Journal of Gastric Cancer最新文献

筛选
英文 中文
Safe Discharge Criteria After Curative Gastrectomy for Gastric Cancer. 胃癌根治性胃切除术后安全出院标准。
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-10-01 DOI: 10.5230/jgc.2022.22.e32
Ali Guner, Ki Yoon Kim, Sung Hyun Park, Minah Cho, Yoo Min Kim, Woo Jin Hyung, Hyoung-Il Kim
{"title":"Safe Discharge Criteria After Curative Gastrectomy for Gastric Cancer.","authors":"Ali Guner,&nbsp;Ki Yoon Kim,&nbsp;Sung Hyun Park,&nbsp;Minah Cho,&nbsp;Yoo Min Kim,&nbsp;Woo Jin Hyung,&nbsp;Hyoung-Il Kim","doi":"10.5230/jgc.2022.22.e32","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e32","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the relationship between clinical and laboratory parameters and complication status to predict which patients can be safely discharged from the hospital on the third postoperative day (POD).</p><p><strong>Materials and methods: </strong>Data from a prospectively maintained database of 2,110 consecutive patients with gastric adenocarcinoma who underwent curative surgery were reviewed. The third POD vital signs, laboratory data, and details of the course after surgery were collected. Patients with grade II or higher complications after the third POD were considered unsuitable for early discharge. The performance metrics were calculated for all algorithm parameters. The proposed algorithm was tested using a validation dataset of consecutive patients from the same center.</p><p><strong>Results: </strong>Of 1,438 patients in the study cohort, 142 (9.9%) were considered unsuitable for early discharge. C-reactive protein level, body temperature, pulse rate, and neutrophil count had good performance metrics and were determined to be independent prognostic factors. An algorithm consisting of these 4 parameters had a negative predictive value (NPV) of 95.9% (95% confidence interval [CI], 94.2-97.3), sensitivity of 80.3% (95% CI, 72.8-86.5), and specificity of 51.1% (95% CI, 48.3-53.8). Only 28 (1.9%) patients in the study cohort were classified as false negatives. In the validation dataset, the NPV was 93.7%, sensitivity was 66%, and 3.3% (17/512) of patients were classified as false negatives.</p><p><strong>Conclusions: </strong>Simple clinical and laboratory parameters obtained on the third POD can be used when making decisions regarding the safe early discharge of patients who underwent gastrectomy.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/07/jgc-22-395.PMC9633928.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40657427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Clinical Impact of Advanced Age on the Postoperative Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Analysis Across US Hospitals Between 2011-2017. 高龄对胃癌胃切除术患者术后结局的临床影响:2011-2017年美国医院分析
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e18
David Uihwan Lee, Gregory Hongyuan Fan, Kevin Chang, Ki Jung Lee, John Han, Daniel Jung, Jean Kwon, Raffi Karagozian
{"title":"The Clinical Impact of Advanced Age on the Postoperative Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Analysis Across US Hospitals Between 2011-2017.","authors":"David Uihwan Lee,&nbsp;Gregory Hongyuan Fan,&nbsp;Kevin Chang,&nbsp;Ki Jung Lee,&nbsp;John Han,&nbsp;Daniel Jung,&nbsp;Jean Kwon,&nbsp;Raffi Karagozian","doi":"10.5230/jgc.2022.22.e18","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e18","url":null,"abstract":"<p><strong>Purpose: </strong>This study systematically evaluated the implications of advanced age on post-surgical outcomes following gastrectomy for gastric cancer using a national database.</p><p><strong>Materials and methods: </strong>The 2011-2017 National Inpatient Sample was used to isolate patients who underwent gastrectomy for gastric cancer. From this, the population was stratified into those belonging to the younger age cohort (18-59 years), sexagenarians, septuagenarians, and octogenarians. The younger cohort and each advanced age category were compared in terms of the following endpoints: mortality following surgery, length of hospital stay, charges, and surgical complications.</p><p><strong>Results: </strong>This study included a total of 5,213 patients: 1,366 sexagenarians, 1,490 septuagenarians, 743 octogenarians, and 1,614 under 60 years of age. Between the younger cohort and sexagenarians, there was no difference in mortality (2.27 vs. 1.67%; P=0.30; odds ratio [OR], 1.36; 95% confidence interval [CI], 0.81-2.30), length of stay (11.0 vs. 11.1 days; P=0.86), or charges ($123,557 vs. $124,425; P=0.79). Compared to the younger cohort, septuagenarians had higher rates of in-hospital mortality (4.30% vs. 1.67%; P<0.01; OR, 2.64; 95% CI, 1.67-4.16), length of stay (12.1 vs. 11.1 days; P<0.01), and charges ($139,200 vs. $124,425; P<0.01). In the multivariate analysis, septuagenarians had higher mortality (P=0.01; adjusted odds ratio [aOR], 2.01; 95% CI, 1.18-3.43). Similarly, compared to the younger cohort, octogenarians had a higher rate of mortality (7.67% vs. 1.67%; P<0.001; OR, 4.88; 95% CI, 3.06-7.79), length of stay (12.3 vs. 11.1 days; P<0.01), and charges ($131,330 vs. $124,425; P<0.01). In the multivariate analysis, octogenarians had higher mortality (P<0.001; aOR, 4.03; 95% CI, 2.28-7.11).