Archives of Cardiovascular Diseases最新文献

{"title":"2023 SFMU/GICC-SFC/SFGG expert recommendations for the emergency management of older patients with acute heart failure. Part 1: Prehospital management and diagnosis","authors":"Nicolas Peschanski, Florian Zores, Jacques Boddaert, Bénedicte Douay, Clément Delmas, Amaury Broussier, Delphine Douillet, Emmanuelle Berthelot, Thomas Gilbert, Cédric Gil-Jardiné, Vincent Auffret, Laure Joly, Jérémy Guénézan, Michel Galinier, Marion Pépin, Philippe Le Conte, Nicolas Girerd, Frédéric Roca, Mathieu Oberlin, Patrick Jourdain, Geoffroy Rousseau, Nicolas Lamblin, Barbara Villoing, Frédéric Mouquet, Xavier Dubucs, François Roubille, Maxime Jonchier, Rémi Sabatier, Saïd Laribi, Muriel Salvat, Tahar Chouihed, Jean-Baptiste Bouillon-Minois, Anthony Chauvin, Société française de médecine d’urgence (SFMU), Groupe insuffisance cardiaque et cardiomyopathies de la Société française de cardiologie (GICC-SFC), Société française de gériatrie et gérontologie (SFGG)","doi":"10.1016/j.acvd.2024.08.002","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.08.002","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142225725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and clinical implications of a stepwise screening strategy for atrial fibrillation after stroke: Insights from the SAFAS study.","authors":"Karim Benali, Gauthier Duloquin, Cyril Noto-Campanella, Lucie Garnier, Romain Didier, Thibaut Pommier, Gabriel Laurent, Catherine Vergely, Yannick Béjot, Charles Guenancia","doi":"10.1016/j.acvd.2024.07.062","DOIUrl":"https://doi.org/10.1016/j.acvd.2024.07.062","url":null,"abstract":"<p><strong>Background: </strong>Although guidelines recommend screening patients for atrial fibrillation (AF) after stroke, the optimal timing and combination of screening tools remain unclear.</p><p><strong>Aims: </strong>We evaluated the suitability of a sequential combination of screening techniques for AF detected after stroke (AFDAS). We also compared patient characteristics according to the timing of AFDAS.</p><p><strong>Methods: </strong>Patients without previous AF admitted for acute ischaemic stroke were prospectively enrolled. After a stepwise screening approach for AFDAS based on electrocardiogram, telemetry monitoring and in-hospital long-term Holter, patients with cryptogenic stroke underwent implantation of an implantable cardiac monitor (ICM). Early AFDAS was defined as AF diagnosed during hospitalization and late AFDAS as AF diagnosed on an ICM.</p><p><strong>Results: </strong>Of the 240 patients included, 104 (43.3%) had a documented cause of stroke not related to AF. Among the 136 remaining patients, AFDAS was detected in 82 (60.3%) during the acute screening phase or during the 3-year follow-up by ICM. Early AFDAS was diagnosed by ECG, telemetry and in-hospital long-term Holter monitoring in 17 (20.7%), 25 (30.5%) and 18 (22.0%) patients, respectively. Among 76 patients who had an ICM implanted for cryptogenic stroke, AF was detected in 22 patients (28.9%). Except for age and stroke location, patients with early AFDAS did not differ from those with late AFDAS, particularly with regard to the prevalence of atrial cardiomyopathy markers.</p><p><strong>Conclusion: </strong>A stepwise approach to AFDAS screening allows early detection of AF in a considerable number of patients during their hospitalization. ICMs remain complementary to non-invasive screening tools for the detection of remote episodes of AF.