Clemence Delhomme, Elodie Surget, Laurence Iserin, Bernard Iung
{"title":"2025 European Society of Cardiology guidelines for the management of cardiovascular disease and pregnancy.","authors":"Clemence Delhomme, Elodie Surget, Laurence Iserin, Bernard Iung","doi":"10.1016/j.acvd.2026.04.001","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.04.001","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patients implanted with a leadless pacemaker after transcatheter aortic valve implantation: Results from the MITAVI prospective study.","authors":"Nicolas Lellouche, Eloi Marijon, Vincent Algalarrondo, Romain Gallet, Madjid Boukantar, Tarvinder Dhanjal, Thibaut Moulin, Marina Urena, Chekrallah Chamandi, Jean-Philippe Collet, Estelle Gandjbakhch, Emmanuel Teiger","doi":"10.1016/j.acvd.2026.02.004","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.02.004","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter aortic valve implantation is a well-established clinical procedure for treating severe aortic stenosis. High-grade atrioventricular block has been reported in 10-30% of patients following transcatheter aortic valve implantation. Traditional transvenous pacemakers are associated with several potential complications, including endocarditis, lead dislodgement or fracture, pocket haematoma and tricuspid regurgitation. These risks may be mitigated with the use of leadless pacemakers.</p><p><strong>Aim: </strong>We proposed to evaluate the 1-year clinical and electrical outcomes of patients implanted with a leadless pacemaker following transcatheter aortic valve implantation.</p><p><strong>Methods: </strong>From July 2019 to December 2022, 102 patients from four French centres who underwent transcatheter aortic valve implantation and subsequently required pacemaker implantation with a leadless pacemaker (Micra; Medtronic, Dublin, Ireland) were evaluated prospectively.</p><p><strong>Results: </strong>The mean patient age was 82±9 years, and the mean baseline left ventricular ejection fraction was 58.4±10.6%. Major complications included one case of cardiac tamponade and one case of device migration. During 12-month follow-up, one patient required transvenous cardiac resynchronization therapy pacing because of severe heart failure. The all-cause death rate was 12%, and the heart failure hospitalization rate was also 12%. Compared with baseline, leadless pacemaker electrical variables improved at 1 year. Additionally, complete atrioventricular conduction restoration was observed in 38% of the cohort.</p><p><strong>Conclusions: </strong>Leadless pacemakers can be implanted in patients following transcatheter aortic valve implantation, with low complication rates and excellent electrical variables at 1-year follow-up. The need for an upgrade to a transvenous pacemaker was low (< 1%).</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emmie Lasik, Fabien Picard, Pierre Brami, Alain Cariou, Olivier Varenne, Vincent Pham
{"title":"Impact of initial angiographic coronary flow on survival after out-of-hospital cardiac arrest.","authors":"Emmie Lasik, Fabien Picard, Pierre Brami, Alain Cariou, Olivier Varenne, Vincent Pham","doi":"10.1016/j.acvd.2026.02.005","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.02.005","url":null,"abstract":"<p><strong>Background: </strong>Out-of-hospital cardiac arrest (OHCA) remains associated with poor outcomes despite advances in care. Coronary artery disease is the leading cause, yet the prognostic role of initial coronary flow status, assessed by Thrombolysis In Myocardial Infarction (TIMI) grade at angiography, has not been fully explored in OHCA survivors.</p><p><strong>Aim: </strong>To evaluate the prognostic impact of preprocedural TIMI flow in this population, and to identify predictive factors for reduced TIMI flow.</p><p><strong>Methods: </strong>We analysed data from the prospective PROCAT registry, including consecutive patients with OHCA with no extracardiac cause who underwent early coronary angiography between May 2016 and August 2022 at Cochin Hospital, Paris. Patients were categorized into three groups: non-ischaemic OHCA (OHCAni); ischaemic OHCA with preserved flow (TIMI 2-3; OHCAi2-3); and ischaemic OHCA with reduced flow (TIMI 0-1; OHCAi0-1). The primary endpoint was 1-year death; secondary endpoints included in-hospital death, neurological outcome at discharge and major bleeding (Bleeding Academic Research Consortium types 3-5).</p><p><strong>Results: </strong>Among 330 patients, 181 (55%) had OHCAni, 58 (18%) had OHCAi2-3 and 91 (27%) had OHCAi0-1. The 1-year death rate was significantly higher in the OHCAni group (66.7%) than in the ischaemic OHCA groups (OHCAi2-3, 34.5%; OHCAi0-1, 36.7%; P<0.001). Favourable neurological outcome (Cerebral Performance Category 1-2) at hospital discharge was observed in 64.4% of the OHCAni group versus 64.9% and 58.9% in the OHCAi2-3 and OHCAi0-1 groups, respectively (P<0.001). Major bleeding was more frequent in the OHCAi2-3 group (28.1%) than the OHCAi0-1 group (11.5%; P=0.02). In multivariable analysis restricted to ischaemic OHCA, reduced TIMI flow independently predicted 1-year death (odds ratio 2.58, 95% confidence interval 1.02-7.22; P=0.05), along with older age, longer low-flow duration and absence of shockable rhythm.</p><p><strong>Conclusions: </strong>Ischaemic and non-ischaemic OHCA represent distinct clinical entities, with markedly poorer outcomes in the non-ischaemic group. In ischaemic OHCA, reduced preprocedural TIMI flow is an independent predictor of 1-year death despite high procedural success rates. Early assessment of coronary flow may thus provide important prognostic information, and should be integrated into risk stratification models for OHCA survivors.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Lohse, Brahim Harbaoui, Anissa Bouali, Marco Vola, Clara Dolci, Bertrand Scheppler, Cyril Prieur, Thomas Bochaton, Ahmad Hayek
