Audiology and Neuro-Otology最新文献

{"title":"Sudden Traumatic Noise Exposure Induces an Altered Wave I in the Auditory Brainstem Response in Human.","authors":"Elenor Lundgren, Eleonor Koro, Åsa Kjellgren, Sten Hellström, Fredrik Öhberg, Mimmi Werner","doi":"10.1159/000553367","DOIUrl":"10.1159/000553367","url":null,"abstract":"<p><strong>Introduction: </strong>Noise trauma may induce auditory symptoms and temporary or permanent shifts in hearing thresholds, assessed with a tone audiogram. Until recently it has been assumed that primary changes after noise trauma exclusively represent damage to the sensory hair cells. Contrary, animal studies have now shown early alterations in auditory brainstem response (ABR) characteristic of auditory neuropathy (AN), as reduction or absence of wave I, following noise trauma. AN involves a variety of disease mechanisms in the cochlea and auditory nerve, affecting the synaptic encoding and/or neural transmission of auditory information. The aim of this study was to evaluate whether patients exposed to noise trauma exhibit click ABR alterations characteristic of AN.</p><p><strong>Method: </strong>Thirty-one adult patients who attended an ear-nose and throat clinic, after a noise trauma, were included and an age- and gender-matched control group of 31 adults was constructed. To evaluate audiologic hearing impairment pure tone audiometry, speech intelligibility, click ABR and transient evoked otoacoustic emissions (TEOAE)/cochlear microphonics (CM) were performed. A full linear mixed model including the interaction between sex and group was tested.</p><p><strong>Results: </strong>Our study showed that individuals exposed to sudden and distinct traumatic noise exhibit a statistically significant reduction (81.1 nV, p < 0.001) in the amplitude of wave I in ABR.</p><p><strong>Conclusion: </strong>We suggest that the hearing investigation after sudden traumatic noise exposure should therefore be expanded with ABR to confirm or exclude AN.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-14"},"PeriodicalIF":1.4,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13485285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148363822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Test Equivalency of the Spanish and English AzBio Sentences among Bilingual Normal Hearers.","authors":"Sandra Prentiss, Sandra Velandia, Sebastian Ausili, Brianna Kuzbyt, Hillary Snapp","doi":"10.1159/000551152","DOIUrl":"10.1159/000551152","url":null,"abstract":"<p><strong>Introduction: </strong>Language influences speech perception in bilingual listeners, with non-native languages often requiring higher signal-to-noise ratios (SNRs) for comprehension. Structural features, such as phonology and syllabic rhythm, make Spanish easier to perceive in noise compared to English, which relies more heavily on high-frequency cues and complex consonant clusters. These differences have clinical implications, particularly for individuals with hearing loss, as speech-in-noise tasks guide treatment decisions, including amplification and cochlear implant candidacy. However, most assessment tools were developed for English speakers, limiting their accuracy for individuals with limited English proficiency. Spanish-language tests, such as the AzBio, often use low-context Spanish sentences presented with English babble, creating a linguistic mismatch that increases informational masking and cognitive load. This can reduce speech intelligibility, misrepresent actual hearing abilities, and potentially contribute to healthcare disparities. Addressing these limitations requires evaluation of how target language, masker language, and sentence structure influence speech perception in bilingual populations to ensure valid assessment and equitable access to hearing healthcare.</p><p><strong>Methods: </strong>Twenty normal-hearing bilingual adults (mean age 32 years, 65% male) who were fluent in both English and Spanish participated in the study. Participants were classified as English- or Spanish-dominant based on self-report and proficiency measures. Speech-in-noise testing was assessed using the English and Spanish versions of the Hearing in Noise Test (HINT) and AzBio sentence test. An additional condition was included using the Spanish AzBio sentences presented with Spanish multi-talker babble.</p><p><strong>Results: </strong>Bilingual listeners required significantly higher SNRs for English than Spanish tests (HINT mean difference = 2.77 dB, 95% Highest Density Interval [HDI]: 1.64-3.88; AzBio mean difference = 2.5 dB, 95% HDI: -3.54 to -1.53). No overall differences emerged between Spanish AzBio with English versus Spanish babble; however, subgroup analyses revealed language-dominant effects. Spanish-dominant listeners performed worse when target and masker were both Spanish (mean difference = -1.64 dB, 95% HDI: -2.78 to -0.48), whereas English-dominant listeners showed greater difficulty with English stimuli. Higher self-reported proficiency in a given language correlated with lower SNRs on corresponding measures.</p><p><strong>Conclusions: </strong>Language dominance and structural features of Spanish versus English significantly affect bilinguals' speech perception in noise. These findings underscore the need for linguistically appropriate test materials, as reliance on English-only tools may misrepresent communication abilities and contribute to disparities in hearing healthcare.