Pain in Soft Tissue Tumors: A Comprehensive Retrospective Study.

IF 1.4 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Journal of Nippon Medical School Pub Date : 2025-01-01 DOI:10.1272/jnms.JNMS.2025_92-113

Yasuyuki Kitagawa, Kazuma Miura, Daisuke Fukuhara, Naoto Kotani, Shoko Sasaki, Yosuke Shinozuka, Tokifumi Majima

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引用次数: 0

Abstract

Background: In the field of orthopedics, few studies have examined pain associated with soft tissue tumors. To accurately and promptly diagnose soft tissue tumors and provide appropriate treatment, it is necessary to have a comprehensive understanding of the relationship between soft tissue tumors and pain.

Methods: We analyzed data from patients with mass lesions in the extremities or trunk diagnosed by biopsy or surgery in our department and patients with ganglion cysts diagnosed by puncture between October 1, 2005, and September 30, 2011. Using medical records, we retrospectively investigated the clinical data.

Results: Data from 473 patients with 482 lesions were analyzed. Pain was observed in 204 of the 482 lesions (42.3%). So-called painful tumors accounted for approximately half of the painful lesions (45.0%). Logistic regression indicated that pain was significantly associated with so-called painful tumors (odds ratio [OR]: 5.64; P < 0.001), inflammatory nodules (OR: 3.42; P = 0.007), and sites with strong physical stimulation (OR: 2.45; 95% confidence interval [CI]: 1.58-3.81; P < 0.001) but not with long diameter (OR: 0.90; P = 0.001) or malignancy (OR: 1.78; P = 0.144).

Conclusion: Our findings suggest that so-called painful tumors account for approximately half of soft tissue mass lesions requiring surgery, biopsy, or puncture in orthopedics. It is thus important to have a clear understanding of such tumors. Inflammatory nodules are also important in the differential diagnosis of painful soft tissue lesions. Lesions at sites exposed to strong physical stimulation can cause pain.

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软组织肿瘤疼痛：一项全面的回顾性研究。

背景：在骨科领域，很少有研究检查与软组织肿瘤相关的疼痛。为了准确、及时地诊断软组织肿瘤并提供适当的治疗，有必要全面了解软组织肿瘤与疼痛的关系。方法：我们分析了2005年10月1日至2011年9月30日期间我科活检或手术诊断的四肢或躯干肿块病变患者和穿刺诊断的神经节囊肿患者的资料。利用医疗记录，我们回顾性地调查了临床资料。结果：分析了473例患者482个病变的数据。482个病变中有204个（42.3%）出现疼痛。所谓的疼痛性肿瘤约占疼痛性病变的一半（45.0%）。Logistic回归显示疼痛与所谓的疼痛性肿瘤显著相关(比值比[OR]: 5.64；P < 0.001)，炎性结节(OR: 3.42；P = 0.007)，强物理刺激部位(OR: 2.45；95%置信区间[CI]: 1.58-3.81；P < 0.001)，但与长径无关(OR: 0.90；P = 0.001)或恶性肿瘤(or: 1.78；P = 0.144)。结论：我们的研究结果表明，所谓的疼痛肿瘤约占骨科中需要手术、活检或穿刺的软组织肿块病变的一半。因此，对这类肿瘤有一个清晰的认识是很重要的。炎性结节在疼痛性软组织病变的鉴别诊断中也很重要。受到强烈物理刺激的部位的病变会引起疼痛。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Nippon Medical School MEDICINE, GENERAL & INTERNAL-

CiteScore

1.80

自引率

10.00%

发文量

118

期刊介绍： The international effort to understand, treat and control disease involve clinicians and researchers from many medical and biological science disciplines. The Journal of Nippon Medical School (JNMS) is the official journal of the Medical Association of Nippon Medical School and is dedicated to furthering international exchange of medical science experience and opinion. It provides an international forum for researchers in the fields of bascic and clinical medicine to introduce, discuss and exchange thier novel achievements in biomedical science and a platform for the worldwide dissemination and steering of biomedical knowledge for the benefit of human health and welfare. Properly reasoned discussions disciplined by appropriate references to existing bodies of knowledge or aimed at motivating the creation of such knowledge is the aim of the journal.