</p>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ours FCPC","authors":"","doi":"10.1016/S1875-2136(24)00294-8","DOIUrl":"10.1016/S1875-2136(24)00294-8","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1875213624002948/pdfft?md5=8a92ab0766e53b32afb472ce544ff04f&pid=1-s2.0-S1875213624002948-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiogenic shock and infection: A lethal combination","authors":"Miloud Cherbi ,&nbsp;Hamid Merdji ,&nbsp;Vincent Labbé ,&nbsp;Eric Bonnefoy ,&nbsp;Nicolas Lamblin ,&nbsp;François Roubille ,&nbsp;Bruno Levy ,&nbsp;Pascal Lim ,&nbsp;Hadi Khachab ,&nbsp;Guillaume Schurtz ,&nbsp;Brahim Harbaoui ,&nbsp;Gerald Vanzetto ,&nbsp;Nicolas Combaret ,&nbsp;Benjamin Marchandot ,&nbsp;Benoit Lattuca ,&nbsp;Caroline Biendel-Picquet ,&nbsp;Guillaume Leurent ,&nbsp;Edouard Gerbaud ,&nbsp;Etienne Puymirat ,&nbsp;Laurent Bonello ,&nbsp;Clément Delmas","doi":"10.1016/j.acvd.2024.04.005","DOIUrl":"10.1016/j.acvd.2024.04.005","url":null,"abstract":"<div><h3>Background</h3><div>Cardiogenic shock and sepsis are severe haemodynamic states that are frequently present concomitantly, leading to substantial mortality. Despite its frequency and clinical significance, there is a striking lack of literature on the outcomes of combined sepsis and cardiogenic shock.</div></div><div><h3>Methods</h3><div>FRENSHOCK was a prospective registry including 772 patients with cardiogenic shock from 49 centres. The primary endpoint was 1-month all-cause mortality. Secondary endpoints included heart transplantation, ventricular assistance device and all-cause death rate at 1<!--> <!-->year.</div></div><div><h3>Results</h3><div>Among the 772 patients with cardiogenic shock included, 92 cases were triggered by sepsis (11.9%), displaying more frequent renal and hepatic acute injuries, with lower mean arterial pressure. Patients in the sepsis group required broader use of dobutamine (90.1% vs. 81.2%; <em>P</em> <!-->=<!--> <!-->0.16), norepinephrine (72.5% vs. 50.8%; <em>P</em> <!-->&lt;<!--> <!-->0.01), renal replacement therapy (29.7% vs. 14%; <em>P</em> <!-->&lt;<!--> <!-->0.01), non-invasive ventilation (36.3% vs. 24.4%; <em>P</em> <!-->=<!--> <!-->0.09) and invasive ventilation (52.7% vs. 35.9%; <em>P</em> <!-->=<!--> <!-->0.02). Sepsis-triggered cardiogenic shock resulted in higher 1-month (41.3% vs. 24.0%; adjusted hazard ratio: 1.94, 95% confidence interval: 1.36–2.76; <em>P</em> <!-->&lt;<!--> <!-->0.01) and 1-year (62.0% vs. 42.9%; adjusted hazard ratio 1.75, 95% confidence interval 1.32–2.33; <em>P</em> <!-->&lt;<!--> <!-->0.01) all-cause death rates. No significant difference was found at 1<!--> <!-->year for heart transplantation or ventricular assistance device (8.7% vs. 10.3%; adjusted odds ratio 0.72, 95% confidence interval 0.32–1.64; <em>P</em> <!-->=<!--> <!-->0.43). In patients with sepsis-triggered cardiogenic shock, neither the presence of a preexisting cardiomyopathy nor the co-occurrence of other cardiogenic shock triggers had any additional impact on death.</div></div><div><h3>Conclusions</h3><div>The association between sepsis and cardiogenic shock represents a common high-risk scenario, leading to higher short- and long-term death rates, regardless of the association with other cardiogenic shock triggers or the presence of preexisting cardiomyopathy.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141691402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PEACE-HYPNO – Management of procedural pain by multimodal sedation analgesia combining hypnosis in children with congenital heart disease: A randomized trial of non-inferiority","authors":"M. Gerard,&nbsp;E. Chambon","doi":"10.1016/j.acvd.2024.07.022","DOIUrl":"10.1016/j.acvd.2024.07.022","url":null,"abstract":"<div><h3>Introduction</h3><p>Children with congenital heart disease often undergo painful procedures due to surgeries and associated care. While medications are commonly used for pain management during procedures like chest tube removal, they can have side effects. Non-pharmacological methods, such as therapeutic hypnosis, have shown effectiveness in reducing procedural pain and anxiety in children. However, there is limited research in this area, particularly in children, and none in children with congenital heart disease.</p></div><div><h3>Objective</h3><p>The objective of this study is to prove the non-inferiority of therapeutic hypnosis as a co-analgesic compared to standard analgesics during intrathoracic drain removal in children with congenital heart disease.