{"title":"Should SGLT2 inhibitors be prescribed after myocardial infarction with left ventricular dysfunction?","authors":"Etienne Puymirat","doi":"10.1016/j.acvd.2024.10.002","DOIUrl":"10.1016/j.acvd.2024.10.002","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"117 11","pages":"Pages 613-615"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and clinical implications of a stepwise screening strategy for atrial fibrillation after stroke: Insights from the SAFAS study","authors":"Karim Benali , Gauthier Duloquin , Cyril Noto-Campanella , Lucie Garnier , Romain Didier , Thibaut Pommier , Gabriel Laurent , Catherine Vergely , Yannick Béjot , Charles Guenancia","doi":"10.1016/j.acvd.2024.07.062","DOIUrl":"10.1016/j.acvd.2024.07.062","url":null,"abstract":"<div><h3>Background</h3><div>Although guidelines recommend screening patients for atrial fibrillation (AF) after stroke, the optimal timing and combination of screening tools remain unclear.</div></div><div><h3>Aims</h3><div>We evaluated the suitability of a sequential combination of screening techniques for AF detected after stroke (AFDAS). We also compared patient characteristics according to the timing of AFDAS.</div></div><div><h3>Methods</h3><div>Patients without previous AF admitted for acute ischaemic stroke were prospectively enrolled. After a stepwise screening approach for AFDAS based on electrocardiogram, telemetry monitoring and in-hospital long-term Holter, patients with cryptogenic stroke underwent implantation of an implantable cardiac monitor (ICM). Early AFDAS was defined as AF diagnosed during hospitalization and late AFDAS as AF diagnosed on an ICM.</div></div><div><h3>Results</h3><div>Of the 240 patients included, 104 (43.3%) had a documented cause of stroke not related to AF. Among the 136 remaining patients, AFDAS was detected in 82 (60.3%) during the acute screening phase or during the 3-year follow-up by ICM. Early AFDAS was diagnosed by ECG, telemetry and in-hospital long-term Holter monitoring in 17 (20.7%), 25 (30.5%) and 18 (22.0%) patients, respectively. Among 76 patients who had an ICM implanted for cryptogenic stroke, AF was detected in 22 patients (28.9%). Except for age and stroke location, patients with early AFDAS did not differ from those with late AFDAS, particularly with regard to the prevalence of atrial cardiomyopathy markers.</div></div><div><h3>Conclusion</h3><div>A stepwise approach to AFDAS screening allows early detection of AF in a considerable number of patients during their hospitalization. ICMs remain complementary to non-invasive screening tools for the detection of remote episodes of AF.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"117 11","pages":"Pages 616-623"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pascal de Groote , Franck Thuny , Katrien Blanchart , Jean-Pierre Gueffet , Gilbert Habib , Muriel Salvat , Christophe Leclercq , Frederic Mouquet , Jérôme Roncalli , Laurent Sebbag , Romain Cassagneau , Michael Peyrol , Remi Sabatier , Carlo Gazzola , John Henderson , Philip B. Adamson , François Roubille
{"title":"Remote haemodynamic-guided heart failure management in France: Results from the CardioMEMS HF System Post-Market Study (COAST) French cohort","authors":"Pascal de Groote , Franck Thuny , Katrien Blanchart , Jean-Pierre Gueffet , Gilbert Habib , Muriel Salvat , Christophe Leclercq , Frederic Mouquet , Jérôme Roncalli , Laurent Sebbag , Romain Cassagneau , Michael Peyrol , Remi Sabatier , Carlo Gazzola , John Henderson , Philip B. Adamson , François Roubille","doi":"10.1016/j.acvd.2024.08.003","DOIUrl":"10.1016/j.acvd.2024.08.003","url":null,"abstract":"<div><h3>Background</h3><div>Previous studies have demonstrated the benefit of a haemodynamic-guided management strategy with the CardioMEMS™ HF System. No data from French patients have been published.</div></div><div><h3>Aims</h3><div>To analyse the feasibility, safety and clinical benefit of the CardioMEMS™ HF System in 103 French patients included in the CardioMEMS HF System Post-Market Study (COAST).</div></div><div><h3>Methods</h3><div>Prospective open-label cohort of New York Heart Association class III patients with at least one heart failure hospitalization in the 12 months before enrolment, regardless of left ventricular ejection fraction. The primary safety endpoints assessed the freedom from device/system-related complications and from pressure sensor failure at 2 years after implantation. The primary efficacy endpoint was evaluated comparing the rate of heart failure hospitalization during the year before and the year after implantation.