Canadian Journal of Neurological Sciences最新文献

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Health Care Encounters Prior to Hospitalization for Cerebral Venous Thrombosis Patients. 脑静脉血栓患者住院前的医护接触。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-12 DOI: 10.1017/cjn.2024.48
Zeina Waheed, Thalia S Field, Lily W Zhou
{"title":"Health Care Encounters Prior to Hospitalization for Cerebral Venous Thrombosis Patients.","authors":"Zeina Waheed, Thalia S Field, Lily W Zhou","doi":"10.1017/cjn.2024.48","DOIUrl":"10.1017/cjn.2024.48","url":null,"abstract":"<p><strong>Background: </strong>Unlike other causes of stroke, symptoms in cerebral venous thrombosis (CVT) can be nonspecific at onset with gradual worsening over time. To explore potential opportunities for earlier diagnosis, we analyzed healthcare interactions in the week prior to hospitalization for patients admitted with incident CVT in British Columbia (BC).</p><p><strong>Methods: </strong>We constructed a population-based cohort (2000-2017) using linked patient-level administrative data to identify patients aged ≥18 diagnosed with CVT in BC. We used descriptive analysis to describe the frequency and types of healthcare encounters within the 7 and 3 days prior to hospitalization. Multivariable logistic regression modeling was performed to examine risk factors associated with prior encounters.</p><p><strong>Results: </strong>The cohort included 554 patients (mean age 50.9 years, 55.4% female). Within the 7 days prior to CVT hospitalization, 57.9% of patients had ≥1 outpatient encounter and 5.6% had ≥1 inpatient encounter. In the 3 days prior to hospitalization, 46.8% of patients had ≥1 outpatient encounter and 2.0% had ≥1 inpatient encounter. Women more frequently had outpatient interactions within 7 days (64.8% women vs. 35.2% men, <i>p</i> < 0.001) and 3 days (51.8% vs. 48.2%, <i>p</i> = 0.01) before admission. Common provider specialties for outpatient encounters were general practice (58.0%), emergency (8.3%) and neurology (5.7%). Females had higher odds (OR = 1.79) of having ≥1 outpatient encounter after adjusting for confounding.</p><p><strong>Conclusions: </strong>Within our Canadian cohort, over half of patients had a healthcare encounter within 7 days before their hospitalization with incident CVT. Women more commonly had an outpatient encounter preceding hospital admission.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geographical Variation In Medication and Health Resource Use In Multiple Sclerosis. 多发性硬化症患者在药物和医疗资源使用方面的地域差异。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-11 DOI: 10.1017/cjn.2024.54
Erin F Balcom, Jennifer A McCombe, Mahesh Kate, Khanh Vu, Karen J B Martins, Sylvia Aponte-Hao, Huong Luu, Lawrence Richer, Tyler Williamson, Scott W Klarenbach, Penelope Smyth
{"title":"Geographical Variation In Medication and Health Resource Use In Multiple Sclerosis.","authors":"Erin F Balcom, Jennifer A McCombe, Mahesh Kate, Khanh Vu, Karen J B Martins, Sylvia Aponte-Hao, Huong Luu, Lawrence Richer, Tyler Williamson, Scott W Klarenbach, Penelope Smyth","doi":"10.1017/cjn.2024.54","DOIUrl":"10.1017/cjn.2024.54","url":null,"abstract":"<p><strong>Background: </strong>Understanding disease-modifying therapy (DMT) use and healthcare resource utilization by different geographical areas among people living with multiple sclerosis (pwMS) may identify care gaps that can be used to inform policies and practice to ensure equitable care.</p><p><strong>Methods: </strong>Administrative data was used to identify pwMS on April 1, 2017 (index date) in Alberta. DMT use and healthcare resource utilization were compared between those who resided in various geographical areas over a 2-year post-index period; simple logistic regression was applied.</p><p><strong>Results: </strong>Among the cohort (<i>n</i> = 12,338), a higher proportion of pwMS who resided in urban areas (versus rural) received ≥ 1 DMT dispensation (32.3% versus 27.4%), had a neurologist (67.7% versus 63.9%), non-neurologist specialist (88.3% versus 82.9%), ambulatory care visit (87.4% versus 85.3%), and MS tertiary clinic visit (59.2% versus 51.7%), and a lower proportion had an emergency department (ED) visit (46.3% versus 62.4%), and hospitalization (20.4% versus 23.0%). Across the provincial health zones, there were variations in DMT selection, and a higher proportion of pwMS who resided in the Calgary health zone, where care is managed by MS tertiary clinic neurologists, had an outpatient visit to a neurologist or MS tertiary clinic versus those who resided in other zones where delivery of MS-related care is more varied.</p><p><strong>Conclusions: </strong>Urban/rural inequalities in DMT use and healthcare resource utilization appear to exist among pwMS in Alberta. Findings suggest the exploration of barriers with consequent strategies to increase access to DMTs and provide timely outpatient MS care management, particularly for those pwMS residing in rural areas.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140862813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disparities In Drug-Resistant Epilepsy Care In Canada. 加拿大抗药性癫痫护理中的差异。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-11 DOI: 10.1017/cjn.2024.57
