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A Paradigm Shift in Prosthodontics: Analog to Digital 修复学的范式转变:模拟到数字
IF 0.3
Journal of the Scientific Society Pub Date : 2024-04-18 DOI: 10.4103/jss.jss_100_23
Sapna Rani, Pankaj Dhawan, Jigyasa Gupta, Juhi Singhla
{"title":"A Paradigm Shift in Prosthodontics: Analog to Digital","authors":"Sapna Rani, Pankaj Dhawan, Jigyasa Gupta, Juhi Singhla","doi":"10.4103/jss.jss_100_23","DOIUrl":"https://doi.org/10.4103/jss.jss_100_23","url":null,"abstract":"\u0000 Evolution happens in our everyday lifestyles in each field and prosthodontics is no exception to it. A new technology of sufferers is predicted to have new aspirations and desires. To fulfill these desires, it is our obligation to be updated with each expertise and capabilities about new developments in prosthodontics, so that these aspirations can be met. Although conventional techniques have worked satisfactorily for decades, with the growth of digital dentistry, conventional methods have become redundant. Digital methods are more accurate, efficient, less time-consuming, simpler, faster, and believed to have a better potential than conventional methods. This paper gives perception of trends and standards applied in modern prosthodontics and how they have an edge with the existing traditional or conventional methods used in the field.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140686894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proportion of Urinary Tract Infection in Children between 6 Months to 5 Years of Age Presenting with Fever 6 个月至 5 岁儿童尿路感染伴发热的比例
IF 0.3
Journal of the Scientific Society Pub Date : 2024-04-15 DOI: 10.4103/jss.jss_265_23
S. Mundada, Ayush Kumar
{"title":"Proportion of Urinary Tract Infection in Children between 6 Months to 5 Years of Age Presenting with Fever","authors":"S. Mundada, Ayush Kumar","doi":"10.4103/jss.jss_265_23","DOIUrl":"https://doi.org/10.4103/jss.jss_265_23","url":null,"abstract":"\u0000 \u0000 \u0000 Fever serves as the most frequent cause of visits to emergency/outpatient pediatric departments among children under the age of five. Very frequently, the youngster is given antibiotics on an arbitrary basis without receiving the proper examination for a urinary tract infection (UTI). This study’s goals were to assess the prevalence of UTIs in febrile children between 6 months and 5 years of age. To study the proportion of UTIs in children between 6 months and 5 years presenting with fever. To study the association of various risk factors with UTI.\u0000 \u0000 \u0000 \u0000 This Cross-sectional Descriptive observational research was done in the Pediatric department of tertiary care hospital from August 2020 to December 2022, in febrile kids between 6 months and 5 years age group using different variables. Association between two qualitative variables was seen by using Chi-square/Fischer’s exact test. A P < 0.05 was considered statistically significant whereas a P < 0.001 was considered highly significant.\u0000 \u0000 \u0000 \u0000 Among the total study population, it was found that 5.58% of the patients with fever without focus had a UTI, while the majority of patients, 94.42% did not have a UTI but had fever without a specific focus. In UTI cases, urine culture growth patterns showed the presence of different isolates, including Escherichia coli (30.43%), Klebsiella (56.52%), Pseudomonas aeruginosa (8.7%), and Candida (4.34%).\u0000 \u0000 \u0000 \u0000 In the present research, the overall occurrence of UTI in children <5 years with fever without focus was 5.58%. Patients with significant pyuria and positive urine culture (UTI) were 43.75% and with significant pyuria but the sterile culture was 56.25%. So, it is concluded that significant pyuria can be sterile pyuria and cannot be labeled as UTI without confirmation on the urine culture report.\u0000","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140699000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal Manifestation of Mixed Connective Tissue Disease 混合性结缔组织病的肾脏表现
IF 0.3
Journal of the Scientific Society Pub Date : 2024-03-14 DOI: 10.4103/jss.jss_74_20
Shalini Ashok, Meenakshi Kalyan, Vamsavardhan Reddy, S. Sumangala
