Oral RadiologyPub Date : 2024-02-26DOI: 10.1007/s11282-024-00743-9
Esra Yavuz, Selmi Yardimci
{"title":"Comparison of periapical radiography, panoramic radiography, and CBCT in the evaluation of trabecular bone structure using fractal analysis","authors":"Esra Yavuz, Selmi Yardimci","doi":"10.1007/s11282-024-00743-9","DOIUrl":"https://doi.org/10.1007/s11282-024-00743-9","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>The aim of this study is to compare imaging techniques to evaluate trabecular bone structure using Fractal Analysis (FA).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>Fifteen sheep hemimandibles were used for this study. Digital images were obtained using periapical radiography, panoramic radiography, and cone-beam computed tomography (CBCT). CBCT imaging was performed in standard (STD) and high-resolution (HR) modes. FA was conducted using ImageJ 1.3 software with the box-counting method on the images. The fractal dimension (FD) values were analyzed by the statistical software Jamovi 1.6.23. Statistical significance was accepted as <i>p</i> < 0.05.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>The highest mean FD value was the FD on digital periapical radiographs (PaFD) (1.28 ± 0.04), and the lowest mean FD value was the FD on standard resolution cone-beam computed tomography images (STD-CBCTFD) (1.12 ± 0.10). Although there was no statistically significant difference between the PaFD and the FD on digital panoramic radiographs (PanFD) (<i>p</i> = 0.485), the PaFD was found to be significantly higher than STD-CBCTFD (<i>p</i> < 0.001), and the FD on high-resolution cone-beam computed tomography images (HR-CBCTFD) (<i>p</i> = 0.007). The PanFD was found to be significantly higher than the STD-CBCTFD (<i>p</i> = 0.004).</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>According to our results, in the evaluation of trabecular bone structure using FA, periapical radiographs and panoramic radiographs have similar image quality for assessment of the FD. On the other hand, CBCT results did not correlate with results from any of the other techniques in this study.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139969252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2024-02-03DOI: 10.1007/s11282-024-00740-y
Yoshitaka Kise, Anne Møystad, Chiaki Kuwada, Eiichiro Ariji, Tore Bjørnland
{"title":"Does ultrasound elastography have a role as a diagnostic method for Sjögren’s syndrome in the salivary glands? A systematic review","authors":"Yoshitaka Kise, Anne Møystad, Chiaki Kuwada, Eiichiro Ariji, Tore Bjørnland","doi":"10.1007/s11282-024-00740-y","DOIUrl":"https://doi.org/10.1007/s11282-024-00740-y","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objective</h3><p>This systematic review was performed to examine the usefulness of salivary gland ultrasound elastography (USE) as a diagnostic tool for Sjögren’s syndrome (SjS).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>Electronic databases (MEDLINE, EMBASE, the Cochrane Library, and Web of Science: Science Citation Index) were searched to identify studies using USE to diagnose SjS from database inception to 15 July 2022. The primary outcome was improved diagnostic accuracy for SjS with the use of USE. Risk of bias and applicability concerns were assessed using the GRADE system, which is continuously developed by the GRADE Working Group.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Among 4550 screened studies, 24 full-text articles describing the applications of USE to diagnose SjS were reviewed. The overall risk of bias was determined to be low for 17 of the 24 articles, medium for 5, and high for 2. Articles comparing patients with SjS and healthy subjects reported high diagnostic accuracy of USE, with most results showed statistically significant differences (parotid glands: 15 of the 16 articles, submandibular glands: 11 of the 14 articles).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>This systematic review suggests that the assessment of salivary glands using USE is a useful diagnostic tool for SjS.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139679076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative assessment of cleft volume and evaluation of cleft’s impact on adjacent anatomical structures using CBCT imaging","authors":"António Vicente, Anna-Paulina Wiedel, Magnus Becker, Susanne Brogårdh-Roth, Xie-Qi Shi, Kristina Hellén-Halme","doi":"10.1007/s11282-023-00736-0","DOIUrl":"https://doi.org/10.1007/s11282-023-00736-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Objectives</h3><p>To determine pre-operative cleft volume and evaluate cleft´s impact on surrounding anatomical structures in children and adolescents with orofacial clefts using cone bean computed tomography (CBCT) imaging.