</p><p><strong>Conclusions: </strong>Advanced age (>70 years) is an independent risk factor for postoperative death in patients with gastric cancer undergoing gastrectomy.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/33/jgc-22-197.PMC9359884.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Postoperative Complications and Their Risk Factors of Completion Total Gastrectomy for Remnant Gastric Cancer Following an Initial Gastrectomy for Cancer. 残胃癌全胃切除术后并发症及危险因素分析。
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e19
Sin Hye Park, Sang Soo Eom, Bang Wool Eom, Hong Man Yoon, Young-Woo Kim, Keun Won Ryu
{"title":"Postoperative Complications and Their Risk Factors of Completion Total Gastrectomy for Remnant Gastric Cancer Following an Initial Gastrectomy for Cancer.","authors":"Sin Hye Park,&nbsp;Sang Soo Eom,&nbsp;Bang Wool Eom,&nbsp;Hong Man Yoon,&nbsp;Young-Woo Kim,&nbsp;Keun Won Ryu","doi":"10.5230/jgc.2022.22.e19","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e19","url":null,"abstract":"<p><strong>Purpose: </strong>Completion total gastrectomy (CTG) for remnant gastric cancer (RGC) is a technically demanding procedure and associated with increased morbidity. The present study aimed to evaluate postoperative complications and their risk factors following surgery for RGC after initial partial gastrectomy due to gastric cancer excluding peptic ulcer.</p><p><strong>Materials and methods: </strong>We retrospectively reviewed the data of 107 patients who had previously undergone an initial gastric cancer surgery and subsequently underwent CTG for RGC between March 2002 and December 2020. The postoperative complications were graded using the Clavien-Dindo classification. Logistic regression analyses were used to determine the risk factors for complications.</p><p><strong>Results: </strong>Postoperative complications occurred in 34.6% (37/107) of the patients. Intra-abdominal abscess was the most common complication. The significant risk factors for overall complications were multi-visceral resections, longer operation time, and high estimated blood loss in the univariate analysis. The independent risk factors were multi-visceral resection (odds ratio [OR], 2.832; 95% confidence interval [CI], 1.094-7.333; P=0.032) and longer operation time (OR, 1.005; 95% CI, 1.001-1.011; P=0.036) in the multivariate analysis. Previous reconstruction type, minimally invasive approach, and current stage were not associated with the overall complications.</p><p><strong>Conclusions: </strong>Multi-visceral resection and long operation time were significant risk factors for the occurrence of complications following CTG rather than the RGC stage or surgical approach. When multi-visceral resection is required, a more meticulous surgical procedure is warranted to improve the postoperative complications during CTG for RGC after an initial gastric cancer surgery.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/42/jgc-22-210.PMC9359885.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Potential Applicability of Local Resection With Prophylactic Left Gastric Artery Basin Dissection for Early-Stage Gastric Cancer in the Upper Third of the Stomach. 胃上1/3部位早期胃癌局部切除加预防性胃左动脉盆腔离断术的潜在适用性
IF 3.2 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e17
Yoshimasa Akashi, Koichi Ogawa, Katsuji Hisakura, Tsuyoshi Enomoto, Yusuke Ohara, Yohei Owada, Shinji Hashimoto, Kazuhiro Takahashi, Osamu Shimomura, Manami Doi, Yoshihiro Miyazaki, Kinji Furuya, Shoko Moue, Tatsuya Oda