{"title":"Renal Manifestation of Mixed Connective Tissue Disease","authors":"Shalini Ashok, Meenakshi Kalyan, Vamsavardhan Reddy, S. Sumangala","doi":"10.4103/jss.jss_74_20","DOIUrl":"https://doi.org/10.4103/jss.jss_74_20","url":null,"abstract":"\u0000 A young female presented with facial puffiness and swelling in both lower limbs for 3 months, distension of the abdomen, and breathlessness on exertion for 1 month with a history of hypertension and hypothyroid on regular treatment. On general physical examination, there were pallor, bilateral pitting edema, tachycardia, and blood pressure of 190/100 mmHg. Abdominal examination revealed shifting dullness. Respiratory and cardiovascular systems were normal. Fundoscopy revealed Grade 1 papilledema, and the rest of the neurological examination was unremarkable. Investigations showed normocytic normochromic anemia, serum creatinine of 1.6 mg/dl, and hypoalbuminemia; urine R/E showed significant proteinuria; and anti-U1 ribonucleoprotein particle antibodies were positive. Two-dimensional echocardiography showed mild concentric left ventricular hypertrophy and mild pericardial effusion. Ultrasonography abdomen showed bilateral renal parenchymal disease and moderate ascites. Renal biopsy revealed diffuse proliferative glomerulonephritis and lupus nephritis Class IV. Renal manifestation is very rare in mixed connective tissue disease as an initial presentation","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Study of COVID-19 Infection in Health-Care Workers Post-COVID Vaccination 医护人员接种 COVID 疫苗后感染 COVID-19 的研究
IF 0.3
Journal of the Scientific Society Pub Date : 2024-03-13 DOI: 10.4103/jss.jss_329_22
K. Kinge, Roshni C. Miranda, Priyanka Dnyanoba Chate
{"title":"The Study of COVID-19 Infection in Health-Care Workers Post-COVID Vaccination","authors":"K. Kinge, Roshni C. Miranda, Priyanka Dnyanoba Chate","doi":"10.4103/jss.jss_329_22","DOIUrl":"https://doi.org/10.4103/jss.jss_329_22","url":null,"abstract":"\u0000 \u0000 \u0000 Indian Council of Medical Research report in April 2021 showed the incidence of breakthrough infection ranged from 0.02% to 0.04%, in spite of immunization with the COVID vaccine. Hence, the current study was done to find out postvaccination occurrence of COVID-19 in health-care workers (HCWs) and describe the characteristics of postvaccination illness.\u0000 \u0000 \u0000 \u0000 The objectives of this study were to find out postvaccination COVID-19 illness characteristics such as severity, outcome, and required treatment in HCWs.\u0000 \u0000 \u0000 \u0000 An analytical cross-sectional study was conducted over the duration of 3 months from July to September 2021 on 988 HCWs. The data were collected using Google Forms made available on social media platforms. Continuous data were analyzed by Mann–Whitney test and categorical variables using the Chi-square test or Fisher’s exact test.\u0000 \u0000 \u0000 \u0000 Seventy-two (7.2%) out of 988 HCWs that participated in the study were tested COVID-19 positive (56.9% by reverse transcription–polymerase chain reaction, 38.9% by rapid antigen, and 4.16% by CBNAAT) postvaccination. The observed breakthrough infection was 3.84%. There were 18.3% and 5.6% cases of confirmed COVID-19 infection postpartial and complete vaccination, respectively (P = 0.000455). Those HCWs who had direct patient contact i. e., doctors and hospital staff 62 (6.7%) were more infected than other categories of HCWs (P = 0.010). Out of 72 cases who tested positive for COVID-19 infection, 52 were mild, 18 were moderate, and 2 were severe cases.\u0000 \u0000 \u0000 \u0000 Complete vaccination with two doses of the indigenous COVID vaccine is highly effective to bring down COVID illness-related hospitalization, severity, and death.\u0000","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140245739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical Fitness in Children with Thalassemia Major Measured With 6-min Walk Test 用 6 分钟步行测试测量重型地中海贫血症儿童的体能
IF 0.3
Journal of the Scientific Society Pub Date : 2024-02-19 DOI: 10.4103/jss.jss_129_23
T. Karthiga, G. Y. Imtiaz, S. Hariharan
{"title":"Physical Fitness in Children with Thalassemia Major Measured With 6-min Walk Test","authors":"T. Karthiga, G. Y. Imtiaz, S. Hariharan","doi":"10.4103/jss.jss_129_23","DOIUrl":"https://doi.org/10.4103/jss.jss_129_23","url":null,"abstract":"\u0000 \u0000 \u0000 Thalassemia major is a common type of genetic disorder found in improvement in the medical field, the life expectancy of these children was also increased so there arises a need to promote the quality of life of such patients. A lot of studies concentrate on various aspects of the life of thalassemia major, but no study was done to assess the physical fitness of such children which is quite important to regularize their exercise sessions.