Gynecologie Obstetrique Fertilite & Senologie最新文献

{"title":"Extension de l’Utilisation de Gamètes en IntraConjugal (EUGIC) : quel usage des spermatozoïdes d’une femme trans ?","authors":"Marie Mesnil ,&nbsp;Laurence Brunet ,&nbsp;Noémie Ranisavljevic ,&nbsp;Sophie Brouillet ,&nbsp;Bérengère Ducrocq ,&nbsp;Arnaud Reigner ,&nbsp;Chadi Yazbeck ,&nbsp;Valerica-Gabriela Oancea ,&nbsp;Catherine Metzler-Guillemain ,&nbsp;Jeanine Ohl ,&nbsp;Hélène Letur ,&nbsp;Florence Eustache ,&nbsp;Célia Ravel","doi":"10.1016/j.gofs.2024.08.002","DOIUrl":"10.1016/j.gofs.2024.08.002","url":null,"abstract":"<div><h3>Objective</h3><div>The French Law relating to Bioethics allows access to medically assisted reproduction for lesbian couples and single women and has expanded the possibilities for self-preservation of gametes. The question now arises of new uses of gametes of the couple, within couples of two cis women, one cis woman and one transgender woman, or two transgender individuals. The acronym EUGIC (Extension of the Use of Gametes in IntraCouple) allows these new situations to be grouped together, particularly if gametes have already been previously cryopreserved, thus avoiding the need for gamete donation.</div></div><div><h3>Methods</h3><div>Analysis of the different situations of sperm use from a trans woman using gametes available within the couple rather than gamete donation.</div></div><div><h3>Results</h3><div>The inconsistency in the use of sperm from a trans woman, the situations already encountered by professionals, the prospects for filiation for a trans woman as well as the issues related to the interest of the unborn child are discussed.</div></div><div><h3>Conclusion</h3><div>French law does not fully address the use of a trans woman's spermatozoa to meet the new EUGIC requirements and leads to complex situations for healthcare professionals.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 20-24"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surveillance fœtale : limites actuelles et nouvelles pistes basées sur l’analyse du système nerveux autonome fœtal","authors":"Charles Garabedian ,&nbsp;Louise Ghesquière ,&nbsp;Véronique Debarge ,&nbsp;Dyuti Sharma ,&nbsp;Laurent Storme ,&nbsp;Kevin Le Duc ,&nbsp;Pierre Charlier ,&nbsp;Anne Wojtanowski ,&nbsp;Laure Lacan ,&nbsp;Julien De Jonckheere","doi":"10.1016/j.gofs.2024.09.001","DOIUrl":"10.1016/j.gofs.2024.09.001","url":null,"abstract":"<div><h3>Objective</h3><div>Currently, fetal monitoring during labor is based on visual analysis of the fetal heart rate (FHR). This test is imperfect, with high intra- and inter-observer variability and a moderate to poor prediction of the occurrence of neonatal acidosis or anoxic-ischaemic encephalopathy. In situations where there is an intermediate risk of acidosis, it is possible to use second-line tests such as blood scalp sampling (with pH or lactate measurement) or ST segment analysis of the fetal ECG. However, these invasive tests have many limitations and their place is debated. Some authors suggest a more physiological approach to FHR assessment. The main actor in maintaining fetal homeostasis is the autonomic nervous system (ANS). Its activity can be assessed by analysing heart rate variability (HRV). The aim is to assess whether HRV can be used to identify situations at risk of acidosis.</div></div><div><h3>Materials and methods</h3><div>Our team has developed an index, the Fetal Stress Index, to measure HRV. To test it in a situation of acidosis, we used a pregnant ewe model. We also developed in parallel a human fetal ECG recording system.</div></div><div><h3>Results</h3><div>In our experimental model, we have shown that this index reflects variations in the parasympathetic system and correlates with the onset of acidosis. As its use in clinical practice requires the acquisition of a beat-to-beat FHR signal, we have also developed an abdominal patch that allows highly accurate analysis of the fetal ECG.</div></div><div><h3>Conclusion</h3><div>The future is therefore to validate the FSI as a marker of acidosis in a prospective cohort using the signal obtained from our patch. This could be a new tool for fetal monitoring during labor.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 30-37"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application en routine des résultats d’un essai randomisé : performance de l’échographie en pratique courante pour le dépistage de la macrosomie fœtale","authors":"Charlotte Cabaud ,&nbsp;Juliette François ,&nbsp;Pierre Capitanio ,&nbsp;Claire Thuillier ,&nbsp;Paul Berveiller ,&nbsp;Patrick Rozenberg ,&nbsp;Thibaud Quibel","doi":"10.1016/j.gofs.2024.09.005","DOIUrl":"10.1016/j.gofs.2024.09.005","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the performance of ultrasound at 36 weeks of gestation for screening fetal macrosomia according to the criteria of the randomized “DAME” trial.</div></div><div><h3>Method</h3><div>Retrospective observational study over 2 years in a type 3 maternity hospital. The primary outcome was birth weight above the 97th percentile on Audipog birth weight curves. The sensitivity, specificity, positive and negative predictive value of ultrasound at 36 SA for predicting macrosomia were calculated. For each patient, the absolute value of the difference between actual and estimated weight [EPF difference<!--> <!-->=<!--> <!-->(Birth weight − Estimated weight)/Birth weight] was calculated. Among undetected macrosomic newborns (≥<!--> <!-->97th Audipog percentile), risk factors associated with misdiagnosis were investigated (false negatives versus true positives).</div></div><div><h3>Results</h3><div>Ultrasound estimation of fetal weight at 36 SA to detect fetal macrosomia had a sensitivity of 43.7% and a specificity of 82.1%. With a positive predictive value for ultrasound of 36,9% and a negative predictive value of 85.8%. The mean absolute value of the difference between estimated and actual birth weight was 287<!