Journal of Nippon Medical School最新文献_第2页

Familial Congenital Ossicular Anomaly: A Case Report. 家族性先天性听骨异常1例报告。

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-10 Epub Date: 2025-03-22 DOI: 10.1272/jnms.JNMS.2025_92-606

Takeshi Matsunobu, Hirotaka Suzuki, Kimihiro Okubo

引用次数: 0

Circulatory Management with Impella Assistance during Off-Pump Coronary Artery Bypass Grafting for Cardiogenic Shock: A Report of Two Cases. 心源性休克非体外循环冠状动脉旁路移植术中叶轮辅助循环管理2例报告。

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-10 Epub Date: 2025-06-26 DOI: 10.1272/jnms.JNMS.2025_92-609

Makiko Yamamoto, Yuka Ino, Keisuke Mori, Yuji Maruyama, Yosuke Ishii, Masashi Ishikawa, Atsuhiro Sakamoto

{"title":"Circulatory Management with Impella Assistance during Off-Pump Coronary Artery Bypass Grafting for Cardiogenic Shock: A Report of Two Cases.","authors":"Makiko Yamamoto, Yuka Ino, Keisuke Mori, Yuji Maruyama, Yosuke Ishii, Masashi Ishikawa, Atsuhiro Sakamoto","doi":"10.1272/jnms.JNMS.2025_92-609","DOIUrl":"10.1272/jnms.JNMS.2025_92-609","url":null,"abstract":"The combination of initial Impella therapy, Impella-supported coronary artery bypass grafting (ISCAB), and postoperative Impella therapy providing antegrade perfusion in myocardial infarction can prove effective. We investigated strategies for Impella stabilization in ISCAB, particularly during peripheral circumflex branch anastomosis. Case 1 was a 70-year-old man treated with an Impella 2.5, followed by urgent ISCAB on the day of hospitalization, for a left main trunk lesion. Use of an apical suction device to position the heart to expose an obtuse marginal branch caused Impella obstruction by applying suction to the left ventricular wall, interrupting revascularization; however, one revascularization was achieved. Case 2 was a 79-year-old man treated with an Impella CP for a three-vessel lesion until ISCAB 4 days later. The Impella was stabilized with appropriate positioning by adjusting the bed angle, minimal heart compression with a deep pericardial stitch without pulling on the cardiac apex, and sufficient preload, even during posterolateral branch anastomosis. Four revascularizations were eventually achieved. Multiple innovations to prevent Impella contact with the left ventricle as described herein improve ISCAB safety, particularly during peripheral circumflex branch anastomosis.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":" ","pages":"474-479"},"PeriodicalIF":1.4,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microtia with Coexistent Large External Auditory Canal Cholesteatoma: A Case Report. 小耳畸形合并大外耳道胆脂瘤1例。

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-10 Epub Date: 2025-03-22 DOI: 10.1272/jnms.JNMS.2025_92-608

Takeshi Matsunobu, Hirotaka Suzuki, Naoko Sakuma, Ryuji Ohashi, Kimihiro Okubo

{"title":"Microtia with Coexistent Large External Auditory Canal Cholesteatoma: A Case Report.","authors":"Takeshi Matsunobu, Hirotaka Suzuki, Naoko Sakuma, Ryuji Ohashi, Kimihiro Okubo","doi":"10.1272/jnms.JNMS.2025_92-608","DOIUrl":"10.1272/jnms.JNMS.2025_92-608","url":null,"abstract":"Microtia is a congenital disorder characterized by an anomaly in the auricle. It is often associated with atresia, stenosis, or obstruction of the external auditory canal. In cases of microtia, the incidence of a normal external auditory canal, congenital external auditory canal stenosis, and congenital complete closure of the external auditory canal (aural atresia) is reported to be 8%, 8%, and 84%, respectively. Congenital stenosis of the external auditory canal can sometimes be accompanied by intractable otorrhea and otalgia, raising the possibility of complications of external auditory canal cholesteatoma. Here, we report a case of an adult with microtia and external auditory canal stenosis who presented to our clinic with complaints of otalgia. A large external auditory canal cholesteatoma was found in the patient's left ear. Although cholesteatoma is common in cases of canal stenosis, its extensive spread within the temporal bone is quite rare. A temporal bone-targeted computed tomography scan revealed a soft tissue shadow in the left external auditory canal with distensible expansion and bony destruction in the upper, anterior, and posterior walls of the external auditory canal. In patients with microtia who experience severe aural pain, the possibility of latent extended cholesteatoma should be considered.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":" ","pages":"468-473"},"PeriodicalIF":1.4,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vagal Reflex-Induced Asystole during Suspension Laryngoscopy: A Rare Complication. 悬吊喉镜检查时迷走神经反射引起的心脏收缩：一种罕见的并发症。