{"title":"Potential Applicability of Local Resection With Prophylactic Left Gastric Artery Basin Dissection for Early-Stage Gastric Cancer in the Upper Third of the Stomach.","authors":"Yoshimasa Akashi, Koichi Ogawa, Katsuji Hisakura, Tsuyoshi Enomoto, Yusuke Ohara, Yohei Owada, Shinji Hashimoto, Kazuhiro Takahashi, Osamu Shimomura, Manami Doi, Yoshihiro Miyazaki, Kinji Furuya, Shoko Moue, Tatsuya Oda","doi":"10.5230/jgc.2022.22.e17","DOIUrl":"10.5230/jgc.2022.22.e17","url":null,"abstract":"<p><strong>Purpose: </strong>Total or proximal gastrectomy of the upper-third early gastric cancer (u-EGC) often causes severe post-gastrectomy syndrome, suggesting that these procedures are extremely invasive for patients without pathologically positive lymph node (LN) metastasis. This study aimed to evaluate the clinical applicability of a stomach function-preserving surgery, local resection (LR), with prophylactic left gastric artery (LGA)-basin dissection (LGA-BD).</p><p><strong>Materials and methods: </strong>The data of patients with u-EGC (pathologically diagnosed as T1) were retrospectively analyzed. Total gastrectomy was performed in 30 patients, proximal gastrectomy in 45, and subtotal gastrectomy in 6; the LN status was evaluated assuming that the patients had already underwent LR + LGA-BD. This procedure was considered feasible in patients without LN metastases or in patients with cancer in the LGA basin. The reproducibility of the results was also evaluated using an external validation dataset.</p><p><strong>Results: </strong>Of the 82 eligible patients, 79 (96.3%) were cured after undergoing LR + LGA-BD, 74 (90.2%) were pathologically negative for LN metastases, and 5 (6.1%) had LN metastases, but these findings were only observed in the LGA basin. Similarly, of the 406 eligible tumors in the validation dataset, 396 (97.5%) were potentially curative. Tumors in the lesser curvature, post-endoscopic resection status, and small tumors (<20 mm) were considered to be stronger indicators of LR + LGA-BD as all subpopulation cases met our feasibility criteria.</p><p><strong>Conclusions: </strong>More than 95% of the patients with u-EGC might be eligible for LR + LGA-BD. This function-preserving procedure may contribute to the development of u-EGC without pathological LN metastases, especially for tumors located at the lesser curvature.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/38/jgc-22-184.PMC9359880.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40591588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Convenience of Adding a Needle Grasper in Single-Incision Laparoscopic Distal Gastrectomy With Billroth I Anastomosis for Clinical Early Gastric Cancer. 临床早期胃癌单切口腹腔镜远端胃切除术Billroth I型吻合术加抓针器的便利性。
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e24
Jong Won Kim, Joong-Min Park, Kyong-Choun Chi
{"title":"Convenience of Adding a Needle Grasper in Single-Incision Laparoscopic Distal Gastrectomy With Billroth I Anastomosis for Clinical Early Gastric Cancer.","authors":"Jong Won Kim,&nbsp;Joong-Min Park,&nbsp;Kyong-Choun Chi","doi":"10.5230/jgc.2022.22.e24","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e24","url":null,"abstract":"<p><strong>Purpose: </strong>To overcome the technical difficulties of single-incision laparoscopic distal gastrectomy (SILDG), needle grasper (Endo Relief<sup>TM</sup>)-assisted SILDG (NASILDG) was developed. Here, we compared the operative convenience and postoperative outcomes between SILDG and NASILDG.</p><p><strong>Materials and methods: </strong>A needle grasper was inserted into the right upper abdomen and used in the NASILDG. We retrospectively reviewed patients who underwent D1 + dissection and delta-shaped Billroth I anastomosis with SILDG or NASILDG performed by a single surgeon between September 2015 and August 2018.</p><p><strong>Results: </strong>The SILDG (male, 50.0%) and NASILDG (male, 60.0%) groups included 10 and 15 patients, respectively. The operative time without combined operation and anastomosis was significantly shorter in the NASILDG group. Early complications and scar characteristics were not significantly different between the two groups.</p><p><strong>Conclusions: </strong>By adding a needle grasper, SILDG became more convenient without decreasing cosmetic results. NASILDG could be a recommended method to reduce the technical difficulty of SILDG.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/15/51/jgc-22-248.PMC9359886.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy. 肿瘤位置对全胃或近端胃切除术患者生活质量的影响。
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e23
Muneharu Fujisaki, Takashi Nomura, Hiroharu Yamashita, Yoshikazu Uenosono, Tetsu Fukunaga, Eigo Otsuji, Masahiro Takahashi, Hideo Matsumoto, Atsushi Oshio, Koji Nakada
