Journal of Stomatology Oral and Maxillofacial Surgery最新文献_第8页

Immediate oral feeding after free-flap reconstruction of the oral cavity. 自由皮瓣重建口腔后立即口服喂养。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-10 DOI: 10.1016/j.jormas.2024.102196

Hugo Poncet, Franck Delanoë, Frédéric Lauwers, Chris Passalboni, Pierre Molla-de-Testa, Alice Prevost

{"title":"Immediate oral feeding after free-flap reconstruction of the oral cavity.","authors":"Hugo Poncet, Franck Delanoë, Frédéric Lauwers, Chris Passalboni, Pierre Molla-de-Testa, Alice Prevost","doi":"10.1016/j.jormas.2024.102196","DOIUrl":"10.1016/j.jormas.2024.102196","url":null,"abstract":"Aim: There remains no consensus on the definition or value of early oral feeding after head and neck surgery. The main objective of this study was to determine how immediate oral feeding (IOF) with soft diet within 2 days following free-flap reconstruction of the oral cavity affected severe post-operative morbidity within 30 days and length of hospital stay (LoS).Methods: A retrospective cohort study was carried out in 2021-2023 in our tertiary hospital center. The associations between severe post-operative morbidity and LoS with the independent variable of IOF were analyzed by multivariate regression analysis. We also examined the factors associated with delayed oral feeding (DOF); lack of oral feeding within 10 post-operative days. The confounding variables adjusted for were demographic-related (age, sex), comorbidity-related (ASA score, undernutrition, prior history), and surgery-related (substance loss type/location, flap type).Results: Inclusion was 132 patients: n = 29/132 (22 %) IOF patients versus n = 103/132 (78 %) patients undergoing oral feeding after ≥3 post-operative days. IOF was found independently associated with reduced severe post-operative morbidity within 30 days (AOR 0.3[0.1-0.8], p = 0.01) and shorter length of stay (AEE -6.7 [-11.8--1.6], p = 0.01) compared to oral feeding after ≥3 post-operative days. DOF was found positively associated with cardiovascular history (AOR 2.7[1.1-7.3], p = 0.04) but negatively associated with a history of head and neck surgery with radiotherapy (AOR 0.4[0.1-0.8], p = 0.05).Conclusion: Protocols for post-operative oral feeding should consider IOF. Criteria for good candidates for IOF require further definition for surgeons to implement IOF more widely.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102196"},"PeriodicalIF":2.2,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the role of Osteopontin in prognosis of oral squamous cell carcinoma- A systematic review. 评估骨桥蛋白在口腔鳞状细胞癌预后中的作用——一项系统综述。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-07 DOI: 10.1016/j.jormas.2024.102184

Parasakthi Madhavan, Kavitha Sanjeev

{"title":"Assessing the role of Osteopontin in prognosis of oral squamous cell carcinoma- A systematic review.","authors":"Parasakthi Madhavan, Kavitha Sanjeev","doi":"10.1016/j.jormas.2024.102184","DOIUrl":"10.1016/j.jormas.2024.102184","url":null,"abstract":"Background: Oral cancer is always a global burden. It is the sixteenth most common cancer. It leads to metastasis since it is often diagnosed at late stages. To monitor the progress of this condition, various biomarkers are being utilized. Osteopontin is one such biomarker and its level in bodily fluids can be used as a reliable biomarker.Aims and objectives: The current study aims to review and evaluate the prognostic role of osteopontin in oral squamous cell carcinoma.Materials and methods: A literature search was conducted across various databases such as Scopus, PubMed and Google Scholar. It yielded 18 articles totally using MeSH terms. The inclusion criteria were original research articles written only in English language involving both tissue and plasma osteopontin on oral cancer patients. Of these, only two articles which met the inclusion criteria were added into this systematic review. The search had no time restriction.Results: The studies showed that osteopontin play a vital role in the prognosis of the OSCC patients. One study from Taiwan and other from India proved the osteopontin expression in plasma and tissue can help to predict the prognosis of patients with oral cancer. Also, the level of plasma osteopontin was correlated with aggressiveness of OSCC. Tissue osteopontin expression was significantly lower in stage I OSCC patients when compared with stage II and III. Since there were only two studies, there is limited evidence of results.Conclusion: From these findings, osteopontin can also be used as a reliable biomarker to predict the prognosis of oral cancer. Since there were only two studies to substantiate the finding, there is limited evidence and more studies are warranted to confirm the results.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102184"},"PeriodicalIF":2.2,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tetrafid and trifid mandibular condyle: A case report. 四裂、三裂下颌髁1例。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-05 DOI: 10.1016/j.jormas.2024.102191

