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Clinical profiles of acute arterial ischemic neonatal stroke. 急性动脉缺血性新生儿脑卒中的临床特点。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 Epub Date: 2023-05-31 DOI: 10.23736/S2724-5276.23.07301-9
Mario Mastrangelo, Rossella Bove, Giacomina Ricciardi, Laura Giordo, Paola Papoff, Emanuela Turco, Maria Lucente, Francesco Pisani
{"title":"Clinical profiles of acute arterial ischemic neonatal stroke.","authors":"Mario Mastrangelo, Rossella Bove, Giacomina Ricciardi, Laura Giordo, Paola Papoff, Emanuela Turco, Maria Lucente, Francesco Pisani","doi":"10.23736/S2724-5276.23.07301-9","DOIUrl":"10.23736/S2724-5276.23.07301-9","url":null,"abstract":"<p><strong>Introduction: </strong>Perinatal stroke includes a heterogeneous group of early focal neurological injuries affecting subsequent brain development, often resulting in motor sequelae, symptomatic epilepsies, and cognitive, language and behavioral impairment. The incidence of perinatal stroke is about 1/3500 live birth.</p><p><strong>Evidence acquisition: </strong>A PubMed and SCOPUS search strategy included the entries \"neonatal ischemic stroke\" OR \"perinatal ischemic stroke\" and the age of the filter under 18 years and January 2000-August 2022.</p><p><strong>Evidence synthesis: </strong>The cumulative literature analysis highlighted 3880 published patients (from 98 articles) with stroke, mainly presenting with clinical or electro-graphical seizures (2083 patients). The mean age at presentation was 2,5±2,4 days (data available for 1182 patients). Stroke occurred in the first week of life in 1164 newborns. The mainly involved ischemic areas were within the territories of the middle cerebral artery (1403 patients). Predisposing risk factors included fetal/newborn factors (1908 patients), dystocial birth (759 patients), maternal (678 patients), and placental factors (63 patients). No thrombolysis and/or endovascular treatments were performed, while data about other pharmacological treatments were restricted to a single article. The death occurred in 29 newborns. Motor, neurocognitive and language impairment were cumulatively reported in 875 patients. Epileptic seizures during the follow-up were reported in 238 cases.</p><p><strong>Conclusions: </strong>The literature analysis highlighted that every term newborn presenting with acute neurological signs and symptoms during the first week of life should always be considered for the identification of an ischemic stroke.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"767-776"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9546356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new multicomponent nasal spray for managing children with recurrent upper respiratory infections. 用于治疗儿童反复上呼吸道感染的新型多成分鼻腔喷雾剂。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 Epub Date: 2024-09-16 DOI: 10.23736/S2724-5276.24.07615-8
Ignazio LA Mantia, Giovanna Stilo, Giuliano Messina, Attilio Varricchio, Giorgio Ciprandi
{"title":"A new multicomponent nasal spray for managing children with recurrent upper respiratory infections.","authors":"Ignazio LA Mantia, Giovanna Stilo, Giuliano Messina, Attilio Varricchio, Giorgio Ciprandi","doi":"10.23736/S2724-5276.24.07615-8","DOIUrl":"10.23736/S2724-5276.24.07615-8","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"806-808"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malnutrition and sarcopenia in children with cancer. 癌症儿童的营养不良和肌肉疏松症。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 Epub Date: 2024-06-11 DOI: 10.23736/S2724-5276.24.07608-0
Antonio Ruggiero
{"title":"Malnutrition and sarcopenia in children with cancer.","authors":"Antonio Ruggiero","doi":"10.23736/S2724-5276.24.07608-0","DOIUrl":"10.23736/S2724-5276.24.07608-0","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"719-721"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141302154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The pediatrician's point of view on a new "emollient plus". 儿科医生对新型 "润肤剂添加剂 "的看法。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 Epub Date: 2024-06-21 DOI: 10.23736/S2724-5276.24.07636-5
Gian L Marseglia, Amelia Licari, Riccardo Castagnoli, Maria A Tosca, Giorgio Ciprandi