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-10 Epub Date: 2025-03-22 DOI: 10.1272/jnms.JNMS.2025_92-604

Takeshi Matsunobu, Kimihiro Okubo, Koichiro Saito

{"title":"Vagal Reflex-Induced Asystole during Suspension Laryngoscopy: A Rare Complication.","authors":"Takeshi Matsunobu, Kimihiro Okubo, Koichiro Saito","doi":"10.1272/jnms.JNMS.2025_92-604","DOIUrl":"10.1272/jnms.JNMS.2025_92-604","url":null,"abstract":"Suspension laryngoscopy is commonly used in diagnostic and operative procedures involving the larynx. This study presents a rare case of asystole during suspension laryngoscopy. A 58-year-old woman with an unremarkable medical history underwent suspension laryngoscopy for a left polypoid vocal cord under general anesthesia. Anesthesia induction and tracheal intubation were performed without complications. However, upon inserting a direct laryngoscope and exposing the larynx, her heart rate gradually decreased and asystole occurred. The direct laryngoscope was immediately removed, and atropine sulfate was injected. Spontaneous circulation was restored after 20 s of asystole. The direct laryngoscope was then re-inserted, and the operation was successfully completed without complications. Asystole was attributed to stimulation of the pharyngolaryngeal mucosa through direct laryngoscope-induced vagal reflex. This case highlights the need for surgeons and anesthesiologists to be aware of this rare but potentially life-threatening complication and emphasizes the importance of vigilant electrocardiography monitoring during direct laryngoscope adjustment.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":" ","pages":"446-449"},"PeriodicalIF":1.4,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of Sialendoscopy to Diagnose Sialodochitis Fibrinosa: A Case Report. 用鼻内窥镜诊断纤维性涎腺支气管炎1例。

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-10 Epub Date: 2025-03-22 DOI: 10.1272/jnms.JNMS.2025_92-603

Takeshi Matsunobu, Hirotaka Suzuki, Akira Shimizu, Koji Sakamoto, Kimihiro Okubo

{"title":"Use of Sialendoscopy to Diagnose Sialodochitis Fibrinosa: A Case Report.","authors":"Takeshi Matsunobu, Hirotaka Suzuki, Akira Shimizu, Koji Sakamoto, Kimihiro Okubo","doi":"10.1272/jnms.JNMS.2025_92-603","DOIUrl":"10.1272/jnms.JNMS.2025_92-603","url":null,"abstract":"First reported by Kussmaul in 1879, sialodochitis fibrinosa is a disease of the parotid and/or submandibular glands that is characterized by pain and diffuse swelling. It is believed to be caused by obstruction of the salivary duct by mucofibrinous plugs and is often misdiagnosed as other types of sialadenitis, such as Sjögren's syndrome, or sialadenitis caused by bacterial or viral infection. Although specific diagnostic criteria have not been defined, the typical pathological finding of sialodochitis fibrinosa is infiltration of lymphocytes and eosinophils into the interstitium around the salivary ducts. Sialendoscopy, a minimally invasive endoscopic technique, has recently been used to diagnose and treat diseases of the salivary glands. This new technique can be used to irrigate and dilate the salivary gland ducts under direct vision. We successfully used sialendoscopy to diagnose and treat sialodochitis fibrinosa, making this the first reported use of this technique for salivary gland biopsies. Sialendoscopy is a modern approach to salivary gland disorders that was helpful for understanding, diagnosing, and managing sialodochitis fibrinosa.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":" ","pages":"440-445"},"PeriodicalIF":1.4,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Video-Assisted Thoracoscopic Surgery for Catamenial Pneumothorax: A Report of Five Cases Treated by Diaphragm Reefing with and without Chemical Pleurodesis. 电视胸腔镜手术治疗双膜性气胸：附或不附化学胸膜切除术的横膈膜冷冻术5例报告。

