Korean Journal of Pain最新文献_第3页

Retraction: Comparison of the efficacy of genicular nerve phenol neurolysis and radiofrequency ablation for pain management in patients with knee osteoarthritis. 撤回：膝关节骨性关节炎患者膝神经苯酚神经溶解术和射频消融术止痛疗效比较。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 Epub Date: 2024-10-23 DOI: 10.3344/kjp.23220r

Gokhan Yildiz, Gevher Rabia Genc Perdecioglu, Damla Yuruk, Ezgi Can, Omer Taylan Akkaya

引用次数: 0

Ultrasound-guided pain management: pros, cons, and benefits for the Philippines. 超声引导下的疼痛治疗：利弊及对菲律宾的益处。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 Epub Date: 2024-11-01 DOI: 10.3344/kjp.24246

John Patrick C Toledo

引用次数: 0

Temporal therapy utilizing exosomes derived from M2 macrophages demonstrates enhanced efficacy in alleviating neuropathic pain in diabetic rats. 利用来源于M2巨噬细胞的外泌体进行颞叶治疗，可以增强糖尿病大鼠神经性疼痛的缓解效果。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 Epub Date: 2024-12-23 DOI: 10.3344/kjp.24244

Wei Wei, Jun Fang, Baozhong Yang, Chenlong Cui, Jiacheng Wei, Yating Xue

{"title":"Temporal therapy utilizing exosomes derived from M2 macrophages demonstrates enhanced efficacy in alleviating neuropathic pain in diabetic rats.","authors":"Wei Wei, Jun Fang, Baozhong Yang, Chenlong Cui, Jiacheng Wei, Yating Xue","doi":"10.3344/kjp.24244","DOIUrl":"10.3344/kjp.24244","url":null,"abstract":"Background: Diabetic pain patients have increased pain at night. Exosomes can relieve neuropathic pain. This study aimed to investigate the efficacy of exosome administration at different time points in relieving diabetic neuropathic pain (DNP) in rats.Methods: M2 macrophages from bone marrow were induced in mice and exosomes were extracted. A diabetic rat model was induced using streptozotocin, with the mechanical withdrawal threshold (MWT) of the rats being measured at ≤ 80% of the basal value after 14 days, indicating successful construction of the DNP rat model. Exosomes were administered on three consecutive days at ZT0 (zeitgeber time) and ZT12. Parameters including blood glucose levels, body weight, MWT, and thermal withdrawal latency (TWL) were assessed in the rats. The lumbar spinal cord of rats was examined on days 21 and 28 to measure inflammatory factors and observe the expression of M1 and M2 microglia. Furthermore, microglia were exposed to lipopolysaccharide (LPS) and LPS + exosomes in a controlled in vitro setting to assess alterations in microglia phenotype involving the NF-kB p65 and IKBα inflammatory signaling pathways.Results: The findings revealed that administration of exosomes during the rat resting period at ZT12 resulted in increased MWT and TWL, as well as a shift in microglia polarization towards the M2 phenotype. In vitro analysis indicated that exosomes influenced microglia polarization and suppressed the phosphorylation of NF-kB p65 and IKBα.Conclusions: Temporal therapy with exosomes effectively reduces pain in DNP rats by polarizing microglia and affecting NF-kB p65 and IKBα signaling pathways.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"14-28"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum: The role of the peripheral chemokine, CCL3, in hyperalgesia following peripheral nerve injury in the rat. 勘误：外周趋化因子CCL3在大鼠外周神经损伤后痛觉过敏中的作用。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 DOI: 10.3344/kjp.050c

Joong Woo Leem, Hyun Ju Lee, Taick Sang Nam, Duck Mi Yoon

引用次数: 0

Characterizing pain in Parkinson's disease: types, predictors, and management implications. 帕金森病患者疼痛的特征：类型、预测因素和管理意义。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 DOI: 10.3344/kjp.24245

Ceren Alis, Derya Selcuk Demirelli, Elvin Ay, Gencer Genc

{"title":"Characterizing pain in Parkinson's disease: types, predictors, and management implications.","authors":"Ceren Alis, Derya Selcuk Demirelli, Elvin Ay, Gencer Genc","doi":"10.3344/kjp.24245","DOIUrl":"10.3344/kjp.24245","url":null,"abstract":"Background: Pain impacts quality of life (QoL) in Parkinson's disease (PD) patients, yet it is often overlooked. This study aims to comprehensively evaluate pain in PD, particularly focusing on differences between neuropathic pain (NP) and other types.Methods: We conducted a cross-sectional study involving PD patients, assessing the prevalence and characteristics of pain. Various scales were employed to evaluate anxiety, depression, and QoL. We investigated associations between pain, demographic, and clinical variables to determine predictors and pain-related factors. Additionally, factors related to NP were explored.Results: During the study period, a total of 109 patients were examined. Sixteen patients were excluded due to various reasons. The final analysis included 93 patients (34 females and 59 males). Pain was reported by 80.6% of PD patients, with no significant demographic or clinical differences between those with and without pain. However, longer disease duration predicted NP, and musculoskeletal pain was more prevalent in females. Anxiety was common in patients with central parkinsonian pain (CPP). Patients taking amantadine reported less radicular/ neuropathic pain (RNP), suggesting a therapeutic role.Conclusions: Our findings underscore the high prevalence of pain in PD and its impact on QoL. NP appears to be associated with disease progression, while sex-specific differences highlight the need for personalized pain management strategies. The association between anxiety and CPP emphasizes the importance of addressing psychological factors in PD pain management. Further research on amantadine's benefits in reducing RNP is warranted, emphasizing the importance of tailored pain management strategies for PD patients.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"38 1","pages":"43-50"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of central sensitization-related symptoms on subacromial steroid injection outcomes in patients with subacromial impingement syndrome: an observational study. 中枢致敏相关症状对肩峰下撞击综合征患者肩峰下类固醇注射结果的影响：一项观察性研究

