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Left-sided Neurological Symptoms and Negative Diffusion-Weighted MRI in Suspected Minor Stroke Patients. 疑似轻微脑卒中患者的左侧神经症状和阴性弥散加权MRI。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-27 DOI: 10.1017/cjn.2025.10125
Umberto Pensato, Nishita Singh, Raed A Joundi, Koji Tanaka, Andrew M Penn, Kristine Votova, Maximilian M B Bibok, Robert F Balshaw, Andrew M Demchuk, Michael D Hill, Shelagh B Coutts
{"title":"Left-sided Neurological Symptoms and Negative Diffusion-Weighted MRI in Suspected Minor Stroke Patients.","authors":"Umberto Pensato, Nishita Singh, Raed A Joundi, Koji Tanaka, Andrew M Penn, Kristine Votova, Maximilian M B Bibok, Robert F Balshaw, Andrew M Demchuk, Michael D Hill, Shelagh B Coutts","doi":"10.1017/cjn.2025.10125","DOIUrl":"https://doi.org/10.1017/cjn.2025.10125","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-16"},"PeriodicalIF":2.9,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and real-world effectiveness in the transition from Alteplase to Tenecteplase for stroke treatment. 卒中治疗从阿替普酶过渡到替奈替普酶的安全性和实际有效性。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-27 DOI: 10.1017/cjn.2025.10121
Mary-Lou Halabi, Jillian Stang, Bijoy K Menon, Brian H Buck, Christiane J McIntosh, Stephen B Wilton, Shelley Valaire, Balraj Mann, Lisa Collins, Colleen Taralson, Lindsay Beaulieu, Elaine Shand, Corinna Hartley, Chelsey Dalgleish, Anthony Nickonchuk, Shannon Erfle, Oje Imoukhuede, H Alejandro M Alzate, Katie Lin, Shelagh B Coutts, Thomas Jeerakathil, Ashfaq Shuaib, Andrew M Demchuk, Michael D Hill
{"title":"Safety and real-world effectiveness in the transition from Alteplase to Tenecteplase for stroke treatment.","authors":"Mary-Lou Halabi, Jillian Stang, Bijoy K Menon, Brian H Buck, Christiane J McIntosh, Stephen B Wilton, Shelley Valaire, Balraj Mann, Lisa Collins, Colleen Taralson, Lindsay Beaulieu, Elaine Shand, Corinna Hartley, Chelsey Dalgleish, Anthony Nickonchuk, Shannon Erfle, Oje Imoukhuede, H Alejandro M Alzate, Katie Lin, Shelagh B Coutts, Thomas Jeerakathil, Ashfaq Shuaib, Andrew M Demchuk, Michael D Hill","doi":"10.1017/cjn.2025.10121","DOIUrl":"https://doi.org/10.1017/cjn.2025.10121","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-16"},"PeriodicalIF":2.9,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring migraine in Canada and the United States: An online survey of emergency room and smartphone application use. 测量加拿大和美国的偏头痛：一项关于急诊室和智能手机应用程序使用的在线调查。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-25 DOI: 10.1017/cjn.2025.10140
Andrea Portt, Christine Lay, Hong Chen, Erjia Ge, Peter Smith
{"title":"Measuring migraine in Canada and the United States: An online survey of emergency room and smartphone application use.","authors":"Andrea Portt, Christine Lay, Hong Chen, Erjia Ge, Peter Smith","doi":"10.1017/cjn.2025.10140","DOIUrl":"https://doi.org/10.1017/cjn.2025.10140","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-33"},"PeriodicalIF":2.9,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Role of Post-Thrombectomy MRI in Predicting Functional Recovery in Basilar Artery Occlusion. 评价取栓后MRI在预测基底动脉闭塞患者功能恢复中的作用。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-24 DOI: 10.1017/cjn.2025.10347
Nahal Farhani, Marco Ayroso, Susan Alcock, Jai Shankar
