{"title":"To study the diagnostic accuracy of diabetes in pregnancy study group of india (DIPSI) as compared with international association of diabetes in pregnancy study group (IADPSG) Criteria in pregnancy","authors":"Vaidehi Chaudhary, P. Dixit","doi":"10.4103/jss.jss_129_22","DOIUrl":"https://doi.org/10.4103/jss.jss_129_22","url":null,"abstract":"Background: Hyperglycemia in pregnancy is associated with adverse maternal and perinatal outcomes. Hence, it is essential to diagnose early and treat to prevent adverse complications. The study aims to ascertain the diagnostic accuracy of the Diabetes in Pregnancy Study Group of India (DIPSI) versus the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria. Methods: Women (n = 200) attending the outpatient or inpatient department of obstetrics and gynecology with gestational age 24–28 weeks were included. As per the DIPSI and IADPSG criteria, all women underwent nonfasting oral glucose tolerance test irrespective of the last meal and after an overnight fast of at least 8 h. A venous blood sample was drawn after glucose administration and was measured by hexokinase technique using an autoanalyzer. Results: Out of 200 women, 47 (23.5%) were diagnosed with gestational diabetes mellitus (GDM) by the IADPSG, whereas 15 (7.5%) were diagnosed with GDM by DIPSI test. Sociodemographic and obstetric characteristics were comparable between the two groups. Women with a history of polycystic ovarian syndrome (odds ratio [OR]: 13.51), family history of DM (OR: 7.02), GDM (OR: 5.8), and perinatal mortality (OR: 4.27) had higher odds of developing GDM. The sensitivity and specificity of DIPSI were 27.66% and 98.69%, respectively, and diagnostic accuracy was 82%. IADPSG test can be recommended as a primary modality of screening GDM in all pregnant women. DIPSI test can be recommended for screening of the patient in non-fasting condition. Hence, by routine IADPSG test and selective DIPSI test, the whole of the antenatal population can be screened without jeopardizing the sensitivity for detection of true cases.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49218641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"”Determining correlation between severity of primary dysmenorrhea and resting metabolic rate in college-going girls of 18–25 years of age:” An observational study","authors":"R. Rathi, Arati V Mahishale","doi":"10.4103/jss.jss_160_22","DOIUrl":"https://doi.org/10.4103/jss.jss_160_22","url":null,"abstract":"Background: Dysmenorrhea is painful cramps originating from the uterus that occurs during menstruation. There is a dearth in the literature assessing a possible association between primary dysmenorrhea and resting metabolic rate (RMR). Aims and Objectives: To find the the correlation resting metabolic rate and primary dysmenorrhea in college going girls between 18 – 25 years using numeric pain rating scale and Harris benedict equation Material and Method: This study included a total of 206 college-going girls between 18 and 25 years of age with primary dysmenorrhea based on the selection criteria. They were administered with the Numerical Pain Rating Scale (NPRS), which divided them into mild, moderate, and severe pain and demographic data including age (years), height (cm), and weight (kg) which was employed into Harris–Benedict Equation to calculate their respective RMR and then it was correlated with the severity of dysmenorrhea. Results: The overall comparison of groups, based on the NPRS values, with RMR scores, showed a statistically significant difference (F = 3.0951, P = 0.0280). While analyzing pair-wise comparison within each group of pain scores for their metabolic rate values, the RMR of females with no pain that is, NPRS score - 0, showed a significantly higher metabolic rate than the ones with mild pain (P = 0.0027), moderate pain (P = 0.0123), as well as the ones with severe pain (P = 0.0036). Spearman rank correlation test revealed no association between different groups of NPRS scores and RMR values (t = −0.0926, P = 0.9263). Conclusion: The study concluded that there is no correlation between the severity of primary dysmenorrhea and RMR in girls between 18 and 25 years. However, girls who do not experience dysmenorrhea showed higher RMR than the girls with primary dysmenorrhea.