Archives of Cardiovascular Diseases最新文献

{"title":"Rheumatic lesions of the pulmonary valve: A systematic review of the literature.","authors":"Martin Wendlassida Nacanabo, Anna Tall-Thiam, André Arthur Taryètba Seghda, Ella Hatoula Lengani, Prisca Lamoudi Thiombiano, Claudine Djième Dah, Mureille Loya-Abouga, Aimé Arsène Yaméogo, Adolphe Benjamin Ouattara-Zingé, Georges Christian Rosario Millogo, Jonas Koudougou Kologo, Yibar Kambiré, Valentin Nobila Yaméogo, André Koudnoaga Samadoulougou, Patrice Zabsonré","doi":"10.1016/j.acvd.2026.07.010","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.07.010","url":null,"abstract":"<p><strong>Background: </strong>Rheumatic pulmonary valve disease accounts for<1% of cases of rheumatic heart disease. Because of its rarity, this valvular disease is often overlooked and underdiagnosed.</p><p><strong>Aim: </strong>To conduct a systematic review of reported cases of rheumatic pulmonary valve disease worldwide.</p><p><strong>Methods: </strong>Studies reporting confirmed cases of rheumatic pulmonary valve disease, and providing sufficient clinical, diagnostic, therapeutic or follow-up data were included. Duplicate checking, selection, data extraction and quality assessment of the included studies were carried out by two reviewers, independently. The Joanna Briggs Institute critical appraisal tools were used for quality assessment. The process did not result in a meta-analysis because of significant heterogeneity and a lack of data. The review protocol is registered on the Prospective Registry of Systematic Reviews (CRD420261341732).</p><p><strong>Results: </strong>We identified 909 publications across the six databases. Following deduplication and selection, we included a total of 30 studies involving 35 patients, published between 1931 and 2025. Case reports predominated, accounting for 87% of studies (n=26); case series accounted for 13% (n=4). Age ranged from 3 to 83 years (median 29 years). There was a female predominance (n=20; 57%). India accounted for 37% of cases (n=13), followed by the USA with 11% (n=4). Only 46% of patients (n=16) presented with acute rheumatic fever or pre-existing rheumatic heart disease on admission. Dyspnoea was a constant symptom in all patients. Seven patients (20%) presented with atrial fibrillation. A procedure was performed in 74% of cases (n=26): pulmonary valve replacement in 40% (n=14); balloon dilation in 11% (n=4); and intraoperative commissurotomy in 20% (n=7). The clinical outcome was favourable in 74% of the documented cases (n=26).</p><p><strong>Conclusions: </strong>Rheumatic pulmonary valve disease is a rare condition, but is likely to be underdiagnosed and underreported; it most commonly forms part of a quadrivalent valve disease. This review highlights the need for increased clinical and paraclinical vigilance when assessing the pulmonary valve in rheumatic heart disease.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and determinants of non-radial vascular approach for coronary angiography in heart transplant recipients.","authors":"Niki Procopi, Paul Guedeney, Arnaud Ferrante, Michel Zeitouni, Mathieu Kerneis, Olivier Barthelemy, Claude Le Feuvre, Johanne Silvain, Emmanuel Berman, Ghilas Rahoual, Victorien Monguillon, David Sulman, Marie Dupuy, Louis Giovachini, Pierre Charleux, Guillaume Coutance, Shaida Varnous, Pascal Leprince, Guillaume Lebreton, Gilles Montalescot, Gérard Helft","doi":"10.1016/j.acvd.2026.07.009","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.07.009","url":null,"abstract":"<p><strong>Background: </strong>Heart transplantation (HT) recipients undergo repeated coronary angiographies to screen for coronary allograft vasculopathy, which increases exposure to non-radial vascular access and potential related complications.</p><p><strong>Aims: </strong>To describe the incidence and determinants of non-radial vascular approach among HT recipients in a large HT centre.</p><p><strong>Methods: </strong>Consecutive HT recipients undergoing coronary angiography between October 2020 and March 2024 in the largest European HT centre were included, and all their previous coronary angiographies performed after HT were retrospectively reviewed. Determinants of non-radial vascular approach were assessed using multivariable logistic regression analyses, which included the individual mean number of coronary angiographies per year after HT to account for disparities in follow-up.</p><p><strong>Results: </strong>A total of 429 patients (21.4% female, median [interquartile range] age at HT 50 [38-58] years) underwent a total of 1927 procedures, with a median number of 3 (1-7) coronary angiographies per patient performed over a median duration of 6.7 (1.3-12.9) years. The cumulative rate of non-radial vascular approach at 10 years was 35.5% (95% confidence interval: 29.9-41.1%). Independent determinants of non-radial vascular approach were HT for ischaemic heart disease (adjusted odds ratio [aOR]: 2.78, 95% confidence interval [95% CI]: 1.69-4.54), multiple HT (aOR: 5.71, 95% CI: 1.42-23.01), female sex (aOR: 2.22, 95% CI: 1.18-4.16) and chronic dialysis after HT (aOR: 3.19, 95% CI: 1.09-9.28), but the number of procedures was not. Severe vascular complications were rare and not significantly different between vascular accesses.