</div></div><div><h3>Results</h3><div>At 2 years, there were no device/system-related complications or pressure sensor failures (<em>P</em> <!--><<!--> <!-->0.0001). There were 179 heart failure hospitalizations in the year before implantation compared with 79 in the year after implantation (risk reduction 50.3%; rate ratio 0.50, 95% confidence interval 0.38–0.66; <em>P</em> <!--><<!--> <!-->0.0001). During the 2 years of follow-up, pulmonary artery pressures were lowered significantly (mean pulmonary artery pressure –3.7<!--> <!-->±<!--> <!-->6.3<!--> <!-->mmHg; <em>P</em> <!--><<!--> <!-->0.0001), with a significant improvement in functional class and quality of life.</div></div><div><h3>Conclusions</h3><div>In the French cohort of the COAST study, we have demonstrated that the CardioMEMS™ HF System is a reliable device, with no device/system-related complications or pressure sensor failures. Patients in this open-label cohort had a significant reduction in pulmonary artery pressures, with an improvement in New York Heart Association classification and quality of life, and a 50% reduction in the heart failure hospitalization rate in the year following implantation compared with the previous year.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"117 11","pages":"Pages 624-632"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pierre-Léo Laporte, Martino Vaglio, Isabelle Denjoy, Pierre Maison-Blanche, Charlène Coquard, Nathan El Bèze, Philippe Maury, Alexis Hermida, Didier Klug, Alice Maltret, Fabio Badilini, Antoine Leenhardt, Fabrice Extramiana
{"title":"Automatized quantitative electrocardiography from digitized paper electrocardiograms: A new avenue for risk stratification in patients with Brugada syndrome.","authors":"Pierre-Léo Laporte, Martino Vaglio, Isabelle Denjoy, Pierre Maison-Blanche, Charlène Coquard, Nathan El Bèze, Philippe Maury, Alexis Hermida, Didier Klug, Alice Maltret, Fabio Badilini, Antoine Leenhardt, Fabrice Extramiana","doi":"10.1016/j.acvd.2024.05.123","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.05.123","url":null,"abstract":"<p><strong>Background: </strong>Arrhythmic risk stratification is a major challenge in Brugada syndrome. Studies have evaluated risk stratification based on manually measured electrocardiogram (ECG) parameters at baseline and/or after drug challenge.</p><p><strong>Aim: </strong>To assess the predictive value of multiple ECG parameters measured automatically from digitized paper ECGs.</p><p><strong>Methods: </strong>During a prospective, multicentre cohort study that included patients with Brugada syndrome with type 1 ECG (spontaneously or drug-induced), paper ECGs were digitized and analysed. Major events were sudden cardiac death, aborted cardiac arrest and appropriate implantable cardioverter-defibrillator (ICD) therapy in the ventricular fibrillation (VF) zone. The predictive value of clinical and ECG parameters was assessed using univariable and multivariable Cox models.</p><p><strong>Results: </strong>ECGs from 301 patients (74% male, mean age 43.1±13.3years, mean follow-up 7.1±5.6years) were analysed. Major events occurred in 6% of patients before diagnosis and 8% during follow-up. Two baseline ECG parameters were independently associated with major events: QRS prolongation in lead V1>113ms (hazard ratio [HR] 3.49, 95% confidence interval [CI] 1.72-7.09; P<0.001) and S duration on DI>33.5ms (HR 3.56, 95% CI 1.52-8.31; P<0.01). In drug-induced patients, changes in the Tpeak-Tend interval on V2 were associated with major events (HR 4.69, 95% CI 1.21-18.17; P=0.014).</p><p><strong>Conclusion: </strong>Paper ECG datasets could be used for automatic quantitative ECG measurements. We confirmed the association of previously described parameters with events and identified useful new parameters. Multi-parametric ECG quantification may be used to assess risk in patients with Brugada syndrome.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiac magnetic resonance imaging-derived right ventricular volume and function, and association with outcomes in isolated tricuspid regurgitation.","authors":"Gaspard Suc, Thibault Dewavrin, Jules Mesnier, Eric Brochet, Kankoe Sallah, Axelle Dupont, Phalla Ou, Marylou Para, Dimitri Arangalage, Marina Urena, Bernard Iung","doi":"10.1016/j.acvd.2024.09.006","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.09.006","url":null,"abstract":"<p><strong>Background: </strong>In patients with significant tricuspid regurgitation, cardiac magnetic resonance imaging (CMR) is the preferred method for the evaluation of right ventricular function and volumes. However validated thresholds are lacking.