","doi":"10.1007/s10068-024-01700-2","DOIUrl":"10.1007/s10068-024-01700-2","url":null,"abstract":"<div><p>This study investigated the anti-inflammatory effects of OJlipo1, a lipocalin-like protein derived from <i>Oenanthe javanica</i>. Through cloning and expressing OJlipo1 in <i>E. coli</i>, and subsequent rigorous characterization including amino acid analysis and mass spectrometry, its potential against inflammation was evaluated. Studies on lipopolysaccharide-stimulated RAW 264.7 cells highlighted its capability to suppress nitric oxide synthase and cyclooxygenase-2 expression, as well as its interference with nuclear factor kappa B and mitogen-activated protein kinase pathways, which are essential for toll-like receptor 4 (TLR4) signaling. Utilizing TAK242, a TLR4 pathway inhibitor, reinforced OJlipo1’s specific targeting mechanism. These findings underscore OJlipo1’s significant anti-inflammatory potential, aligning with the traditional uses of <i>O. javanica</i>, and suggest new therapeutic avenues, especially for diseases associated with TLR4 dysregulation. This validates the traditional application of <i>O. javanica</i> in inflammation and positions OJlipo1 as a promising therapeutic candidate, enriching our understanding of its molecular underpinnings and therapeutic prospects.</p></div>","PeriodicalId":566,"journal":{"name":"Food Science and Biotechnology","volume":"34 3","pages":"721 - 731"},"PeriodicalIF":2.4,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142176191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensorial flavor characteristics and volatile Maillard reaction products of Tenebrio molitor mealworm based-reaction flavors with beef broth-like flavor 基于黄粉虫（Tenebrio molitor）的具有牛肉汤风味的反应香精的感官风味特征和挥发性 Maillard 反应产物

IF 2.4 3区农林科学

Food Science and Biotechnology Pub Date : 2024-09-02 DOI: 10.1007/s10068-024-01681-2

Hyeyoung Park, In Hee Cho

引用次数: 0