American Journal of Geriatric Psychiatry最新文献_第6页

Caregiver Contributions to Older Veterans’ Mental Health Utilization: New Opportunities for Exploring Caregiving Roles and Impacts 护理人员对老年退伍军人利用心理健康的贡献：探索护理角色和影响的新机遇

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-25 DOI: 10.1016/j.jagp.2024.07.010

引用次数: 0

Living Alone With Dementia: A Reality Check 痴呆症患者独自生活：现实检验

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-25 DOI: 10.1016/j.jagp.2024.07.006

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Catatonia in Dementia: A Systematic Review of Case Reports and Case Series 痴呆症中的紧张症：病例报告和系列病例的系统回顾

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-22 DOI: 10.1016/j.jagp.2024.07.012

{"title":"Catatonia in Dementia: A Systematic Review of Case Reports and Case Series","authors":"","doi":"10.1016/j.jagp.2024.07.012","DOIUrl":"10.1016/j.jagp.2024.07.012","url":null,"abstract":"<div><h3>Background</h3><div>Catatonia is a neuropsychiatric syndrome characterized by motor, behavioral, and autonomic abnormalities. It is often underdiagnosed in geriatric patients with dementia despite established diagnostic criteria and treatment options.</div></div><div><h3>Objective</h3><div>This systematic review investigates catatonia in the elderly, particularly those with dementia, to examine their clinical presentation, treatment response, and prognosis compared to elderly patients without dementia.</div></div><div><h3>Methods</h3><div>We comprehensively searched MEDLINE and EMBASE, including case reports and series on catatonia in elderly patients. Reviewers independently performed data extraction and quality assessments. Statistical significance was set at a p value ≤0.05, and a multivariate logistic regression model was used to analyze differences between patients with and without dementia.</div></div><div><h3>Results</h3><div>Our review included 182 articles with 225 cases. We found no significant differences in the clinical presentation of catatonia between patients with and without dementia, with both groups commonly exhibiting the hypokinetic variant. However, patients with dementia were more frequently treated with NMDA receptor antagonists (OR: 3.27; CI: 1.05–10.11; p = 0.040) and had a lower complete response rate to treatment (OR: 0.37; CI: 0.19–0.75; p = 0.006). Patients with dementia also exhibited fewer acute medical conditions (OR: 0.17; CI: 0.05–0.65; p = 0.009).</div></div><div><h3>Conclusions</h3><div>Catatonia in dementia does not have a different syndromic presentation. However, the diagnosis of dementia leads to varying preferences regarding the choice of symptomatic therapy and seems to be a predictor of a poorer therapeutic response. Actively treating catatonia, particularly in patients with dementia, addressing the characteristics of these patients is of paramount importance.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on Neuropsychiatric Symptom Profile in Alzheimer's Disease and their Relationship with Functional Decline 关于阿尔茨海默病的神经精神症状及其与功能衰退的关系的评论。

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-16 DOI: 10.1016/j.jagp.2024.07.007

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Efficacy of Nonpharmacological Interventions in Cognitive Impairment: Systematic Review And Network Meta-Analysis 非药物干预对认知障碍的疗效：系统综述和网络荟萃分析

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-09 DOI: 10.1016/j.jagp.2024.06.012

{"title":"Efficacy of Nonpharmacological Interventions in Cognitive Impairment: Systematic Review And Network Meta-Analysis","authors":"","doi":"10.1016/j.jagp.2024.06.012","DOIUrl":"10.1016/j.jagp.2024.06.012","url":null,"abstract":"<div><h3>Introduction</h3><div>There is currently no known cure for cognitive impairment, which highlights the need to explore other ways of managing this condition. This topic has recently become an area of active research. However, the availability of nonpharmacological options poses a challenge when trying to determine the best treatment for improving cognitive function.</div></div><div><h3>Methods</h3><div>We conducted a systematic review and a Bayesian network meta-analysis to compare the effects of nonpharmacological interventions on global cognition in patients with mild cognitive impairment and dementia. The nonpharmacological interventions were classified as aerobic exercise, strength exercise, multicomponent physical exercise, other physical exercises, tai chi, mind-body exercises, traditional cognitive rehabilitation, computer-based cognitive rehabilitation, occupational therapy, music therapy, physical-cognitive rehabilitation, and reminiscence therapy.</div></div><div><h3>Results</h3><div>Physical-cognitive rehabilitation emerged as the most effective nonpharmacological intervention for enhancing global cognition in patients with unspecified cognitive impairment and dementia, whereas occupational therapy focused on dual-task interventions was found to be the most effective nonpharmacological intervention for mild cognitive impairment.</div></div><div><h3>Conclusion</h3><div>These results underscore the importance of adopting a dual approach to managing cognitive impairment, integrating both cognitive and physical rehabilitation within the same intervention.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Explanatory Note - CiteScore Versus Impact Factor 解释性说明--CiteScore 与影响因子的比较

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-04 DOI: 10.1016/j.jagp.2024.07.001

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Beta-to-Theta Entropy Ratio of EEG in Aging, Frontotemporal Dementia, and Alzheimer's Dementia 衰老、额颞叶痴呆和阿尔茨海默氏症患者脑电图的 Beta 与 Theta 熵比。

