Minerva Pediatrics最新文献_第2页

Neonatal ethanol exposure from sanitizers in isolettes: a bench study. 新生儿从等离子体消毒剂中摄入乙醇：一项工作台研究。

IF 1

Minerva Pediatrics Pub Date : 2025-04-01 Epub Date: 2023-02-14 DOI: 10.23736/S2724-5276.23.07089-1

Renaud Vialet, Jean-Luc Dettori, Johanna Pirello, Marjolaine Oger, Alexandre Lacoste

{"title":"Neonatal ethanol exposure from sanitizers in isolettes: a bench study.","authors":"Renaud Vialet, Jean-Luc Dettori, Johanna Pirello, Marjolaine Oger, Alexandre Lacoste","doi":"10.23736/S2724-5276.23.07089-1","DOIUrl":"10.23736/S2724-5276.23.07089-1","url":null,"abstract":"Background: Ethanol-based hand sanitizer (EBHS) is used repeatedly in neonatology. Inadequately dried hands can increase ambient ethanol concentrations in air, especially in a small, enclosed space as isolette. We sought to better document the potential exposure to alcohol vapors on a newborn placed in an isolette, by mimicking common neonatal situations.Methods: EBHS were rubbed on hands for 10 or 30 seconds, before inserting hands in the isolette of 1 or 2 experimenters for 6 minutes. Ethanol concentrations were measured every 30 seconds with photoionization detector.Results: Twenty-six trials were made, with 286 measurements. With four hands, the concentration peak was in mean about 700 (±900) ppm and with two hands about 300 ppm. With 10-second rubbing time, the concentrations peak was in mean about 850 ppm, and with 30-second rubbing time, mean concentrations were about 100 pm. When respecting normal use (rubbing time 30 seconds), observed ethanol concentrations were low, always below 200 ppm with 2 or 4 hands.Conclusions: Concentrations of ethanol are very high when drying of EHBS is incomplete. The exposure is of short duration, but ethanol inhalation may be negatively experienced by the child during procedures, especially since they may be frequent and repeated. To minimize the child's exposure to ethanol, we suggest the hands should be completely dried before being inserted into the isolette.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"117-120"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10709971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Educational therapy for caregivers of children with obstetric brachial plexus palsy: a scoping review. 产科臂丛神经麻痹患儿看护者的教育疗法：范围界定综述。

IF 1

Minerva Pediatrics Pub Date : 2025-04-01 Epub Date: 2024-10-07 DOI: 10.23736/S2724-5276.24.07611-0

Giorgia Gaiba, Patrizia Lugari, Roberto Tedeschi

{"title":"Educational therapy for caregivers of children with obstetric brachial plexus palsy: a scoping review.","authors":"Giorgia Gaiba, Patrizia Lugari, Roberto Tedeschi","doi":"10.23736/S2724-5276.24.07611-0","DOIUrl":"10.23736/S2724-5276.24.07611-0","url":null,"abstract":"Introduction: Obstetric brachial plexus palsy (OBPP), a condition resulting from the stretching of nerve structures in an infant's upper limb during childbirth, necessitates early physiotherapy intervention. Continuation of rehabilitative activities at home is critical for optimal recovery, highlighting the need for effective caregiver education in managing this condition. This scoping review seeks to consolidate and examine existing research on physiotherapy treatments for OBPP, with a specific focus on the educational support provided to caregivers. The ultimate objective is to develop an informative booklet for caregivers, offering essential guidance for home management of affected children.Evidence acquisition: A comprehensive search was conducted across PubMed, Cochrane Library, Scopus and PEDro from May to October 2023, with no restrictions on study design, evidence level, publication date, geography, or language. Articles were selected based on preset eligibility criteria.Evidence synthesis: The search yielded 13 relevant studies, encompassing a diverse range of research designs including reviews, systematic reviews, case reports, controlled trials, and a retrospective study.Conclusions: This review underscores the necessity of a personalized rehabilitation approach in treating OBPP, with parental involvement being crucial. It also identifies a gap in research regarding the long-term effectiveness of these interventions, suggesting the need for further studies to ascertain optimal treatment modalities.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"178-183"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence-based nursing in oxygen-driven nebulized inhalation treatment in children with asthmatic bronchitis. 对哮喘性支气管炎患儿进行氧气驱动雾化吸入治疗的循证护理。

