Jacques Blacher , Valérie Olié , Laurence Amar , François Dievart , Béatrice Duly-Bouhanick
{"title":"Thoughts on the European Society of Cardiology 2024 guidelines for the management of elevated blood pressure and hypertension","authors":"Jacques Blacher , Valérie Olié , Laurence Amar , François Dievart , Béatrice Duly-Bouhanick","doi":"10.1016/j.acvd.2025.02.002","DOIUrl":"10.1016/j.acvd.2025.02.002","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 213-215"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ingrid Allagbé , Marianne Zeller , Daniel Thomas , Guillaume Airagnes , Frédéric Limosin , Abdelali Boussadi , Frédéric Chagué , Anne-Laurence Le Faou
{"title":"Response to a letter from Tomoyuki Kawada commenting on the article entitled “Sex-specific predictive factors of smoking cessation in subjects at high cardiovascular risk”","authors":"Ingrid Allagbé , Marianne Zeller , Daniel Thomas , Guillaume Airagnes , Frédéric Limosin , Abdelali Boussadi , Frédéric Chagué , Anne-Laurence Le Faou","doi":"10.1016/j.acvd.2024.12.015","DOIUrl":"10.1016/j.acvd.2024.12.015","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 272-273"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent Labbé , Stephane Ederhy , David Legouis , Jérémie Joffre , François Bagate , Oumar Sy , Frank Chemouni , Armand Mekontso Dessap , Muriel Fartoukh , Ariel Cohen , the FAST study group
{"title":"Left atrial appendage function after conversion to sinus rhythm in patients with sepsis-induced atrial fibrillation","authors":"Vincent Labbé , Stephane Ederhy , David Legouis , Jérémie Joffre , François Bagate , Oumar Sy , Frank Chemouni , Armand Mekontso Dessap , Muriel Fartoukh , Ariel Cohen , the FAST study group","doi":"10.1016/j.acvd.2024.12.014","DOIUrl":"10.1016/j.acvd.2024.12.014","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 268-270"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julie Lourtet-Hascoët , Jerome Van Rothem , Nicolas Combes , Benjamin Honton , Sébastien Hascoët , Jean-Louis Galinier , Benoit Fontenel , Hélène Charbonneau , Eric Bonnet
{"title":"Transcatheter aortic valve implantation: Association between skin flora and infective endocarditis?","authors":"Julie Lourtet-Hascoët , Jerome Van Rothem , Nicolas Combes , Benjamin Honton , Sébastien Hascoët , Jean-Louis Galinier , Benoit Fontenel , Hélène Charbonneau , Eric Bonnet","doi":"10.1016/j.acvd.2024.12.007","DOIUrl":"10.1016/j.acvd.2024.12.007","url":null,"abstract":"<div><h3>Background</h3><div>Infective endocarditis is a rare but severe complication that may arise following transcatheter aortic valve implantation. Recent advances in microbiological epidemiology have highlighted staphylococci and enterococci as the primary pathogens involved.</div></div><div><h3>Aim</h3><div>To investigate the prevalence of these bacteria in patients’ cutaneous flora before and after transcatheter aortic valve implantation procedures, and to assess the implications for antibiotic prophylaxis recommendations.</div></div><div><h3>Methods</h3><div>A single-centre prospective epidemiological study was conducted, enrolling patients admitted consecutively for transcatheter aortic valve implantation procedures between June 2021 and February 2022. Cutaneous samples were obtained from each patient at the puncture site of the transcatheter aortic valve implantation procedure, before and after skin detersion, and from operator hands after skin detersion.</div></div><div><h3>Results</h3><div>One hundred patients were included, with a mean age of 82<!--> <!-->±<!--> <!-->6.1<!--> <!-->years, a male-to-female ratio of 0.48 and a mean body mass index of 29<!--> <!-->±<!--> <!-->4.4<!--> <!-->kg/m<sup>2</sup>. Before skin detersion, cutaneous samples were positive in 58 patients; among them were coagulase-negative staphylococci (<em>n</em> <!-->=<!--> <!-->48, 82%, 95% confidence interval 71–91%), enterococci (<em>n</em> <!-->=<!--> <!-->12, 21%, 95% confidence interval: 11–33%), <em>Staphylococcus aureus</em> (<em>n</em> <!-->=<!--> <!-->2, 3%, 95% confidence interval 0–12%) and Enterobacteriaceae (<em>n</em> <!-->=<!--> <!-->4, 7%, 95% confidence interval: 2–17%).