\u0000 \u0000 \u0000 \u0000 The objective of this study was to find out the physical fitness of children with thalassemia patients.\u0000 \u0000 \u0000 \u0000 Nonexperimental study designed with 20 individuals diagnosed with thalassemia in major age groups between 7 and 18 both boys and girls. The outcome measure used in this study was 6-min walk test (6 MWT).\u0000 \u0000 \u0000 \u0000 The mean distance covered in 6 min was 351.3 m on average. There was increase in heart rate and blood pressure after completion of the test, whereas oxygen saturation was found to drop post-6 MWT among these patients.\u0000 \u0000 \u0000 \u0000 Thalassemia major patients are found with this physical fitness when assessed with 6 MWT.\u0000","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140449928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective Observational Study on Drug Utilization in Renal Impaired Patients at Tertiary Care Teaching Hospital 关于三级教学医院肾功能受损患者药物使用情况的前瞻性观察研究
IF 0.3
Journal of the Scientific Society Pub Date : 2024-01-15 DOI: 10.4103/jss.jss_267_22
Varunsingh Saggu, Dhwani Patel, Cyril Sajan, Hemrajsingh Rajput, Rajesh Hadia
{"title":"A Prospective Observational Study on Drug Utilization in Renal Impaired Patients at Tertiary Care Teaching Hospital","authors":"Varunsingh Saggu, Dhwani Patel, Cyril Sajan, Hemrajsingh Rajput, Rajesh Hadia","doi":"10.4103/jss.jss_267_22","DOIUrl":"https://doi.org/10.4103/jss.jss_267_22","url":null,"abstract":"\u0000 \u0000 \u0000 Renal impairment is characterized by a progressive decline in glomerular filtration rate, a significant public health issue worldwide associated with high morbidity and mortality. In most cases, renal impairment is associated with comorbidities such as hypertension and diabetes, which require multiple drug therapy during a course of treatment, leading to polypharmacy.\u0000 \u0000 \u0000 \u0000 The objective of this study was to assess the prescribing pattern of drugs in renal-impaired patients at Dhiraj General Hospital.\u0000 \u0000 \u0000 \u0000 A total of 150 patients with renal impairment were finally recruited after strictly obeying the selection criteria in this cross-sectional, observational study conducted over 6 months in a tertiary care teaching hospital, directorate general of hydrocarbons. Relevant data were extracted by interviewing the patients and from prescriptions, case records, and investigational reports.\u0000 \u0000 \u0000 \u0000 Of the total 150 patients, 94 (63%) were male and 56 (37%) female. The highest numbers of patients were in the age group >60 years (59 patients, 39.3%). Anemia was the most common comorbidity (143 patients, 95%) observed, followed by hypertension (129 patients, 86%) and diabetes mellitus (64 patients, 43%). A total of 1693 drugs were prescribed to 150 renal-impaired patients. Each patient received an average of 11.19 ± 3.51 (8%) drugs. Polypharmacy was seen in all patients. Drugs acting on the cardiovascular system constituted the bulk of the prescriptions (25.87%), followed by gastrointestinal (GI) drugs (18.72%), vitamins and minerals (14.94%), and antibiotics (8.33%).\u0000 \u0000 \u0000 \u0000 There is polypharmacy in patients with renal impairment due to associated comorbidities. The prevalence of polypharmacy was high in patients with chronic kidney disease (CKD). Antihypertensive drugs, drugs used for the GI system, antibiotics, and antidiabetic drugs were frequently used in CKD patients.\u0000","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139622548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral venous sinus thrombosis 脑静脉窦血栓形成
IF 0.3
Journal of the Scientific Society Pub Date : 2023-09-01 DOI: 10.4103/jss.jss_294_22
Cyril Sajan, Varunsingh Saggu, Maitri Mahant, Dilsar Gohel, Foram Bhatt, Elizabeth Jacob
{"title":"Cerebral venous sinus thrombosis","authors":"Cyril Sajan, Varunsingh Saggu, Maitri Mahant, Dilsar Gohel, Foram Bhatt, Elizabeth Jacob","doi":"10.4103/jss.jss_294_22","DOIUrl":"https://doi.org/10.4103/jss.jss_294_22","url":null,"abstract":"Cerebral venous sinus thrombosis (CVST) is a relatively uncommon but important cause of stroke-like disease, accounting for fewer than 1% of all strokes. CVST is more common in females and infants. CVST patients are most common in the third decade, with a female-to-male ratio of 5:1.5. The incidence of CVST has been found to be high in developing countries, particularly in South-East Asia. Headache is the most prevalent clinical sign of CVST, occurring in 88% to 93% of patients, followed by a seizure in 37% to 71%, focal neurological deficit in 20% to 54%, and isolated increased intracranial pressure in 23%.