Archives De Pediatrie最新文献

{"title":"Co-occurrence of esophageal atresia, duodenal atresia, and anorectal malformation: The DATE association","authors":"Silvia Ceccanti, Denis A. Cozzi","doi":"10.1016/j.arcped.2023.10.013","DOIUrl":"10.1016/j.arcped.2023.10.013","url":null,"abstract":"","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140133346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The pediatric intensive care unit in France: What happens afterwards?","authors":"Delphine Micaëlli ,&nbsp;Stéphane Dauger ,&nbsp;GFRUP – PICSp Study Group ,&nbsp;Albert Faye ,&nbsp;Michaël Levy","doi":"10.1016/j.arcped.2024.01.002","DOIUrl":"10.1016/j.arcped.2024.01.002","url":null,"abstract":"<div><p>Although pediatric post-intensive care syndrome is frequent and impacts the child's quality of life in various aspects, there are currently no guidelines regarding post-pediatric intensive care unit (PICU) follow-up. The aim of this study was to describe post-PICU follow-up in France. Among the 37 French PICUs, only 67 % had a consultation service, mostly performed by pediatric intensivists (95 %). Post-intensive care evaluation was the main objective for 46 % of these centers, whereas others focused on specific patient populations. Post-intensive care follow-up is highly heterogeneous and developing such consultation services appears to be a main challenge for PICU teams.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bordetella holmesii: Causative agent of pertussis","authors":"Meryem Elgarini ,&nbsp;Zakaria Mennane ,&nbsp;Mohammed Sobh ,&nbsp;Abdearrahmane Hammoumi","doi":"10.1016/j.arcped.2023.10.012","DOIUrl":"10.1016/j.arcped.2023.10.012","url":null,"abstract":"<div><p><em>Bordetella holmesii</em> is a bacterium recently recognized in 1995. It is a gram-negative coccobacillus that can cause pertussis-like symptoms in humans as well as invasive infections. It is often confused with <em>Bordetella pertussis</em> because routine diagnostic tests for whooping cough are not species-specific.</p><p>The prevalence of <em>B. holmesii</em> as a cause of pertussis has increased in several countries. Therefore, <em>B. holmesii</em> assays are important for determining the epidemiology of pertussis, for the choice of an effective treatment, and for detecting vaccination failures.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to ‘Management of obstructive sleep apnea syndrome type 1 in children and adolescents – A French consensus’ [Arch Pediatr (2023) 510–16]","authors":"G. Aubertin ,&nbsp;M. Akkari ,&nbsp;A. Andrieux ,&nbsp;C. Colas des Francs ,&nbsp;B. Fauroux ,&nbsp;P. Franco ,&nbsp;F. Gagnadoux ,&nbsp;O. Gallet de Santerre ,&nbsp;B. Grollemund ,&nbsp;S. Hartley ,&nbsp;D. Jaffuel ,&nbsp;L. Lafond ,&nbsp;C.M. Schröder ,&nbsp;C. Schweitzer ,&nbsp;C. Charley-Monaca","doi":"10.1016/j.arcped.2024.02.001","DOIUrl":"10.1016/j.arcped.2024.02.001","url":null,"abstract":"","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0929693X24000241/pdfft?md5=cce2ca4c3932d2011552a1c74a1bebb6&pid=1-s2.0-S0929693X24000241-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of lysozyme-induced anaphylaxis in a child with egg allergy","authors":"Charles Elbany ,&nbsp;Delphine de Boissieu ,&nbsp;Chantal Karila ,&nbsp;Marie-Alexandra Alyanakian ,&nbsp;Claude Ponvert ,&nbsp;Florence Lageix ,&nbsp;Guillaume Lezmi","doi":"10.1016/j.arcped.2023.12.005","DOIUrl":"10.1016/j.arcped.2023.12.005","url":null,"abstract":"<div><p>We report an unusual case of anaphylaxis induced by the lysozyme-containing over-the-counter-drug Lysopaine®, which contains 20 mg lysozyme hydrochloride and 1.5 mg cetylpyridinium chloride, in a 9-year-old child with allergy to hen's egg as well as multiple IgE-mediated food allergies. The involvement of lysozyme was confirmed by positive skin prick tests for Lysopaine® and the presence of specific IgE against lysozyme. Our case highlights the importance of properly educating allergic patients to recognize allergens, even minor ones. Despite the presence of lysozyme in various food and drug products, it is not necessarily perceived as an allergenic protein by patients with egg allergy, and the labeling may be misleading, thereby exposing patients to potentially severe reactions.