</div></div><div><h3>Conclusions</h3><div>Enterococci are frequently present in patients’ cutaneous flora at the puncture site before skin detersion, suggesting a potential source for infective endocarditis after transcatheter aortic valve implantation. These findings support considering amoxicillin-clavulanate as antibiotic prophylaxis before transcatheter aortic valve implantation procedures to mitigate the risk of infective endocarditis associated with enterococcal colonization.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 241-247"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maxime Nolf , Dominique Boulmier , Guillaume Leurent , Jacques Tomasi , Florent Le Bars , Abdelkader Bakhti , Sam Sharobeem , Léo Lemarchand , Gwenaelle Sost , Marielle Le Guellec , Hervé Le Breton , Vincent Auffret
{"title":"Early and late bleeding events according to Valve Academic Research Consortium 3 criteria following transcatheter aortic valve implantation","authors":"Maxime Nolf , Dominique Boulmier , Guillaume Leurent , Jacques Tomasi , Florent Le Bars , Abdelkader Bakhti , Sam Sharobeem , Léo Lemarchand , Gwenaelle Sost , Marielle Le Guellec , Hervé Le Breton , Vincent Auffret","doi":"10.1016/j.acvd.2024.12.009","DOIUrl":"10.1016/j.acvd.2024.12.009","url":null,"abstract":"<div><h3>Background</h3><div>Transcatheter aortic valve implantation may be associated with significant haemorrhagic complications.</div></div><div><h3>Aims</h3><div>To evaluate the timing, incidence, predictors and clinical impact of bleeding events after transcatheter aortic valve implantation, according to the updated Valve Academic Research Consortium (VARC)-3 criteria, compared with the VARC-2 criteria.</div></div><div><h3>Methods</h3><div>A retrospective observational study involving 487 consecutive patients who underwent transcatheter aortic valve implantation between July 2017 and May 2019 was performed. Bleeding events were classified according to the VARC-2 and VARC-3 definitions.</div></div><div><h3>Results</h3><div>Bleeding events occurred in 17.6% of patients, with early bleeding (in-hospital) in 12.5% and late bleeding (occurring after discharge) in 6.1%. The primary vascular access site was the most common source of early bleeding, whereas gastrointestinal bleeding was predominant in late events. Significant predictors of early VARC-3-defined bleeding included active cancer, previous implantable cardioverter-defibrillator, history of mitral valve surgery, a non-transfemoral approach and occurrence of an in-hospital major vascular complication or new-onset atrial fibrillation. Late bleeding was independently associated with a history of myocardial infarction and treatment with vitamin K antagonists at discharge. Early bleeding events were not associated with increased late all-cause mortality. No significant difference was observed based on the VARC-2 and VARC-3 bleeding definitions.</div></div><div><h3>Conclusions</h3><div>Bleeding events occurred in one sixth of patients undergoing transcatheter aortic valve implantation without significant difference in their incidence between the VARC-2 and VARC-3 classifications. Early bleeding events were not associated with poorer long-term survival, regardless of the classification used. Larger studies with greater statistical power, including more contemporary patients, are needed to confirm these findings.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 248-259"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Quentin Battistolo , Robin Le Ruz , Pierre-Guillaume Piriou , Patrice Guerin , Vincent Letocart , Julien Plessis , Alexandra Poinas , Thomas Senage , Thibaut Manigold
