Canadian Journal of Neurological Sciences最新文献_第7页

Quality Improvement in Deep Brain Stimulation for Movement Disorders: Pandemic Impact on Specialized Elective Surgery. 脑深部刺激治疗运动障碍的质量改善：对专科选择性手术的大流行影响。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-12-06 DOI: 10.1017/cjn.2024.353

Kevin Yen, Pouria Torabi, Janis M Miyasaki, Tejas Sankar, Fang Ba

引用次数: 0

Impact of Clinical Trial Enrollment on Thrombolysis Workflow in a Mobile Stroke Unit: Results from the AcT Trial. 临床试验入组对流动卒中单元溶栓工作流程的影响：AcT试验结果。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-12-06 DOI: 10.1017/cjn.2024.354

Gurpreet Chaggar, Arth Pahwa, Brian H Buck, Thomas Jeerakathil, Ashfaq Shuaib, Mohammed Almekhlafi, Richard Swartz, Asif Butt, Luciana Catanese, Nishita Singh, Aleksander Tkach, Tolulope T Sajobi, Bijoy K Menon, Mahesh Kate

{"title":"Impact of Clinical Trial Enrollment on Thrombolysis Workflow in a Mobile Stroke Unit: Results from the AcT Trial.","authors":"Gurpreet Chaggar, Arth Pahwa, Brian H Buck, Thomas Jeerakathil, Ashfaq Shuaib, Mohammed Almekhlafi, Richard Swartz, Asif Butt, Luciana Catanese, Nishita Singh, Aleksander Tkach, Tolulope T Sajobi, Bijoy K Menon, Mahesh Kate","doi":"10.1017/cjn.2024.354","DOIUrl":"10.1017/cjn.2024.354","url":null,"abstract":"Background: The Edmonton-based mobile stroke unit (MSU), which transports patients to the University of Alberta Hospital (UAH), enrolled patients in the Intravenous Tenecteplase Compared with Alteplase for Acute Ischemic Stroke (AcT) trial. We examined the feasibility of trial enrollment in MSU, its impact on acute stroke workflow metrics and functional outcomes at 90-120 days.Methods: In this post hoc analysis, patients were divided into three groups based on enrollment site: MSU (n = 43), UAH (n = 273) and non-UAH (n = 1261). All patients were enrolled with a deferred consent process. The primary outcome for this analysis was the feasibility of enrollment defined as the proportion of patients receiving intravenous thrombolysis (IVT) during the study period who were enrolled in the trial. Multiple linear and binary logistic regression was used to evaluate the adjusted effect of the study groups on acute stroke workflow metrics and functional outcomes at 90-120 days.Results: 100% of eligible IVT-treated patients in the MSU during the study period were enrolled in the AcT trial. Covariate-adjusted linear regression showed shorter door-to-needle (17.2 [9.7-24.6] min) and CT-to-needle (10.7 [4.2-17.1] min) times in the MSU compared to UAH and non-UAH sites. There was no difference in the proportion of patients with an excellent functional outcome (mRS 0-1) at 90-120 days or symptomatic intracerebral hemorrhage (ICH) at 24 hours between groups.Conclusions: Enrollment in the AcT trial from the MSU was feasible. MSU-enrolled patients demonstrated faster door-to-needle and CT-to-needle times, resulting in earlier IVT administration and similar rates of symptomatic ICH.","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Canadian Stroke Best Practice Recommendations, 7th Edition: Cerebral Venous Thrombosis, 2024 - CORRIGENDUM. 加拿大卒中最佳实践建议，第7版：脑静脉血栓形成，2024 -勘误表。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-12-06 DOI: 10.1017/cjn.2024.350

Thalia S Field, M Patrice Lindsay, Theodore Wein, Derek B Debicki, Johnathon Gorman, Manraj K S Heran, Leonard A Levin, Rebecca Lund, Mahendranath Moharir, Lissa Peeling, Kanjana S Perera, Deborah Siegal, Steve Verreault, Norine Foley, Chelsy Martin, Eric E Smith, Anita Mountain, Jennifer Mandzia

引用次数: 0

Automatic Matching Algorithms to Identify Eligible Participants for Stroke Trials: A Proof-of-Concept Study. 自动匹配算法识别卒中试验的合格参与者：概念验证研究。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-12-05 DOI: 10.1017/cjn.2024.352

Pattarawut Charatpangoon, Nishita Singh, Brian H Buck, Federico Carpani, Luciana Catanese, Shelagh B Coutts, Thalia S Field, Gary Hunter, Houman Khosravani, Kanjana Perera, Tolulope T Sajobi, Michel Shamy, Jai Jai Shiva Shankar, Aleksander Tkach, Richard H Swartz, Mohammed A Almekhlafi, Bijoy K Menon, M Ethan MacDonald, Aravind Ganesh