IF 1

Minerva Pediatrics Pub Date : 2025-04-01 Epub Date: 2024-10-07 DOI: 10.23736/S2724-5276.24.07701-2

Huijie Xu, Yue Wang, Lu Zhou, Lin Lin, Fei Lin, Lifen Wang

引用次数: 0

Investigation of glucosuria in children. 儿童高血糖的调查。

IF 1

Minerva Pediatrics Pub Date : 2025-04-01 Epub Date: 2024-12-09 DOI: 10.23736/S2724-5276.24.07616-X

Patrik Konopásek, Vít Neuman, Barbora Piteková, Jakub Zieg, Jan Lebl

{"title":"Investigation of glucosuria in children.","authors":"Patrik Konopásek, Vít Neuman, Barbora Piteková, Jakub Zieg, Jan Lebl","doi":"10.23736/S2724-5276.24.07616-X","DOIUrl":"10.23736/S2724-5276.24.07616-X","url":null,"abstract":"Previous reports provided recommendations for familial renal glucosuria diagnosis without complex view on differential diagnosis of glucosuria. The aim of this review was to provide an overview of the causes of glucosuria and to create an evidence-based diagnostic approach for children with glucosuria. We searched the current literature with a focus to identify the possible etiology of glucosuria, gaining insight into the pathophysiology of glucosuria. Urinary glucose is completely reabsorbed in the proximal tubule of kidneys. It only appears in the urine if the plasma glucose concentration exceeds the renal threshold for glucose or in the case of insufficient renal glucose reabsorption. The proteins that provide glucose reabsorption are SGLT2 and SGLT1 - sodium-dependent co-transporters that transport glucose from the lumen into epithelial cells - and GLUT2 - a passive transporter providing facilitative glucose transport from epithelial cells to plasma. Renal glucose reabsorption is affected in case of acquired or inherited complex dysfunction of proximal tubule called Fanconi Syndrome or due to pathogenic variants of genes encoding glucose transporters. Prior to diagnosing any of these, diabetes mellitus must be excluded together with other conditions leading to hyperglycemia. In conclusion, glucosuria is always an abnormal finding. The review provides a simple evidence-based diagnostic approach to navigate the differential diagnosis of glucosuria.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"168-177"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complicated pneumonia requiring invasive procedures in children in the post-COVID period: monocentric experience. 后covid时期儿童需要侵入性手术的复杂肺炎：单中心经验。

IF 1

Minerva Pediatrics Pub Date : 2025-03-25 DOI: 10.23736/S2724-5276.25.07722-5

Chiara Costantini, Riccardo Guanà, Elisa Zambaiti, Elena Stanton, Luca Lonati, Steffi Shilly, Fabrizio Gennari, Federico Scottoni