R Grace Couper, Tresah Antaya, Dang K Nguyen, Jorge G Burneo
{"title":"Disparities In Drug-Resistant Epilepsy Care In Canada.","authors":"R Grace Couper, Tresah Antaya, Dang K Nguyen, Jorge G Burneo","doi":"10.1017/cjn.2024.57","DOIUrl":"https://doi.org/10.1017/cjn.2024.57","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive Thrombosis of a Dolicho-Basilar Artery and Fusiform Aneurysm Resulting in Diffuse Ischemic and Hemorrhagic Complications. 多立霍-基底动脉和纺锤形动脉瘤的进行性血栓形成导致弥漫性缺血和出血并发症。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-04 DOI: 10.1017/cjn.2024.51
Vincent Brissette, Marina Saad, Devavrat Nene, Christine Van Winssen, Ange Boubacar Diouf, Marlise P Dos Santos, Robert Fahed, Célina Ducroux
{"title":"Progressive Thrombosis of a Dolicho-Basilar Artery and Fusiform Aneurysm Resulting in Diffuse Ischemic and Hemorrhagic Complications.","authors":"Vincent Brissette, Marina Saad, Devavrat Nene, Christine Van Winssen, Ange Boubacar Diouf, Marlise P Dos Santos, Robert Fahed, Célina Ducroux","doi":"10.1017/cjn.2024.51","DOIUrl":"https://doi.org/10.1017/cjn.2024.51","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Evolving Role of Electroencephalography in Postarrest Care. 脑电图在逮捕后护理中不断演变的作用。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-04 DOI: 10.1017/cjn.2024.55
Caralyn Bencsik, Colin Josephson, Andrea Soo, Craig Ainsworth, Martin Savard, Sean van Diepen, Andreas Kramer, Julie Kromm
{"title":"The Evolving Role of Electroencephalography in Postarrest Care.","authors":"Caralyn Bencsik, Colin Josephson, Andrea Soo, Craig Ainsworth, Martin Savard, Sean van Diepen, Andreas Kramer, Julie Kromm","doi":"10.1017/cjn.2024.55","DOIUrl":"https://doi.org/10.1017/cjn.2024.55","url":null,"abstract":"<p><p>Electroencephalography is an accessible, portable, noninvasive and safe means of evaluating a patient's brain activity. It can aid in diagnosis and management decisions for post-cardiac arrest patients with seizures, myoclonus and other non-epileptic movements. It also plays an important role in a multimodal approach to neuroprognostication predicting both poor and favorable outcomes. Individuals ordering, performing and interpreting these tests, regardless of the indication, should understand the supporting evidence, logistical considerations, limitations and impact the results may have on postarrest patients and their families as outlined herein.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Canadian Practice and Recommendations on Functional MRI to Lateralize Language in Epilepsy. 加拿大功能磁共振成像用于癫痫患者语言侧位的实践和建议。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-04 DOI: 10.1017/cjn.2024.56
Madeleine R Falby, Donald C Brien, Lysa Boissé Lomax, Garima Shukla, Gavin P Winston
{"title":"Canadian Practice and Recommendations on Functional MRI to Lateralize Language in Epilepsy.","authors":"Madeleine R Falby, Donald C Brien, Lysa Boissé Lomax, Garima Shukla, Gavin P Winston","doi":"10.1017/cjn.2024.56","DOIUrl":"https://doi.org/10.1017/cjn.2024.56","url":null,"abstract":"<p><strong>Background/objective: </strong>Identifying a patient's dominant language hemisphere is an important evaluation performed prior to epilepsy surgery and is commonly assessed using functional magnetic resonance imaging (fMRI). However, the lack of standardization and resultant heterogeneity of fMRI paradigms used in clinical practice limits the ability of cross-center comparisons to be made regarding language laterality results.</p><p><strong>Methods: </strong>Through surveying Canadian Epilepsy Centres in combination with reviewing supporting literature, current fMRI language lateralization practices for the clinical evaluation of patients with epilepsy were assessed. To encourage standardization of this practice, we outlined a two-part paradigm series that demonstrates widespread acceptance, reliability and accessibility in lateralizing various aspects of language functioning in individuals with average or near-average IQ and normal literacy skills.