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Airway obstruction in two children with congenital central hypoventilation syndrome and review of the literature","authors":"Richard Wolff ,&nbsp;Benjamin Dudoignon ,&nbsp;Jérôme Naudin ,&nbsp;Amélia Madani ,&nbsp;Christophe Delclaux ,&nbsp;Plamen Bokov ,&nbsp;Stéphane Dauger","doi":"10.1016/j.arcped.2023.12.002","DOIUrl":"10.1016/j.arcped.2023.12.002","url":null,"abstract":"<div><p>Congenital central hypoventilation syndrome (CCHS) is an autosomal dominant disease that is caused by heterozygous mutations in the paired-like homeobox 2B gene (<em>PHOX2B</em>). Madani et al. described an abnormally high degree of not only central apnea but also obstructive and mixed apnea in Phox2b^27Ala/+newborn mice. Newborns with CCHS must undergo polysomnography for obstructive respiratory events in order to guide the optimal ventilation strategy if oxygen desaturation, bradycardia, and malaise persist under noninvasive ventilation. Newborns and infants with CCHS must be systematically tested for obstructive apnea, especially in cases of inefficient noninvasive ventilation.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of vitamin D levels in children and adolescents after the first year of the COVID-19 pandemic: 1-year results of a secondary-level state hospital","authors":"Fatma Özgüç Çömlek ,&nbsp;Ali Toprak ,&nbsp;Ahmet Ziya Birbilen ,&nbsp;Semine Özdemir Dilek ,&nbsp;Fatma Coşkun","doi":"10.1016/j.arcped.2023.11.001","DOIUrl":"10.1016/j.arcped.2023.11.001","url":null,"abstract":"<div><h3>Background</h3><p>The COVID-19 pandemic caused a global public health problem with high morbidity and mortality rates. In this study, we aimed to evaluate the 25-hydroxyvitamin D (25(OH)D) status of patients presenting to the Pediatrics Department of Gaziantep Maternity and Children's Hospital in the 1-year period after the onset of the COVID-19 pandemic according to ethnicity, age, and gender.</p></div><div><h3>Method</h3><p>This cross-sectional study included the data of 7640 patients whose 25(OH)D levels were assessed at our hospital between March 2021 and March 2022. Vitamin D levels, age, gender, and the ethnic origin of the patients were retrospectively scanned and recorded from the laboratory results system. Based on the World Health Organization (WHO) classification of vitamin D levels, patients were divided into three groups: &lt;10 ng/mL = vitamin D deficiency; 10–19 ng/mL = vitamin D insufficiency, and 20 ng/mL and over = normal vitamin D status.</p></div><div><h3>Results</h3><p>The mean age of the 7640 patients who presented to the pediatrics department was 7.47 (±5.3) years. Of these patients, 48 % (3665) were male and 52 % (3975) were female. The mean vitamin D level of girls was 18.1 (±15.2) ng/mL, and of boys it was 20.2 (±15.4) ng/mL, with a statistically significant difference (<em>p</em> &lt; 0.001). In total, 21.2 % (1650) of patients had deficient, 43.3 % (3310) of patients had insufficient, and 35.5 % (2710) of patients had normal 25(OH)D levels. Overall, 21.8 % of the patients (1667) were immigrants, and in this group the deficiency was found to be statistically significantly higher at 27.4 % (<em>n</em> = 456; <em>p</em> &lt; 0.001). There was a low negative correlation between the age of the patients and their 25(OH)D levels (<em>r</em>=−0.35; <em>p</em> &lt; 0.001).