Minerva PediatricsPub Date : 2025-05-08DOI: 10.23736/S2724-5276.25.07871-1
Valentina Pucinischi, Giovanni DI Nardo, Enrico Felici, Maurizio Mennini
{"title":"Pediatrics and artificial intelligence: shaping the future of child healthcare.","authors":"Valentina Pucinischi, Giovanni DI Nardo, Enrico Felici, Maurizio Mennini","doi":"10.23736/S2724-5276.25.07871-1","DOIUrl":"https://doi.org/10.23736/S2724-5276.25.07871-1","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High risk of malignancy in neonates with cystic pulmonary abnormalities and no antenatal findings.","authors":"Alessia Bertolino, Riccardo Guanà, Elisa Zambaiti, Alessia Cerrina, Alessandro Pane, Salvatore Garofalo, Fabrizio Gennari, Federico Scottoni","doi":"10.23736/S2724-5276.24.07552-9","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07552-9","url":null,"abstract":"<p><strong>Background: </strong>The postnatal management of pulmonary malformations is still controversial, especially in terms of indication and timing for surgery. Despite being rare, neonatal lung tumors should be included in the differential diagnosis in case of neonatal pulmonary abnormalities. The aim of this study is to evaluate if the absence of antenatal findings should be considered a risk factor for malignancy in patients with lung abnormalities at postnatal imaging.</p><p><strong>Methods: </strong>The medical records of neonatal patients undergone surgery for pulmonary abnormalities in our hospital, over a period of 5 years (2017-2021), were retrospectively reviewed. Histological diagnosis and presence of findings at prenatal scans were recorded. A literature review on this topic was also conducted.</p><p><strong>Results: </strong>Histological diagnosis was pulmonary primary malignancy in 3 cases (2 pulmonary blastomas, 1 fetal lung interstitial tumor), the remaining 20 were diagnosed as pulmonary malformations. We recorded that 100% of our patients affected by lung tumor had no abnormalities at prenatal scans. Three papers reporting similar results were found in literature.</p><p><strong>Conclusions: </strong>Differential diagnosis among neonatal cystic abnormalities is challenging. When a cystic lung lesion is present in infants who had no abnormalities at standard antenatal scans, a malignancy should be considered.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01Epub Date: 2024-10-07DOI: 10.23736/S2724-5276.24.07648-1
Chunling Zhang, Jianmei Tian
{"title":"The impact of empowerment-based fine-grained nursing model on nursing outcomes, compliance, and sleep quality of pediatric pneumonia patients.","authors":"Chunling Zhang, Jianmei Tian","doi":"10.23736/S2724-5276.24.07648-1","DOIUrl":"10.23736/S2724-5276.24.07648-1","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"186-188"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01Epub Date: 2025-01-16DOI: 10.23736/S2724-5276.24.07803-0
Giorgio Ciprandi, Attilio Varricchio
{"title":"Survey on the attitude of Italian pediatricians concerning the use of the topical nasal therapy.","authors":"Giorgio Ciprandi, Attilio Varricchio","doi":"10.23736/S2724-5276.24.07803-0","DOIUrl":"10.23736/S2724-5276.24.07803-0","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"184-186"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01DOI: 10.23736/S2724-5276.21.06320-5
Aslihan Köse Çetinkaya, Mehmet Büyüktiryaki, Fatma N Sari, Erbu Yarci, Evrim Alyamaç Dizdar, Cüneyt Tayman, Şerife S Oğuz
{"title":"Higher mean platelet volume is associated with pulmonary hemorrhage in very low birth weight infants.","authors":"Aslihan Köse Çetinkaya, Mehmet Büyüktiryaki, Fatma N Sari, Erbu Yarci, Evrim Alyamaç Dizdar, Cüneyt Tayman, Şerife S Oğuz","doi":"10.23736/S2724-5276.21.06320-5","DOIUrl":"https://doi.org/10.23736/S2724-5276.21.06320-5","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to determine whether there was an association between platelet parameters and the presence of pulmonary hemorrhage (PH) in very low birth weight infants.</p><p><strong>Methods: </strong>Fifty preterm infants who developed PH with gestational age ≤30 weeks and birth weight ≤1500 g were analyzed retrospectively. The infants with PH were matched for gestational age and birthweight with infants without PH, who served as control group. Groups were compared in terms of demographic, clinical characteristics and for the platelet parameters. Red cell distribution width to platelet ratio (RPR) and platelet mass were also calculated.</p><p><strong>Results: </strong>A total of 150 premature infants were analyzed in the study, including 50 infants with PH and 100 controls. In terms of platelet parameters, the PH group had significantly lower platelet count, mean platelet volume (MPV) and RPR (P=0.025, P<0.001, P=0.003; respectively). Multiple logistic regression analysis showed that respiratory distress syndrome (OR: 8.69; 95%[CI]: 2.71- 27.7; P<0.001) and MPV>8.1fL (OR: 2.60; 95% CI: 1.11-6.06; P=0.019) were independent risk factors for PH.</p><p><strong>Conclusions: </strong>Our data indicated that PH was associated with the presence of RDS and higher MPV in preterm infants.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":"77 2","pages":"143-147"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01Epub Date: 2023-02-14DOI: 10.23736/S2724-5276.23.07089-1