{"title":"Complicated pneumonia requiring invasive procedures in children in the post-COVID period: monocentric experience.","authors":"Chiara Costantini, Riccardo Guanà, Elisa Zambaiti, Elena Stanton, Luca Lonati, Steffi Shilly, Fabrizio Gennari, Federico Scottoni","doi":"10.23736/S2724-5276.25.07722-5","DOIUrl":"https://doi.org/10.23736/S2724-5276.25.07722-5","url":null,"abstract":"Background: The Severe Acute Respiratory Syndrome virus (SARS-CoV-2) had a great impact in the worldwide population. Because of personal protective equipment (PPE), children have not been exposed to the commonly circulating respiratory viruses, with an effect on pneumonia disease spreading. The aim of our study was to evaluate the different distribution of invasive procedures for complicated pneumonia in pre, intra and post pandemic period.Methods: We conducted a retrospective analysis in children who underwent invasive procedures for complicated pneumonia, focusing on the winter season. Three periods were identified: pre-SARS-CoV-2 (14 months), pandemic (11 months) and post-SARS-CoV-2 (5 months). The invasive procedures considered were thoracentesis, chest tube placement, and video-assisted thoracoscopic surgery (VATS).Results: A total of 67 children were admitted to our Institution for complicated pneumonia between November 2017 and March 2023 with a mean of 2.6, 1 and 4.4 per months respectively, in pre-pandemic and post-SARS-CoV-2. A chest tube was placed in 24% of pre-pandemic patients, 9% of pandemic and 50% of post-pandemic (P=0.002). Fifty percent of post-pandemic patients required VATS (P=0.014). Chest CT scans demonstrated necrotizing pneumonia with higher frequency in post-SARS-CoV-2 period (P=0.031).Conclusions: PPE preserved from SARS-CoV-2 but influenced the spread of other pathogens. We reported an increasing number of complicated pneumonias requiring surgery and of necrotizing pneumonia in the post-pandemic period.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intranasal dexmedetomidine for procedural sedation in infants: a retrospective study. 鼻内右美托咪定用于婴儿手术镇静：一项回顾性研究。

IF 1

Minerva Pediatrics Pub Date : 2025-03-25 DOI: 10.23736/S2724-5276.25.07768-7

Gianluca Dini, Federica Celi, Maria G Santini, Carla M Semeraro

{"title":"Intranasal dexmedetomidine for procedural sedation in infants: a retrospective study.","authors":"Gianluca Dini, Federica Celi, Maria G Santini, Carla M Semeraro","doi":"10.23736/S2724-5276.25.07768-7","DOIUrl":"https://doi.org/10.23736/S2724-5276.25.07768-7","url":null,"abstract":"Background: Infants undergoing magnetic resonance imaging (MRI) often require pharmacological sedation. Dexmedetomidine is an alpha-2 receptor agonist that is frequently used to sedate children and infants, because the neonatologist can easily adjust sedation depth, the patient maintains spontaneous breathing, and awakens rapidly afterwards. The present study evaluates whether dexmedetomidine could safely be used as the sole sedative for preterm and term-born infants less than 80 weeks' postmenstrual age undergoing diagnostic procedures.Methods: We performed a retrospective monocentric analysis of 50 preterm and term-born infants (<80 weeks' postmenstrual age) who were sedated with dexmedetomidine for a brain MRI from October 2019 to March 2024.Results: Successful imaging was achieved in all cases. The median dexmedetomidine loading dose was 2.75 μg/kg (2-4 μg/kg). Bradycardia was observed in four out of 50 patients (8%) and none of them required atropine.Conclusions: These results suggest that dexmedetomidine can be safely used for procedural sedation in the high-risk cohort of preterm and term-born infants less than 80 weeks' postmenstrual age.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetal alcohol spectrum disorders prevention: is it necessary? 预防胎儿酒精谱系障碍：有必要吗？

IF 1

Minerva Pediatrics Pub Date : 2025-03-25 DOI: 10.23736/S2724-5276.25.07839-5

Patrizia Balbinot, Gianni Testino

引用次数: 0

Point-of-care ultrasound recognition of massive thymic hyperplasia. 大量胸腺增生的即时超声识别。

IF 1

Minerva Pediatrics Pub Date : 2025-03-13 DOI: 10.23736/S2724-5276.25.07821-8

Marco Denina, Giulia Tosoni, Irene Raffaldi, Angelo G Delmonaco, Antonio Pizzol, Matilde Piglione, Claudia Bondone

引用次数: 0

The role of combining anti-reflux and anti-drooling surgery in neurologically impaired children with chronic lung aspiration. 联合抗反流和抗流口水手术在慢性肺误吸神经功能受损儿童中的作用。

IF 1

Minerva Pediatrics Pub Date : 2025-02-18 DOI: 10.23736/S2724-5276.24.07669-9

Angelo Zarfati, Sonia Battaglia, Daniela Camanni, Ottavio Adorisio, Francesco DE Peppo