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43566292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orthograde nonsurgical endodontic therapy of a molar with periapical radiolucency by employing the rotary files and adjunctive laser-assisted disinfection in a claustrophobic pediatric patient: A rare case report with literature review","authors":"Mohammad Khan, M. Jindal","doi":"10.4103/jss.jss_132_22","DOIUrl":"https://doi.org/10.4103/jss.jss_132_22","url":null,"abstract":"Nonsurgical endodontic management of the nonvital posterior tooth with large periapical radiolucency has been suggested as conservative approach in endodontics in existing literature. However, complete disinfection of the infected root canals has been a challenge in endodontic procedure. Recently, various types of lasers have emerged as the effective and successful way for achieving in-depth elimination of bacteria and also for healing of periapical lesions. However, there is a scarcity of published case report articles about laser-assisted endodontic therapy in combination with rotary files system for the noninvasive management of large periapical lesion associated with nonvital posterior teeth in claustrophobic child patients. Hence, the aim of this article is to present the pediatric case report about the successful nonsurgical orthograde endodontic treatment by employing diode laser of 810 nm wavelength for the disinfection of the infected root canals and resolution of periradicular radiolucency followed by functional rehabilitation of the treated tooth with preformed stainless steel crown within the shorter period.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42583513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of Chlamydia trachomatis Infection in a Semi-Urban Setting in Nigeria","authors":"N. Nwachukwu, A. Ulasi, Divine Ezeagwula","doi":"10.4103/jss.jss_151_22","DOIUrl":"https://doi.org/10.4103/jss.jss_151_22","url":null,"abstract":"Background: Chlamydia trachomatis (CT) infection affects over 131 million people annually. It is one of the most prevalent bacterial sexually transmitted infections. This study aimed at the detection of CT infection among young adult females in the Okpoko community, Anambra State, Nigeria. Patients and Methods: Self-collected vaginal swabs from 288 females aged 18–37 years were tested for CT antigen using the Solid Chlamydia Rapid Test kit (USA). Results: CT antigen was detected in 19 (6.6%) samples. The age group of 23–27 years had the highest prevalence rate (10.7%), followed by 18–22 years (8.7%). The married participants were more infected (8.3%) than singles (3.1%) (P < 0.05). A higher percentage of participants (99.3%) were not aware that CT was sexually transmitted. Conclusion: Active CT infection was detected in the Okpoko community. Regular screening of young females as well as propagation of information on sexually transmitted infections should be encouraged to break the community transmission.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43007743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Mishra, S. Vagha, S. Shukla, S. Acharya, M. Jagtap
{"title":"Comparison of Cytokeratin Expression Vis-à-Vis Bloom–Richardson Grading of Breast Carcinoma in Resource-limited Setup: A Cross-sectional Study","authors":"P. Mishra, S. Vagha, S. Shukla, S. Acharya, M. Jagtap","doi":"10.4103/jss.jss_44_22","DOIUrl":"https://doi.org/10.4103/jss.jss_44_22","url":null,"abstract":"Background: Breast cancer is the most common malignant tumor and the leading cause of female mortality. Its incidence and prevalence are rapidly increasing worldwide. Age <35 years, multiple nodal involvements, ad increased size and grade are the bad prognostic factors indicating a higher risk of recurrence. Early diagnosis of breast cancer is one of the best approaches to prevent this disease. Aim: The aim of this study is to develop an understanding of the relationship between cytokeratin (CK) 5/6 and CK 8/18 expression and the Bloom–Richardson (BR) grading of carcinoma breast. Materials and Methods: The present observational, analytical, and cross-sectional study investigated CK 5/6 and CK 8/18 expression in relation to the BR grade in 50 cases of infiltrating ductal carcinoma. Hematoxylin and eosin staining for BR grade and immunohistochemistry for CK 5/6 and CK 8/18 was carried out in the histopathology and immunohistochemistry sections of the Department of Pathology, Jawaharlal Nehru Medical College, Sawangi (M). Results: Out of 50 cases, CK 5/6 expression was observed in the majority of BR Grade III cases (87.50%) indicating a basal phenotype, and CK 8/18 expression was seen in the majority of BR Grade I cases (92.86%) signifying a luminal phenotype. The P value interpretation was found to be statistically significant (<0.05). Conclusions: CKs along with BR grading can be used as an alternative tool for predicting the endocrine status of carcinoma breast instead of employing an expensive panel of markers.