Minerva Pediatrics最新文献_第7页

Association between IL-1 single nucleotide polymorphisms and susceptibility to juvenile idiopathic arthritis: a systematic review and meta-analysis. IL-1单核苷酸多态性与幼年特发性关节炎易感性之间的关系：系统综述和荟萃分析。

IF 1

Minerva Pediatrics Pub Date : 2024-11-05 DOI: 10.23736/S2724-5276.24.07696-1

Aysan Moeinafshar, Raha Zamani, Nima Rezaei

{"title":"Association between IL-1 single nucleotide polymorphisms and susceptibility to juvenile idiopathic arthritis: a systematic review and meta-analysis.","authors":"Aysan Moeinafshar, Raha Zamani, Nima Rezaei","doi":"10.23736/S2724-5276.24.07696-1","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07696-1","url":null,"abstract":"Introduction: Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases of childhood and presents with various clinical phenotypes. A multifactorial and complex interaction of genetic and environmental factors are responsible for JIA, of which the proinflammatory cytokine genes are of particular research interest. This meta-analysis investigates the association between IL-1A and IL-1B gene polymorphisms and susceptibility to JIA.Evidence acquisition: A total of eight studies, involving 1633 patients and 2309 controls were included, and a meta-analysis was performed on the association between IL1A -889 C/T, IL1B -511 C/T, and IL1B +3954 C/T, and susceptibility to JIA.Evidence synthesis: There was no significant association between the presence of IL1A -889 C/T, IL1B -511 C/T, and IL1B +3954 C/T polymorphisms and JIA, under any genetic model or in any ethnicity subgroups.Conclusions: Results of this study suggest that these three IL-1 variants do not increase the susceptibility to JIA. However, the limited number of studies and the considerable level of heterogeneity must be taken into account before interpretation.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing pediatric outpatient efficiency: evaluating fine-tuned length of stay management during influenza peaks. 优化儿科门诊效率：评估流感高峰期住院时间的微调管理。

IF 1

Minerva Pediatrics Pub Date : 2024-10-07 DOI: 10.23736/S2724-5276.24.07707-3

Yu Sun, Hongmei Zhu, Hui Wang, Hong Sun, Xuefeng Zhang

引用次数: 0

Perceived impact of pediatric palliative care: caregiver's perspective. 儿科姑息关怀的影响感知：照护者的视角。

IF 1

Minerva Pediatrics Pub Date : 2024-10-07 DOI: 10.23736/S2724-5276.24.07593-1

Alexandra L Ribeiro, Madalena V Hafe, Joana Torgal, Inês F Azevedo, Paula M Guerra

{"title":"Perceived impact of pediatric palliative care: caregiver's perspective.","authors":"Alexandra L Ribeiro, Madalena V Hafe, Joana Torgal, Inês F Azevedo, Paula M Guerra","doi":"10.23736/S2724-5276.24.07593-1","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07593-1","url":null,"abstract":"Background: Caregivers of children with complex chronic diseases (CCD) or life-limiting conditions (LLC) experience heightened strain. Understanding their concerns is essential for effective support, particularly in pediatric palliative care (PPC) where compassionate support is crucial. Amid substantial growth in PPC services in Portugal, assessing the effectiveness of care in addressing these concerns and adapting to the evolving needs of parents is imperative. The aim of this study was to perceive the impact of PPC from the caregivers' perspective.Methods: Participants consisted of children with CDD or LLC and their caregivers followed by the PPC team. Institutionalized children were excluded. Our mixed-methods study involved analyzing sociodemographic characteristics and assessing caregiver and child well-being using quantitative data and explored caregiver concerns and the impact of PPC through qualitative data obtained from semi-structured interviews.Results: We included 43 children and caregivers. Caregivers (90.6% mothers; mean age 40) often experience fatigue (90.7%) although they rarely feel exhausted (67.4%). Sleep disturbances (58.1%) are the children's most frequent perceived symptom. Seven categories emerge from caregivers' concerns. Among the five categories arising from caregivers' perceived impact of PPC integration, 95.3% prioritize enhanced contact with healthcare professionals. Increased support to facilitate caregiver rest and early referral emerges as primary suggestions for improving PPC.Conclusions: The PPC appears to be effective in alleviating parents' primary concerns, highlighting the crucial importance of early referral. Implementing strategies to provide respite for caregivers and closer monitoring of these children becomes a priority to improve the quality of life for this inherently intertwined dyad, the child-family unit.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The identification of a novel hemizygous interleukin 2 receptor subunit gamma (IL2RG) mutation following vaccination in a pediatric patient with X-linked severe combined immunodeficiency. 在一名 X 连锁重症联合免疫缺陷儿患者的疫苗接种后，发现了一种新型半杂合体白细胞介素 2 受体亚基 gamma (IL2RG) 突变。