</p><p><strong>Aim: </strong>The aim of this study was to evaluate CMR assessment of right ventricular volumes in patients with significant (moderate or severe) tricuspid regurgitation, and to define its association with outcomes.</p><p><strong>Methods: </strong>The PRONOVAL study is a retrospective multicentre study using the clinical data warehouse of Greater Paris University Hospitals (AP-HP). Patients were screened for CMR in the PMSI (Programme de médicalisation des systèmes d'information). Hospitalization reports were analysed by natural language processing to include patients with tricuspid regurgitation. Exclusion criteria were left heart valvular disease, heart transplantation and cardiac amyloidosis. Primary outcome was a combined criterion of death or tricuspid surgery.</p><p><strong>Results: </strong>Between September 2017 and September 2021, 151 patients with isolated tricuspid regurgitation were screened. Right ventricular function and volumes were available in 86 (57.0%) CMR reports (the complete CMR group). In the complete CMR group, tricuspid regurgitation was severe in 62 patients (72.1%). Median age was 67.0 years (interquartile range 58.0-75.8). Median right ventricular indexed end-diastolic volume was 98.0 mL/m<sup>2</sup> (interquartile range 66.8-118.5). At 2-year follow-up, six patients (9.2%) had undergone tricuspid valve surgery, and 12 patients (18.5%) had died. Right ventricular indexed end-diastolic volume was associated with death or surgery at 2years, with an area under the receiver operating characteristic curve of 0.76 (95% confidence interval 0.75-0.77) for a threshold of 119mL/m<sup>2</sup>.</p><p><strong>Conclusion: </strong>Right ventricular indexed end-diastolic volume >119mL/m<sup>2</sup> was found to be an independent indicator of death or surgery in patients with significant tricuspid regurgitation.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to a letter from Modumudi et al. commenting on the article \"Cardiogenic shock and infection: A lethal combination\".","authors":"Miloud Cherbi, Hamid Merdji, Clément Delmas","doi":"10.1016/j.acvd.2024.09.005","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.09.005","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Peschanski, Florian Zores, Jacques Boddaert, Bénedicte Douay, Clément Delmas, Amaury Broussier, Delphine Douillet, Emmanuelle Berthelot, Thomas Gilbert, Cédric Gil-Jardiné, Vincent Auffret, Laure Joly, Jérémy Guénézan, Michel Galinier, Marion Pépin, Pierrick Le Borgne, Philippe Le Conte, Nicolas Girerd, Frédéric Roca, Mathieu Oberlin, Patrick Jourdain, Geoffroy Rousseau, Nicolas Lamblin, Barbara Villoing, Frédéric Mouquet, Xavier Dubucs, François Roubille, Maxime Jonchier, Rémi Sabatier, Saïd Laribi, Muriel Salvat, Tahar Chouihed, Jean-Baptiste Bouillon-Minois, Anthony Chauvin
{"title":"2023 SFMU/GICC-SFC/SFGG expert recommendations for the emergency management of older patients with acute heart failure. Part 2: Therapeutics, pathway of care and ethics.","authors":"Nicolas Peschanski, Florian Zores, Jacques Boddaert, Bénedicte Douay, Clément Delmas, Amaury Broussier, Delphine Douillet, Emmanuelle Berthelot, Thomas Gilbert, Cédric Gil-Jardiné, Vincent Auffret, Laure Joly, Jérémy Guénézan, Michel Galinier, Marion Pépin, Pierrick Le Borgne, Philippe Le Conte, Nicolas Girerd, Frédéric Roca, Mathieu Oberlin, Patrick Jourdain, Geoffroy Rousseau, Nicolas Lamblin, Barbara Villoing, Frédéric Mouquet, Xavier Dubucs, François Roubille, Maxime Jonchier, Rémi Sabatier, Saïd Laribi, Muriel Salvat, Tahar Chouihed, Jean-Baptiste Bouillon-Minois, Anthony Chauvin","doi":"10.1016/j.acvd.2024.09.004","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.09.004","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sravani Modumudi, Vanessa Rodriguez, Laura Calderon Suarez
{"title":"Letter commenting on the article entitled \"Cardiogenic shock and infection: A lethal combination\" by Cherbi et al.","authors":"Sravani Modumudi, Vanessa Rodriguez, Laura Calderon Suarez","doi":"10.1016/j.acvd.2024.08.010","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.08.010","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}