American Journal of Geriatric Psychiatry最新文献

{"title":"Information for Subscribers","authors":"","doi":"10.1016/S1064-7481(25)00321-5","DOIUrl":"10.1016/S1064-7481(25)00321-5","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 7","pages":"Page A1"},"PeriodicalIF":4.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A “View” and a Gift","authors":"Eran Metzger M.D. , Donna M Fick R.N., Ph.D.","doi":"10.1016/j.jagp.2025.05.002","DOIUrl":"10.1016/j.jagp.2025.05.002","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 7","pages":"Pages 806-808"},"PeriodicalIF":4.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fair Science Frowned Not: An Elegy for a Lost World","authors":"David L. Coulter M.D.","doi":"10.1016/j.jagp.2025.04.211","DOIUrl":"10.1016/j.jagp.2025.04.211","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 7","pages":"Pages 815-817"},"PeriodicalIF":4.4,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerometer-Derived Physical Activity, Sedentary Behavior, and the Risk of Depression and Anxiety.","authors":"Vincent E S Allott, Benjamin H L Harris, Michael B Fertleman, Louis J Koizia","doi":"10.1016/j.jagp.2025.04.209","DOIUrl":"https://doi.org/10.1016/j.jagp.2025.04.209","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network Analysis of Delusion Subtypes in Amyloid PET-Positive, Drug-Naïve Alzheimer's Disease Patients.","authors":"Youngsoon Yang, Yong Tae Kwak","doi":"10.1016/j.jagp.2025.04.210","DOIUrl":"https://doi.org/10.1016/j.jagp.2025.04.210","url":null,"abstract":"<p><strong>Objectives: </strong>To identify the distinct delusional subtypes in drug-naïve, amyloid PET-positive Alzheimer's disease (AD) and analyze their interrelationships via network analysis.</p><p><strong>Design: </strong>Cross-sectional observational study.</p><p><strong>Setting: </strong>A dementia clinic at Soonchunhyang University Cheonan Hospital in South Korea, which maintains a comprehensive dementia registry.</p><p><strong>Participants: </strong>One hundred two patients with mild-to-moderate, amyloid PET-positive AD who exhibited delusions on the Korean Neuropsychiatric Inventory (K-NPI).</p><p><strong>Measurements: </strong>Delusional subtypes were defined using the K-NPI; global cognitive function was measured by the Korean Mini-Mental State Examination (K-MMSE). Network analysis examined central (hub) and bridging symptoms.</p><p><strong>Results: </strong>Theft delusion was the most frequent subtype (89.2%), followed by reduplicative paramnesia (46.1%). Network analysis identified reduplicative paramnesia as the most central delusion, strongly linked to others, while theft delusion also emerged as a central node. Infidelity delusion was peripheral and negatively correlated with theft delusion, suggesting distinct etiological pathways. No significant associations were found between any subtype and K-MMSE scores. Stability metrics supported the robustness of these interconnections.</p><p><strong>Conclusions: </strong>In amyloid PET-positive, drug-naïve AD, paranoid and spatial misidentification themes-particularly reduplicative paramnesia-appear highly interconnected and may share underlying pathophysiological processes. Targeting core misinterpretation and paranoia (e.g., via consistent environmental cues or focused cognitive strategies) could potentially alleviate multiple delusional themes. In contrast, jealousy-driven beliefs may require more interpersonal or relational interventions. Further longitudinal research is needed to clarify how these networks evolve with advancing disease and whether core nodes shift as global cognition declines.</p>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Subscribers","authors":"","doi":"10.1016/S1064-7481(25)00096-X","DOIUrl":"10.1016/S1064-7481(25)00096-X","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 6","pages":"Page A1"},"PeriodicalIF":4.4,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily Life Stressors in Long Term Care: A View From the Inside","authors":"Dan G. Blazer M.D., M.P.H., Ph.D.","doi":"10.1016/j.jagp.2025.03.013","DOIUrl":"10.1016/j.jagp.2025.03.013","url":null,"abstract":"<div><div>Frequent questions arise from residents and their families/friends in long term care regarding their care and comfort. These questions are usually, though not always, directed primarily to the nursing staff and therefore are not available to geriatric psychiatrists who care for these residents. The author of this essay is now an independent living resident in a continuing care community. He has assumed the role of chair of the Resident’s Health Committee. In this position his eyes have been opened to many daily life experiences in long-term care. Given the typical focus of the psychiatric interview in such facilities, these questions often do not reach the ears of clinicians.