{"title":"Evaluating the Role of Post-Thrombectomy MRI in Predicting Functional Recovery in Basilar Artery Occlusion.","authors":"Nahal Farhani, Marco Ayroso, Susan Alcock, Jai Shankar","doi":"10.1017/cjn.2025.10347","DOIUrl":"https://doi.org/10.1017/cjn.2025.10347","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-20"},"PeriodicalIF":2.9,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leptomeningeal Carcinomatosis from Triple-Negative Breast Cancer Presenting with Acute Bilateral Optic Neuropathy. 以急性双侧视神经病变为表现的三阴性乳腺癌轻脑膜癌。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-18 DOI: 10.1017/cjn.2025.10118
Arshia Eshtiaghi, Gary Yau, Rahul A Sharma, Edsel Ing, Matylda Machnowska, Arun Ne Sundaram
{"title":"Leptomeningeal Carcinomatosis from Triple-Negative Breast Cancer Presenting with Acute Bilateral Optic Neuropathy.","authors":"Arshia Eshtiaghi, Gary Yau, Rahul A Sharma, Edsel Ing, Matylda Machnowska, Arun Ne Sundaram","doi":"10.1017/cjn.2025.10118","DOIUrl":"https://doi.org/10.1017/cjn.2025.10118","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-7"},"PeriodicalIF":2.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Central Nervous System Melanoma With Bilateral Vestibular Lesions Mimicking Neurofibromatosis Type 2. 原发性中枢神经系统黑色素瘤伴双侧前庭病变，酷似2型神经纤维瘤病。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-16 DOI: 10.1017/cjn.2025.10343
Kenneth Ong, Celine Hounjet, Alexander D Rebchuk, Jeremy Kam, Nicolas Dea, Ian Mackenzie, Saba Vafaei-Nodeh, Ryojo Akagami, Steven Yip, Mostafa Fatehi
{"title":"Primary Central Nervous System Melanoma With Bilateral Vestibular Lesions Mimicking Neurofibromatosis Type 2.","authors":"Kenneth Ong, Celine Hounjet, Alexander D Rebchuk, Jeremy Kam, Nicolas Dea, Ian Mackenzie, Saba Vafaei-Nodeh, Ryojo Akagami, Steven Yip, Mostafa Fatehi","doi":"10.1017/cjn.2025.10343","DOIUrl":"https://doi.org/10.1017/cjn.2025.10343","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using titanium clips to close the dura in minimally invasive spinal surgery: an efficient and easy-to-use technique. 微创脊柱手术中使用钛夹闭合硬脑膜：一种有效且易于使用的技术。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-16 DOI: 10.1017/cjn.2025.10344
Leonardo Olijnyk, Paul Kaseir, Tristan Brunette-Clément, Antoine Gennari, Daniel Shedid, Sunj-Joo Yuh
{"title":"Using titanium clips to close the dura in minimally invasive spinal surgery: an efficient and easy-to-use technique.","authors":"Leonardo Olijnyk, Paul Kaseir, Tristan Brunette-Clément, Antoine Gennari, Daniel Shedid, Sunj-Joo Yuh","doi":"10.1017/cjn.2025.10344","DOIUrl":"https://doi.org/10.1017/cjn.2025.10344","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-12"},"PeriodicalIF":2.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First-line use of higher-efficacy disease-modifying therapies in multiple sclerosis: Canadian consensus recommendations. 在多发性硬化症中一线使用更有效的疾病改善疗法：加拿大的共识建议。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-09 DOI: 10.1017/cjn.2025.10342
Mark S Freedman, Fraser Clift, Virginia Devonshire, François Émond, Catherine Larochelle, Michael C Levin, Heather MacLean, Sarah A Morrow, Alexandre Prat, Daniel Selchen, Penelope Smyth, Galina Vorobeychik
{"title":"First-line use of higher-efficacy disease-modifying therapies in multiple sclerosis: Canadian consensus recommendations.","authors":"Mark S Freedman, Fraser Clift, Virginia Devonshire, François Émond, Catherine Larochelle, Michael C Levin, Heather MacLean, Sarah A Morrow, Alexandre Prat, Daniel Selchen, Penelope Smyth, Galina Vorobeychik","doi":"10.1017/cjn.2025.10342","DOIUrl":"https://doi.org/10.1017/cjn.2025.10342","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-28"},"PeriodicalIF":2.9,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review: mental health outcomes in Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy. 系统评价：格林-巴利综合征和慢性炎症性脱髓鞘多神经病变的心理健康结局。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-09 DOI: 10.1017/cjn.2025.10107