</p><p><strong>Conclusions: </strong>In this high-volume centre, non-radial vascular approach was used in approximately one third of HT recipients during their follow-up, with multiple reasons, albeit not including the overall number of procedures performed.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter in response to the article entitled \"Predictive score for supraventricular arrhythmia after patent foramen ovale percutaneous closure\" by Giovachini et al.","authors":"Ezgi Gültekin Güner, Kaan Gökçe, Ahmet Güner","doi":"10.1016/j.acvd.2026.09.002","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.09.002","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149118719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to letter by Güner et al. regarding \"Predictive score for supraventricular arrhythmia after patent foramen ovale percutaneous closure\".","authors":"Louis Giovachini, Paul Guedeney, Gilles Montalescot","doi":"10.1016/j.acvd.2026.09.001","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.09.001","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149118899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thromboprophylaxis in congenital and acquired heart disease across the lifespan. A French consensus position statement: Part 2 - from adolescence to adulthood.","authors":"Clement Karsenty, Magalie Ladouceur, Neil Derridj, Olivia Domanski, Estiballiz Valdeolmillos, Pamela Moceri, Dominique Lasne, Nicolas Combes, Ramona Ghenghea, Laurence Iserin, Francis Bessiere, Lea Linglart, Damien Bonnet, Sebastien Hascoet, Sophie Malekzadeh-Milani, Fanny Bajolle","doi":"10.1016/j.acvd.2026.07.006","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.07.006","url":null,"abstract":"<p><p>Patients with congenital and acquired heart disease are exposed to a lifelong thromboembolic risk that increases progressively from adolescence to adulthood because of residual lesions, arrhythmias, venous congestion, repeated interventions and acquired co-morbidities. Management is further complicated by concurrent bleeding risk. To provide practical expert consensus recommendations on thromboprophylaxis in congenital and acquired heart disease from adolescence to adulthood. A multidisciplinary expert panel from the Paediatric and Congenital Cardiology Branch of the French Society of Cardiology conducted a focused literature review and structured consensus process. Recommendations were graded pragmatically according to available evidence and expert agreement. Major clinical scenarios include Fontan circulation, Eisenmenger syndrome and Kawasaki coronary sequelae. From adolescence, bleeding risk may increase in girls and women as a result of dysovulation, menstruation and anticoagulant-related uterine bleeding, warranting gynaecological referral. In adulthood, thrombotic burden progressively increases through cumulative exposure to arrhythmias and reinterventions, such as transcatheter pulmonary valve replacement. Management should therefore rely on individualized treatment integrating thrombosis-bleeding balance, serial reassessment, patient education and tailored choice among antiplatelet therapy, vitamin K antagonists and direct oral anticoagulants. Thromboprophylaxis from adolescence to adulthood should move towards lifelong personalized care based on cumulative risk exposure, changing clinical status and sex-specific issues. Large prospective studies are required to refine risk stratification and optimize treatment pathways.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clozapine-associated cardiotoxicity: Risk factors and long-term cardiovascular outcomes from a multicentre propensity-matched analysis.","authors":"Eric Yalley, Beloved Adenuga, Ayomide Ogunsakin, Raenique Doran, Miriam Michael","doi":"10.1016/j.acvd.2026.07.004","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.07.004","url":null,"abstract":"<p><strong>Background: </strong>Clozapine-associated cardiotoxicity, including myocarditis, is a recognized early complication. Risk factors and long-term cardiovascular consequences remain poorly defined.</p><p><strong>Aim: </strong>To evaluate heart failure, arrhythmia, cardiomyopathy and mortality outcomes among clozapine-treated patients with and without cardiotoxicity.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using the TriNetX Global Collaborative Network. Adults exposed to clozapine were identified. Adults initiating clozapine were identified and classified by early cardiotoxicity, defined as elevated troponin within 6 weeks and 90 days of initiation. Propensity score matching (1:1) was performed to balance baseline demographics and co-morbidities. Outcomes were assessed over 5 years from index. Cox proportional hazards models were used to identify predictors of early cardiotoxicity. Hazard ratios (HRs) with 95% confidence intervals (CIs) were reported.