IF 1

Minerva Pediatrics Pub Date : 2024-10-07 DOI: 10.23736/S2724-5276.24.07664-X

Xiaojuan Luo, Ke Cao, Yan Zhang, Xiaoning Mao, Xueyan Chen

引用次数: 0

The contribution of physical exercise to leukemia and lymphoma in children: a scoping review. 体育锻炼对儿童白血病和淋巴瘤的影响：范围界定综述。

IF 1

Minerva Pediatrics Pub Date : 2024-10-07 DOI: 10.23736/S2724-5276.24.07548-7

Marco Monticone, Barbara Rocca, Fulvio Dal Farra

{"title":"The contribution of physical exercise to leukemia and lymphoma in children: a scoping review.","authors":"Marco Monticone, Barbara Rocca, Fulvio Dal Farra","doi":"10.23736/S2724-5276.24.07548-7","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07548-7","url":null,"abstract":"Introduction: The overall contribution of physical exercise on the management of disabling consequences of leukemia and lymphoma in children is missing. The aim of this scoping review (ScoR) was to systematically collect, map and present the current research evidence concerning studies reporting data on physical exercise among children with leukemia and lymphoma.Evidence acquisition: This ScoR was performed by adopting recommendations of the 2020 version of the \"Joanna Briggs Institute Methodological Guidance\", along with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews. PubMed, Scopus, and the Central (Cochrane) were searched up to December 2023. Original studies were included, and results were presented numerically and thematically.Evidence synthesis: One hundred twelve articles were identified through the search; 14 studies met the inclusion criteria. Publications have increased over the years. Most of the studies were conducted in Western countries. 11 articles (79%) owned to primary research (seven RCTs, and four observational studies), and 3 studies (21%) were systematic reviews. The overall sample size was of 293 individuals. 1 study included a mixed population of leukemias and lymphomas, while the others included only children with leukemia. The features of physical exercise were well described, including details on duration of treatment, frequency of exercises sessions, and duration of sittings.Conclusions: The studies indicated physical exercise as a contributor to the improvement of motor abilities and quality of life. More studies including outcome measures that assess disability are recommended. More evidence on the impact of physical exercise in children with lymphoma is needed.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prospective, randomized, double-blind trial to validate the efficacy of an oral herbal gel on pain in the newborn during minor diagnostic-therapeutic procedures. 前瞻性、随机、双盲试验，验证口服草药凝胶对新生儿在小型诊断治疗过程中疼痛的疗效。

IF 1

Minerva Pediatrics Pub Date : 2024-10-07 DOI: 10.23736/S2724-5276.24.07556-6

Federico Mecarini, Giorgio Bracaglia

{"title":"Prospective, randomized, double-blind trial to validate the efficacy of an oral herbal gel on pain in the newborn during minor diagnostic-therapeutic procedures.","authors":"Federico Mecarini, Giorgio Bracaglia","doi":"10.23736/S2724-5276.24.07556-6","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07556-6","url":null,"abstract":"Background: Term and preterm infants are frequently exposed to painful procedures and stimuli during hospitalization in the Neonatal Intensive Care Unit (NICU). Pain is widely recognized to cause short- and long-term effects in the newborn. In recent years there has been a growing medical interest and a strong demand from parents for phytotherapeutic drugs, but literature data are limited, and excellent methodological studies are necessary to evaluate the importance of phytotherapy in the neonatal period.Methods: We evaluated the use of an oral phytotherapeutic gel based on chamomile, angelica and oats in the management of full term and preterm infant pain caused by minor diagnostic or therapeutic procedures. We enrolled full term infants (>37 weeks gestational age [GA]) and preterm infants with higher GA than 28 weeks, weighing more than 1000 grams. Assessed painful procedures were minor diagnostic or therapeutic ones. Newborns were double-blind randomized into two groups (A and B) to orally receive the phytotherapeutic gel (solution A) and a gel of the same consistency and aroma (solution B) before the painful procedure.Results: The group of newborns to whom solution A had been administered showed significantly lower scores in the Pain Scale (P<0.01) during painful procedure. This figure indicates that the herbal medicine has been effective in reducing pain experience in the population of examined newborns.Conclusions: To the best of our literature research, our work is the first scientific study highlighting the possibility of preventive beneficial effects of phytotherapeutic drugs on pain control.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteitis of the radius after bacillus Calmette-Guèrin vaccination in international adopted children. 国际收养儿童接种卡介苗后出现桡骨骨膜炎。

