American Journal of Geriatric Psychiatry最新文献

{"title":"Long-Term Impact of Delirium on the Risk of Dementia in Hospitalized Older Patients: A Real-World Multicenter Study","authors":"Gyubeom Hwang M.D. ,&nbsp;ChulHyoung Park M.D. ,&nbsp;Sang Joon Son M.D., Ph.D. ,&nbsp;Hyun Woong Roh M.D., Ph.D. ,&nbsp;Jae Yeon Hwang M.D., Ph.D. ,&nbsp;Jae-Won Jang M.D., Ph.D. ,&nbsp;Young Tak Jo M.D., Ph.D. ,&nbsp;Gihwan Byeon M.D. ,&nbsp;HyunChul Youn M.D., Ph.D. ,&nbsp;Rae Woong Park M.D., Ph.D.","doi":"10.1016/j.jagp.2024.08.004","DOIUrl":"10.1016/j.jagp.2024.08.004","url":null,"abstract":"<div><h3>Background</h3><div>The association between delirium and dementia has been suggested, but mostly in the postoperative setting. This study aims to explore this relationship in a broader inpatient population, leveraging extensive real-world data to provide a more generalized understanding.</div></div><div><h3>Methods</h3><div>In this retrospective cohort study, electronic health records of 11,970,475 hospitalized patients aged over 60 from nine institutions in South Korea were analyzed. Patients with and without delirium were identified, and propensity score matching (PSM) was used to create comparable groups. A 10-year longitudinal analysis was conducted using the Cox proportional hazards model, which calculated the hazard ratio (HR) and 95% confidence interval (CI). Additionally, a meta-analysis was performed, aggregating results from all nine medical institutions. Lastly, we conducted various subgroup and sensitivity analyses to demonstrate the consistency of our study results across diverse conditions.</div></div><div><h3>Results</h3><div>After 1:1 PSM, a total of 47,306 patients were matched in both the delirium and nondelirium groups. Both groups had a median age group of 75–79 years, with 43.1% being female. The delirium group showed a significantly higher risk of all dementia compared with the nondelirium group (HR: 2.70 [95% CI: 2.27–3.20]). The incidence risk for different types of dementia was also notably higher in the delirium group (all dementia or mild cognitive impairment, HR: 2.46 [95% CI: 2.10–2.88]; Alzheimer's disease, HR: 2.74 [95% CI: 2.40–3.13]; vascular dementia, HR: 2.55 [95% CI: 2.07–3.13]). This pattern was consistent across all subgroup and sensitivity analyses.</div></div><div><h3>Conclusions</h3><div>Delirium significantly increases the risk of onset for all types of dementia. These findings highlight the importance of early detection of delirium and prompt intervention. Further research studies are warranted to investigate the mechanisms linking delirium and dementia.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 123-139"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How should Null Findings be Interpreted?","authors":"Jeannie-Marie Leoutsakos Ph.D.","doi":"10.1016/j.jagp.2024.08.006","DOIUrl":"10.1016/j.jagp.2024.08.006","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 219-221"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the Last Leg of the Sail","authors":"George S. Alexopoulos M.D.","doi":"10.1016/j.jagp.2024.11.004","DOIUrl":"10.1016/j.jagp.2024.11.004","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 225-227"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: “How should Null Findings be Interpreted?”","authors":"Charles South Ph.D. ,&nbsp;Stephan Arndt Ph.D.","doi":"10.1016/j.jagp.2024.09.004","DOIUrl":"10.1016/j.jagp.2024.09.004","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 222-223"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delirium and dementia: Two of a kind?","authors":"Aartjan TF Beekman M.D., Ph.D.","doi":"10.1016/j.jagp.2024.08.007","DOIUrl":"10.1016/j.jagp.2024.08.007","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 140-142"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Cognitive Frailty With Subsequent All-Cause Mortality Among Middle-Aged and Older Adults in 17 Countries","authors":"Yemin Yuan Ph.D. ,&nbsp;Huaxin Si Ph.D. ,&nbsp;Zhenyu Shi Ph.D. ,&nbsp;Yanshang Wang Ph.D. ,&nbsp;Yiqi Xia Ph.D. ,&nbsp;Xiaolong Guan Ph.D. ,&nbsp;Ping He Ph.D.","doi":"10.1016/j.jagp.2024.08.009","DOIUrl":"10.1016/j.jagp.2024.08.009","url":null,"abstract":"<div><h3>Objectives</h3><div>Cognitive frailty refers to the co-occurrence of cognitive impairment and frailty without concurrent Alzheimer's disease or dementia. Studies of cognitive frailty and mortality have been limited to single country or older people. However, frailty and cognitive decline may occur much earlier. We aimed to examine the association between different cognitive frailty status and subsequent all-cause mortality among middle-aged and older people in 17 countries.