</p><p><strong>Results: </strong>The collected data confirm a lack of standardization in fMRI laterality assessments leading to clinical heterogeneity in stimulation and control tasks, paradigm design and timing, laterality index calculations, thresholding values and analysis software and technique. We suggest a Sentence Completion (SC) and Word Generation (WG) paradigm series as it was most commonly employed across Canada, demonstrated reliability in lateralizing both receptive and expressive language areas in supporting literature, and could be readily intelligible to an inclusive population.</p><p><strong>Conclusion: </strong>Through providing recommendations for a two-part paradigm series, we hope to contribute to the standardization of this practice across Canada to reduce clinical heterogeneity, encourage communicability between institutions, and enhance methodologies for the surgical treatment of epilepsy for the benefit of all individuals living with epilepsy in Canada.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reported Case Report of Recovery from Rabies Using Intrathecal Rabies Immune Globulin was Flawed - ADDENDUM. 使用鞘内注射狂犬病免疫球蛋白治愈狂犬病的病例报告存在缺陷 - 增补。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-04 DOI: 10.1017/cjn.2024.39
Alan C Jackson, Charles E Rupprecht, Reeta S Mani, Nidia Aréchiga-Ceballos, Darryn L Knobel
{"title":"Reported Case Report of Recovery from Rabies Using Intrathecal Rabies Immune Globulin was Flawed - ADDENDUM.","authors":"Alan C Jackson, Charles E Rupprecht, Reeta S Mani, Nidia Aréchiga-Ceballos, Darryn L Knobel","doi":"10.1017/cjn.2024.39","DOIUrl":"https://doi.org/10.1017/cjn.2024.39","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Commercially Available Seizure Detection Wearables in Canada: Current Evidence. 对加拿大市售癫痫发作检测可穿戴设备的评估:当前证据。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-04 DOI: 10.1017/cjn.2024.58
Yassine Lamrani, Amirhossein Jahani, Laura Gagliano, Dang Khoa Nguyen, Elie Bou Assi
{"title":"Evaluation of Commercially Available Seizure Detection Wearables in Canada: Current Evidence.","authors":"Yassine Lamrani, Amirhossein Jahani, Laura Gagliano, Dang Khoa Nguyen, Elie Bou Assi","doi":"10.1017/cjn.2024.58","DOIUrl":"10.1017/cjn.2024.58","url":null,"abstract":"<p><p>Wearable-based seizure detection devices hold promise in reducing seizure-related adverse events and relieving the daily stress experienced by people with epilepsy. In this work, we present the latest evidence regarding the performance of three seizure detection wearables (eight studies) commercially available in Canada to provide guidance to clinicians. Overall, their ability to detect focal-to-bilateral and/or generalized tonic-clonic seizures ranges between 21.0% and 98.15% in sensitivity, with the 24h false alarm rates ranging from 0 to 1.28. While performance in epilepsy monitoring units show promise, the lack of evidence in outpatient settings precludes strong recommendations for their use in daily life.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nitrous Oxide-Induced Myelopathy Mimicking Longitudinally Extensive Transverse Myelitis. 模仿纵向扩展横贯性脊髓炎的一氧化二氮诱发脊髓病变
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-02 DOI: 10.1017/cjn.2024.50
Chia-Chen Tsai, Tychicus Chen
{"title":"Nitrous Oxide-Induced Myelopathy Mimicking Longitudinally Extensive Transverse Myelitis.","authors":"Chia-Chen Tsai, Tychicus Chen","doi":"10.1017/cjn.2024.50","DOIUrl":"10.1017/cjn.2024.50","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survey of Canadian Physician Use of Botulinum Toxin A (BoNT-A) for Paratonia: Real World Insights. 加拿大医生使用肉毒杆菌毒素-A(BoNT-A)治疗瘫痪的调查:真实世界的洞察力。
IF 3 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2024-04-01 DOI: 10.1017/cjn.2024.46
Galit Kleiner, Farooq Ismail, Omar Khan, Christopher Pilieci, Linda Truong, Chris Boulias
{"title":"Survey of Canadian Physician Use of Botulinum Toxin A (BoNT-A) for Paratonia: Real World Insights.","authors":"Galit Kleiner, Farooq Ismail, Omar Khan, Christopher Pilieci, Linda Truong, Chris Boulias","doi":"10.1017/cjn.2024.46","DOIUrl":"10.1017/cjn.2024.46","url":null,"abstract":"<p><p>Paratonia is a form of hypertonia characterized by an inability to relax muscles in the setting of cognitive impairment. Paratonia results in pain, refusal of care, and caregiver burden. We sent surveys to 67 Canadian physiatrists and neurologists regarding their experience treating paratonia with botulinum toxin A (BoNT-A). Twenty-seven survey respondents were included in the analysis. Thirteen percent of survey respondents treating paratonia with BoNT-A reported a significant clinically relevant improvement; 74% endorsed a moderately clinically relevant improvement; 13% endorsed a slight clinically relevant improvement. Ninety percent of survey respondents endorsed significant barriers in treating paratonia with BoNT-A.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140332351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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