Cathy Meng Fei Li, Stanley Wong, Nicholas Fabiano, Carol Li, Matthew McShane, Alla Iansavitchene, Michael W Nicolle
{"title":"Systematic review: mental health outcomes in Guillain-Barre syndrome and chronic inflammatory demyelinating polyneuropathy.","authors":"Cathy Meng Fei Li, Stanley Wong, Nicholas Fabiano, Carol Li, Matthew McShane, Alla Iansavitchene, Michael W Nicolle","doi":"10.1017/cjn.2025.10107","DOIUrl":"https://doi.org/10.1017/cjn.2025.10107","url":null,"abstract":"","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-27"},"PeriodicalIF":2.9,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing Motor Cortex Excitability and Its Relationship with Cortical Atrophy in Alzheimer's Dementia. 阿尔茨海默氏痴呆患者运动皮质兴奋性评估及其与皮质萎缩的关系。
IF 2.9 4区 医学
Canadian Journal of Neurological Sciences Pub Date : 2025-06-09 DOI: 10.1017/cjn.2025.79
Renée P Lawson, Reza Zomorrodi, Michael Joseph, Hiba Alhabbal, Gifty Asare, Daniel M Blumberger, Zafiris J Daskalakis, Corinne E Fischer, Benoit H Mulsant, Bruce G Pollock, Tarek K Rajji, Aristotle N Voineskos, Sanjeev Kumar
{"title":"Assessing Motor Cortex Excitability and Its Relationship with Cortical Atrophy in Alzheimer's Dementia.","authors":"Renée P Lawson, Reza Zomorrodi, Michael Joseph, Hiba Alhabbal, Gifty Asare, Daniel M Blumberger, Zafiris J Daskalakis, Corinne E Fischer, Benoit H Mulsant, Bruce G Pollock, Tarek K Rajji, Aristotle N Voineskos, Sanjeev Kumar","doi":"10.1017/cjn.2025.79","DOIUrl":"https://doi.org/10.1017/cjn.2025.79","url":null,"abstract":"<p><strong>Background: </strong>Cortical excitability has been proposed as a novel neurophysiological marker of neurodegeneration in Alzheimer's dementia (AD). However, the link between cortical excitability and structural changes in AD is not well understood.</p><p><strong>Objective: </strong>To assess the relationship between cortical excitability and motor cortex thickness in AD.</p><p><strong>Methods: </strong>In 62 participants with AD (38 females, mean ± SD age = 74.6 ± 8.0) and 47 healthy control (HC) individuals (26 females, mean ± SD age = 71.0 ± 7.9), transcranial magnetic stimulation resting motor threshold (rMT) was determined, and T1-weighted MRI scans were obtained. Skull-to-cortex distance was obtained manually for each participant using MNI coordinates of the motor cortex (x = -40, y = -20, z = 52).</p><p><strong>Results: </strong>The mean skull-to-cortex distances did not differ significantly between participants with AD (22.9 ± 4.3 mm) and HC (21.7 ± 4.3 mm). Participants with AD had lower motor cortex thickness than healthy individuals (<i>t</i>(92) = -4.4, <i>p</i> = <0.001) and lower rMT (i.e., higher excitability) than HC (<i>t</i>(107) = -2.0, <i>p</i> = 0.045). In the combined sample, rMT was correlated positively with motor cortex thickness (<i>r</i> = 0.2, <i>df</i> = 92, <i>p</i> = 0.036); however, this association did not remain significant after controlling for age, sex and diagnosis.</p><p><strong>Conclusions: </strong>Patients with AD have decreased cortical thickness in the motor cortex and higher motor cortex excitability. This suggests that cortical excitability may be a marker of neurodegeneration in AD.</p>","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-8"},"PeriodicalIF":2.9,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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