</div></div><div><h3>Methods</h3><div>Participants aged 50 and over were drawn from six prospective cohorts of aging. We classified participants according to their cognitive impairment and frailty status into the following groups: none, only cognitive impairment, only frailty and cognitive frailty. Competing-risks regression models were used to evaluate the association of different cognitive frailty status at baseline with subsequent all-cause mortality.</div></div><div><h3>Results</h3><div>The cognitive frailty group had a higher mortality risk compared to those without cognitive impairment and frailty groups. Meta-analysis results showed participants with cognitive frailty (pooled subhazard ratio [SHR] = 2.34, 95% confidence interval [CI]: 2.01–2.72, I² = 68.0%) had a higher mortality risk compared with those with only cognitive impairment status (pooled SHR = 1.36, 95% CI: 1.25–1.48, I² = 3.0%) or only frailty status (pooled SHR = 1.83, 95% CI: 1.72–1.95, I² = 31.0%). The association between cognitive frailty and mortality were stronger among those who were aged 70 years and older, males, single and nonconsumers of alcohol.</div></div><div><h3>Conclusions</h3><div>Cognitive frailty, frailty or cognitive impairment alone, is associated with an increased risk of all-cause mortality in Asian, European and American countries. Physical and cognitive function screening should be conducted as early as possible in middle-aged and older people, and targeted intervention approaches should be developed to reduce the incidence of adverse health outcomes.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 178-191"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Responding to the Growing Need for Medical Experts in Testamentary and Estate Related Capacities: A Course for Physicians","authors":"J. Kirkham M.D., M.Sc. ,&nbsp;S.B. Mitchell M.D., MPH ,&nbsp;C. Cohen M.D. ,&nbsp;C. Hao M.Sc. ,&nbsp;K. Shulman M.D., S.M.","doi":"10.1016/j.jagp.2024.08.013","DOIUrl":"10.1016/j.jagp.2024.08.013","url":null,"abstract":"<div><h3>Objectives</h3><div>The objective of this continuing medical education course was to improve the knowledge and skills of physicians in the assessment of testamentary and related capacities.</div></div><div><h3>Methods</h3><div>We developed, conducted, and evaluated an accredited medical education course focusing on the role and responsibilities of medical experts in estate litigation and held in Toronto, Ontario, Canada in June 2022.</div></div><div><h3>Results</h3><div>Participants reported a 65% and 35% improvement in confidence in conducting retrospective and contemporaneous assessments of testamentary capacity, respectively. The overall mean score in the 9 key competencies for medical experts in estate litigation improved by 1.2-points from 3.02 (SD 1.33) to 4.22 (SD 0.74) from pre to postcourse (p &lt;0.05, 95% CI [−1.66, −0.67]).</div></div><div><h3>Conclusions</h3><div>This course addresses a significant gap in training and formal education opportunities in testamentary and other related capacities that may contribute to increasing the pool of available and qualified medical experts in estate litigation.