Ayşegül Türkmenoğlu, Bengisu Yıldırım

引用次数: 0

Analysis of recurrence factors after radical mandibular resection for ameloblastoma. 下颌骨成釉细胞瘤根治术后复发因素分析。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-05 DOI: 10.1016/j.jormas.2024.102190

Lei Chen, Xu-Hui Zhang, Ping Zhou, Yi-Fang Zhao, Yan-Ping Hu, Jun Jia, Zi-Li Yu

{"title":"Analysis of recurrence factors after radical mandibular resection for ameloblastoma.","authors":"Lei Chen, Xu-Hui Zhang, Ping Zhou, Yi-Fang Zhao, Yan-Ping Hu, Jun Jia, Zi-Li Yu","doi":"10.1016/j.jormas.2024.102190","DOIUrl":"10.1016/j.jormas.2024.102190","url":null,"abstract":"Background: To analyze causes of recurrence following radical mandibular resection of ameloblastoma, and to propose surgical variation.Methods: We conducted a retrospective analysis of patients treated for ameloblastoma from 2012 to 2024, specifically those who underwent radical mandibular resection followed by reconstruction with autologous bone flaps, focusing on cases of recurrence.Results: Six patients were included in the study, all with primary tumors located in the mandible. Recurrence occurred 5 to 23 years post-surgery. Two patients had recurrence within the residual mandible due to insufficient margins, necessitating further resection and reconstructed with bone flaps Three patients had recurrences associated with residual tumor cells in the soft tissue, which affected the grafted bone: two required extensive resection and additional bone flap reconstruction, while one had a limited recurrence that was managed by soft tissue excision. Additionally, one patient had an isolated soft tissue recurrence that was addressed through resection.Conclusion: Adequate resection margins are vital to minimizing recurrence risk. Invasive procedures should be avoided to prevent tumor spread, and thorough excision of affected areas during surgery is essential.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102190"},"PeriodicalIF":2.2,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Full endoscopic submandibular gland excision through the retroauricular hairline approach: A cohort study. 经耳后发际入路的全内窥镜颌下腺切除术：一项队列研究。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-04 DOI: 10.1016/j.jormas.2024.102186

Jialu He, Lan Xiao, Grace Paka Lubamba, Chang Cao, Su Chen, Fan Yang, Heyi Tang, Guiquan Zhu

{"title":"Full endoscopic submandibular gland excision through the retroauricular hairline approach: A cohort study.","authors":"Jialu He, Lan Xiao, Grace Paka Lubamba, Chang Cao, Su Chen, Fan Yang, Heyi Tang, Guiquan Zhu","doi":"10.1016/j.jormas.2024.102186","DOIUrl":"https://doi.org/10.1016/j.jormas.2024.102186","url":null,"abstract":"Introduction: Submandibular gland (SMG) excision can be achieved by conventional approach (Conv) through a cervical incision or endoscopic surgery (Endo). The aim of this study was to propose a new concept and technique of full endoscopic SMG excision through the retroauricular hairline incision and investigate its safety and feasibility.Materials and methods: A total of 141 patients with SMG diseases treated at our department from 2021 to 2024 were retrospectively enrolled in the Endo group (n = 74) and the Conv group (n = 67). Interested variables included age, sex, pathological diagnosis, incision length, intraoperative bleeding, operation duration, hospitalization stay, complications, and aesthetic satisfaction score. SPSS software 26.0 and G power 3.1.9 were used for analysis.Results: There were no significant differences between the two groups in age, sex, follow-up period, pathological type, incision length or postoperative complications. Significant differences were found for the amount of bleeding [Endo: 12.5 (10.0) mL; Conv: 20.0 (20.0) mL, P < 0.001] and aesthetic satisfaction score [Endo: 8.8 ± 1.3; Conv: 7.5 ± 1.8, P < 0.001]. The operation duration of the Endo group was longer for early cases [Endo: 110.0 (27.5) min; Conv: 87.0 (40.0) min, P < 0.001], yet there was no significant difference from the thirtieth case [Endo: 85.0 (20.0) min; Conv: 89.0 (52.5) min, P = 0.894]. No recurrence of SMG diseases occurred during the follow-up period.Discussion: Full endoscopic SMG excision through the retroauricular hairline approach results in less intraoperative bleeding, invisible scars, and greater patient satisfaction, achieving ideal clinical and cosmetic outcomes.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102186"},"PeriodicalIF":2.2,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for flap dehiscence and/or necrosis following standard rotational flap in cranial vault osteomyelitis without intracranial involvement: A retrospective study. 无颅内累及的颅拱顶骨髓炎标准旋转皮瓣后皮瓣开裂和/或坏死的危险因素：一项回顾性研究。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-04 DOI: 10.1016/j.jormas.2024.102187