</p></div><div><h3>Conclusions</h3><p>Vitamin D deficiency remains a serious public health problem. Since the most important production source is exposure to the sun, it must be kept in mind that vitamin D should be supported during lockdown pandemic processes.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for unexpected infant death among very premature infants in France","authors":"Anne-Laure Bourneuf ,&nbsp;Estelle Le Pabic ,&nbsp;Sophie de Visme ,&nbsp;Karine Levieux ,&nbsp;Patrick Pladys","doi":"10.1016/j.arcped.2023.12.003","DOIUrl":"10.1016/j.arcped.2023.12.003","url":null,"abstract":"<div><h3>Background</h3><p>Prematurity is one of the risk factors for sudden unexpected infant death (SUID), a phenomenon that remains poorly explained.</p></div><div><h3>Materials and methods</h3><p>The analysis of specific factors associated with SUID among very premature infants (VPI) was performed through a retrospective review of data collected in the French SUID registry from May 2015 to December 2018. The factors associated with SUID among VPI were compared with those observed among full-term infants (FTI). Results are expressed as means (standard deviation [SD]) or medians (interquartile range [IQR)].</p></div><div><h3>Results</h3><p>During the study period, 719 cases of SUID were included in the registry, 36 (incidence: 0.60 ‰) of which involved VPI (gestational age: 29.2 <span>[2]</span> weeks, 1157 [364]) g] and 313 (0.18 ‰) involved FTI (gestational age: 40 [0.8] weeks, 3298 [452] g). The infants’ postnatal age at the time of death was similar in the two groups: 15.5 (12.2–21.8) vs. 14.5 (7.1–23.4) weeks. We observed low breastfeeding rates and a high proportion of fathers with no occupation or unemployment status among the VPI compared to the FTI group (31% vs. 55 %, <em>p</em> = 0.01 and 32% vs. 13 %, <em>p</em> = 0.05, respectively). Among the VPI, only 52 % were in supine position, and 29 % were lying prone at the time of the SUID (compared to 63 % and 17 %, respectively, in the FTI group).</p></div><div><h3>Conclusion</h3><p>This study confirms prematurity as a risk factor for SUID with no difference in the SUID-specific risk factors studied except for breastfeeding and socioeconomic status of the fathers. VPI and FTI died at similar chronological ages with a high proportion of infants dying in prone position. These results argue for reinforcement of prevention strategies in cases of prematurity.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of pediatric heterozygous familial hypercholesterolemia 7 years after the EAS recommendations: Real-world results from a large French cohort","authors":"Noel Peretti ,&nbsp;Alexandre Vimont ,&nbsp;Emmanuel Mas ,&nbsp;Julie Lemale ,&nbsp;Rachel Reynaud ,&nbsp;Patrick Tounian ,&nbsp;Pierre Poinsot ,&nbsp;Liora Restier ,&nbsp;François Paillard ,&nbsp;Alain Pradignac ,&nbsp;Yann Pucheu ,&nbsp;Jean-Pierre Rabès ,&nbsp;Eric Bruckert ,&nbsp;Antonio Gallo ,&nbsp;Sophie Béliard","doi":"10.1016/j.arcped.2024.01.004","DOIUrl":"10.1016/j.arcped.2024.01.004","url":null,"abstract":"<div><h3>Background</h3><p>Heterozygous familial hypercholesterolemia (HeFH) predisposes to premature cardiovascular diseases. Since 2015, the European Atherosclerosis Society has advocated initiation of statins at 8–10 years of age and a low-density lipoprotein cholesterol (LDL-C) target of &lt;135 mg/dL. Longitudinal data from large databases on pharmacological management of pediatric HeFH are lacking.</p></div><div><h3>Objective</h3><p>Here, we describe treatment patterns and LDL-C goal attainment in pediatric HeFH using longitudinal real-world data.