{"title":"The pediatrician's point of view on a new \"emollient plus\".","authors":"Gian L Marseglia, Amelia Licari, Riccardo Castagnoli, Maria A Tosca, Giorgio Ciprandi","doi":"10.23736/S2724-5276.24.07636-5","DOIUrl":"10.23736/S2724-5276.24.07636-5","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"803-804"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical study of pit and fissure sealant combined with light-cured flowable resin in prevention of dental caries in children. 坑和裂隙封闭剂结合光固化流动树脂预防儿童龋齿的临床研究。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI: 10.23736/S2724-5276.24.07639-0
Baican Wang, Yongyu Lou
{"title":"Clinical study of pit and fissure sealant combined with light-cured flowable resin in prevention of dental caries in children.","authors":"Baican Wang, Yongyu Lou","doi":"10.23736/S2724-5276.24.07639-0","DOIUrl":"10.23736/S2724-5276.24.07639-0","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"808-809"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphine versus hydromorphone in pediatrics: a narrative review of latest indications and optimal use in neonates and children. 吗啡与氢吗啡酮在儿科：新生儿和儿童最新适应症和最佳使用的叙述性回顾。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 Epub Date: 2023-09-06 DOI: 10.23736/S2724-5276.23.07275-0
Sarah Spénard, Marie-Elaine Metras, Charles Gélinas, Vibhuti Shah, Marie-Joëlle Doré-Bergeron, Kathryn Dekoven, Marc-Antoine Marquis, Evelyne D Trottier, Céline Thibault, Niina Kleiber
{"title":"Morphine versus hydromorphone in pediatrics: a narrative review of latest indications and optimal use in neonates and children.","authors":"Sarah Spénard, Marie-Elaine Metras, Charles Gélinas, Vibhuti Shah, Marie-Joëlle Doré-Bergeron, Kathryn Dekoven, Marc-Antoine Marquis, Evelyne D Trottier, Céline Thibault, Niina Kleiber","doi":"10.23736/S2724-5276.23.07275-0","DOIUrl":"10.23736/S2724-5276.23.07275-0","url":null,"abstract":"<p><p>The management of pain in pediatrics is multimodal and includes non-pharmacologic and pharmacologic approaches. Opioids, and particularly morphine and hydromorphone, are frequently used to treat moderate-to-severe pain. The goals of this review are to describe the pharmacological characteristics of both drugs, to cover the latest evidence of their respective indications, and to promote their safe use in pediatrics. Morphine is the most studied opioid in children and is known to be safe and effective. Morphine and hydromorphone can be used to manage acute pain and are usually avoided when treating chronic non-cancer pain. Current evidence suggests that both opioids have a similar efficacy and adverse effect profile. Hydromorphone has not been studied in neonates but in some centers, it has been used instead of morphine for certain patients. In palliative care, the use of opioids is often indicated and their benefits extend beyond analgesia; indications include treatment of central neuropathic pain in children with severe neurologic impairment and treatment of respiratory distress in the imminently dying patients. The longstanding belief that the use of well-titrated opioids hastens death should be abandoned as robust evidence has shown the opposite. With the current opioid crisis, a responsible use of opioids should be promoted, including limiting the opioid prescription to the patient's anticipated needs, optimizing a multimodal analgesic plan including the use of non-pharmacological measures and non-opioid medications, and providing information on safe storage and disposal to patients and families. More data is needed to better guide the use of morphine and hydromorphone in children.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":"777-789"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10163357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using artificial intelligence to determine best time to switch intravenous to oral antibiotics in pediatrics. 使用人工智能来确定儿科静脉注射到口服抗生素的最佳时间。
IF 1
Minerva Pediatrics Pub Date : 2024-12-01 DOI: 10.23736/S2724-5276.24.07719-X
Muhammad A Chughtai, Shandana Younas
{"title":"Using artificial intelligence to determine best time to switch intravenous to oral antibiotics in pediatrics.","authors":"Muhammad A Chughtai, Shandana Younas","doi":"10.23736/S2724-5276.24.07719-X","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07719-X","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":"76 6","pages":"810-811"},"PeriodicalIF":1.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Italian version of the Coma Recovery Scale for Pediatrics. 意大利语版儿科昏迷恢复量表。