{"title":"Changes in microcirculation following transcatheter aortic valve implantation in patients with stable coronary artery disease","authors":"Quentin Battistolo , Robin Le Ruz , Pierre-Guillaume Piriou , Patrice Guerin , Vincent Letocart , Julien Plessis , Alexandra Poinas , Thomas Senage , Thibaut Manigold","doi":"10.1016/j.acvd.2024.12.006","DOIUrl":"10.1016/j.acvd.2024.12.006","url":null,"abstract":"<div><h3>Background</h3><div>Few studies have assessed coronary physiology in the setting of coronary artery disease (CAD) with severe aortic stenosis (AS). Fractional flow reserve (FFR) to guide revascularization in such patients is not validated.</div></div><div><h3>Aims</h3><div>We describe changes in coronary physiology in this population before and after transcatheter aortic valve implantation (TAVI).</div></div><div><h3>Methods</h3><div>Patients with stable CAD and severe AS treated with TAVI were prospectively included during 2020–2023. Coronary physiology was assessed before and immediately after TAVI, and at follow-up (median 5.4 months).</div></div><div><h3>Results</h3><div>Twenty-nine patients (mean age 81.3 years) were included. Median (95% confidence interval) FFR decreased numerically, from 0.83 (0.79–0.84) pre-TAVI to 0.81 (0.78–0.83) post-TAVI. During hyperaemia, the transit mean time reduced numerically, from 0.27 (0.19–0.35) to 0.20 (0.18–0.27) seconds, reflecting increased coronary flow. Basal microvascular resistance increased numerically, from 24 (21–35) to 32 (23–45), while resistive reserve ratio increased significantly, from 1.8 (1.5–2.3) to 2.6 (2.2–3.1) (<em>P</em> <!-->=<!--> <!-->0.002). Consequently, coronary flow reserve (CFR) improved significantly, from 1.5 (1.2–1.7) to 1.9 (1.5–2.4) (<em>P</em> <!-->=<!--> <!-->0.006). Among 21 patients with follow-up, no significant change in FFR was observed and the significance of the increase in CFR was lost. Only three patients had an index of microvascular resistance<!--> <!-->><!--> <!-->25, indicating microvascular impairment during hyperaemia.</div></div><div><h3>Conclusions</h3><div>In stable CAD patients treated with TAVI for severe AS, valve replacement provides an immediate improvement in CFR. FFR shows a minimal decrease after valve implantation, supporting its reproducibility to guide revascularization in such patients.</div></div><div><h3>Clinical trial registration</h3><div><em>.</em> <span><span>NCT04663334</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 222-230"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Smoking cessation, weight control and cardiovascular disease: Letter in response to the article entitled “Sex-specific predictive factors of smoking cessation in subjects at high cardiovascular risk” by Allagbé et al.","authors":"Tomoyuki Kawada","doi":"10.1016/j.acvd.2024.10.336","DOIUrl":"10.1016/j.acvd.2024.10.336","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Page 271"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterization of left atrial strain in left ventricular hypertrophy: A study of Fabry disease, sarcomeric hypertrophic cardiomyopathy and cardiac amyloidosis","authors":"Charles Massie , Frédérique Dubé , Soumaya Sridi-Cheniti , Julien Ternacle , Stéphane Lafitte , Patricia Réant","doi":"10.1016/j.acvd.2024.12.013","DOIUrl":"10.1016/j.acvd.2024.12.013","url":null,"abstract":"<div><h3>Background</h3><div>Patients with left ventricular hypertrophy (LVH) often maintain preserved left ventricular ejection fraction in the early stages of the disease. There is a need to identify simple and reliable variables beyond left ventricular ejection fraction to recognize those at risk of developing adverse clinical outcomes.</div></div><div><h3>Aims</h3><div>To examine left atrial (LA) strain in patients with hypertrophic cardiomyopathy (HCM), cardiac amyloidosis (CA) and Fabry disease (FD), pathologies known to cause LVH, and the relationship between LA strain and adverse clinical outcomes.</div></div><div><h3>Methods</h3><div>In this retrospective cohort study, LA strain was measured and compared among patients with HCM, CA and FD. Relationships between LA and left ventricular strain, and LA strain and adverse cardiovascular events were evaluated. The primary outcome was first occurrence of cardiovascular mortality, device implantation, heart failure hospitalization, new-onset atrial fibrillation or stroke.</div></div><div><h3>Results</h3><div>A total of 191 patients were included (24 with FD, 87 with HCM, 80 with CA). LA reservoir strain was highest in patients with HCM (26%, interquartile range [IQR] 20%, 32%), followed by those with FD (20.5%, IQR: 14%, 27.8%) and CA (11%, IQR: 7%, 18.8%) (<em>P</em> <!