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-11"},"PeriodicalIF":1.4,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148213442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Localisation by Impedance.","authors":"Alhassan Algazlan, Marzouqi Salamah, Dalal Alrushaydan, Hassan Yalcouy, Abdulrahman Hagr, Fida Almuhawas","doi":"10.1159/000548171","DOIUrl":"10.1159/000548171","url":null,"abstract":"<p><strong>Background: </strong>Accurate intracochlear positioning of electrode arrays is critical for optimizing auditory outcomes during cochlear implantation (CI). While radiographic imaging remains the standard for postoperative evaluation, transimpedance matrix (TIM) measurements have emerged as a promising intraoperative technique for real-time assessment of electrode placement, particularly with a slim modiolar electrode array.</p><p><strong>Methods: </strong>This retrospective observational study included 15 patients (24 ears) who underwent CI using CI532® and CI632® electrode arrays. Intraoperative TIM data were obtained and compared with intraoperative and immediate postoperative radiographic imaging data to determine the accuracy and reliability of TIM in detecting electrode placement anomalies. The electrode positioning patterns were analyzed using TIM heatmaps, with a focus on the voltage gradient distribution and identification of the electrode tip fold-over (TFO).</p><p><strong>Results: </strong>Of the 24 CIs, 23 (96%) exhibited a regular TIM voltage distribution consistent with proper modiolar placement. A single instance of TFO (4%) was identified intraoperatively using TIM and confirmed via radiographic imaging. The electrode was reinserted following intraoperative correction with TIM and imaging, subsequently confirming the optimal placement. In all remaining cases, the TIM findings were in concordance with radiological assessments.</p><p><strong>Conclusion: </strong>TIM may be a reliable intraoperative monitoring tool for CI using slim modiolar CI532® and CI632® electrode arrays position during CI. Their ability to accurately detect deviations in electrode configuration, such as the TFO, affirms their potential to augment surgical precision, eliminate the need of intraoperative radiation exposure by providing real-time feedback, minimize postoperative imaging requirements, and enhance patient outcomes. Further prospective studies with larger cohorts are warranted to validate these preliminary findings and establish standardized protocols for clinical implementation.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"47-55"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of the ForwardFocus Feature in Cochlear Implant Patients in Noisy Environments.","authors":"Medhat Yousef, Mada Aljabr, Mariam Al-Amro, Dalal Alrushaydan, Hassan Yalcouy, Farid Alzhrani","doi":"10.1159/000549703","DOIUrl":"10.1159/000549703","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to assess the effectiveness of the ForwardFocus (FF) feature in cochlear implant (CI) users by evaluating its impact on speech comprehension in noisy environments, potentially improving communication outcomes for individuals with hearing loss.</p><p><strong>Methods: </strong>A prospective study was conducted on 48 CI users from an audiology clinic over a 7-month period, between July 2023 and February 2024. Native Arabic speakers, using either N7 or Kanso2 external processors with the FF feature, were recruited. The study measured aided audiometry, word recognition score, and speech comprehension in noise using the Arabic Matrix Test with and without the FF feature, along with a survey assessing ease of use and satisfaction among other factors.</p><p><strong>Results: </strong>The impact of FF on speech perception and user experience in CI users were evaluated. FF significantly improved speech perception in noise (p < 0.001), with users reporting high satisfaction (54.3% very satisfied, 26.1% satisfied) and intention to continue using FF (97.8%). Most participants used FF 1-2 times a week (56.5%), with 17% using it daily. Most found its noise reduction to be adequate (82.6%).</p><p><strong>Conclusion: </strong>FF effectively enhanced speech understanding, with users expressing high satisfaction and intention to continue using the feature. This suggests FF's ability to improve communication and quality of life for CI users.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"188-198"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear Implantation in Ménière's Disease.","authors":"Justin Cottrell, Arianna Winchester, David Friedmann, Sean McMenomey, J Thomas Roland, Daniel Jethanamest","doi":"10.1159/000547572","DOIUrl":"10.1159/000547572","url":null,"abstract":"<p><p><p>Introduction: Cochlear implantation has demonstrated benefit for restoring hearing in patients with Ménière's disease. We sought to examine disease and management factors that may influence postoperative speech performance and vertigo control.</p><p><strong>Methods: </strong>A single-center retrospective chart review between 2010 and 2023 of patients with Ménière's disease receiving a cochlear implant (CI). The primary outcome was 1-year postoperative word recognition score on Consonant-Nucleus-Consonant (CNC) testing. Postoperative vertigo control was assessed as a secondary outcome. Variables including concurrent labyrinthectomy, pre- and postoperative Ménière's disease symptoms and treatments, duration of deafness, and hearing loss laterality were analyzed.