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48367015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gender differences in the timing of identification among children with autism","authors":"P. Malhi, P. Singhi","doi":"10.4103/jss.jss_218_22","DOIUrl":"https://doi.org/10.4103/jss.jss_218_22","url":null,"abstract":"Background and Objectives: There is a paucity of research studies, especially from the low- and middle-income countries, on gender-specific clinical profiles of autism and whether this lack of information is a barrier for early diagnosis among females. The present paper examined the gender differences in the timing of identification of autism among children. Methods: The case records diagnosed children with autism spectrum disorder with no documented intellectual disability (IQ <70) were retrospectively analyzed. The demographic and clinical characteristics such as the presence of repetitive behaviors, deficits/delays in language, social-emotional reciprocity impairments, history of developmental regression, presence of hyperactivity, and self-injurious behaviors were extracted from the case files. Gender differences in the timing of identification, clinical characteristics, and sociodemographic variables were examined by utilizing the t-test. Results: A total of 309 case records (Mean = 5.04 years, standard deviation = 2.50) were retrieved. Girls, as compared to boys, were significantly less likely to show restricted and repetitive behaviors (χ2 = 3.92, P = 0.048) and showed greater socio-emotional reciprocity despite a similar level of autism severity (χ2 = 4.48, P = 0.034). No sex differences were found in hyperactivity, self-injurious behavior, history of developmental regression, and severity of autism (all P > 0.05). There was a significant difference in the timing of the identification of autism by gender and females were found to be identified at significantly older ages relative to males (t = 2.13, P = 0.034). Conclusions: There is an imperative need to develop more gender-sensitive diagnostic tools incorporating the sex-specific differences in clinical presentation to improve the assessment of autism in girls.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42883361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Lachyan, V. Singh, Swati Verma, Debashish Paramanick
{"title":"A short review on black fungal mucormycosis accompanied by Post-SARS-CoV-2","authors":"A. Lachyan, V. Singh, Swati Verma, Debashish Paramanick","doi":"10.4103/jss.jss_86_21","DOIUrl":"https://doi.org/10.4103/jss.jss_86_21","url":null,"abstract":"Many people who have recovered from coronavirus disease 2019 (COVID-19) have recently been diagnosed with black fungus – or mucormycosis – disease. Rhino-orbital mucormycosis is becoming more common in people with COVID-19, particularly in India. On its own, diabetes mellitus is a risk factor for severe COVID-19 and mucormycosis. The goal of this study is to conduct a review of the literature to determine the features of patients with mucormycosis and COVID-19. Increased mucormycosis in India appears to be the result of an unholy trifecta of diabetes (high hereditary incidence), corticosteroid overuse (increased blood glucose and opportunistic fungal infection), and COVID-19 (cytokine storm, lymphopenia, and endothelial damage). To limit the incidence of deadly mucormycosis, all efforts should be made to maintain optimum hyperglycemia, and only prudent evidence-based use of corticosteroids in patients with COVID-19 is advocated. In this review, we emphasize knowledge on diagnosis and therapy regarding black fungal mucormycosis, which is accompanied by post-SARS-CoV-2.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48474750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Prasad, J. Sankar, D. Govindan, K. Priyadharsini