{"title":"Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy.","authors":"Muneharu Fujisaki,&nbsp;Takashi Nomura,&nbsp;Hiroharu Yamashita,&nbsp;Yoshikazu Uenosono,&nbsp;Tetsu Fukunaga,&nbsp;Eigo Otsuji,&nbsp;Masahiro Takahashi,&nbsp;Hideo Matsumoto,&nbsp;Atsushi Oshio,&nbsp;Koji Nakada","doi":"10.5230/jgc.2022.22.e23","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e23","url":null,"abstract":"<p><strong>Purpose: </strong>Most studies have investigated the differences in postgastrectomy quality of life (QOL) based on the surgical procedure or reconstruction method adopted; only a few studies have compared QOL based on tumor location. This large-scale study aims to investigate the differences in QOL between patients with esophagogastric junction cancer (EGJC) and those with upper third gastric cancer (UGC) undergoing the same gastrectomy procedure to evaluate the impact of tumor location on postoperative QOL.</p><p><strong>Methods: </strong>The Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45) questionnaire was distributed in 70 institutions to 2,364 patients who underwent gastrectomy for EGJC or UGC. A total of 1,909 patients were eligible for the study, and 1,744 patients who underwent total gastrectomy (TG) or proximal gastrectomy (PG) were selected for the final analysis. These patients were divided into EGJC and UGC groups; thereafter, the PGSAS-45 main outcome measures (MOMs) were compared between the two groups for each type of gastrectomy.</p><p><strong>Results: </strong>Among the post-TG patients, only one MOM was significantly better in the UGC group than in the EGJC group. Conversely, among the post-PG patients, postoperative QOL was significantly better in 6 out of 19 MOMs in the UGC group than in the EGJC group.</p><p><strong>Conclusions: </strong>Tumor location had a minimal effect on the postoperative QOL of post-TG patients, whereas among post-PG patients, there were definite differences in postoperative QOL between the two groups. It seems reasonable to conservatively estimate the benefits of PG in patients with EGJC compared to those in patients with UGC.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/23/jgc-22-235.PMC9359888.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Epidemiology of Gastric Cancer in Korea: Trends in Incidence and Survival Based on Korea Central Cancer Registry Data (1999-2019). 韩国胃癌流行病学:基于韩国中央癌症登记数据(1999-2019)的发病率和生存趋势
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e21
Sin Hye Park, Mee Joo Kang, E Hwa Yun, Kyu-Won Jung
{"title":"Epidemiology of Gastric Cancer in Korea: Trends in Incidence and Survival Based on Korea Central Cancer Registry Data (1999-2019).","authors":"Sin Hye Park,&nbsp;Mee Joo Kang,&nbsp;E Hwa Yun,&nbsp;Kyu-Won Jung","doi":"10.5230/jgc.2022.22.e21","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e21","url":null,"abstract":"<p><p>This study investigated the trends of gastric cancer in Korea by adding the latest updated gastric cancer data from 2019. Gastric cancer incidence between 1999 and 2019 was reviewed using data from the Korea Central Cancer Registry. The study period was divided into 3 periods: period I (1999-2005), period II (2006-2012), and period III (2013-2019). The incidence, mortality, tumor location, histology, stage, and treatment were analyzed. Between 1999 and 2019, 577,502 patients were newly diagnosed with gastric cancer in Korea, accounting for 33.2% of patients aged ≥70 years. The age-standardized incidence rate (per 100,000) significantly decreased from 2011 (43.0) to 2019 (29.6), with an annual percent change of -4.50. Additionally, the age-standardized mortality rate (per 100,000) markedly decreased from 1999 (23.9) to 2019 (6.7). The proportions of patients with cardia and fundus cancers remained consistent. The proportion of localized stage cases increased, while those of regional and distant stages decreased. The rate of surgical treatment increased in localized and regional stages from 2006 to 2019. The overall 5-year relative survival (5YRS) rate of gastric cancer (per 100,000) increased from 55.7% in period I to 77.0% in period III. From 2013 to 2019, the 5YRS rates of patients (per 100,000) who underwent surgical treatment were 100.6% and 70.5% in the localized and regional stages, respectively. The results of this study demonstrated several changes in the epidemiology of gastric cancer in Korea. This study provides information to help understand the current trends in gastric cancer in Korea.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d3/7e/jgc-22-160.PMC9359882.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40591586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
Clinical Comparison of Proximal Gastrectomy With Double-Tract Reconstruction Versus Total Gastrectomy With Roux-en-Y Anastomosis for Siewert Type II/III Adenocarcinoma of the Esophagogastric Junction. 食管胃交界siwert II/III型腺癌近端胃切除术双道重建与全胃切除术Roux-en-Y吻合术的临床比较
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e25
Xiaoming Ma, Mingzuo Zhao, Jian Wang, Haixing Pan, Jianqiang Wu, Chungen Xing