--><<!--> <!-->0.001). LA strain correlated well with left ventricular strain in patients with LVH, with CA showing the best correlation (<em>r</em> <!-->=<!--> <!-->−0.70, 95% confidence interval [95% CI]: −0.80 to −0.56; <em>P</em> <!--><<!--> <!-->0.001). Multivariable Cox regression analysis showed that LA reservoir strain was significantly associated with the primary outcome in all patients (hazard ratio: 0.91, 95% CI: 0.84 to 0.99; <em>P</em> <!-->=<!--> <!-->0.03) and in those with CA (hazard ratio: 0.90, 95% CI: 0.82 to 0.99; <em>P</em> <!-->=<!--> <!-->0.023).</div></div><div><h3>Conclusions</h3><div>LA strain was more reduced in CA than in FD and HCM, probably as a result of atrial wall infiltration, and was associated with adverse clinical outcomes in our heterogenous LVH population and patients with CA.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 231-240"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clément Boiteux , Simon Viscogliosi , Sinan Boissiere , Astrid Monier , Geoffroy Ditac , Roland Henaine , Olivier Metton , Antoine Deliniere , Rémi Thevenard , Nawel Babouri , Kévin Gardey , Francis Bessière
{"title":"Koch's triangle and coronary sinus anatomy assessed by three-dimensional electroanatomical mapping in paediatric patients with junctional tachycardia","authors":"Clément Boiteux , Simon Viscogliosi , Sinan Boissiere , Astrid Monier , Geoffroy Ditac , Roland Henaine , Olivier Metton , Antoine Deliniere , Rémi Thevenard , Nawel Babouri , Kévin Gardey , Francis Bessière","doi":"10.1016/j.acvd.2024.11.004","DOIUrl":"10.1016/j.acvd.2024.11.004","url":null,"abstract":"<div><h3>Background</h3><div>Three-dimensional electroanatomical mapping has become an essential tool in paediatric electrophysiology to precisely identify areas involved in arrhythmias. Anatomical variations in Koch's triangle, especially fluoroscopic enlargement of the coronary sinus ostium, have been found more frequently in patients with atrioventricular nodal reentrant tachycardia (AVNRT) than in those with atrioventricular reentrant tachycardia (AVRT). This finding is consistent with easier coronary sinus cannulation during electrophysiology procedures in patients with AVNRT.</div></div><div><h3>Aim</h3><div>To explore anatomical differences in the coronary sinus and Koch's triangle between children with AVNRT and AVRT using three-dimensional system acquisitions.</div></div><div><h3>Methods</h3><div>We conducted a single-centre retrospective study of paediatric patients undergoing a catheter ablation procedure for AVNRT or AVRT. Detailed anatomy of the coronary sinus ostium, global morphology and Koch's triangle properties was assessed via catheter-based intracardiac three-dimensional electroanatomical mapping, and compared.</div></div><div><h3>Results</h3><div>Forty-four children were enrolled (22 in each group). The median age was 14.6 (interquartile range [IQR] 10.9–16.2) years. The coronary sinus ostium area and diameter were similar in the AVNRT and AVRT groups: area, 1.0 (IQR 0.7–1.2) vs. 1.2 (IQR 0.5–1.6) cm/m<sup>2</sup>, respectively (<em>P</em> <!-->=<!--> <!-->0.71; 95% confidence interval of median difference –0.3 to 0.3); diameter, 1.0 (IQR 0.8–1.5) vs. 1.1 (IQR 0.9–1.4) cm/m<sup>2</sup>, respectively (<em>P</em> <!-->=<!--> <!-->0.56; 95% confidence interval of median difference –0.2 to 0.2). Five patients (22.7%) in each group had a coronary sinus with a windsock morphology. There was no difference in the Koch's triangle area between the AVNRT and AVRT groups: 1.4 (IQR 1.1–2.0) vs. 1.6 (IQR 1.3–1.9) cm<sup>2</sup>/m<sup>2</sup>, respectively (<em>P</em> <!-->=<!--> <!-->0.37; 95% CI of median difference –0.2 to 0.5).</div></div><div><h3>Conclusions</h3><div>Our findings suggest no difference in coronary sinus anatomy between these two junctional tachycardias. A potential explanation is the limited ability of three-dimensional mapping technologies to accurately define complex intracardiac structures.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 260-267"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}