--> <!-->g (95% CI [115–409]), with a mean relative difference of 6.8% (95% CI [3.0–11.3]). A relative difference of less than 10% between the estimated weight and the birth weight was found in 68.5% of the patients. Among macrosomic newborns (≥<!--> <!-->97th percentile), a third-trimester estimated fetal weight at or above the 90th percentile, along with a history of fetal macrosomia in a previous pregnancy, reduced the risk of false negatives in the screening ultrasound at 36 weeks of gestation.</div></div><div><h3>Conclusion</h3><div>Ultrasound performed at 36 weeks’ gestation in a population targeted for suspected fetal macrosomia in routine practice has moderate sensitivity and positive predictive value. It would be timely for teams also applying this protocol to share their results, in order to verify whether or not our findings can be generalized to a larger scale.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 3-9"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Première naissance française en AMP intraconjugale chez un couple composé d’une femme cisgenre et d’une femme transgenre","authors":"Maeva Razafintsalama ,&nbsp;Arnaud Reignier ,&nbsp;Maxime Chaillot ,&nbsp;Thomas Freour","doi":"10.1016/j.gofs.2024.09.003","DOIUrl":"10.1016/j.gofs.2024.09.003","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 41-42"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sananès N, Vigoureux S, Sibiude J, Garabedian C, Maurice P. Réponse à l’article de Boujenah J, Moise KJ, d’Ercole C, Carbonne B., intitulé « Recommandation sur la prévention de l’allo-immunisation au 1er trimestre : La désescalade est-elle vraiment raisonnable ? » Gynecol Obstet Fertil 2024; doi:10.1016/j.gofs.2024.09.008","authors":"Nicolas Sananès ,&nbsp;Solène Vigoureux ,&nbsp;Jeanne Sibiude ,&nbsp;Charles Garabedian ,&nbsp;Paul Maurice","doi":"10.1016/j.gofs.2024.10.001","DOIUrl":"10.1016/j.gofs.2024.10.001","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 48-49"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommandations pour la pratique clinique du CNGOF sur la prévention de l’allo-immunisation Rhésus au 1er trimestre : la désescalade est-elle vraiment raisonnable ?","authors":"Jeremy Boujenah ,&nbsp;Kenneth J. Moise ,&nbsp;Claude d’Ercole ,&nbsp;Bruno Carbonne","doi":"10.1016/j.gofs.2024.09.008","DOIUrl":"10.1016/j.gofs.2024.09.008","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 45-47"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Améliorer la santé gynécologique : 10 changements pour vivre mieux avec son environnement","authors":"Louise Benoit ,&nbsp;Pascale Delille ,&nbsp;Sylvie Alemanno ,&nbsp;Anne-Sophie Bats ,&nbsp;Meriem Koual","doi":"10.1016/j.gofs.2024.10.005","DOIUrl":"10.1016/j.gofs.2024.10.005","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 42-44"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Que pensent les professionnels français des limites actuelles de l’AMP en France, la loi de bioéthique doit-elle évoluer ?","authors":"Joelle Belaisch Allart","doi":"10.1016/j.gofs.2024.11.001","DOIUrl":"10.1016/j.gofs.2024.11.001","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 1-2"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sommaire","authors":"","doi":"10.1016/S2468-7189(24)00362-3","DOIUrl":"10.1016/S2468-7189(24)00362-3","url":null,"abstract":"","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages iii-iv"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143097270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paragangliome et grossesse : une histoire mictionnelle palpitante","authors":"Geoffrey Groussard ,&nbsp;Alexandre Esnault ,&nbsp;Quentin Meurdra ,&nbsp;Michael Joubert ,&nbsp;Thérèse Simonet ,&nbsp;Adrien Lee Bion ,&nbsp;Michel Dreyfus","doi":"10.1016/j.gofs.2024.10.008","DOIUrl":"10.1016/j.gofs.2024.10.008","url":null,"abstract":"<div><h3>Objectives</h3><div>Carrying out a pregnancy to term in a patient with a paraganglioma or pheochromocytoma (PPGL) results from a multidisciplinary challenge. The objective was to compare our therapeutic attitude with the existing literature and to identify optimal treatment.</div></div><div><h3>Methods</h3><div>Description of a case of paraganglioma treated during pregnancy at the University Hospital Center of Caen (France) in 2024 and comparison with the literature.</div></div><div><h3>Results</h3><div>We describe a patient with a family history of paraganglioma, in whom paravesical PPGL was discovered at 18 weeks of gestation. The symptoms were marked by episodes of palpitations and headaches during urination. The diagnosis was confirmed by a measurement of urinary metanephrines associated with magnetic resonance imaging. After initiation of alpha-blocker treatment, delivery was performed by cesarean section at 36 weeks of gestation. An excision was carried out by laparoscopy 2 months postpartum without intra- and postoperative complications.</div></div><div><h3>Conclusions</h3><div>The absence of antenatal diagnosis of PPGL is the main risk factor increasing maternal and fetal mortality. Certain criteria such as a family history, the appearance of early or malignant arterial hypertension should suggest the diagnosis of PPGL. The initiation of alpha-blocker treatment upon diagnosis is essential. The curative therapy remains surgical excision. Its timing depends on its size, location, term of pregnancy and route of delivery. It is preferable to postpone it until postpartum in order to reduce the risk of complications.</div></div>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":"53 1","pages":"Pages 10-15"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}