American Journal of Geriatric Psychiatry最新文献

{"title":"Curmudgeon","authors":"Nancy R. Davison PhD","doi":"10.1016/j.jagp.2024.12.004","DOIUrl":"10.1016/j.jagp.2024.12.004","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 4","pages":"Page 483"},"PeriodicalIF":4.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Subscribers","authors":"","doi":"10.1016/S1064-7481(24)00517-7","DOIUrl":"10.1016/S1064-7481(24)00517-7","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Page A1"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143141032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychedelics in Older Adults: Difficulties of a Clear Therapeutic Evidence","authors":"Melissa Cortez Braga Maia , Lucas Lima Menezes Albuquerque , Adriana Araujo Oliveira , Manoel Roberto Franco Ramos Neto , Lia Mesquita de Abreu , Fábio Gomes de Matos e Souza , Luísa Weber Bisol","doi":"10.1016/j.jagp.2024.07.008","DOIUrl":"10.1016/j.jagp.2024.07.008","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 116-117"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guest Editorial: Wisdom-Focused Intervention Reduces Loneliness: Proposing an Evolutionary Basis for Wisdom and Social Cooperation to Reduce Loneliness in the Homo sapiens","authors":"Dilip V. Jeste M.D. , Mei-Hua Hall Ph.D.","doi":"10.1016/j.jagp.2024.07.009","DOIUrl":"10.1016/j.jagp.2024.07.009","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 31-33"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141969726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late Life Depression is Not Associated With Alzheimer-Type Tau: Preliminary Evidence From a Next-Generation Tau Ligand PET-MR Study","authors":"Thomas Vande Casteele M.D. ,&nbsp;Maarten Laroy M.Sc. ,&nbsp;Margot Van Cauwenberge M.D. ,&nbsp;Greet Vanderlinden M.Sc. ,&nbsp;Kristof Vansteelandt M.Sc. ,&nbsp;Michel Koole Ph.D. ,&nbsp;Patrick Dupont Ph.D. ,&nbsp;Maarten Van Den Bossche M.D., Ph.D. ,&nbsp;Jan Van den Stock Ph.D. ,&nbsp;Filip Bouckaert M.D., Ph.D. ,&nbsp;Koen Van Laere M.D., Ph.D. ,&nbsp;Louise Emsell Ph.D. ,&nbsp;Mathieu Vandenbulcke M.D., Ph.D.","doi":"10.1016/j.jagp.2024.07.005","DOIUrl":"10.1016/j.jagp.2024.07.005","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate whether tau accumulation is higher in late life depression (LLD) compared to non-depressed cognitively unimpaired (CU) older adults. To situate these findings in the neurodegeneration model of LLD by assessing group differences in tau and grey matter volume (GMV) between LLD, non-depressed CU and mild cognitive impairment due to Alzheimer's Disease (MCI).</div></div><div><h3>Design</h3><div>Monocentric, cross-sectional study.</div></div><div><h3>Setting</h3><div>University Psychiatric hospital, memory clinic and outpatient neurology practice.</div></div><div><h3>Participants</h3><div>A total of 102 adults over age 60, of whom 19 currently depressed participants with LLD, 19 with MCI and 36 non-depressed CU participants completed neuropsychological testing and tau PET-MR imaging.</div></div><div><h3>Measurements</h3><div>PET-MRI: 18F-MK-6240 tracer SUVR for tau assessment; 3D T1-weighted structural MRI derived GMV in seven brain regions (temporal, cingulate, prefrontal and parietal regions); amyloid PET to assess amyloid positivity; Neuropsychological test scores: MMSE, RAVLT, GDS, MADRS. ANCOVA and Spearman's rank correlations to investigate group differences in tau and GMV, and correlations with neuropsychological test scores respectively.</div></div><div><h3>Results</h3><div>Compared to non-depressed CU participants, LLD patients showed lower GMV in temporal and anterior cingulate regions but similar tau accumulation and amyloid positivity rate. In contrast, MCI patients had significantly higher tau accumulation in all regions. Tau did not correlate with any neuropsychological test scores in LLD.