</p></div><div><h3>Methods</h3><p>This was a retrospective and prospective multicenter cohort study (2015–2021) of children with HeFH, diagnosed genetically or clinically, aged &lt;18 years, and followed up in the National French Registry of FH (REFERCHOL). Data on the study population as well as treatment patterns and outcomes are summarized as mean±SD.</p></div><div><h3>Results</h3><p>We analyzed the data of 674 HeFH children (age at last visit: 13.1 ± 3.6 years; 82.0 % ≥10 years; 52.5 % females) who were followed up for a mean of 2.8 ± 3.5 years. Initiation of lipid-lowering therapy was on average at 11.8 ± 3.0 years of age for a duration of 2.5 ± 2.8 years. At the last visit, among patients eligible for treatment (573), 36 % were not treated, 57.1 % received statins alone, 6.4 % statins with ezetimibe, and 0.2 % ezetimibe alone. LDL-C was 266±51 mg/dL before treatment and 147±54 mg/dL at the last visit (−44.7 %) in treated patients. Regarding statins, 3.3 %, 65.1 %, and 31.6 % of patients received high-, moderate-, and low-intensity statins, respectively. Overall, 59 % of children on statin therapy alone and 35.1 % on bitherapy did not achieve the LDL-C goal; fewer patients in the older age group did not reach the treatment goal.</p></div><div><h3>Conclusion</h3><p>Pediatric patients with FH followed up in specialist lipid clinics in France receive late treatment, undertreatment, or suboptimal treatment and half of them do not reach the therapeutic LDL-C goal. Finding a more efficient framework for linking scientific evidence to clinical practice is needed.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Necrotizing pneumonia in children: Report of 25 cases between 2008 and 2018 at a French tertiary care center","authors":"Manon Cathalau ,&nbsp;Marine Michelet ,&nbsp;Aurélien Rancé ,&nbsp;Guillaume Martin-Blondel ,&nbsp;Olivier Abbo ,&nbsp;Damien Dubois ,&nbsp;Géraldine Labouret ,&nbsp;Erick Grouteau ,&nbsp;Isabelle Claudet ,&nbsp;Lucas Ricco ,&nbsp;Léa Roditis ,&nbsp;Jean-Michel Mansuy ,&nbsp;Sophie Simon ,&nbsp;Camille Bréhin","doi":"10.1016/j.arcped.2023.12.004","DOIUrl":"10.1016/j.arcped.2023.12.004","url":null,"abstract":"<div><h3>Background</h3><p>Necrotizing pneumonia (NP) is a serious and rare disease in children. Pediatric data on NP are limited and the impact of the 13-valent pneumococcal conjugate vaccine has been very poorly evaluated.</p></div><div><h3>Patients and methods</h3><p>We conducted a retrospective study at Toulouse University Hospital between 2008 and 2018. Children who presented with thin-walled cavities in the areas of parenchymal consolidation on imaging were included in the study.</p></div><div><h3>Results</h3><p>The incidence of NP did not decrease during this period. Bacterial identification occurred in 56% of cases (14/25) and included six cases of <em>Streptococcus pneumoniae</em>, five of <em>Staphylococcus aureus</em>, two of <em>Streptococcus pyogenes</em>, and one of <em>Streptococcus viridans. Streptococcus pneumoniae</em> NP are more frequently associated with empyema/parapneumonic effusion compared to <em>S. aureus</em> NP (<em>p</em> = 0.02). Patients with <em>S. pyogenes</em> NP more often required volume expansion than did <em>S. pneumoniae</em> cases (<em>p</em> = 0.03). When comparing children born before and after implementation of the 13-valent pneumococcal conjugate vaccine, we identified a relative modification of the bacterial epidemiology, with an increase in the proportion of <em>S. pyogenes</em> NP and <em>S. aureus</em> NP and a decrease in the proportion of NP caused by <em>S. pneumoniae</em>.</p></div><div><h3>Conclusion</h3><p>Future studies are needed to assess the epidemiology of NP in children. Continued surveillance of identified pneumococcal serotypes is essential to document epidemiological changes in the coming years.</p></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140133348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}