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-10 Epub Date: 2025-03-22 DOI: 10.1272/jnms.JNMS.2025_92-607

Hirotoshi Kubokura, Yuuya Tomioka, Junichi Okamoto, Naoyuki Yoshino, Jitsuo Usuda

{"title":"Video-Assisted Thoracoscopic Surgery for Catamenial Pneumothorax: A Report of Five Cases Treated by Diaphragm Reefing with and without Chemical Pleurodesis.","authors":"Hirotoshi Kubokura, Yuuya Tomioka, Junichi Okamoto, Naoyuki Yoshino, Jitsuo Usuda","doi":"10.1272/jnms.JNMS.2025_92-607","DOIUrl":"10.1272/jnms.JNMS.2025_92-607","url":null,"abstract":"Background: Catamenial pneumothorax (CP), the most common manifestation of thoracic endometriosis syndrome, is a rare form of primary spontaneous pneumothorax that occurs in women of reproductive age. Although CP is usually treated surgically or with hormonal therapy, there is no standard treatment and recurrence is common. We performed video-assisted thoracoscopic surgery (VATS) for five patients with CP from 2014 to 2023.Methods: Our surgical basic procedure (BP) was as follows. VATS was performed by using one port site for the camera and a 5-cm mini-thoracotomy. Perforated holes or blueberry spots were detected on the diaphragm, and lesions were ligated with an endoscopic loop. After reefing by ligation, the diaphragm was covered with a polyglycolic acid sheet. Three methods were used: (A) BP only (one case); (B) BP with tetracycline plus OK432 (two cases); (C) BP with tetracycline (two cases); because the use of OK432 (an anti-cancer agent) was disallowed in 2019 in our Institutional Review Board rules for patients with benign disease.Results: Age ranged from 33 to 45 years (mean, 38.6±5.1 years), and CP occurred on the right side in all cases. Recurrence occurred in only two of the five cases (one case each for procedures B and C).Conclusion: Our procedure (diaphragm reefing by ligation and covering with a polyglycolic acid sheet) was a more convenient and more effective treatment for CP.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":" ","pages":"463-467"},"PeriodicalIF":1.4,"publicationDate":"2026-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Comment on "Predictive Postoperative Inflammatory Response Indicators of Infectious Complications Following Gastrectomy for Gastric Cancer". 对“胃癌胃切除术后感染性并发症的预测炎性反应指标”评论的回应

IF 1.4 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-01 DOI: 10.1272/jnms.JNMS.2026_93-105

Ryohei Nishiguchi

引用次数: 0

A Guide to Sublingual Immunotherapy in Japan. 日本舌下免疫治疗指南。

IF 1.8 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-01 DOI: 10.1272/jnms.JNMS.2026_93-312

Minoru Gotoh

引用次数: 0

Variations in the Formation of Lamellar Macular Hole through Epiretinal Membrane, Macular Pseudohole, and ERM-Foveoschisis. 通过视网膜前膜、黄斑假孔和erm - fovesch裂孔形成片层黄斑孔的变化。

IF 1.8 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-01 DOI: 10.1272/jnms.JNMS.2026_93-306

Noriko Kubota, Yosai Mori, Kazunori Miyata, Yuji Nakano, Hitoshi Goto, Tomoyuki Kunishige, Fumiki Okamoto