</div></div><div><h3>Conclusion</h3><div>Our findings suggest AD-type tau is not higher in LLD compared to non-depressed, cognitively unimpaired older adults and appears unlikely to contribute to lower gray matter volume in LLD, further underscoring the need to distinguish major depressive disorder from depressive symptoms occurring in early AD.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 47-62"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141852317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life Fatigue: Comment","authors":"Hinpetch Daungsupawong Ph.D.,&nbsp;Viroj Wiwanitkit M.D.","doi":"10.1016/j.jagp.2024.09.012","DOIUrl":"10.1016/j.jagp.2024.09.012","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 112-113"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Vishnu Schist","authors":"David L. Coulter M.D.","doi":"10.1016/j.jagp.2023.12.003","DOIUrl":"10.1016/j.jagp.2023.12.003","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Page 121"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138579309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National VA Data Indicate Need for Research and Interventions for PTSD in Skilled Nursing Facilities","authors":"Amber Gum Ph.D.","doi":"10.1016/j.jagp.2024.07.019","DOIUrl":"10.1016/j.jagp.2024.07.019","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 44-46"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141997023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the Letter on “Life Fatigue: A Critical Analysis”","authors":"Margarita Bofarull M.D., M.A.,&nbsp;Montse Esquerda M.D., Ph.D.,&nbsp;David Lorenzo Ph.D.","doi":"10.1016/j.jagp.2024.10.001","DOIUrl":"10.1016/j.jagp.2024.10.001","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 114-115"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Disorder in Older Veterans admitted to VA Community Living Centers: Prevalence and Risk Correlates","authors":"Kelly O'Malley Ph.D. ,&nbsp;Jennifer Moye Ph.D. ,&nbsp;Jianwei Leng M.Stat ,&nbsp;Zachary Burningham Ph.D.","doi":"10.1016/j.jagp.2024.07.014","DOIUrl":"10.1016/j.jagp.2024.07.014","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine prevalence and risk correlates for post-traumatic stress disorder (PTSD) occurring during or after admission to a Veterans Administration (VA) skilled nursing facility.</div></div><div><h3>Design</h3><div>Retrospective cohort analysis of electronic health record information extracted from the VA Corporate Data Warehouse.</div></div><div><h3>Setting</h3><div>United States VA skilled nursing facility.</div></div><div><h3>Participants</h3><div>57,414 Veterans age 60+ with an admission during five fiscal years, 2018–2022, excluding those who died within six months of admission or were still admitted.</div></div><div><h3>Measurements</h3><div>The dependent variable was PTSD diagnosis during or six-months following the admission. Risk correlates examined were: age, gender, race, rurality, clinical complexity, prior dementia diagnosis, length of stay, and facility size; odds ratios (OR) and confidence intervals (CI) are provided for each correlate.</div></div><div><h3>Results</h3><div>19.1% of Veterans had a diagnosis of PTSD, associated with younger age (age 60–69 compared to age 80+; OR: 2.92, 95% CI: 2.70–3.14; age 70–79 compared to age 80+ OR: 4.51, 95% CI: 4.20–4.84); female gender (OR: 1.65, 95% CI: 1.50–1.82); minoritized race (OR: 1.17, 95% CI: 1.12–1.23); higher clinical complexity (OR:1.22, 95% CI: 1.17–1.28). As compared to Veterans who had a prior PTSD diagnosis, Veterans with newly diagnosed PTSD were more likely to be older (age 60 group OR= 0.59, 95% CI:0.51–0.70; age 70 group OR= 0.54, 95% CI:0.46–0.62,), rural (OR=1.14, 95% CI:1.04–1.24) and admitted to a larger facility (OR=1.22, 95% CI:1.12–1.33).</div></div><div><h3>Conclusions</h3><div>PTSD is a significant concern for older Veterans admitted to VA skilled nursing facilities, supporting the need for trauma-informed care, particularly for those most at risk.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 1","pages":"Pages 34-43"},"PeriodicalIF":4.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}