American Journal of Geriatric Psychiatry最新文献

{"title":"Information for Subscribers","authors":"","doi":"10.1016/S1064-7481(25)00514-7","DOIUrl":"10.1016/S1064-7481(25)00514-7","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Page A1"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to “The Evidence Base for Electroconvulsive Therapy (ECT) in Geriatric Depression”","authors":"Tor Arnison Ph.D. , Axel Nordenskjöld M.D., Ph.D.","doi":"10.1016/j.jagp.2025.07.015","DOIUrl":"10.1016/j.jagp.2025.07.015","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 136-137"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144986956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evidence Base for Electroconvulsive Therapy (ECT) in Geriatric Depression","authors":"Charles H. Kellner M.D. , Alexander Sartorius M.D., Ph.D. , Randall T. Espinoza M.D., M.P.H.","doi":"10.1016/j.jagp.2025.06.021","DOIUrl":"10.1016/j.jagp.2025.06.021","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 134-135"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144719376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ketamine for Late-Life Depression: Where Do We Stand?","authors":"Hanadi Ajam Oughli M.D. , Marie Anne Gebara M.D. , Alastair J. Flint M.B.","doi":"10.1016/j.jagp.2025.09.008","DOIUrl":"10.1016/j.jagp.2025.09.008","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 103-105"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145295041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invited Perspective on “Daily Associations Between Caregiving Time and Spousal Caregivers' Well-Being: The Moderating Roles of Daily Marital Interactions.” (Yang et al. 2025)","authors":"Rose Lin Ph.D., Maria M. Quiñones-Cordero Ph.D.","doi":"10.1016/j.jagp.2025.09.009","DOIUrl":"10.1016/j.jagp.2025.09.009","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 28-30"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145305254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Ratio of Triglycerides to HDL-C and Cognitive Impairment: A Longitudinal Population-Based Analysis and Mendelian Randomization Study","authors":"Yucheng Huang M.B.B.S. ,&nbsp;Lijia Zheng M.P.H. ,&nbsp;Meng-Meng Lyu Ph.D.","doi":"10.1016/j.jagp.2025.08.007","DOIUrl":"10.1016/j.jagp.2025.08.007","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to explore the longitudinal association between the triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and cognitive impairment in older adults and further assess potential causality using Mendelian randomization (MR).</div></div><div><h3>Design</h3><div>Longitudinal population-based analysis combined with two-sample MR. Data from Waves 6–8 (2015–2019) of the Survey of Health, Ageing, and Retirement in Europe (SHARE) were analyzed using hierarchical regression models and mixed linear effects models. MR utilized genome-wide association studies (GWAS) summary data.</div></div><div><h3>Participants</h3><div>11,444 adults aged ≥60 years from SHARE Wave 6, with longitudinal follow-up in Waves 7 (<em>N</em> = 2,775) and 8 (<em>N</em> = 5,469).</div></div><div><h3>Measurements</h3><div>TG/HDL-C ratio, cognitive function (orientation, immediate/delayed recall, verbal fluency, numeracy), and cognitive impairment (defined as scores &gt;1.5 SD below age-group mean). Covariates included socio-demographics, health behaviors, comorbidities, and national-level factors. MR employed genetic variants associated with TG/HDL-C as instrumental variables.</div></div><div><h3>Results</h3><div>Higher TG/HDL-C ratios were negatively associated with total cognitive scores (β = −0.115, χ² = 15.44, df = 1, p &lt; 0.001), immediate recall (β = −0.029, χ² = 12.34, df = 1, p &lt; 0.001), delayed recall (β = −0.028, χ² = 7.33, df = 1, p &lt; 0.001), verbal fluency (β = −0.038, χ² = 11.53, df = 1, p &lt; 0.001), and numeracy (β = −0.019, χ² = 4.55, df = 1, p &lt; 0.05) in fully adjusted models. Longitudinal analysis revealed increased cognitive impairment risk in the highest TG/HDL-C quartile (OR=1.43, 95% CI:1.01–2.03, χ² = 9.24, df = 1) over 4 years. MR supported a causal link between elevated TG/HDL-C and cognitive decline.</div></div><div><h3>Conclusions</h3><div>Elevated TG/HDL-C ratios are longitudinally associated with cognitive decline in older adults. Managing lipid metabolism may mitigate cognitive impairment, highlighting the importance of TG/HDL-C as a modifiable risk factor in aging populations.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 1-14"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Silencing of Science is a Call for Communications","authors":"Joseph K. Balintfy BA","doi":"10.1016/j.jagp.2025.10.007","DOIUrl":"10.1016/j.jagp.2025.10.007","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 123-126"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgment of Triage Editors and Reviewers 2025","authors":"Charles F. Reynolds III M.D.","doi":"10.1016/j.jagp.2025.09.022","DOIUrl":"10.1016/j.jagp.2025.09.022","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"34 1","pages":"Pages 113-116"},"PeriodicalIF":3.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avoiding Stigma and Sensationalism in Therapeutic Psilocybin Communications: Considerations for Reaching Older Patients","authors":"Charlotte M. Gillespie MSc,&nbsp;Jesse M. Bering PhD","doi":"10.1016/j.jagp.2025.07.003","DOIUrl":"10.1016/j.jagp.2025.07.003","url":null,"abstract":"<div><div>Psilocybin’s efficacy as a treatment for treatment-resistant depression (TRD) has led to a wave of new legislation permitting its usage in medical settings. Older adults are affected disproportionately by TRD and may be especially good candidates for this promising treatment. However, due to the drug’s past (and present) illicit status and exposure to historic antidrug messaging, older prospective patients may hold more stigmatized attitudes towards this treatment than those who are younger. Stigma and sensationalism pose special challenges for the dissemination of effective, accurate information about therapeutic psilocybin, with recent “hype” around the drug treatment possibly further alienating these individuals. Because current clinical communication strategies may be inadvertently reinforcing negative attitudes about psychedelics rather than reducing them, we offer some general communication guidelines for therapeutic psilocybin geared towards the older patient profile.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 12","pages":"Pages 1251-1259"},"PeriodicalIF":3.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144885034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Current State of International Human Rights of Older Persons","authors":"Robert Kohn M.D.","doi":"10.1016/j.jagp.2025.08.004","DOIUrl":"10.1016/j.jagp.2025.08.004","url":null,"abstract":"<div><div>The UN has produced various declarations addressing the human rights of older persons. The UN does not have a specific treaty or convention regarding human rights of older persons as part of its human rights system. Recently the Open-ended Working Group on Ageing has recommended to the General Assembly to adopt a binding convention on human rights for older persons. There has been progress already at the regional level. The European Convention of Human Rights Article 23 has been ratified by less than half the countries. The African Charter on Human and Peoples’ Rights is the first human rights instrument to include older persons as a distinct group. In November 2024 a protocol on older persons human rights was adopted. The Organization of American States adopted the Inter-American Convention on Protecting the Human Rights of Older Persons, the first human rights document specific to older persons and the only legally binding instrument. Although progress has been made on focusing on human rights on older persons, a binding UN international convention on human rights of older persons would be a tool to improve dignified mental healthcare.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 12","pages":"Pages 1322-1330"},"PeriodicalIF":3.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145067575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}