{"title":"Clinical Comparison of Proximal Gastrectomy With Double-Tract Reconstruction Versus Total Gastrectomy With Roux-en-Y Anastomosis for Siewert Type II/III Adenocarcinoma of the Esophagogastric Junction.","authors":"Xiaoming Ma,&nbsp;Mingzuo Zhao,&nbsp;Jian Wang,&nbsp;Haixing Pan,&nbsp;Jianqiang Wu,&nbsp;Chungen Xing","doi":"10.5230/jgc.2022.22.e25","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e25","url":null,"abstract":"<p><strong>Purpose: </strong>The incidence of adenocarcinoma of the esophagogastric junction (AEG) has increased in recent years, and the optimal surgical strategy for AEG remains highly controversial. We aimed to evaluate the safety and efficacy of proximal gastrectomy with double-tract reconstruction (PG-DT) for the treatment of patients with AEG.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed patients with Siewert type II/III AEG between January 2013 and July 2018. Clinicopathological characteristics, survival, surgical outcomes, quality of life (QOL), and nutritional status were compared between the PG-DT and total gastrectomy with Roux-en-Y anastomosis (TG-RY) groups.</p><p><strong>Results: </strong>After propensity score matching, 33 patients in each group were analyzed. There were no statistical differences between the 2 groups in terms of disease-free survival and overall survival. The surgical option was not an independent prognostic factor based on the multivariate analysis. In addition, no differences were found in terms of surgical complications. There were no significant differences in QOL assessed by the Visick grade, Gastrointestinal Symptom Rating Scale, or endoscopic findings. Furthermore, the long-term nutritional advantage of the PG-DT group was significantly greater than that of the TG-RY group.</p><p><strong>Conclusions: </strong>PG-DT is a safe and effective procedure for patients with local Siewert type II/III AEG, regardless of the TNM stage.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ba/5e/jgc-22-220.PMC9359881.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Evidence for a Paradigm Shift in Gastric Cancer Prevention From Endoscopic Screening to Helicobacter pylori Eradication in Korea. 目前的证据表明,在韩国,胃癌预防从内镜筛查到根除幽门螺杆菌的范式转变。
IF 2.5 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e22
Young-Il Kim, Il Ju Choi
{"title":"Current Evidence for a Paradigm Shift in Gastric Cancer Prevention From Endoscopic Screening to <i>Helicobacter pylori</i> Eradication in Korea.","authors":"Young-Il Kim,&nbsp;Il Ju Choi","doi":"10.5230/jgc.2022.22.e22","DOIUrl":"https://doi.org/10.5230/jgc.2022.22.e22","url":null,"abstract":"<p><p>Gastric cancer is prevalent in Korea and ranked as the third most common cancer in 2019, followed by lung and thyroid cancers. The National Cancer Screening Program (NCSP) for gastric cancer has been implemented in adults aged ≥40 since 1999 and involves endoscopic screening every 2 years. The beneficial effects of the current NCSP on early cancer detection, cost-effectiveness, and mortality reduction are evident. However, the screening program results in a large socioeconomic burden and the consumption of medical resources, as it focuses solely on secondary prevention (early detection) rather than primary prevention of cancer. <i>Helicobacter pylori</i> is defined as a group I carcinogen by the International Agency for Research on Cancer. Hence, its eradication has been suggested as an important primary gastric cancer prevention strategy. Well-designed randomized controlled trials involving high-risk groups (post-endoscopic resection of early gastric cancer and family history of gastric cancer) and long-term follow-up studies in the general population have provided high-quality evidence regarding the effects of <i>H. pylori</i> eradication on gastric cancer prevention. In this review, we discussed the evidences for a possible modification of the current gastric cancer secondary prevention strategy by introducing primary prevention through <i>H. pylori</i> eradication. Areas for future research to optimize primary prevention strategies were also suggested.</p>","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/48/jgc-22-169.PMC9359887.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40591587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Surgical Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Does the Age Matter? 胃癌胃切除术患者的手术效果:年龄是否重要?
IF 3.2 4区 医学
Journal of Gastric Cancer Pub Date : 2022-07-01 DOI: 10.5230/jgc.2022.22.e20
Bang Wool Eom
{"title":"Surgical Outcomes of Patients Undergoing Gastrectomy for Gastric Cancer: Does the Age Matter?","authors":"Bang Wool Eom","doi":"10.5230/jgc.2022.22.e20","DOIUrl":"10.5230/jgc.2022.22.e20","url":null,"abstract":"","PeriodicalId":56072,"journal":{"name":"Journal of Gastric Cancer","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9e/6f/jgc-22-157.PMC9359883.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40591126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信