Benjamin Frech, Chidpong Siritongtaworn, Chayawee Muangchan, Chatpong Tangmanee, Keskanya Subbalekha, Nattapong Sirintawat, Jean-Paul Meningaud, Poramate Pitak-Arnnop, Christian Stoll

{"title":"Risk factors for flap dehiscence and/or necrosis following standard rotational flap in cranial vault osteomyelitis without intracranial involvement: A retrospective study.","authors":"Benjamin Frech, Chidpong Siritongtaworn, Chayawee Muangchan, Chatpong Tangmanee, Keskanya Subbalekha, Nattapong Sirintawat, Jean-Paul Meningaud, Poramate Pitak-Arnnop, Christian Stoll","doi":"10.1016/j.jormas.2024.102187","DOIUrl":"10.1016/j.jormas.2024.102187","url":null,"abstract":"Objectives: The study aimed to estimate the incidence of flap dehiscence and/or necrosis (FD/N) following standard rotational flap (SRF) surgery for cranial vault osteomyelitis without intracranial involvement (CVO) and to identify factors associated with these complications.Methods: A retrospective study was conducted using chart reviews of patients who underwent SRF to cover CVO defects over a 10-year period. Twenty-one predictor variables were analysed, categorised into demographic, health status, anatomic, and surgical factors. The primary outcome was the occurrence of FD/N. Descriptive, bi- and multivariate regression analyses were used to identify variables significantly associated with FD/N (P ≤ 0.05).Results: The study included 154 subjects who underwent SRF (26.6 % female), with a mean age of 75.6 ± 12.8 years (range, 26-94). The incidence of FD/N was 5.2 %. Multivariate analysis revealed that smoking (odds ratio [OR] 1.07; P = 0.04), second surgery (OR 1.18; P < 0.001), compromised scalp vascularity (OR 1.1; P = 0.007), and defects at the central scalp and vertex (OR 1.08; P = 0.02) were statistically significantly associated with an increased risk of FD/N.Conclusions: FD/N is an infrequent complication following SRF for CVO. Significant modifiable risk factors included smoking, multiple flap operations, compromised scalp vascularity, and defects at the central scalp and vertex. Addressing these factors may help reduce the risk of FD/N in this patient population. Future research should investigate outcomes among different flap types for CVO defects.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102187"},"PeriodicalIF":2.2,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of clinical and radiographic outcomes at least 5 years after coronectomy for deeply impacted mandibular third molars. 下颌深度阻生第三磨牙冠切除术后至少5年的临床和影像学结果分析。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-04 DOI: 10.1016/j.jormas.2024.102188

Yusuf Tamer, Seçil Çubuk, Efsun Somay, Zafer Özgür Pektaş

{"title":"Analysis of clinical and radiographic outcomes at least 5 years after coronectomy for deeply impacted mandibular third molars.","authors":"Yusuf Tamer, Seçil Çubuk, Efsun Somay, Zafer Özgür Pektaş","doi":"10.1016/j.jormas.2024.102188","DOIUrl":"10.1016/j.jormas.2024.102188","url":null,"abstract":"Objective: Coronectomy is an alternative to traditional mandibular third molar extraction when the inferior alveolar nerve (IAN) is closely associated with the roots of these molars. Given the paucity of research on the long-term outcomes after coronectomy, we conducted this study to evaluate clinical and radiographic outcomes at least 5 years post-coronectomy.Methods: This retrospective study enrolled all patients with impacted mandibular third molars treated with coronectomy at our institution who were willing to return for follow-up evaluation 5 years or more after their original procedure. Patient data were obtained retrospectively from hospital records and during oral examinations at the follow-up study appointment. We assessed the following postoperative clinical outcomes: injury to the IAN, root migration distance, root exposure in the oral cavity, non-healing sockets, pain or sensitivity in the coronectomy area, and the presence of periapical pathology.Results: Of the 196 patients invited to participate, 66 patients (male, 32 %; female, 68 %) who underwent a total of 75 coronectomies were included in this study. No persistent hypoesthesia of the lower lip were reported during follow-up. Two patients required reoperation because of root eruption into the oral cavity. Approximately two-thirds of residual roots migrated from their position on preoperative radiographs; the mean migration distance was 3.2 ± 1.3 mm. Two patients (2.6 %) had pain in the soft tissues around the coronectomy site.Conclusion: Our findings confirm that coronectomy is an effective treatment option for preventing IAN injury when the nerve is in close proximity to the roots of these molars.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102188"},"PeriodicalIF":2.2,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tongue tip reconstruction with sliding tongue flap. 舌瓣滑动重建舌尖。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-04 DOI: 10.1016/j.jormas.2024.102189