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 Epub Date: 2024-12-23 DOI: 10.3344/kjp.24290

Feyza Nur Yücel, Semiha Özgüç, Yeliz Bahar-Özdemir, Emre Ata

{"title":"The impact of central sensitization-related symptoms on subacromial steroid injection outcomes in patients with subacromial impingement syndrome: an observational study.","authors":"Feyza Nur Yücel, Semiha Özgüç, Yeliz Bahar-Özdemir, Emre Ata","doi":"10.3344/kjp.24290","DOIUrl":"10.3344/kjp.24290","url":null,"abstract":"Background: Evidence indicates that central sensitization (CS) plays a role in subacromial impingement syndrome (SIS). Reduced treatment response has been associated with pretreatment pain sensitization features, such as CSrelated symptoms.Methods: Patients who received subacromial steroid injection were evaluated before the injection, at the first and third months. CS-related symptoms were investigated through the central sensitization inventory (CSI), and pain hypersensitivity was investigated by pressure pain threshold (PPT). Patients were evaluated using the visual analog scale (VAS), Quick Disabilities of the Arm, Shoulder, and Hand, Hospital Anxiety and Depression Scale, and Short Form-36.Results: With the injection, all participants had a significant reduction in shoulder pain (P < 0.05). In all follow-ups, VAS values did not differ significantly between the groups, and patients with CSI ≥ 40 had higher levels of disability, anxiety, depression, and worse quality of life before treatment (P < 0.05). Post-injection disability decreased significantly in the CS group and reached similar levels in both groups at the third month (P > 0.05). Although both groups' PPT values were comparable pre-treatment and at the third month, the CS group's affected shoulder showed a notable PPT decline at the first month (P < 0.05).Conclusions: Pre-treatment CS-related symptoms had no effect on SIS patients' responsiveness to steroid injections.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"29-42"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The actual duration of spinal cord stimulator use in patients with complex regional pain syndrome: a Korean nationwide cohort study. 复杂局部疼痛综合征患者使用脊髓刺激器的实际持续时间：一项韩国全国队列研究。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 Epub Date: 2024-12-23 DOI: 10.3344/kjp.24209

In-Ae Song, Joon Hee Lee, Woong Ki Han, Francis Sahngun Nahm

{"title":"The actual duration of spinal cord stimulator use in patients with complex regional pain syndrome: a Korean nationwide cohort study.","authors":"In-Ae Song, Joon Hee Lee, Woong Ki Han, Francis Sahngun Nahm","doi":"10.3344/kjp.24209","DOIUrl":"10.3344/kjp.24209","url":null,"abstract":"Background: Spinal cord stimulators (SCSs) are used to reduce pain and improve quality of life in patients with complex regional pain syndrome (CRPS). However, many patients opt for device removal after SCS implantation due to diminished effect or complications. There is limited research on the actual duration of SCS use in CRPS patients, and no nationwide population-based studies exist. This study aimed to estimate the real-world duration of SCS use in CRPS patients and examine the influencing factors on the duration of SCS use by analyzing the National Healthcare Insurance Database.Methods: Adult patients (age ≥ 18) with CRPS who underwent permanent SCS implantation between 2014 and 2021 were included. The authors analyzed the median duration of SCS implantation and evaluated the impacts of age, sex, hospital type, and insurance type.Results: Of 408 potential patients, 373 patients were included. The median duration of SCS use was 4.4 (95% confidence interval [CI]: 4.0-4.8) years. Male patients retained SCSs longer than female patients (4.7 vs . 4.0 years, P = 0.014), and veterans' healthcare beneficiaries showed the longest duration of SCS use (median 6.9 [95% CI: 4.6-7.8] years). Age and hospital type did not affect the duration of SCS use (P = 0.381 and P = 0.122, respectively).Conclusions: The median SCS use duration in CRPS patients was 4.4 years. Considering the high cost and invasiveness of SCS, patients should be informed about the expected duration of SCS use, alongside potential risks and benefits.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"51-57"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Data sharing and research integrity: lessons from a recent retraction. 数据共享和研究诚信：来自最近撤稿的教训。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 DOI: 10.3344/kjp.24391