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>The present retrospective study retrieved CBCT examinations of 68 patients from a previous study. The examinations had been exposed either before (<i>n</i> = 53) or after (<i>n</i> = 15) alveolar bone grafting. Pre-operative volume of cleft was determined, and type and location were evaluated. Morphological changes on the adjacent anatomical structures, including the incisive foramen, the nasal septum and floor, and the inferior turbinate, were assessed.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Mean bilateral cleft volume was 0.76 cm<sup>3</sup>, while mean unilateral cleft volume was 1.08 cm<sup>3</sup>; the difference was significant (<i>p</i> < 0.001). Variation in cleft volume, however, was large. The incisive foramen was not visible in the majority of cases with bilateral clefts (71%); the difference was significant (<i>p</i> = 0.001). In cases with unilateral clefts, the nasal septum in 87% was curved towards the cleft or graft side. Also, the mean size of the widest part of the inferior turbinate was 8.8 mm on the cleft or graft side and 10.4 mm on the non-cleft side. The difference was significant (<i>p</i> < 0.001).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>When required, CBCT is a feasible method for quantitatively illustrating alveolar clefts and their impact on the morphological development of surrounding structures. Variation in cleft volume was large.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139663088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging findings of orofacial cysticercosis: report of 5 cases with review of literature.","authors":"Shikha Gupta, Sunita Gupta, Ridam Sharma, Sujoy Ghosh, Jyoti Kumar, Abhishek Jha","doi":"10.1007/s11282-022-00651-w","DOIUrl":"10.1007/s11282-022-00651-w","url":null,"abstract":"<p><p>Cysticercosis, a fatal disease of parasitic aetiology seen in humans, is caused by ingestion of larvae of Taenia solium in form of raw or poorly cooked pork. Commonly seen in developing countries, it affects the brain, muscle, lungs, heart and liver and is rarely found in the maxillofacial region. Sometimes, the only evidence of cysticercosis could be the cystic swellings or nodules in the maxillofacial region. Such solitary clinical presentation can be diagnosed early with the aid of ultrasound (USG) and Magnetic resonance imaging (MRI). Here, we present 5 cases of intramuscular cysticercosis of Orofacial region which were initially diagnosed on ultrasonography and later confirmed by MRI and aspiration cytology. We have conducted a systematic review of PubMed Literature for Intramuscular cysticercosis of orofacial region and highlighted key imaging findings from 18 cases retrieved. Through this case series, we highlight the USG and MRI imaging features of intramuscular cysticercosis which are characteristic and diagnostic of the condition.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40353848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-COVID mucormycosis osteomyelitis and its imaging manifestations in the North of Iran: case series.","authors":"Safa Motevasseli, Ali Nazarpour, Zahra Dalili Kajan, Zahra Yousefi, Negar Khosravifard, Faezeh Kashi, Niousha Roudbari","doi":"10.1007/s11282-022-00650-x","DOIUrl":"10.1007/s11282-022-00650-x","url":null,"abstract":"<p><p>Mucormycosis is an invasive fungal infection that usually affects patients with immunocompromised conditions. In the context of the COVID-19 pandemic and the following corticosteroid therapy, mucormycosis prevalence has increased. The situation may be more complicated with some underlying diseases such as diabetes mellitus. In addition, due to the vicinity of maxillary bone to the nasal cavity and paranasal sinuses, which are the main routes for the infection to spread, dentists, maxillofacial radiologists, and surgeons may be the first to encounter these patients. Post-COVID mucormycosis osteomyelitis is one of the complications of this infection Bone destruction and the erosion or breach of cortical boundaries of the maxilla and the bone structures in the vicinity of paranasal sinuses are the most critical radiographic findings of post-covid osteomyelitis. Herein, there are some cases of post-covid mucormycosis osteomyelitis involving the maxillary and other facial bones.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40351298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2024-01-01Epub Date: 2023-02-11DOI: 10.1007/s11282-023-00672-z
Ming Hong Jim Pun