{"title":"The role of combining anti-reflux and anti-drooling surgery in neurologically impaired children with chronic lung aspiration.","authors":"Angelo Zarfati, Sonia Battaglia, Daniela Camanni, Ottavio Adorisio, Francesco DE Peppo","doi":"10.23736/S2724-5276.24.07669-9","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07669-9","url":null,"abstract":"Background: Hospitalizations for children with neurological impairments (NI) are frequently caused by chronic lung aspiration (CLA). Gastroesophageal reflux disease (GERD) and posterior drooling are two of the causes of CLA. Combination of anti-reflux procedure, i.e. Nissen fundoplication (NF), and anti-drooling surgery, i.e. subtotal functional sialoadenectomy (SFS), could effectively address both components of CLA. This study presents outcomes of the combined surgical treatment, especially focusing on long-term results. The aim of this article is to present our experience using a combination of NF and SFS as treatments for CLA caused by refractory GERD and drooling in pediatric patients with NI.Methods: Retrospective analysis of consecutive patients treated in our pediatric tertiary center (period: 2012-20). Inclusion criteria: NI patients with CLA, simultaneous refractory GERD and drooling, minimal follow-up ≥12 months.Results: Seventeen patients included (12 males): all patients had dysphagia and fifteen (88%) had vomiting/regurgitation. Four patients (24%) had ≤1 aspiration pneumonia/year, while 13 (76%) had recurring episodes (≥2 per year). The median age at surgery was 8.2 years old (0.8-18.5). Three patients (18%) had early major complications (Clavien-Dindo ≥IIIa). After surgery, study population showed a significant decrease in vomiting/regurgitation (P=0.0004), posterior drooling (P=0.0039), and mean episodes of pneumonia/year (P=0.0009). One patient (6%) needed re-do fundoplication for GERD recurrence. One patient (6%) had tracheostomy. No surgery related mortality was recorded.Conclusions: The combination of NF and SFS offers a chance to face up to chronic pulmonary aspiration, proving to effectively treating both GER and posterior drooling, with an acceptably low complication rate.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of nocturnal enuresis in children. 儿童夜间遗尿的处理。

IF 1

Minerva Pediatrics Pub Date : 2025-02-18 DOI: 10.23736/S2724-5276.25.07812-7

Ignazio Cammisa, Margherita Zona, Pietro Ferrara

{"title":"Management of nocturnal enuresis in children.","authors":"Ignazio Cammisa, Margherita Zona, Pietro Ferrara","doi":"10.23736/S2724-5276.25.07812-7","DOIUrl":"https://doi.org/10.23736/S2724-5276.25.07812-7","url":null,"abstract":"Introduction: Nocturnal enuresis is defined as involuntary urination during sleep in children, particularly those aged 5 years or older. Treatment approaches include both pharmacological and non-pharmacological methods, with choices depending on the type and severity of nocturnal enuresis, as well as family dynamics. This review evaluates current knowledge on nocturnal enuresis treatment in children.Evidence acquisition: A systematic review of studies published from 2000 to 2024 was conducted, assessing both pharmacological and non-pharmacological interventions.Evidence synthesis: Nocturnal enuresis in children has been treated with various pharmacological and non-pharmacological interventions. Non-pharmacological therapies for nocturnal enuresis offer effective, low-risk options for managing this common pediatric condition, particularly when used in combination. Enuresis alarm therapy, considered the first-line treatment, has demonstrated success rates between 50% and 70%. On the other hand, bladder training, pelvic floor retraining and dietary modification play a supportive role in nocturnal enuresis management. Pharmacological interventions mainly include desmopressin and anticholinergics. Combination therapies, particularly desmopressin and anticholinergics, have demonstrated superior efficacy and faster results compared to monotherapy.Conclusions: A variety of pharmacological and non-pharmacological treatments have been developed to manage nocturnal enuresis and improve the quality of life for affected children. The primary goal for healthcare providers is to tailor a treatment plan to each child, taking into consideration the individual needs of the child and their family.","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0