</p><p><strong>Results: </strong>After matching, 1203 patients were included in each cohort within the 6-week exposure window. Over 5 years of follow-up, heart failure occurred in 4.7% of patients with early cardiotoxicity compared with 3.8% of those without (HR: 1.76, 95% CI: 1.16-2.68). Arrhythmias occurred in 6.9% vs. 6.2% (HR: 1.54, 95% CI: 1.09-2.18), and cardiomyopathy in 1.9% vs. 1.0% (HR: 2.59, 95% CI: 1.27-5.29). All-cause mortality did not differ significantly between groups (9.9% vs. 10.4%; HR: 1.25, 95% CI: 0.96-1.62). In a secondary analysis using a 90-day exposure window, findings were consistent for cardiovascular outcomes, whereas all-cause mortality was modestly increased (HR: 1.36, 95% CI: 1.06-1.76). Cox regression identified male sex, younger age, obesity, valproate coadministration and concomitant antipsychotic use (risperidone, olanzapine, quetiapine) as independent risk factors, whereas traditional cardiovascular co-morbidities were not significantly associated with outcomes.</p><p><strong>Conclusions: </strong>Early clozapine cardiotoxicity predicts long-term heart failure, arrhythmias and cardiomyopathy, but not mortality. Risk is higher in males, younger patients, those with obesity and those taking valproate or multiple antipsychotics. Findings support early risk stratification and ongoing cardiovascular surveillance.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thromboprophylaxis in congenital and acquired heart disease across the lifespan. A French consensus position statement: Part 1 - from infancy to adolescence.","authors":"Neil Derridj, Lea Linglart, Dominique Lasne, Bruno Lefort, Daniela Laux, Sylvie Di Filippo, Cristian Mirabile, Nicolas Combes, Caroline Ovaert, Damien Bonnet, Ramona Ghenghea, Sebastien Hascoet, Fanny Bajolle, Clement Karsenty","doi":"10.1016/j.acvd.2026.07.005","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.07.005","url":null,"abstract":"<p><strong>Background: </strong>Thromboembolic complications are an important source of morbidity in children with congenital and acquired heart disease. Management is challenging because haemostasis characteristics evolve with age, evidence is limited and clinical scenarios are heterogeneous.</p><p><strong>Aim: </strong>To provide practical expert consensus recommendations on thromboprophylaxis in congenital and acquired heart disease from infancy to adolescence.</p><p><strong>Methods: </strong>A multidisciplinary expert panel from the Paediatric and Congenital Cardiology Branch of the French Society of Cardiology conducted a focused literature review and structured consensus process. Recommendations were graded pragmatically according to available evidence and expert agreement.</p><p><strong>Results: </strong>During infancy and childhood, thrombosis risk is increased in selected conditions, such as Kawasaki disease, paediatric cardiomyopathy and procedural neonatal exposure. During adolescence, bleeding risk may rise, particularly in girls, because of dysovulation and abnormal uterine bleeding during antithrombotic therapy. Across all stages, management should rely on individualized treatment, integrating thrombosis-bleeding balance, serial assessment, patient education and selection between antiplatelet therapy, vitamin K antagonists and direct oral anticoagulants according to indication and age. Aspirin therapy remains the first choice in several indications, whereas anticoagulation is required in selected high-risk conditions. Direct oral anticoagulants are emerging as promising alternatives in older children, although paediatric-specific data remain limited.</p><p><strong>Conclusions: </strong>Thromboprophylaxis from infancy to adolescence requires individualized age-specific and dynamic strategies that account for changing haemostatic profiles, cardiac anatomy, procedural exposure and sex-specific bleeding risks. Prospective paediatric studies are needed to optimize treatment selection and duration.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cardiologist's role in the age of artificial intelligence: A shift in practice rather than a revolution in mission.","authors":"Marc Villaceque, Stéphane Lafitte","doi":"10.1016/j.acvd.2026.07.003","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.07.003","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149118823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to letter by Das et al. regarding \"Direct oral anticoagulants versus vitamin K antagonists after heart valve bioprosthetic replacement or repair: A systematic review and meta-analysis\".","authors":"Vito D Bruno, Tom Lester, Enrico Poletti, Bleri Celmeta, Tommaso Viva, Arturo Bisogno, Antonio Miceli, Mattia Glauber","doi":"10.1016/j.acvd.2026.08.002","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.08.002","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflections on the ESC consensus statement on inflammation in coronary syndromes: From mechanistic certainty to practical cardiology.","authors":"François Roubille, Mark Nidorf, Jean-Claude Tardif","doi":"10.1016/j.acvd.2026.08.001","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.08.001","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}