Takanori Eguchi, Koji Kawaguchi, Shusuke Yamada, Yoshiki Hamada

引用次数: 0

Effect of COL11A1 on oral squamous cell carcinoma. COL11A1对口腔鳞状细胞癌的影响。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-03 DOI: 10.1016/j.jormas.2024.102183

Yuan-Hang Liu, Dan Li, Hao-Lei Zhang, Bo-Hao Zhang, Wei-Jing Song, Tian-Ke Li

{"title":"Effect of COL11A1 on oral squamous cell carcinoma.","authors":"Yuan-Hang Liu, Dan Li, Hao-Lei Zhang, Bo-Hao Zhang, Wei-Jing Song, Tian-Ke Li","doi":"10.1016/j.jormas.2024.102183","DOIUrl":"10.1016/j.jormas.2024.102183","url":null,"abstract":"Background: Oral squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity, which is mainly a series of atypical hyperplasia of oral epithelial cells, and the overall prognosis remains poor.Methods: GSE37991 and GSE38517 were downloaded from gene expression omnibus (GEO) to identify differentially expressed genes (DEGs). Functional enrichment analysis of DEGs was performed, weighted gene co-expression network analysis (WGCNA) was used. Protein-protein interaction (PPI) network was constructed. Core gene expression was visualized using a heatmap. Comparative toxicogenomics database (CTD) and miRNA analyses identified related diseases and regulatory miRNAs. Western blot (WB) was conducted to examine expression of COL11A1 and TGF-SMAD signaling components in OSCC samples.Results: 5163 DEGs were identified. DEGs were enriched in metabolic processes and signaling pathways, including TGF-β/SMAD and PI3K-Akt. WGCNA identified 11 core modules. PPI network analysis revealed five core genes: COL11A1, AURKA, MELK, CCNA2, and BUB1. Heatmap analysis showed that COL11A1 is highly expressed in OSCC. CTD analysis indicated that COL11A1 is associated with OSCC. miRNA prediction identified potential regulatory factors. Western blot analysis demonstrated that COL11A1 is overexpressed in OSCC and is associated with TGF-SMAD signaling, inflammation, and cell cycle progression.Conclusion: COL11A1 is highly expressed in OSCC and may serve as a target gene interacting with the TGF-SMAD signaling pathway.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102183"},"PeriodicalIF":2.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ossifying fibroma and juvenile ossifying fibroma: A systematic review on clinical and radiological parameters, treatment modalities and recurrence. 骨化性纤维瘤和幼年骨化性纤维瘤：临床和影像学参数、治疗方式和复发的系统综述。

IF 2.2 3区医学

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2024-12-03 DOI: 10.1016/j.jormas.2024.102185

Blandine Gautier, Sophie Dugast, Pierre Guyonvarc'h, Julie Longis, Pierre Corre, Hélios Bertin

{"title":"Ossifying fibroma and juvenile ossifying fibroma: A systematic review on clinical and radiological parameters, treatment modalities and recurrence.","authors":"Blandine Gautier, Sophie Dugast, Pierre Guyonvarc'h, Julie Longis, Pierre Corre, Hélios Bertin","doi":"10.1016/j.jormas.2024.102185","DOIUrl":"10.1016/j.jormas.2024.102185","url":null,"abstract":"Ossifying fibroma (OF) is a rare benign fibro-osseous neoplasm developing mostly in maxillo-facial bones. OF is divided in cemento-ossifying fibroma (COF), juvenile trabecular ossifying fibroma (JTOF) and psammomatoid ossifying fibroma (PSOF). The aim of this systematic review was to synthetize the existing literature on OF, investigating the clinical and radiological parameters related to the different forms of the disease, and to compare the treatment modalities according to their associated recurrence rate. Three databases were searched in March 2024, with an update in September 2024. Eligibility criteria included studies reporting on patients with OF, surgical treatment and follow-up data. Of the 2016 studies identified, 22 were retained after eligibility assessment. A total of 492 patients were included. Most OF presented with painless swelling. COF affected 61.1 % of women with a mean age of 29.5, JTOF presented in 55.7 % of male children, and PSOF had no predilection for sex with a mean age of 19.5 years. Enucleation and curettage were associated with an elevated recurrence rate in JTOF (12/30) and PSOF (10/16). PSOF (6 cases) and JTOF (15 cases) showed no recurrence with radical surgery. Same recurrence rates in COF were seen for conservative and radical surgery. Although radical surgery seemed to avoid recurrence in JTOF and PSOF, conservative surgery such as enucleation and curettage with additional peripheral ostectomy should be considered primarily to lessen the morbidity induced by radical resection. Close clinical and radiological follow-up should be undertaken to diagnose early recurrence.","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102185"},"PeriodicalIF":2.2,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0