{"title":"Reply to Letter to the Editor: \"A Complex Phenomenon: Medication Overuse Headache and Childhood Experiences\".","authors":"Claire H Sandoe","doi":"10.1017/cjn.2024.307","DOIUrl":"https://doi.org/10.1017/cjn.2024.307","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-2"},"PeriodicalIF":2.9,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is Intimate Partner Violence a Risk Factor for Alzheimer's Disease?","authors":"Nicole Brzozowski, Donald F Weaver","doi":"10.1017/cjn.2024.311","DOIUrl":"https://doi.org/10.1017/cjn.2024.311","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-2"},"PeriodicalIF":2.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bayram Kaymak, Murat Kara, Ahmad Jasem Abdulsalam, Vincenzo Ricci, Levent Özçakar
{"title":"Optimizing Botulinum Toxin Injections by Minding the Muscle Architecture and Its Innervation Zone: The \"Seeding\" Technique.","authors":"Bayram Kaymak, Murat Kara, Ahmad Jasem Abdulsalam, Vincenzo Ricci, Levent Özçakar","doi":"10.1017/cjn.2024.336","DOIUrl":"https://doi.org/10.1017/cjn.2024.336","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-3"},"PeriodicalIF":2.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samira Jafari, Suradech Suthiphosuwan, Jonathan A Micieli
{"title":"Asymptomatic Optic Disc Oedema due to Haematologic Malignancy.","authors":"Samira Jafari, Suradech Suthiphosuwan, Jonathan A Micieli","doi":"10.1017/cjn.2024.334","DOIUrl":"https://doi.org/10.1017/cjn.2024.334","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-2"},"PeriodicalIF":2.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sajeevan Sujanthan, Alisia Southwell, Tera Armel, Elaine Xing, Arunima Kapoor, Xiao Yu Eileen Liu, Krista L Lanctot, Nathan Herrmann, Brian J Murray, Kevin E Thorpe, Megan L Cayley, Michelle N Sicard, Karen Lien, Demetrios J Sahlas, Richard H Swartz
{"title":"Depression, Obstructive Sleep Apnea and Cognitive Impairment (DOC) Screen Completion Time Reflects Executive Function, Speed of Processing and Fluency.","authors":"Sajeevan Sujanthan, Alisia Southwell, Tera Armel, Elaine Xing, Arunima Kapoor, Xiao Yu Eileen Liu, Krista L Lanctot, Nathan Herrmann, Brian J Murray, Kevin E Thorpe, Megan L Cayley, Michelle N Sicard, Karen Lien, Demetrios J Sahlas, Richard H Swartz","doi":"10.1017/cjn.2024.303","DOIUrl":"10.1017/cjn.2024.303","url":null,"abstract":"<p><strong>Background: </strong>The depression, obstructive sleep apnea and cognitive impairment (DOC) screen assesses three post-stroke comorbidities, but additional information may be gained from the time to complete the screen. Cognitive screening completion time is rarely used as an outcome measure.</p><p><strong>Objective: </strong>To assess DOC screen completion time as a predictor of cognitive impairment in stroke/transient ischemic attack clinics.</p><p><strong>Methods: </strong>Consecutive English-speaking stroke prevention clinic patients consented to undergo screening and neuropsychological testing (n = 437). DOC screen scores and times were compared to scores on the NINDS-CSC battery using multiple linear regression (controlling for age, sex, education and stroke severity) and receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>Completion time for the DOC screen was 3.8 ± 1.3 minutes. After accounting for covariates, the completion time was a significant predictor of the speed of processing (<i>p</i> = 0.002, 95% CI: -0.016 to -0.004), verbal fluency (<i>p</i> < 0.001, CI: -0.012 to -0.006) and executive function (<i>p</i> = 0.004, CI: -0.006 to -0.001), but not memory. Completion time above 5.5 minutes was associated with a high likelihood of impairment on executive and speed of processing tasks (likelihood ratios 3.9-5.2).</p><p><strong>Conclusions: </strong>DOC screen completion time is easy to collect in routine care. People needing over 5.5 minutes to be screened likely have deficits in executive functioning and speed of processing - areas commonly impaired, but challenging to screen for, after stroke. DOC screen time provides a simple, feasible approach to assess these under-identified cognitive impairments.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-9"},"PeriodicalIF":2.9,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karlo M Pedro, Guido Guberman, Pasquale Scotti, Ludovic Lafleur, Melissa Hua, Jean-Marc Troquet, Rajeet Singh Saluja, Judith Marcoux