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 7","pages":"Pages 801-805"},"PeriodicalIF":4.4,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Landscape of Intensive Outreach Services for Older Adults With Serious Mental Illness: A Scoping Review.","authors":"Claire Stanley, Andrew Namasivayam, Sarah Colman, Vicky Stergiopoulos","doi":"10.1016/j.jagp.2025.04.208","DOIUrl":"https://doi.org/10.1016/j.jagp.2025.04.208","url":null,"abstract":"<p><p>Older adults living with mental illness, particularly those with serious mental illness (SMI), represent a vulnerable and underserved patient population. Deinstitutionalization laid the groundwork for intensive outreach services for this population, yet little attention was paid to the unique needs of older individuals with SMI. We conducted a scoping literature review to map the landscape of intensive outreach services developed for older adults living with SMI. We specifically focused on peer-reviewed literature. EMBASE, MEDLINE, PsycINFO and CINAHL databases were searched for pertinent literature between 1990 and 2023. Fourteen studies were selected for inclusion from 2,952 articles screened. Most studies were descriptive (N = 7). There were three randomized controlled trials (N = 3), three quasi-experimental studies (N = 3) and one (N = 1) pre-experimental study. All programs had a multidisciplinary component with a wide range of allied health clinicians. Six programs were adapted from the assertive community treatment model. Three programs included medical specialists. Only seven studies focused on examining treatment outcomes or efficacy, though there was notable variability in outcome measures analyzed. While intensive outreach services for older adults with SMI show promise, this scoping review highlights the paucity of research in this area. Future research rigorously evaluating models of care, with emphasis on fidelity, cost-effectiveness and patient outcomes, will be essential to inform service delivery to this population.</p>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial and Ethnic Disparities in the 11-Year Bidirectional Relationship Between Dementia and Social Isolation Among Community-Dwelling Older Adults.","authors":"Tianxue Hou, Minhui Liu, Bei Wu, Mu-Hsing Ho, Chia-Chin Lin","doi":"10.1016/j.jagp.2025.03.014","DOIUrl":"https://doi.org/10.1016/j.jagp.2025.03.014","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the longitudinal impact of dementia on social isolation and vice versa, with a focus on racial and ethnic variations in these relationships.</p><p><strong>Methods: </strong>Data from 4,403 adults aged 65 and older were gathered from the National Health and Aging Trends Study (2011-2021). Dementia was categorized as no, possible, or probable, and social isolation was classified as socially isolated or not. Two cohorts were formed based on baseline social isolation and baseline dementia status. Cox proportional hazards regression models were used to evaluate the impact of baseline social isolation on subsequent dementia and vice versa, adjusting for potential covariates. Models were stratified by race/ethnicity. All analyses were conducted using STATA/MP version 17.0 RESULTS: In fully adjusted models, participants with dementia had a 1.40-fold higher likelihood of developing social isolation over the 10-year follow-up period. Those with baseline social isolation had a 7.21-fold higher likelihood of developing dementia over time. Racial and ethnic differences were observed in the influence of dementia on social isolation incidence. Non-Hispanic whites showed a statistically significant increase, while other racial and ethnic groups did not exhibit significant changes. Conversely, the impact of social isolation on dementia incidence was significant across all racial and ethnic groups.</p><p><strong>Discussion: </strong>Dementia and social isolation are bidirectionally linked among older adults, with notable racial and ethnic differences. Dementia increases the risk of social isolation, particularly among non-Hispanic whites, while social isolation significantly elevates the risk of developing dementia across all racial and ethnic groups. These findings underscore the need for targeted interventions to address social isolation and cognitive decline, considering racial and ethnic differences to improve outcomes for seniors.</p>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive Symptoms Correlate With Tau Accumulation Rates in Amyloid Positive Adults","authors":"Daniel Talmasov M.D. ,&nbsp;Aubrey S. Johnson B.A. ,&nbsp;Patrick J. Brown Ph.D. ,&nbsp;Frank A. Provenzano Ph.D. ,&nbsp;Patrick J. Lao Ph.D. ,&nbsp;Karen S. Marder M.D. ,&nbsp;Jeffrey M. Miller M.D. ,&nbsp;for the Alzheimer’s Disease Neuroimaging Initiative","doi":"10.1016/j.jagp.2025.04.207","DOIUrl":"10.1016/j.jagp.2025.04.207","url":null,"abstract":"<div><h3>Objective</h3><div>Depression in Alzheimer’s disease (AD) is linked to faster cognitive decline and increased tau pathology. This study examines the relationship between depressive symptoms and tau accumulation rates in older adults from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database.</div></div><div><h3>Methods</h3><div>Three-hundred and three ADNI participants with normal cognition, mild cognitive impairment, or dementia underwent serial [18F]-flortaucipir tau positron-emission tomography (PET) between 2015 and 2022. We assessed whether the Geriatric Depression Scale (GDS) score between baseline and final PET scans correlated with rates of tau accumulation in a temporal lobe meta-region of interest.</div></div><div><h3>Results</h3><div>GDS score was positively correlated with annualized tau accumulation rates in models adjusted for baseline tau burden, amyloid status on PET, and APOE genotype. This correlation was observed in amyloid-positive, but not amyloid-negative, participants.</div></div><div><h3>Conclusion</h3><div>Depressive symptoms in amyloid-positive adults correlate with accelerated tau accumulation, suggesting that depression may have particular relevance as an indicator of AD pathology progression, and represents a target for future research into modifiable risk factors in AD.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 7","pages":"Pages 756-769"},"PeriodicalIF":4.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}