IF 1

Minerva Pediatrics Pub Date : 2024-10-01 Epub Date: 2024-05-27 DOI: 10.23736/S2724-5276.24.07609-2

Marco Denina, Ada Papalia, Carlo Scolfaro, Erika Silvestro, Federica Mignone, Antonio Curtoni, Anna M Barbui, Silvia Garazzino

引用次数: 0

Assessment of the perception of nasal breathing using Visual Analog Scale in children with newly diagnosed allergic rhinitis: the link with asthma. 使用视觉模拟量表评估新确诊过敏性鼻炎患儿的鼻呼吸感：与哮喘的联系。

IF 1

Minerva Pediatrics Pub Date : 2024-10-01 Epub Date: 2024-01-30 DOI: 10.23736/S2724-5276.24.07534-7

Maria A Tosca, Irene Schiavetti, Vincenzo Meleca, Matteo Naso, Chiara Trincianti, Giorgio Ciprandi

引用次数: 0

Adolescent suicide: a major mental health issue in pediatric care. 青少年自杀：儿科护理中的一个主要心理健康问题。

IF 1

Minerva Pediatrics Pub Date : 2024-10-01 Epub Date: 2023-11-10 DOI: 10.23736/S2724-5276.23.06682-X

Afroditi E Zartaloudi

引用次数: 0

Changes in adolescent mental health during the Covid pandemic. 科维德病毒大流行期间青少年心理健康的变化。

IF 1

Minerva Pediatrics Pub Date : 2024-10-01 Epub Date: 2021-04-23 DOI: 10.23736/S2724-5276.21.06178-4

Çilem Bilginer, Selman Yildirim, Berire Çekin Yilmaz, Ercüment Beyhun, Serkan Karadeniz

{"title":"Changes in adolescent mental health during the Covid pandemic.","authors":"Çilem Bilginer, Selman Yildirim, Berire Çekin Yilmaz, Ercüment Beyhun, Serkan Karadeniz","doi":"10.23736/S2724-5276.21.06178-4","DOIUrl":"10.23736/S2724-5276.21.06178-4","url":null,"abstract":"Background: Previous pandemics around the world have shown that negative emotions are intensified in individuals when restrictions are imposed on human daily life activities. This study aims to draw attention to the pandemic-specific factors that might be associated with the severity of depression, anxiety, and COVID-19 phobia of high school students.Methods: A total of 1431 high school students aged 14 to 18 years were invited to participate in this study using online survey forms. They were asked to fill out a questionnaire about themselves and the changes in their lives during the pandemic. They completed the COVID-19 Phobia Scale (C19P-S) and the Revised Children's Anxiety and Depression Scale (RCADS).Results: Findings showed that being a girl is an increased risk factor for anxiety, depression, and COVID-19 phobia. In addition, following the official daily COVID-19 data and having a healthcare professional in the building of residence are significant risk factors for COVID-19 phobia. Having a psychiatric disorder, having a chronic disease, losing anyone due to COVID-19 infection, undergoing a COVID-19 diagnostic test, and meeting friends in person are increased risk factors for anxiety or depression during the pandemic.Conclusions: Changes in adolescents' lives caused by the COVID-19 pandemic are negatively affecting their mental health. Studies are needed to maintain the mental well-being of adolescents under the conditions of this pandemic.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"652-659"},"PeriodicalIF":1.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9919141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0