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-04 DOI: 10.1016/j.jagp.2024.06.009

{"title":"Beta-to-Theta Entropy Ratio of EEG in Aging, Frontotemporal Dementia, and Alzheimer's Dementia","authors":"","doi":"10.1016/j.jagp.2024.06.009","DOIUrl":"10.1016/j.jagp.2024.06.009","url":null,"abstract":"<div><h3>Background</h3><div>Aging, frontotemporal dementia<span> (FTD), and Alzheimer's dementia<span> (AD) manifest electroencephalography (EEG) alterations, particularly in the beta-to-theta power ratio derived from linear power spectral density (PSD). Given the brain's nonlinear nature, the EEG nonlinear features could provide valuable physiological indicators of aging and cognitive impairment. Multiscale dispersion entropy (MDE) serves as a sensitive nonlinear metric for assessing the information content in EEGs across biologically relevant time scales.</span></span></div></div><div><h3>Objective</h3><div>To compare the MDE-derived beta-to-theta entropy ratio with its PSD-based counterpart to detect differences between healthy young and elderly individuals and between different dementia subtypes.</div></div><div><h3>Methods</h3><div>Scalp EEG recordings were obtained from two datasets: 1) Aging dataset: 133 healthy young and 65 healthy older adult individuals; and 2) Dementia dataset: 29 age-matched healthy controls (HC), 23 FTD, and 36 AD participants. The beta-to-theta ratios based on MDE vs. PSD were analyzed for both datasets. Finally, the relationships between cognitive performance and the beta-to-theta ratios were explored in HC, FTD, and AD.</div></div><div><h3>Results</h3><div>In the Aging dataset, older adults had significantly higher beta-to-theta entropy ratios than young individuals. In the Dementia dataset, this ratio outperformed the beta-to-theta PSD approach in distinguishing between HC, FTD, and AD. The AD participants had a significantly lower beta-to-theta entropy ratio than FTD, especially in the temporal region, unlike its corresponding PSD-based ratio. The beta-to-theta entropy ratio correlated significantly with cognitive performance.</div></div><div><h3>Conclusion</h3><div>Our study introduces the beta-to-theta entropy ratio using nonlinear MDE for EEG analysis, highlighting its potential as a sensitive biomarker for aging and cognitive impairment.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Acting Injectable Antipsychotics in the Geriatric Population: A longitudinal Study 老年群体中的长效注射抗精神病药物：纵向研究

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-04 DOI: 10.1016/j.jagp.2024.06.007

{"title":"Long-Acting Injectable Antipsychotics in the Geriatric Population: A longitudinal Study","authors":"","doi":"10.1016/j.jagp.2024.06.007","DOIUrl":"10.1016/j.jagp.2024.06.007","url":null,"abstract":"<div><h3>Objective</h3><div>This study compares demographic, clinical characteristics, and outcomes in older adults on long-acting injectable antipsychotics (LAI-AP) vs. oral antipsychotics (PO-AP).</div></div><div><h3>Design</h3><div>This observational study with a retrospective cohort utilized the electronic medical record's search engine to review charts of geriatric patients on LAI-AP for a two-year period. A convenience sample on PO-AP formed the comparison group. LAI-AP patients were subcategorized into discontinuation and continuation groups.</div></div><div><h3>Setting</h3><div>Conducted at an urban, psychiatric outpatient clinic, using charts from October 2020 to 2022.</div></div><div><h3>Participants</h3><div>Patients at least 60 years-old with psychotic or mood disorders on antipsychotics for at least 3-months during the study period.</div></div><div><h3>Measurements</h3><div>Demographic and clinical variables, including diagnosis, medication type, side effects, medical comorbidities, neurocognitive status, and secondary medications, were collected for both PO-AP and LAI-AP groups. Outcome variables included missed appointments, psychiatric and medical hospitalizations, and emergency room visits. Correlates of discontinuation of LAI-AP were also assessed.</div></div><div><h3>Results</h3><div>LAI-AP had a higher proportion than PO-AP of primary psychotic disorders (87.8% vs. 64.3%). During the study, PO-AP had higher rates of missed appointments (median 18% vs. 13% for LAI-AP) and psychiatric admissions (mean 0.019/month vs. 0.006/month for LAI-AP;); Female sex was a risk factor for discontinuation of LAI-AP (86.7% of discontinuation group vs. 55.2% of continuation group).</div></div><div><h3>Conclusions</h3><div>The LAI-AP group showed reduced hospitalizations, better treatment engagement, and comparable tolerability to PO-AP. Preliminary data suggests gender may influence LAI-AP discontinuation rates. This study adds to the sparse literature investigating the efficacy and tolerability of LAI-AP in geriatric patients.</div></div>","PeriodicalId":55534,"journal":{"name":"American Journal of Geriatric Psychiatry","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Information for Subscribers 订户须知

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-04 DOI: 10.1016/S1064-7481(24)00366-X

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Response to the Editorial by Dr. Nelson and Dr. Delucchi 对纳尔逊博士和德卢奇博士社论的回应。

IF 4.4 2区医学

American Journal of Geriatric Psychiatry Pub Date : 2024-07-03 DOI: 10.1016/j.jagp.2024.06.008

引用次数: 0