</p></div><div><h3>Methods</h3><p>This study is a non-inferiority, randomized, controlled trial. Patients are randomized by computer. One group receive the conventional analgesia protocol including ketamine, midazolam, and MEOPA. The other group only receives MEOPA and lower doses of ketamine and undergo a hypnosis session by one of the service's professionals trained in medical hypnosis. Patient pain is self-assessed before and after the procedure. Patients are filmed throughout the drain removal so that per-procedure pain can be blindly evaluated from the randomization arm at a distance from the intervention. Finally, indirect signs of pain (HR, RR, SpO₂) are recorded before, during, and after the intervention.</p><p>This study has been authorized by a French Committee of Ethics.</p><p>Clinicaltrial.gov: <span><span>NCT06373627</span><svg><path></path></svg></span>.</p></div><div><h3>Expected results</h3><p>Therapeutic hypnosis, when combined with minimal sedation-analgesia, is non-inferior to conventional sedation-analgesia in managing pain during chest tube removal in children with congenital heart disease.</p></div><div><h3>Perspectives</h3><p>This study would pave the way for wider adoption of therapeutic hypnosis as a co-analgesic method for children undergoing painful medical procedures, potentially reducing reliance on medications and enhancing patient experience.</p></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Independent external evaluation of pediatric HCM Risk Scores in predicting severe ventricular arrhythmias","authors":"M. Wilkin,&nbsp;V. Waldmann","doi":"10.1016/j.acvd.2024.07.012","DOIUrl":"10.1016/j.acvd.2024.07.012","url":null,"abstract":"<div><h3>Introduction</h3><p>Sudden cardiac death (SCD) is the most common cause of death in childhood hypertrophic cardiomyopathy (HCM). Recently, two risk scores have been developed to estimate the 5-year risk of SCD.</p></div><div><h3>Objective</h3><p>We aimed to assess their respective performances in an independent cohort of primary prevention children with HCM.</p></div><div><h3>Methods</h3><p>All patients with HCM<!--> <!-->&lt;<!--> <!-->18-year-old from a single-center were retrospectively included between 2003 and 2023. Secondary and syndromic causes of HCM were excluded as well as children with inaugural sustained ventricular arrythmias. HCM Risk-Kids and PRIMaCY risk scores were calculated at diagnosis and during follow-up. The primary composite outcome included sustained ventricular arrhythmia, appropriate ICD therapy, aborted cardiac arrest, or SCD.</p></div><div><h3>Results</h3><p>Hundred primary prevention children were included (mean age 7.1<!--> <!-->±<!--> <!-->5.6<!--> <!-->years, 59.0% males), with a mean follow-up of 8.6<!--> <!-->±<!--> <!-->5.5<!--> <!-->years.13 (13.0%) patients experienced the primary composite outcome. When only considering events during the 5 first years, Harrel's C index was 0.52 (95% CI: 0.27–0.77) for HCM Risk-Kids (≥<!--> <!-->6%) and 0.70 (95% CI: 0.59–0.80) for PRIMaCY (&gt;<!--> <!-->8.3%), with 1 patient potentially treated by ICD for every 25 ICDs implanted for HCM Risk Kids and 1 for every 14 ICDs implanted for PRIMaCY. When risk scores were repeated and all primary outcomes during follow-up considered, all events except one (93.2%) were correctly identified using both risk scores, with 1 patient potentially treated by ICD for every 5.6 ICDs implanted for HCM Risk Kids and 1 for every 5.3 ICDs implanted for PRIMaCY. Among 44 (44.0%) patients implanted with an ICD, all primary prevention patients who had<!--> <!-->≥<!--> <!-->one appropriate ICD therapy during follow-up had HCM Risk-Kids<!--> <!-->≥<!--> <!-->6% and PRIMaCY<!--> <!-->&gt;<!--> <!-->8.3% at implantation.</p></div><div><h3>Conclusion</h3><p>Our findings suggest imperfect discrimination between low and high-risk HCM patients using these two risk scores. The performance or risk scores was substantially improved by periodic re-assessment during follow-up.