Renaud Vialet, Jean-Luc Dettori, Johanna Pirello, Marjolaine Oger, Alexandre Lacoste
{"title":"Neonatal ethanol exposure from sanitizers in isolettes: a bench study.","authors":"Renaud Vialet, Jean-Luc Dettori, Johanna Pirello, Marjolaine Oger, Alexandre Lacoste","doi":"10.23736/S2724-5276.23.07089-1","DOIUrl":"10.23736/S2724-5276.23.07089-1","url":null,"abstract":"<p><strong>Background: </strong>Ethanol-based hand sanitizer (EBHS) is used repeatedly in neonatology. Inadequately dried hands can increase ambient ethanol concentrations in air, especially in a small, enclosed space as isolette. We sought to better document the potential exposure to alcohol vapors on a newborn placed in an isolette, by mimicking common neonatal situations.</p><p><strong>Methods: </strong>EBHS were rubbed on hands for 10 or 30 seconds, before inserting hands in the isolette of 1 or 2 experimenters for 6 minutes. Ethanol concentrations were measured every 30 seconds with photoionization detector.</p><p><strong>Results: </strong>Twenty-six trials were made, with 286 measurements. With four hands, the concentration peak was in mean about 700 (±900) ppm and with two hands about 300 ppm. With 10-second rubbing time, the concentrations peak was in mean about 850 ppm, and with 30-second rubbing time, mean concentrations were about 100 pm. When respecting normal use (rubbing time 30 seconds), observed ethanol concentrations were low, always below 200 ppm with 2 or 4 hands.</p><p><strong>Conclusions: </strong>Concentrations of ethanol are very high when drying of EHBS is incomplete. The exposure is of short duration, but ethanol inhalation may be negatively experienced by the child during procedures, especially since they may be frequent and repeated. To minimize the child's exposure to ethanol, we suggest the hands should be completely dried before being inserted into the isolette.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"117-120"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10709971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01Epub Date: 2024-10-07DOI: 10.23736/S2724-5276.24.07611-0
Giorgia Gaiba, Patrizia Lugari, Roberto Tedeschi
{"title":"Educational therapy for caregivers of children with obstetric brachial plexus palsy: a scoping review.","authors":"Giorgia Gaiba, Patrizia Lugari, Roberto Tedeschi","doi":"10.23736/S2724-5276.24.07611-0","DOIUrl":"10.23736/S2724-5276.24.07611-0","url":null,"abstract":"<p><strong>Introduction: </strong>Obstetric brachial plexus palsy (OBPP), a condition resulting from the stretching of nerve structures in an infant's upper limb during childbirth, necessitates early physiotherapy intervention. Continuation of rehabilitative activities at home is critical for optimal recovery, highlighting the need for effective caregiver education in managing this condition. This scoping review seeks to consolidate and examine existing research on physiotherapy treatments for OBPP, with a specific focus on the educational support provided to caregivers. The ultimate objective is to develop an informative booklet for caregivers, offering essential guidance for home management of affected children.</p><p><strong>Evidence acquisition: </strong>A comprehensive search was conducted across PubMed, Cochrane Library, Scopus and PEDro from May to October 2023, with no restrictions on study design, evidence level, publication date, geography, or language. Articles were selected based on preset eligibility criteria.</p><p><strong>Evidence synthesis: </strong>The search yielded 13 relevant studies, encompassing a diverse range of research designs including reviews, systematic reviews, case reports, controlled trials, and a retrospective study.</p><p><strong>Conclusions: </strong>This review underscores the necessity of a personalized rehabilitation approach in treating OBPP, with parental involvement being crucial. It also identifies a gap in research regarding the long-term effectiveness of these interventions, suggesting the need for further studies to ascertain optimal treatment modalities.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"178-183"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01Epub Date: 2024-10-07DOI: 10.23736/S2724-5276.24.07701-2