{"title":"Comment on \"Deep-learning approach for caries detection and segmentation on dental bitewing radiographs.\"","authors":"Ming Hong Jim Pun","doi":"10.1007/s11282-023-00672-z","DOIUrl":"10.1007/s11282-023-00672-z","url":null,"abstract":"","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10747561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Five-year change of panoramic radiomorphometric indices and fractal dimension values in type 2 diabetes patients.","authors":"Numan Dedeoğlu, Gözde Eşer, Duygu Çelik Özen, Oğuzhan Altun","doi":"10.1007/s11282-023-00707-5","DOIUrl":"10.1007/s11282-023-00707-5","url":null,"abstract":"<p><strong>Objectives: </strong>Diabetes mellitus is a chronic disease characterized by dysregulation of glucose metabolism, with characteristic long-term complications accompanied by changes in bone quality. The purpose of this study is to compare the results with a control group by performing radiomorphometric analyses on panoramic radiographs obtained 5 years apart to examine changes in the mandibular bone cortex and microstructures of type 2 diabetes mellitus (T2DM) patients.</p><p><strong>Methods: </strong>Two panoramic radiographs that were taken 5 years (mean 5.26 ± 0.134) apart from 52 patients with T2DM (n:26) and a control group (n:26) were used. A total of 104 images were evaluated. Analyses were done from the condyle (FD1), angulus (FD2), distal second premolar apex (FD3), and anterior to the mental foramen (FD4) for fractal dimension (FD) in the mandible. Symphysis index (SI), anterior index (AI), molar index (MI), posterior index (PI), and panoramic mandibular index (PMI) measurements were taken for cortical analysis. Three-way ANOVA, three-way robust ANOVA, two-way ANOVA, and two-way robust ANOVA tests were used for statistical analysis (p < 0.05).</p><p><strong>Results: </strong>After a 5-year period, there was a significant decrease in all FD measures of the mandible in both T2DM and control groups (p < 0.05). This resulted in a statistical difference in the main effect of time. After a 5-year period, no significant difference in mandibular cortical measures was identified between the T2DM and control groups (p > 0.05).</p><p><strong>Conclusion: </strong>According to panoramic radiography, the mandibular trabecular structure deteriorated after 5 years, whereas cortical values remained the same. It concluded that T2DM had no effect on these results.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10052785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2024-01-01Epub Date: 2023-08-04DOI: 10.1007/s11282-023-00703-9
Cyntia Adames, Hugo Gaêta-Araujo, Ademir Franco, Mariana Quirino Silveira Soares, José Luiz Cintra Junqueira, Anne Caroline Oenning
{"title":"Influence of CBCT-derived panoramic curve variability in the measurements for dental implant planning.","authors":"Cyntia Adames, Hugo Gaêta-Araujo, Ademir Franco, Mariana Quirino Silveira Soares, José Luiz Cintra Junqueira, Anne Caroline Oenning","doi":"10.1007/s11282-023-00703-9","DOIUrl":"10.1007/s11282-023-00703-9","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether the curve markings performed prior to panoramic and cross-sectional reconstructions can influence the planning of oral implants.</p><p><strong>Methods: </strong>Twenty oral radiologists landmarked the reference panoramic curves in 25 CBCT scans of the mandible. Bone height was measured on the resulting cross-sectional slices in the edentulous region of the lower first molar. The following data were recorded: (1) number of landmarks used to build each reference curve; (2) shape of the reference curve (inverted \"U\", inverted \"V\" or \"horseshoe\"); and (3) measurement in the first molar region. The data were assessed for variability based on the number of landmarks, the shape of the reference curve, and the measurements obtained.</p><p><strong>Results: </strong>The number of landmarks used to guide the panoramic reconstruction varied among radiologists (p < 0.05), but most of them draw curves in inverted \"U\" shape (68-100%). The reproducibility of the measurements taken in the edentulous mandibular first molar region was excellent (84.7%). The number of landmarks and the shape of the curve did not have a significant influence on the reproducibility of the measurements (p > 0.05).</p><p><strong>Conclusion: </strong>Variations of the operator-dependent steps during the panoramic reconstructions occur but do not play a significant part changing the measurements taken for oral implant planning.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9931977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral RadiologyPub Date : 2024-01-01Epub Date: 2023-09-29DOI: 10.1007/s11282-023-00710-w
Xiaoxu Fang, Hong Ding, Cunhui Fan, Lei Pang, Tao Xu, Jialin Liu, Chunmiao Jiang