</p></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary hypertension induced by right pulmonary artery occlusion: Hemodynamic consequences of BMPR2 mutation","authors":"J. Grynblat ,&nbsp;A. Todesco ,&nbsp;F.K. Akoumia ,&nbsp;D. Bonnet ,&nbsp;P. Mendes-Ferreira ,&nbsp;M. Meot ,&nbsp;C. Vastel-Amzallag ,&nbsp;S. Malekzadeh-Milani ,&nbsp;B. Decante ,&nbsp;M. Levy ,&nbsp;S. Morisset ,&nbsp;M. Humbert ,&nbsp;D. Montani ,&nbsp;D. Boulate ,&nbsp;F. Perros","doi":"10.1016/j.acvd.2024.07.018","DOIUrl":"10.1016/j.acvd.2024.07.018","url":null,"abstract":"<div><h3>Introduction</h3><p>The primary genetic risk factor for heritable pulmonary arterial hypertension (PAH) is the presence of monoallelic mutations in the <em>BMPR2</em> gene. The incomplete penetrance of BMPR2 mutations implies that additional triggers are necessary for PAH occurrence. Pulmonary artery stenosis directly raises pulmonary artery pressure, while the redirection of blood flow to unobstructed arteries lead to endothelial dysfunction and vascular remodeling.</p></div><div><h3>Objective</h3><p>We aimed to evaluate the effect of right pulmonary artery occlusion (RPAO) in rats. Then, we evaluated the effect of BMPR2 loss of function on cardiac and pulmonary vascular remodeling.</p></div><div><h3>Methods</h3><p>Male and female rats with a 71<!--> <!-->bp monoallelic deletion in exon 1 of BMPR2 and their wild-type (WT) siblings underwent acute and chronic RPAO. They were subjected to full high-fidelity hemodynamic characterization. We also examined how chronic RPAO can mimic the pulmonary gene expression pattern associated with installed PH in unobstructed territories.</p></div><div><h3>Expected results</h3><p>RPAO induced pre-capillary PH in male and female rats, both acutely and chronically. BMPR2 mutant and male rats manifested more severe PH compared to their counterparts. While WT rats adapted to RPAO, BMPR2 mutant rats experienced heightened mortality. RPAO induced a decline in cardiac contractility index, particularly pronounced in male BMPR2 rats. Chronic RPAO resulted in elevated pulmonary interleukin-6 (IL-6) expression and decreased Gdf2 expression (corrected <em>P</em>-value<!--> <!-->&lt;<!--> <!-->0.05 and log2 fold change<!--> <!-->&gt;<!--> <!-->1). In this context, male rats expressed higher pulmonary levels of endothelin-1 and IL-6 than females (<span><span>Fig. 1</span></span>).</p></div><div><h3>Perspectives</h3><p>Our novel two-hit rat model presents a promising avenue to explore the adaptation of the right ventricle and pulmonary vasculature to PH, shedding light on pertinent sex and gene-related effects.</p></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatic valve disease in children still a burden in sub-Saharan Africa: Diagnostic, therapeutic and prognostic aspects in two hospitals in Central Africa subregion","authors":"J. Tony Nengom ,&nbsp;L. Madjile Baba ,&nbsp;A.P. Menanga ,&nbsp;D. Chelo ,&nbsp;P.O. Koki Ndombo","doi":"10.1016/j.acvd.2024.07.050","DOIUrl":"10.1016/j.acvd.2024.07.050","url":null,"abstract":"<div><h3>Introduction</h3><p>Rheumatic fever remains a public health problem in sub-Saharan Africa. Its impact on the heart valves is the main acquired cardiopathy in children in our environment.</p></div><div><h3>Objective</h3><p>The aim of our study was to investigate the diagnostic, therapeutic and prognostic aspects of rheumatic heart valve disease in children aged 0–18<!--> <!-->years in two hospitals in the city of Yaoundé.</p></div><div><h3>Methods</h3><p>We conducted a cross-sectional analytical study with retrospective and prospective data collection over a 5-years period (2018–2023). All patients aged 0 to 18<!--> <!-->years with an echocardiographically confirmed diagnosis of rheumatic valvulopathy in the cardiology departments of the Chantal Biya Foundation and the Yaoundé Central Hospital were included. We collected sociodemographic, clinical, paraclinical, therapeutic and outcome data.</p></div><div><h3>Results</h3><p>We recruited 106 patients, predominantly female (65.8%); mean age was 11.4<!--> <!-->±<!--> <!