{"title":"Transcatheter edge-to-edge repair versus surgery in acute severe primary mitral regurgitation: A cardiac ICU experience.","authors":"Thomas Lohse, Brahim Harbaoui, Anissa Bouali, Marco Vola, Clara Dolci, Bertrand Scheppler, Cyril Prieur, Thomas Bochaton, Ahmad Hayek","doi":"10.1016/j.acvd.2026.03.120","DOIUrl":"https://doi.org/10.1016/j.acvd.2026.03.120","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sacha Mairet-Mabboux , Thibault Blache , Anthony Facchin , Catherine Koffel , Arnaud Ferraris , Christopher Blakeley , Vincent Piriou , Roland Henaine , Marc Lilot
{"title":"Patient outcomes associated with merging two paediatric cardiac intensive care units into one: A retrospective study","authors":"Sacha Mairet-Mabboux , Thibault Blache , Anthony Facchin , Catherine Koffel , Arnaud Ferraris , Christopher Blakeley , Vincent Piriou , Roland Henaine , Marc Lilot","doi":"10.1016/j.acvd.2025.09.006","DOIUrl":"10.1016/j.acvd.2025.09.006","url":null,"abstract":"<div><h3>Background</h3><div>In November 2020, a structural reorganization was implemented at our institution in Lyon, France, merging two paediatric cardiac intensive care units into a single multidisciplinary intensive care unit. This consolidation aimed to centralize perioperative care for children and neonates with congenital heart disease, and improve care coordination.</div></div><div><h3>Aim</h3><div>To assess whether this intensive care unit merger was associated with changes in hospital length of stay, morbidity and deaths among paediatric cardiac patients.</div></div><div><h3>Methods</h3><div>This retrospective study included paediatric patients hospitalized between 01 February 2020 and 22 November 2020 (Pre-merger group), and between 23 November 2020 and 17 September 2021 (Post-merger group). Patients were grouped by cardiopathy and type of surgery. The <em>t</em><em>-test</em>, Mann-Whitney test, χ<sup>2</sup> and Fisher's exact tests were used.</div></div><div><h3>Results</h3><div>A total of 310 Pre-merger patients and 327 Post-merger patients were included in the analysis. Post-merger patients with cardiopulmonary bypass had a reduced length of stay both in the intensive care unit (Δ mean: –2 days, 95% Confidence Interval: –4 to 0; <em>P</em> <!-->=<!--> <!-->0.03) and out of the intensive care unit (Δ mean: –1.3 days, 95% Confidence Interval: –2.5 to 0; <em>P</em> <!-->=<!--> <!-->0.04), resulting in a reduced overall length of stay at the hospital (Δ mean: –3.3 days, 95% Confidence Interval: –6 to –1; <em>P</em> <!-->=<!--> <!-->0.008) compared with Pre-merger patients with cardiopulmonary bypass. No difference was observed in survival in the intensive care unit (95% Pre-merger vs. 95% Post-merger; <em>P</em> <!-->=<!--> <!-->0.89) or in the hospital (95% Pre-merger vs. 94% Post-merger; <em>P</em> <!-->=<!--> <!-->0.66) or in the occurrence of any adverse event.</div></div><div><h3>Conclusions</h3><div>The merger was associated with a reduced hospital length of stay without increased morbidity or deaths. Structural reorganization may improve efficiency while preserving clinical safety in specialized paediatric settings.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"119 4","pages":"Pages 291-301"},"PeriodicalIF":2.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdalhakim Shubietah , Mohamed S. Elgendy , Hosam I. Taha , Ameer Awashra , Mohammad Alqadi , Emmanuel Olumuyide , Mohammad O. Abdelhafez , Jehad Zeidalkilani , Hasan Munshi , Qutaiba Qafisheh , Muath A. Baniowda , Mohammad Ghannam , Mohammed Tareq Mutar
{"title":"Geographic and demographic disparities in left–ventricular failure mortality, 1999–2020, with forecasts to 2040: A nationwide US analysis","authors":"Abdalhakim Shubietah , Mohamed S. Elgendy , Hosam I. Taha , Ameer Awashra , Mohammad Alqadi , Emmanuel Olumuyide , Mohammad O. Abdelhafez , Jehad Zeidalkilani , Hasan Munshi , Qutaiba Qafisheh , Muath A. Baniowda , Mohammad Ghannam , Mohammed Tareq Mutar","doi":"10.1016/j.acvd.2025.08.012","DOIUrl":"10.1016/j.acvd.2025.08.012","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"119 4","pages":"Pages 257-262"},"PeriodicalIF":2.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vaccination is as efficient as a cardiovascular drug! An editorial discussion of vaccination as “the new pillar in cardiovascular prevention”","authors":"François Roubille , Paul Loubet","doi":"10.1016/j.acvd.2025.08.007","DOIUrl":"10.1016/j.acvd.2025.08.007","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"119 4","pages":"Pages 251-254"},"PeriodicalIF":2.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter in response to the article entitled “Psychoactive drug use and prognosis in patients with cancer presenting with acute cardiovascular disease” by Jaëck et al.","authors":"Qianfeng Xiong","doi":"10.1016/j.acvd.2025.09.004","DOIUrl":"10.1016/j.acvd.2025.09.004","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"119 4","pages":"Page 311"},"PeriodicalIF":2.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145427225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}