IF 1
Minerva Pediatrics Pub Date : 2024-11-21 DOI: 10.23736/S2724-5276.24.07575-X
Monica Beschi, Sandra Strazzer, Katia Colombo, Cristina Reverberi
{"title":"The Italian version of the Coma Recovery Scale for Pediatrics.","authors":"Monica Beschi, Sandra Strazzer, Katia Colombo, Cristina Reverberi","doi":"10.23736/S2724-5276.24.07575-X","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07575-X","url":null,"abstract":"<p><strong>Background: </strong>The Coma Recovery Scale for Pediatrics (CRS-P) is a modified version of the Coma Recovery Scale-Revised (CRS-R). This CRS-P looks at behavioral responses and diagnoses Coma, Vegetative State, MCS and E-MCS in pediatric age. It is an ordinal scale consisting of 29 items divided into 6 subscales. The CRS-R is a gold standard for the assessment of adults with disorders of consciousness (DOC) and is also recommended for children, following the American Guidelines.</p><p><strong>Methods: </strong>The CRS-P was translated and culturally adapted into Italian by two independent translators in order to test an adapted Italian version on Italian children.</p><p><strong>Results: </strong>We found conceptual, semantic and content correspondence between the original version and the preliminary version of the CRS-P in Italian.</p><p><strong>Conclusions: </strong>The Italian CRS-P version can be tested on Italian children and then validated.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy and safety of laparoscopic pyeloplasty via abdominal approach for the treatment of ureteropelvic junction obstruction in children. 经腹腔镜肾盂成形术治疗儿童输尿管盆腔交界处梗阻的有效性和安全性。
IF 1
Minerva Pediatrics Pub Date : 2024-11-07 DOI: 10.23736/S2724-5276.24.07712-7
Zedong Bian, Yong Zhi, Geng Xiong, Yi Tan, Ming Liu
{"title":"The efficacy and safety of laparoscopic pyeloplasty via abdominal approach for the treatment of ureteropelvic junction obstruction in children.","authors":"Zedong Bian, Yong Zhi, Geng Xiong, Yi Tan, Ming Liu","doi":"10.23736/S2724-5276.24.07712-7","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07712-7","url":null,"abstract":"","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between IL-1 single nucleotide polymorphisms and susceptibility to juvenile idiopathic arthritis: a systematic review and meta-analysis. IL-1单核苷酸多态性与幼年特发性关节炎易感性之间的关系：系统综述和荟萃分析。
IF 1
Minerva Pediatrics Pub Date : 2024-11-05 DOI: 10.23736/S2724-5276.24.07696-1
Aysan Moeinafshar, Raha Zamani, Nima Rezaei
{"title":"Association between IL-1 single nucleotide polymorphisms and susceptibility to juvenile idiopathic arthritis: a systematic review and meta-analysis.","authors":"Aysan Moeinafshar, Raha Zamani, Nima Rezaei","doi":"10.23736/S2724-5276.24.07696-1","DOIUrl":"https://doi.org/10.23736/S2724-5276.24.07696-1","url":null,"abstract":"<p><strong>Introduction: </strong>Juvenile idiopathic arthritis (JIA) is one of the most common chronic diseases of childhood and presents with various clinical phenotypes. A multifactorial and complex interaction of genetic and environmental factors are responsible for JIA, of which the proinflammatory cytokine genes are of particular research interest. This meta-analysis investigates the association between IL-1A and IL-1B gene polymorphisms and susceptibility to JIA.</p><p><strong>Evidence acquisition: </strong>A total of eight studies, involving 1633 patients and 2309 controls were included, and a meta-analysis was performed on the association between IL1A -889 C/T, IL1B -511 C/T, and IL1B +3954 C/T, and susceptibility to JIA.</p><p><strong>Evidence synthesis: </strong>There was no significant association between the presence of IL1A -889 C/T, IL1B -511 C/T, and IL1B +3954 C/T polymorphisms and JIA, under any genetic model or in any ethnicity subgroups.</p><p><strong>Conclusions: </strong>Results of this study suggest that these three IL-1 variants do not increase the susceptibility to JIA. However, the limited number of studies and the considerable level of heterogeneity must be taken into account before interpretation.</p>","PeriodicalId":56337,"journal":{"name":"Minerva Pediatrics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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