{"title":"Efficacy of fentanyl versus clonidine as an adjuvant to ropivacaine compared to ropivacaine for postoperative analgesia in caudal block for infraumblical pediatric surgeries: A prospective double-blinded randomized control study","authors":"T. Prasad, J. Sankar, D. Govindan, K. Priyadharsini","doi":"10.4103/jss.jss_192_22","DOIUrl":"https://doi.org/10.4103/jss.jss_192_22","url":null,"abstract":"Background: Postoperative pain and its management are a budding specialty in the medical field. The additions of adjuvants to local anesthetics were one of the effective methods to improve postoperative analgesia in terms of duration and profile. The study was done primarily to assess the duration of analgesia in terms of pain score and total analgesic requirement among fentanyl and clonidine. Materials and Methods: The study was a double-blinded randomized control trial among 72 pediatric subjects where the subjects were randomly allocated into: Fentanyl group: received 0.75 ml/kg ropivacaine 0.2% along with fentanyl 1 μg/kg, clonidine group received 0.75 ml/kg ropivacaine 0.2% along with clonidine 1 μg/kg and ropivacaine alone group received 0.75 ml/kg 0.2% ropivacaine alone. Pain was assessed by objective pain scale score and Ramsay Sedation Scale was used to assess postoperative sedation. The data were entered into Microsoft Excel and analyzed using SPSS 16. Results: Clonidine group showed bradycardia and hypotension intraoperatively and postoperatively as compared to the other groups (P < 0.05). Both the fentanyl and clonidine group showed increased sedation (3.13 [0.34] vs. 2.13 [0.54] and 1.96 [0.36]) longer duration of analgesia (15.50 [1.35], 11.67 [3.71] and 9.17 [1.86]) and lesser pain score compared to the placebo group (P < 0.05). Among the groups, clonidine showed a better profile. Conclusion: The study concluded that both fentanyl and clonidine as an adjuvant to ropivacaine showed longer duration of analgesia with increased sedation score and lesser pain score. Clonidine showed a better profile in terms of duration of analgesia, pain, and sedation.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44296363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prabhakar Adake, Mahalaxmi S. Petimani, K. Gourav, A. Balakrishna
{"title":"Assessment and Correlation of Adverse Events Following Coronavirus Disease Vaccination with Blood Group and Dietary Style","authors":"Prabhakar Adake, Mahalaxmi S. Petimani, K. Gourav, A. Balakrishna","doi":"10.4103/jss.jss_159_22","DOIUrl":"https://doi.org/10.4103/jss.jss_159_22","url":null,"abstract":"Objectives: The objective of this study is to assess and correlate adverse drug events following coronavirus disease (COVID) vaccination with blood group and dietary style. Methodology: This is a cross-sectional study carried out from May 2021 to July 2021. A prevalidated Google questionnaire containing demographic details, dietary style, blood group, preexisting diseases, and adverse events of the COVID vaccine was circulated to all health-care professionals of our institution through mail/WhatsApp. Informed consent was obtained (in Google Forms) from all the participants after describing the purpose of the study and the assurance to maintain anonymity and confidentiality. A total of 102 responses were collected, out of which 100 (n = 100) responses were analyzed and interpreted (two responses were excluded since participants are not vaccinated). The descriptive statistical method is applied for the assessment of adverse events. The Chi-square test is applied to assess the correlation between adverse events with blood group and dietary style. P < 0.05 is considered statistically significant. Results: The majority of the participants had comorbidities (80%) and were not infected with COVID (90%) before vaccination. Pain at the injection site is very frequently experienced followed by body aches, fatigue, fever, and weakness of the arm. The Chi-square correlation test showed that nonvegetarians had a significantly higher incidence of pain at the injection site compared to vegetarians [χ2 = 7.799, P < 0.004]. However, the study did not find a significant association between other adverse events with blood group and dietary style of the participants (P > 0.05). Conclusion: The present study concludes that study participants experienced minor adverse events following Covishield and Covaxin; pain at the injection site, myalgia, and fever are more frequent. Moreover, there is a higher incidence of injection site pain in nonvegetarians compared to vegetarians. However, there is no significant association between other adverse events with blood group and dietary style of the participants.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43628438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The best oils for cooking","authors":"Anita Teli","doi":"10.4103/jss.jss_103_22","DOIUrl":"https://doi.org/10.4103/jss.jss_103_22","url":null,"abstract":"","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46779955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}