{"title":"Comparison of mandibular buccal shelf morphology between adolescents and adults with different vertical patterns using CBCT.","authors":"Xiaoxu Fang, Hong Ding, Cunhui Fan, Lei Pang, Tao Xu, Jialin Liu, Chunmiao Jiang","doi":"10.1007/s11282-023-00710-w","DOIUrl":"10.1007/s11282-023-00710-w","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective study aimed to analyze the anatomical structure of the mandibular buccal shelf (MBS) in adolescents and adults with different vertical patterns to determine the optimal location for miniscrew insertion in orthodontic treatment.</p><p><strong>Methods: </strong>Cone-beam computed tomography (CBCT) scans of 230 patients were utilized for measurements. The morphology and thickness of alveolar bone at the MBS were measured. Two-way ANOVA and regression analysis were conducted to analyze the influencing factors on alveolar bone and cortical bone thickness.</p><p><strong>Results: </strong>Age had a significant effect on alveolar bone thickness (level I: F = 62.449, level II: F = 18.86, p < 0.001), cortical bone thickness (level II: F = 18.86, p < 0.001), alveolar bone tilt (F = 6.267, p = 0.013), and second molar tilt (F = 6.693, p = 0.01). Different vertical patterns also influenced alveolar bone thickness (level I: F = 20.950, level II: F = 28.470, p < 0.001), cortical bone thickness (level I: F = 23.911, level II: F = 23.370, p < 0.001), and alveolar bone tilt (F = 27.046, p < 0.001). As age increased, the alveolar bone thickness at level I decreased by 0.096 mm and at level II decreased by 0.073 mm. Conversely, the thickness of alveolar bone at level I and level II increased by 0.06 mm and 0.075 mm, respectively. The cortical bone thickness at level I and level II increased by 0.024 mm and 0.29 mm, respectively. However, the alveolar bone thickness decreased by 0.931 mm and 1.545 mm at level I and level II, and the cortical bone thickness decreased by 0.542 mm and 0.640 mm at level I and level II, respectively.</p><p><strong>Conclusion: </strong>Age, different vertical patterns, alveolar bone inclination, and different shapes of MBS significantly affected the thickness of alveolar bone and cortical bone in the MBS area. Notably, only alveolar bone thickness and cortical bone thickness at level II were affected by age and different vertical patterns simultaneously. These findings can provide valuable insights for orthodontic practitioners in selecting the most suitable location for miniscrew insertion during treatment planning.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41124013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep learning for diagnosis of head and neck cancers through radiographic data: a systematic review and meta-analysis.","authors":"Rata Rokhshad, Seyyede Niloufar Salehi, Amirmohammad Yavari, Parnian Shobeiri, Mahdieh Esmaeili, Nisha Manila, Saeed Reza Motamedian, Hossein Mohammad-Rahimi","doi":"10.1007/s11282-023-00715-5","DOIUrl":"10.1007/s11282-023-00715-5","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to review deep learning applications for detecting head and neck cancer (HNC) using magnetic resonance imaging (MRI) and radiographic data.</p><p><strong>Methods: </strong>Through January 2023, a PubMed, Scopus, Embase, Google Scholar, IEEE, and arXiv search were carried out. The inclusion criteria were implementing head and neck medical images (computed tomography (CT), positron emission tomography (PET), MRI, Planar scans, and panoramic X-ray) of human subjects with segmentation, object detection, and classification deep learning models for head and neck cancers. The risk of bias was rated with the quality assessment of diagnostic accuracy studies (QUADAS-2) tool. For the meta-analysis diagnostic odds ratio (DOR) was calculated. Deeks' funnel plot was used to assess publication bias. MIDAS and Metandi packages were used to analyze diagnostic test accuracy in STATA.</p><p><strong>Results: </strong>From 1967 studies, 32 were found eligible after the search and screening procedures. According to the QUADAS-2 tool, 7 included studies had a low risk of bias for all domains. According to the results of all included studies, the accuracy varied from 82.6 to 100%. Additionally, specificity ranged from 66.6 to 90.1%, sensitivity from 74 to 99.68%. Fourteen studies that provided sufficient data were included for meta-analysis. The pooled sensitivity was 90% (95% CI 0.820.94), and the pooled specificity was 92% (CI 95% 0.87-0.96). The DORs were 103 (27-251). Publication bias was not detected based on the p-value of 0.75 in the meta-analysis.</p><p><strong>Conclusion: </strong>With a head and neck screening deep learning model, detectable screening processes can be enhanced with high specificity and sensitivity.</p>","PeriodicalId":56103,"journal":{"name":"Oral Radiology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}