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 169-175"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forever The Wind","authors":"Mark Steven Aster","doi":"10.1016/j.jagp.2024.11.005","DOIUrl":"10.1016/j.jagp.2024.11.005","url":null,"abstract":"","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Page 228"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discontinuing the Term “Stakeholder” From the NIA IMPACT Collaboratory Engaging Partners Team: An Example of the Process of Language Change in an Organization","authors":"Evan Plys Ph.D. ,&nbsp;Karen O. Moss Ph.D. ,&nbsp;Kristen Jacklin Ph.D. ,&nbsp;Molita Yazzie M.S. ,&nbsp;Ellen Tambor M.A. ,&nbsp;Erin Luers M.S. ,&nbsp;Linda Elam Ph.D. ,&nbsp;Nina Ahmad B.S. ,&nbsp;Zachary J. Kunicki Ph.D. ,&nbsp;Carolyn Malone M.P.H. ,&nbsp;Gary Epstein-Lubow M.D.","doi":"10.1016/j.jagp.2024.08.016","DOIUrl":"10.1016/j.jagp.2024.08.016","url":null,"abstract":"<div><div>In this paper, we describe our process of changing language of the National Institute on Aging Imbedded Pragmatic Alzheimer's disease and AD-related dementias Clinical Trials Collaboratory (NIA IMPACT Collaboratory) “Stakeholder Engagement Team” to “Engaging Partners Team” in response to feedback from community partners regarding the problematic connotations of the term “stakeholder.” We present a brief history of the term “stakeholder” and its use in clinical and community-engaged research. Then, we summarize critiques of this term, including its colonial history and potential to reinforce complacency with generational traumas, particularly among Indigenous peoples and communities. We conclude with a detailed overview of our team and organization's multi-step process to discontinue use of the term “stakeholder,” in alignment with a theoretical model of organizational behavior change. This paper highlights the importance of critically evaluating language and responding to community partners. We hope our process can guide other researchers and organizations.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 192-199"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life Fatigue: A Critical Analysis","authors":"Margarita Bofarull MD, MA ,&nbsp;Montse Esquerda MD, PhD ,&nbsp;David Lorenzo PhD ,&nbsp;Francesc Torralba PhD ,&nbsp;Victoria Cusi PhD ,&nbsp;José Antonio Suffo PhD ,&nbsp;Juan Maria Velasco PhD ,&nbsp;Jacinto Bátiz MD, PhD ,&nbsp;Miguel Martin MA ,&nbsp;Javier de la Torre PhD ,&nbsp;Francisco José Cambra MD, PhD ,&nbsp;Joan Bertran MD, PhD","doi":"10.1016/j.jagp.2024.08.002","DOIUrl":"10.1016/j.jagp.2024.08.002","url":null,"abstract":"<div><h3>Introduction</h3><div>In recent years, euthanasia has been decriminalized or legalized in several countries. The debate on whether to legalize such a practice is open in many places and is a topic that arouses great controversy. Euthanasia has been presented as a response to situations of advanced, incurable, or irreversible disease, or situations that cause intolerable suffering to the person. However, in recent years, the claim has been asserted that this practice does not have to be associated with such situations. It may happen that a person wants to die and asks for help to do so, even if they are not in a specific clinical situation (pathology or condition) but are experiencing advanced age or present ‘vital fatigue’.</div></div><div><h3>Aim</h3><div>The objective of this article is to critically analyse the concept ‘vital fatigue’: define its meaning, its characteristics, its causes, and its consequences in the debate around euthanasia. To do this, a critical review of the main discussions and arguments present in the literature is made.</div></div><div><h3>Conclusions</h3><div>It is concluded that vital fatigue can be understood as a product or manifestation of an individualistic and productivistic vision of the human being, in which its relational nature and intrinsic value remain in the background. The loss of the meaning of life also influences him. Therefore, in the face of this phenomenon, the most guaranteeing and ethical option is –we believe–accompaniment and holistic care of the person that allows the causal factors to be modulated, without the need to resort to euthanasia.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":"33 2","pages":"Pages 200-208"},"PeriodicalIF":4.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}