{"title":"Outcomes of Elderly Patients on Direct Oral Anticoagulants (DOACs) Versus Warfarin After Traumatic Brain Injury.","authors":"Karlo M Pedro, Guido Guberman, Pasquale Scotti, Ludovic Lafleur, Melissa Hua, Jean-Marc Troquet, Rajeet Singh Saluja, Judith Marcoux","doi":"10.1017/cjn.2024.347","DOIUrl":"10.1017/cjn.2024.347","url":null,"abstract":"<p><strong>Background: </strong>Although evidence supports the improved safety profile of direct oral anticoagulants (DOACs) over warfarin (WF), outcomes among elderly traumatic brain injury (TBI) patients on this regimen remain unclear. This study describes the association between anticoagulation status (DOAC vs. WF use) and the rates of occurrence of intracranial hemorrhage (ICH), hematoma progression, need for surgical intervention and mortality in elderly TBI cases.</p><p><strong>Methods: </strong>This retrospective cohort study from 2014 to 2019 included all trauma patients > 65 years on either WF or DOACs at the time of injury. The primary outcome was the rate of ICH after TBI. Multivariable regression analysis identified independent predictors of functional dependency and mortality.</p><p><strong>Results: </strong>A total of 501 elderly TBI patients (mean age = 82 years old) were included. WF users had higher CT Marshall scores <i>(p = 0.007)</i>, more severe TBI (GCS < 8) <i>(p = 0.003)</i> and higher rates of subdural hematomas compared to the DOAC group <i>(p = 0.003)</i>. Patients on DOACs had lower rates of ICH <i>(42% vs. 57%, p = 0.001)</i> and hospitalization <i>(30% vs. 41%, p = 0.013)</i> and better Glasgow outcome scale-extended scores at hospital discharge <i>(mean 6.98 vs. 6.41, p = 0.005)</i>. Multicompartment ICH <i>(OR 2.30, p = 0.027)</i> and longer hospitalization <i>(OR 0.04, p < 0.001)</i> were associated with higher functional dependency rates, while higher CT Marshall scores <i>(OR 1.09, p < 0.001)</i> and poorer baseline frailty status <i>(OR 0.62, p = 0.026)</i> predicted increased mortality risk.</p><p><strong>Conclusion: </strong>Elderly TBI patients on DOACs have lower rates of ICH, lower need for hospitalization and better functional outcomes at discharge compared to those taking WF. These findings need further confirmation using prospective multicenter studies.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging for management of chronic Subdural Hematoma- a review.","authors":"Sandeep Devgan, Jai Shankar","doi":"10.1017/cjn.2024.328","DOIUrl":"https://doi.org/10.1017/cjn.2024.328","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-23"},"PeriodicalIF":2.9,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shannon L MacDonald, Elizabeth Linkewich, Mark Bayley, Irene Joo-Hyun Jeong, Jiming Fang, Sue Peters, Jamie L Fleet
{"title":"Males Receive More Intense Inpatient Stroke Rehabilitation Than Females in Ontario, Canada.","authors":"Shannon L MacDonald, Elizabeth Linkewich, Mark Bayley, Irene Joo-Hyun Jeong, Jiming Fang, Sue Peters, Jamie L Fleet","doi":"10.1017/cjn.2024.349","DOIUrl":"10.1017/cjn.2024.349","url":null,"abstract":"<p><p>Increased rehabilitation intensity, the number of minutes of therapy per day, is associated with improved outcomes. However, it is unclear whether males and females receive the same inpatient stroke rehabilitation intensity. A sub-analysis of a retrospective population-based cohort study of adults (5877 females, 6893 males) with stroke discharged to inpatient rehabilitation between 2017 and 2021 was conducted. The mean rehabilitation intensity was 75.86 min/day for males and 73.33 min/day for females (<i>p</i> < .0001). Males <80 years of age were more likely to receive higher rehabilitation intensity than females. Future research should explore what factors account for this sex difference.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-3"},"PeriodicalIF":2.9,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chloe DesRoche, Elaine Innes, Ian Silver, Donatella Tampieri, Benjamin Y M Kwan, Johanna Ortiz Jimenez, Omar Islam
{"title":"Utility of novel ultra-low field portable MRI in a remote setting in Canada.","authors":"Chloe DesRoche, Elaine Innes, Ian Silver, Donatella Tampieri, Benjamin Y M Kwan, Johanna Ortiz Jimenez, Omar Islam","doi":"10.1017/cjn.2024.346","DOIUrl":"10.1017/cjn.2024.346","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-18"},"PeriodicalIF":2.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}