{"title":"Variations in the Formation of Lamellar Macular Hole through Epiretinal Membrane, Macular Pseudohole, and ERM-Foveoschisis.","authors":"Noriko Kubota, Yosai Mori, Kazunori Miyata, Yuji Nakano, Hitoshi Goto, Tomoyuki Kunishige, Fumiki Okamoto","doi":"10.1272/jnms.JNMS.2026_93-306","DOIUrl":"https://doi.org/10.1272/jnms.JNMS.2026_93-306","url":null,"abstract":"Purpose: To investigate morphological changes associated with lamellar macular hole (LMH).Methods: We retrospectively reviewed data for all eyes with LMH, as determined by spectral-domain optical coherence tomography (OCT), from patients who had undergone vitrectomy and had at least 12 months of preoperative and 6 months of postoperative follow-up data. Eyes were classified as those with morphological changes in the epiretinal membrane (ERM), macular pseudohole (MPH), or ERM-foveoschisis (ERM-FS) that were observed before LMH formation (group A), and those in which LMH was present at the first visit and remained unchanged until surgery (group B). Follow-up time (from first visit to surgery), time from detection of diseases associated with LMH, and morphological changes were analyzed.Results: Of 14 eyes of 14 patients, 9 were in group A and 5 were in group B, and mean follow-up time was 49.2 ± 23.5 months and 44.4 ± 25.4 months in groups A and B, respectively. In group A, LMH formed through ERM in 1 eye, MPH in 2 eyes, and ERM-FS in 6 eyes; 5 eyes maintained LMH morphology for longer than 12 months. The mean time from associated disease to LMH was 11.2 ± 13.8 months, and 30.3 ± 25.5 months from LMH to surgery. BCVA significantly improved in group A (p<0.05) but not in group B (p=0.0579). Neither time to surgery in group A nor follow-up time correlated with postoperative BCVA.Conclusion: LMH likely forms through progression of associated diseases, and time from LMH to surgery was not significantly associated with visual outcomes.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"93 3","pages":"218-224"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148347601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Clinical Feasibility of Magnetic Sentinel Lymph Node Biopsy with Resovist and the Radioisotope Method for Breast Cancer. 乳腺癌磁前哨淋巴结活检与放射性同位素法的临床可行性比较。

IF 1.8 4区医学

Journal of Nippon Medical School Pub Date : 2026-01-01 DOI: 10.1272/jnms.JNMS.2026_93-113

Keiko Yanagihara, Tamami Yamakawa, Sena Kato, Miki Tamura, Koji Nagata

{"title":"Comparison of Clinical Feasibility of Magnetic Sentinel Lymph Node Biopsy with Resovist and the Radioisotope Method for Breast Cancer.","authors":"Keiko Yanagihara, Tamami Yamakawa, Sena Kato, Miki Tamura, Koji Nagata","doi":"10.1272/jnms.JNMS.2026_93-113","DOIUrl":"10.1272/jnms.JNMS.2026_93-113","url":null,"abstract":"Background: Sentinel lymph node biopsy (SLNB) is the standard procedure for axillary staging in early breast cancer. Although the radioisotope (RI) method is highly accurate, it requires nuclear medicine facilities and exposes patients to radiation. Superparamagnetic iron oxide (SPIO) tracers were shown to be noninferior to RI in trials outside Japan but are not approved in Japan. Resovist (ferucarbotran), an MRI contrast agent containing SPIO, may be an alternative. This study compared the feasibility and diagnostic performance of Resovist-based magnetic SLNB with the RI method.Methods: This paired study analyzed 27 breast cancer cases treated with both RI-based and Resovist-based magnetic SLNB. Resovist 0.8 mL was injected subcutaneously above the tumor or into the periareolar region, and the site was gently massaged. The injection-site skin and subcutaneous tissue were excised to prevent pigmentation. Identification rates were assessed at the patient and node levels, and subgroup analysis of patients stratified by body mass index (BMI <25 vs. ≥25) was performed. McNemar's and Fisher's exact tests were used.Results: SLN identification was 100% (27/27 patients) for RI and 88.9% (24/27) for the magnetic method. Among 49 nodes, the results were RI+/Mag+ for 34, RI+/Mag- for 6, and RI-/Mag+ for 9, yielding detection rates of 81.6% (RI) and 87.8% (magnetic). No allergic reactions, pigmentation, or injection site complications occurred. BMI had no significant effect (p > 0.05).Conclusions: Resovist-based magnetic SLNB was feasible and safe, and had detection rates comparable to those of RI. Optimization of injection conditions may further improve accuracy.","PeriodicalId":56076,"journal":{"name":"Journal of Nippon Medical School","volume":"93 1","pages":"67-71"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0