Huijie Xu, Yue Wang, Lu Zhou, Lin Lin, Fei Lin, Lifen Wang
{"title":"Evidence-based nursing in oxygen-driven nebulized inhalation treatment in children with asthmatic bronchitis.","authors":"Huijie Xu, Yue Wang, Lu Zhou, Lin Lin, Fei Lin, Lifen Wang","doi":"10.23736/S2724-5276.24.07701-2","DOIUrl":"10.23736/S2724-5276.24.07701-2","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"189-191"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva PediatricsPub Date : 2025-04-01Epub Date: 2024-12-09DOI: 10.23736/S2724-5276.24.07616-X
Patrik Konopásek, Vít Neuman, Barbora Piteková, Jakub Zieg, Jan Lebl
{"title":"Investigation of glucosuria in children.","authors":"Patrik Konopásek, Vít Neuman, Barbora Piteková, Jakub Zieg, Jan Lebl","doi":"10.23736/S2724-5276.24.07616-X","DOIUrl":"10.23736/S2724-5276.24.07616-X","url":null,"abstract":"<p><p>Previous reports provided recommendations for familial renal glucosuria diagnosis without complex view on differential diagnosis of glucosuria. The aim of this review was to provide an overview of the causes of glucosuria and to create an evidence-based diagnostic approach for children with glucosuria. We searched the current literature with a focus to identify the possible etiology of glucosuria, gaining insight into the pathophysiology of glucosuria. Urinary glucose is completely reabsorbed in the proximal tubule of kidneys. It only appears in the urine if the plasma glucose concentration exceeds the renal threshold for glucose or in the case of insufficient renal glucose reabsorption. The proteins that provide glucose reabsorption are SGLT2 and SGLT1 - sodium-dependent co-transporters that transport glucose from the lumen into epithelial cells - and GLUT2 - a passive transporter providing facilitative glucose transport from epithelial cells to plasma. Renal glucose reabsorption is affected in case of acquired or inherited complex dysfunction of proximal tubule called Fanconi Syndrome or due to pathogenic variants of genes encoding glucose transporters. Prior to diagnosing any of these, diabetes mellitus must be excluded together with other conditions leading to hyperglycemia. In conclusion, glucosuria is always an abnormal finding. The review provides a simple evidence-based diagnostic approach to navigate the differential diagnosis of glucosuria.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"168-177"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complicated pneumonia requiring invasive procedures in children in the post-COVID period: monocentric experience.","authors":"Chiara Costantini, Riccardo Guanà, Elisa Zambaiti, Elena Stanton, Luca Lonati, Steffi Shilly, Fabrizio Gennari, Federico Scottoni","doi":"10.23736/S2724-5276.25.07722-5","DOIUrl":"https://doi.org/10.23736/S2724-5276.25.07722-5","url":null,"abstract":"<p><strong>Background: </strong>The Severe Acute Respiratory Syndrome virus (SARS-CoV-2) had a great impact in the worldwide population. Because of personal protective equipment (PPE), children have not been exposed to the commonly circulating respiratory viruses, with an effect on pneumonia disease spreading. The aim of our study was to evaluate the different distribution of invasive procedures for complicated pneumonia in pre, intra and post pandemic period.</p><p><strong>Methods: </strong>We conducted a retrospective analysis in children who underwent invasive procedures for complicated pneumonia, focusing on the winter season. Three periods were identified: pre-SARS-CoV-2 (14 months), pandemic (11 months) and post-SARS-CoV-2 (5 months). The invasive procedures considered were thoracentesis, chest tube placement, and video-assisted thoracoscopic surgery (VATS).</p><p><strong>Results: </strong>A total of 67 children were admitted to our Institution for complicated pneumonia between November 2017 and March 2023 with a mean of 2.6, 1 and 4.4 per months respectively, in pre-pandemic and post-SARS-CoV-2. A chest tube was placed in 24% of pre-pandemic patients, 9% of pandemic and 50% of post-pandemic (P=0.002). Fifty percent of post-pandemic patients required VATS (P=0.014). Chest CT scans demonstrated necrotizing pneumonia with higher frequency in post-SARS-CoV-2 period (P=0.031).</p><p><strong>Conclusions: </strong>PPE preserved from SARS-CoV-2 but influenced the spread of other pathogens. We reported an increasing number of complicated pneumonias requiring surgery and of necrotizing pneumonia in the post-pandemic period.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}