[1] A 34-year-old male came to the tertiary care hospital with complaints of headache, vomiting, and vertigo for 1 day. Headache is insidious, progressive, nonradiating, holocephalic, severe in intensity and associated with vertigo and dizziness, and giddiness, he also complained about nausea and vomiting (10–12 episodes/day) containing food and water. The patient had no family history but has been chronic tobacco chewer for 10 years. Past medical history revealed that he was admitted to the hospital before for the same complaints and he also had right lower vein deep-vein thrombosis 6 months back. His magnetic imaging resonance reports and protein S and C deficiency reports revealed that he was suffering from CVST. He was prescribed with anticoagulants and other supportive treatments that include antiemetic, analgesics, and multivitamins, which cause faster and better recovery of patients.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139345211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Training medical students in cognitive, intrapersonal, and interpersonal domain competencies: Existing challenges and role of medical teachers 对医学生进行认知、个人和人际领域能力的培训:现有挑战和医学教师的作用
IF 0.3
Journal of the Scientific Society Pub Date : 2023-09-01 DOI: 10.4103/jss.jss_178_22
Saurabh Ram Bihari Shrivastava, Mira Duan Raharjo, Bayu Pratama, Tasi'ah Nur, Nurul Maziyyah, K. Pratidina, Achcia Maliny, Yanuarti Retnaningrum
{"title":"Training medical students in cognitive, intrapersonal, and interpersonal domain competencies: Existing challenges and role of medical teachers","authors":"Saurabh Ram Bihari Shrivastava, Mira Duan Raharjo, Bayu Pratama, Tasi'ah Nur, Nurul Maziyyah, K. Pratidina, Achcia Maliny, Yanuarti Retnaningrum","doi":"10.4103/jss.jss_178_22","DOIUrl":"https://doi.org/10.4103/jss.jss_178_22","url":null,"abstract":"The medical students of the current generation are expected to perform a wide range of activities targeted toward the acquisition of a multitude of skills and the attainment of various learning competencies. The purpose of the current review is to explore the challenges in the cognitive, interpersonal, and intrapersonal domains, and to propose an educational plan to respond to the challenges defined in the cognitive domain. An extensive search of all materials related to the topic was carried out on the PubMed and Google Scholar search engines and a total of 39 articles were selected based on their suitability with the current review objectives. Keywords used in the search include critical thinking and medical education in the title alone only. The findings of a committee reported that a successful health-care professional will essentially require competence in three domains, namely cognitive, intrapersonal, and interpersonal domain. However, the careful analysis of the medical education delivery system across different parts of the world suggests that we are falling short in our efforts to adequately expose medical students' to these competencies. In the global mission to improve the quality of health-care delivery, we have to take specific measures to ensure the attainment of the desired competencies, and the involvement of teachers will be crucial. In conclusion, considering the dynamism in the health sector, it is the responsibility of educators to enhance the attainment of cognitive competencies of the students. Further, students should be encouraged to reflect, and experiential learning should be regularly practiced to equip the students with intrapersonal skills. Finally, we also have to focus on the attainment of interpersonal competencies, as it prepares them to work as effective members of the team.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139343855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Newer prospects of regenerative endodontics: A comprehensive and updated review of literature 再生牙髓学的新前景:全面、最新的文献综述
IF 0.3
Journal of the Scientific Society Pub Date : 2023-09-01 DOI: 10.4103/jss.jss_214_22
M. Khan, M. Jindal