引用次数: 0

Basal Ganglia Involvement in Susac Syndrome During Pregnancy. 妊娠期Susac综合征与基底神经节的关系。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-12-03 DOI: 10.1017/cjn.2024.306

Erin Nuro, Cathy Meng Fei Li, Andrew Leung, Lillian Barra, Anita Dayal-Harbour, Jennifer Mandzia

引用次数: 0

Rare Spinocerebellar Ataxia Types in Canada: A Case Series and Review of the Literature. 加拿大罕见的脊髓小脑性共济失调类型：病例系列和文献综述。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-12-02 DOI: 10.1017/cjn.2024.335

Sohaila Alshimemeri, Lamya Alsaghan, Danah Abo Alsamh, Lily Zhou, Sarah Furtado, Scott Kraft, Veronica Bruno, Silke Appel-Cresswell, Antoine Duquette, Bernard Brais, Oksana Suchowersky, Elizabeth Slow, Renato P Munhoz

{"title":"Rare Spinocerebellar Ataxia Types in Canada: A Case Series and Review of the Literature.","authors":"Sohaila Alshimemeri, Lamya Alsaghan, Danah Abo Alsamh, Lily Zhou, Sarah Furtado, Scott Kraft, Veronica Bruno, Silke Appel-Cresswell, Antoine Duquette, Bernard Brais, Oksana Suchowersky, Elizabeth Slow, Renato P Munhoz","doi":"10.1017/cjn.2024.335","DOIUrl":"https://doi.org/10.1017/cjn.2024.335","url":null,"abstract":"Background: There is limited information on rare spinocerebellar ataxia (SCA) variants, particularly in the Canadian population. This study aimed to describe the demographic and clinical features of uncommon SCA subtypes in Canada and compare them with international data.Methods: We conducted a case series and literature review of adult patients with rare SCA subtypes, including SCA5, SCA7, SCA12, SCA14, SCA15, SCA28, SCA34, SCA35 and SCA36. Data were collected from medical centers in Ontario, Alberta and Quebec between January 2000 and February 2021.Results: We analyzed 25 patients with rare SCA subtypes, with onset ages ranging from birth to 67 years. Infantile and juvenile-onset cases were observed in SCA5, SCA7, SCA14 and SCA34. Most patients presented with gait ataxia, with no significant differences across groups. Additional common features included saccadic abnormalities (22 of 25), dysarthria (19 of 25) and nystagmus (12 of 22, except in SCA7). Less common findings included dystonia (8 of 25), cognitive impairment (7 of 25), tremor (9 of 25) and parkinsonism (3 of 25).Conclusion: Our study highlights the heterogeneity of rare SCA subtypes in Canada. Ongoing longitudinal analysis will improve the understanding, management and screening of these disorders.","PeriodicalId":56134,"journal":{"name":"Canadian Journal of Neurological Sciences","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerebellar Vascular Malformation of Unknown Aetiology with Recent COVID-19 Infection. 小脑血管畸形，病因不明，近期感染 COVID-19。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-11-28 DOI: 10.1017/cjn.2024.301

Diana Chang, Satoshi Tateshima, Karam Han, Hilda Mirbaha, Charles Beaman, Geoffrey P Colby, Noriko Salamon, Harry V Vinters, Anthony C Wang

引用次数: 0

A Complex Phenomenon: Medication Overuse Headache and Childhood Experiences. 复杂的现象：用药过度头痛与童年经历。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-11-27 DOI: 10.1017/cjn.2024.305

Prateek Kumar Panda, Indar Kumar Sharawat

引用次数: 0

FLVCR1 Gene Mutation in a Patient with an Atypical Multiple Sclerosis-Like Presentation. 一名非典型多发性硬化症患者的 FLVCR1 基因突变

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-11-27 DOI: 10.1017/cjn.2024.351

Qais Sa'di, Saba Alsmadi, Wanas Shtaiyat, Mohammad Qasaimeh, Renato Puppi Munhoz

引用次数: 0

Management Approaches to Intraluminal Thrombi in Acutely Symptomatic Carotid Stenosis. 急性症状性颈动脉狭窄的管腔内血栓处理方法。

IF 2.9 4区医学

Canadian Journal of Neurological Sciences Pub Date : 2024-11-27 DOI: 10.1017/cjn.2024.348

Davis MacLean, Benjamin Beland, Gordon A E Jewett, Luca Bartolini, David J T Campbell, Malavika Varma, Ravinder-Jeet Singh, John H Wong, Bijoy K Menon, Aravind Ganesh

引用次数: 0