Francis Sahngun Nahm

引用次数: 0

Validation of the Korean version of defense and veterans pain rating scale for assessment of postoperative pain: a prospective observational cohort study. 韩国版国防和退伍军人疼痛评定量表用于评估术后疼痛的有效性：一项前瞻性观察队列研究。

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 Epub Date: 2024-12-30 DOI: 10.3344/kjp.24346

Seungeun Choi, Taeyup Kim, Hae Kyeong Yoo, Sang-Youn Park, Soo-Hyuk Yoon, Ho-Jin Lee

{"title":"Validation of the Korean version of defense and veterans pain rating scale for assessment of postoperative pain: a prospective observational cohort study.","authors":"Seungeun Choi, Taeyup Kim, Hae Kyeong Yoo, Sang-Youn Park, Soo-Hyuk Yoon, Ho-Jin Lee","doi":"10.3344/kjp.24346","DOIUrl":"10.3344/kjp.24346","url":null,"abstract":"Background: The defense and veterans pain rating scale (DVPRS) is a pain assessment tool combining a numerical rating scale (NRS) with descriptive words, colors, and facial expressions. This study aimed to validate the Korean version of the DVPRS (K-DVPRS) for postoperative pain assessment.Methods: This study included patients who underwent elective laparoscopic or robotic abdominal surgery. The original DVPRS was translated into Korean using a forward-backward method. Pain intensities at rest and during coughing were assessed at 24 and 48 hours postoperatively using the NRS and K-DVPRS, respectively. The EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire was also used. The validity, reliability, and responsiveness of the K-DVPRS were evaluated.Results: Of the 174 patients screened, 150 were enrolled, and 148 completed the study. The K-DVPRS had strong convergent validity with the NRS at 24 and 48 hours postoperatively (ρ: 0.75 to 0.78, all P < 0.001). Construct validity was confirmed by significant differences in pain scores based on surgical extent and duration. The internal consistency was acceptable (Cronbach's alpha: 0.77 and 0.85 at 24 and 48 hours, respectively), and test-retest reliability at 24 hours was excellent (intraclass correlation coefficient: 0.90 at rest and 0.95 during coughing). Responsiveness, measured by Cliff's effect size, was high from preoperative to 24 hours postoperatively and moderate from 24 to 48 hours. At 48 hours, the K-DVPRS had stronger correlations with the EQ-5D-5L index and EQVAS than with the NRS.Conclusions: The K-DVPRS is a valid, reliable, and responsive tool for assessing postoperative pain in Korean patients.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":" ","pages":"58-68"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptions of treatment, accompanying symptoms, and other problems in patients with chronic pain: a multicenter cross-sectional study in Korea. 慢性疼痛患者对治疗、伴随症状和其他问题的认知：韩国的一项多中心横断面研究

IF 3.4 3区医学

Korean Journal of Pain Pub Date : 2025-01-01 DOI: 10.3344/kjp.24314

Jieun Bae, Yun Hee Lim, Sung Jun Hong, Jae Hun Jeong, Hey Ran Choi, Sun Kyung Park, Jung Eun Kim, Jae Hun Kim

{"title":"Perceptions of treatment, accompanying symptoms, and other problems in patients with chronic pain: a multicenter cross-sectional study in Korea.","authors":"Jieun Bae, Yun Hee Lim, Sung Jun Hong, Jae Hun Jeong, Hey Ran Choi, Sun Kyung Park, Jung Eun Kim, Jae Hun Kim","doi":"10.3344/kjp.24314","DOIUrl":"10.3344/kjp.24314","url":null,"abstract":"Background: Chronic pain significantly affects daily activities, mental health, and the interpersonal relationships of patients. Consequently, physicians use various treatments to manage pain. This study investigated the perceptions of treatment, accompanying symptoms, and other problems in patients with chronic pain.Methods: The authors enrolled patients with chronic pain from 19 university hospitals in South Korea. Data was collected on age, gender, diagnosis, disease duration, severity of pain, perception of pain treatment, and accompanying symptoms or problems using an anonymous survey comprising 19 questions.Results: In total, 833 patients with chronic pain completed the survey, and 257 (31.0%) and 537 (64.5%) patients expressed concerns about the potential adverse effects of medication and opioid addiction, respectively. Personality changes such as irritability or anger were the most frequent accompanying symptoms in 507 (63.8%) patients, followed by depression and sleep disturbance in 462 (58.1%) and 450 (54.5%) patients, respectively. Depression (P = 0.001) and anxiety (P = 0.029) were more common among women, whereas divorce (P = 0.016), family conflict (P < 0.001), unemployment (P < 0.001), suicide attempts (P < 0.001), and restrictions on economic activity (P < 0.001) were more common among men. The frequency of accompanying symptoms, except for suicidal ideation, was higher in the younger patients aged ≤ 40 years than in the older patients aged > 40 years.Conclusions: Many patients with chronic pain had concerns about adverse effects or medication tolerance and experienced anxiety, depression, or sleep disturbances. The prevalence of accompanying problems varies according to age and gender.","PeriodicalId":56252,"journal":{"name":"Korean Journal of Pain","volume":"38 1","pages":"69-78"},"PeriodicalIF":3.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11695254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0