{"title":"Newer prospects of regenerative endodontics: A comprehensive and updated review of literature","authors":"M. Khan, M. Jindal","doi":"10.4103/jss.jss_214_22","DOIUrl":"https://doi.org/10.4103/jss.jss_214_22","url":null,"abstract":"In pediatric dental patients, the management of nonvital immature teeth with undeveloped root in endodontic practice pose difficult and cumbersome clinical situations or challenges for the dental practitioners owing to the various factors, namely, the shorter root with thinner dentinal walls and the lack of apical closure make the affected tooth difficult to obturate conventionally and also make more vulnerable to root fracture. Conventionally, apexification and later apical barrier/plug endodontic modalities have been widely undertaken for such affected teeth. However, such treatment approaches have several intrinsic shortcomings such as uncertain long-term treated tooth prognosis. Since recent years, a biologically based therapeutic endodontic approach known as regenerative endodontic therapy has been or being extensively explored or studied to overcome the drawbacks of previous conventional treatment modalities and also to improve the long-term prognosis of the affected immature nonvital teeth in children and adolescents. Regenerative endodontics is a rapidly evolving subject and also a promising treatment modality for the scientific researchers and clinicians, respectively. Hence, the present article aims to comprehensively and critically appraise the recent literature pertaining to regenerative endodontic procedures. The relevant literature regarding the regenerative endodontics was searched in electronic databases. The articles were retrieved using Boolean operators with relevant keywords/Medical Subject Headings. The included relevant articles were critically appraised in the present review. The latest important aspects of regenerative endodontic have been described in a systematic manner for its better understanding and deeper insights for the general and pediatric dental professionals.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139343860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of serum prostate-specific antigen with gleason's score/grade group in prostate cancers and their histopathological findings: A 4-year retrospective study at a tertiary care center 前列腺癌患者血清前列腺特异性抗原与格里森评分/分级组及其组织病理学结果的相关性:一家三级医疗中心的四年回顾性研究
IF 0.3
Journal of the Scientific Society Pub Date : 2023-09-01 DOI: 10.4103/jss.jss_75_22
Ritu Sharma, Megha Bansal, H. Sharma, Nikhilesh Kumar, Vinish, Monika Gupta, Manju Sirohi
{"title":"Correlation of serum prostate-specific antigen with gleason's score/grade group in prostate cancers and their histopathological findings: A 4-year retrospective study at a tertiary care center","authors":"Ritu Sharma, Megha Bansal, H. Sharma, Nikhilesh Kumar, Vinish, Monika Gupta, Manju Sirohi","doi":"10.4103/jss.jss_75_22","DOIUrl":"https://doi.org/10.4103/jss.jss_75_22","url":null,"abstract":"Background: Prostate-specific antigen (PSA) has been widely used as a screening method in different prostatic pathology including prostate cancer. The malignant potential of prostate cancer is associated with tumor volume at diagnosis and studies of the correlation between serum PSA levels and Gleason's grading which remains one of the most powerful predictors of prostate cancer. Aim: To correlate serum PSA and Gleason's score/Group grade in various neoplastic prostatic biopsies and to study their histopathological findings at a tertiary care center. Materials and Methods: This study uses PSA as a screening tool and to correlate serum PSA level to Gleason scores/group grades in various neoplastic and nonneoplastic prostatic biopsies, received at the Department of Pathology, T. S. Misra Medical College and Hospital, Lucknow during 4 years from June 2016 to July 2020. Results: The mean serum PSA value in benign prostatic hyperplasia (BPH) without prostatitis cases was 1.80 ng/ml and BPH with prostatitis was 5.86 and in malignant cases was 55.2 ng/ml. Serum PSA in the range of 0–4 ng/ml was significantly associated with benign lesions and a value of more than 20 ng/ml was significantly associated with malignant lesions. The most frequent Gleason score was 7 and Grade group II was the highest in number. The highest incidence of malignancies and prostatic hyperplasia occurred among the 60–69 years of age group. PSA values increased significantly (P < 0.05) in prostatic carcinoma cases (Group grade II and III). Conclusion: PSA is a valid, sensitive, and early screening method for the diagnosis of both neoplastic and nonneoplastic lesions of the prostate. PSA values correlated significantly with Gleason's score/grade groups of prostatic carcinoma.","PeriodicalId":55681,"journal":{"name":"Journal of the Scientific Society","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139345429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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