-->3 (4–18) years. The most common age group was 10 to 14 years (63.2%). Promiscuity (86.8%) and recurrent sore throat (68.4%) were the most common findings in the past history. Monovalvular involvement (mainly mitral valve) predominated in 60.5% of cases. The proportion of deaths in the population was 7.9%. After multivariate analysis, only the presence of cardiac liver and oedema of the lower limbs increased the risk of having a poor prognosis (OR<!--> <!-->&gt;<!--> <!-->1; <em>P</em> <!-->&lt;<!--> <!-->0.05).</p></div><div><h3>Conclusion</h3><p>The eradication of rheumatic valve disease in children necessarily involves early-prevention. This would involve cleaning up the living environment to prevent streptococcal infections and improving sociodemographic conditions.</p></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kills two birds with one stone: Biomechanical properties and three-dimensional modeling of human aortic root with new method of micro-CT","authors":"M. Lenoir ,&nbsp;T. Fringand ,&nbsp;C. Isabelle ,&nbsp;F. Julien ,&nbsp;M. Loïc ,&nbsp;S. Laurent","doi":"10.1016/j.acvd.2024.07.042","DOIUrl":"10.1016/j.acvd.2024.07.042","url":null,"abstract":"<div><h3>Introduction</h3><p>The micro-CT obtain very high-quality of the aortic roots and three-dimensional modeling of aortic leaflets. Different tests (biaxial test) are used to know the biomechanical properties. We propose a new method, which combines pressurization of the aortic root with micro-CT to obtain at the same time, the geometry, and biomechanical properties.</p></div><div><h3>Objective</h3><p>The aim is to investigate healthy aorta mechanical property using a micro-CT under pressure and compare them with literature.</p></div><div><h3>Methods</h3><p>This study was approved by committee on human research at the French agency of biomedicine (PFFS 20-026). Ten aortic roots were obtained fresh from unused donor hearts with non-cardiac causes of death. We used aortic root under pressure at different pressure level (every 20<!--> <!-->mmHg) in order to obtain diameter, geometry, stress-strain curve and Young modulus.</p></div><div><h3>Results</h3><p>All aortic roots (<em>n</em> <!-->=<!--> <!-->10) obtained a three-dimensional modeling of aortic leaflets with excellent quality. The mean age was 61.2<!--> <!-->years [49.5–65.6]. The median of sino-tubular junction diameter was 32.2<!--> <!-->mm [29–36] at 80<!--> <!-->mmHg. The non-linear stress-strain curves of healthy aortic root were characterized. Young moduli were significantly smaller in low pressure (between 20 and 80<!--> <!-->mmHg) 0.6 [0.5–0.8] MPa than high pressure (between 80 and 120<!--> <!-->mmHg) 3.2 [2.5–5.6] MPa, <em>P</em> <!-->=<!--> <!-->0.001 (<span><span>Fig. 1</span></span>).</p></div><div><h3>Conclusion</h3><p>Our new method allows a 3D model of the aortic root associated with measurements of biomechanical properties. Our results are found to be consistent with literature data. This new method evaluates the biomechanical properties while keeping the aortic roots intact and maintaining its geometrical complexity for future global aortic root simulation.</p></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142271255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac rehabilitation recommendations of the Group Exercise Rehabilitation Sports – Prevention (GERS-P) of the French Society of Cardiology: 2023 update","authors":"Muriel Bigot ,&nbsp;Jean Michel Guy ,&nbsp;Catherine Monpere ,&nbsp;Alain Cohen-Solal ,&nbsp;Bruno Pavy ,&nbsp;Marie Christine Iliou ,&nbsp;Gilles Bosser ,&nbsp;Sonia Corone ,&nbsp;Herve Douard ,&nbsp;Titi Farrokhi ,&nbsp;Antoine Guerder ,&nbsp;Pascal Guillo ,&nbsp;Jean-Pierre Houppe ,&nbsp;Theo Pezel ,&nbsp;Bernard Pierre ,&nbsp;Stephane Roueff ,&nbsp;Daniel Thomas ,&nbsp;Benedicte Verges ,&nbsp;Jean Christophe Blanchard ,&nbsp;Mohamed Ghannem ,&nbsp;Dany Marcadet","doi":"10.1016/j.acvd.2024.05.119","DOIUrl":"10.1016/j.acvd.2024.05.119","url":null,"abstract":"","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}