</p><p><strong>Results: </strong>Twenty-five patients were identified over the study period. Of those, 9 (36%) also underwent labyrinthectomy; 6 (67%) were performed simultaneously with CI and 3 (33%) received a CI following surgical ablation. There was a statistically significant (p = 0.03) higher rate of bilateral Ménière's disease in the CI-only cohort (n = 9, 56%), compared to the cochlear implant and labyrinthectomy (CI + L) cohort (n = 1, 11%). There was also a higher rate of preoperative uncontrolled vertigo (n = 5, 56%) in the CI + L cohort compared to the CI-only cohort (n = 3, 20%), although this did not reach statistical significance (p = 0.08). The average pre- and postoperative CNC score for the CI + L cohort was 3.6 (SD 5.9) and 36.7 (SD 17.5), respectively, and 7.1 (SD 10.1) and 62.1 (SD 14.3) for the CI-only group. There was a statistically significant difference noted at most recent CNC follow-up testing (p = 0.01) between the CI + L and CI-only group.</p><p><strong>Conclusion: </strong>Patients with Ménière's disease meeting CI candidacy criteria may undergo CI safely and achieve speech performance benefit. A trend toward worse performance in patients who undergo concurrent labyrinthectomy with CI compared to CI alone was seen which warrants further study. </p>.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"19-26"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Cervical Vestibular Evoked Myogenic Potential Responses to Different Stimuli at Different Frequencies.","authors":"Ercan Karababa, Betül Özdemir Aktaş, Fatma Ceyda Akın Öçal, Bülent Satar","doi":"10.1159/000549267","DOIUrl":"10.1159/000549267","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare cervical vestibular evoked myogenic potentials (cVEMP) elicited by tone burst (TB) and narrow band level-specific chirp (NB LS-CE Chirp) stimuli at 500, 1,000, 2,000, and 4,000 Hz in healthy individuals.</p><p><strong>Methods: </strong>Thirty-two healthy participants (15 females, 17 males; mean age: 24.59 ± 1.93 years) underwent otoscopic examination, pure-tone audiometry, and cVEMP testing at 95 dB nHL using TB and NB LS-CE Chirp stimuli. P1 latency, N1 latency, and P1N1 amplitude were recorded.</p><p><strong>Results: </strong>At 500 Hz, both stimuli elicited responses in all subjects. Significant differences in P1 latency, N1 latency, and P1N1 amplitude were found between the stimuli at 500 and 1,000 Hz (p < 0.05). No significant differences were observed at 2,000 and 4,000 Hz (p > 0.05).</p><p><strong>Conclusion: </strong>NB LS-CE Chirp stimuli generate larger and earlier cVEMP responses than TB stimuli, particularly at lower frequencies, suggesting higher effectiveness for saccular assessment.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"81-90"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audiometric Outcomes and Longitudinal Trends of Sequential Cochlear Implantation in Adults with Bilateral Deafness: A 20-Year Single-Center Study.","authors":"Sarek A Shen, Zahra N Sayyid, Nicholas S Andresen, Courtney Carver, Dawn D Marsiglia, Jennifer Yeagle, Charles Della Santina, Steve P Bowditch, Daniel Q Sun","doi":"10.1159/000551866","DOIUrl":"10.1159/000551866","url":null,"abstract":"<p><p><p>Introduction: In this study, we examine the outcomes and trends of second-side cochlear implant (CI) in adults as measured by change in speech perception scores, with a focus on those meeting age requirements for Medicare.</p><p><strong>Methods: </strong>This is a retrospective cohort study performed at a tertiary academic center. The investigation included adult patients with bilateral hearing loss receiving sequential, bilateral CI between 2001 and 2020. Bilateral speech perception scores under best aided conditions were compared following first- and second-side CI using Arizona Biomedical (AzBio) Sentence Test, Consonant-Nucleus-Consonant word (CNC-W), and Hearing in Noise Test (HINT). Individual changes in audiometric scores and trends in implant age and inter-implant interval were evaluated.</p><p><strong>Results: </strong>A total of 162 individuals were included in this study. 50 patients with AzBio scores, 40 patients with HINT scores, and 72 patients with CNC-W scores demonstrated mean improvements of 11.8 (95% CI: [5.7-17.9]), 6.7 (95% CI: [0.4-13.7]), 12.0 (SD: 25.3), and 11.5 (95% CI: [7.3-15.7]) points, respectively, following second-sided CI. Patients aged 65 and older experienced similar magnitude of improvement as younger patients (t-tests: AzBio: 95% CI: [-16.7, 17.4]; HINT: 95% CI: [-34.6, 0.5]; CNC-W: 95% CI: [-10.7, 13.1]). Longer time interval between implants was associated with reduced improvement in CNC-W in the overall population (β: -2.9, 95% CI: [-5.5 to -1.2]) and the elderly population (β: -4.24, 95% CI: [-6.1 to -2.8]) specifically. Over time, there were no significant changes in age of CI-1 implant or audiometric scores after bilateral CI, but there was a decrease in inter-implant interval.</p><p><strong>Conclusions: </strong>Intervention with a second-sided cochlear implant was associated with improved speech recognition scores and this benefit extended to patients aged 65 and over. Decreased inter-implant interval is associated with an increase in improvement. </p>.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"307-315"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13165502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147790059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the Regenerative Pattern in the Human Tympanic Membrane.","authors":"Elnaz Sepehri, Cecilia Engmér Berglin, Yan Liu, Per Olof Eriksson, Magnus von Unge, Julia Arebro","doi":"10.1159/000547944","DOIUrl":"10.1159/000547944","url":null,"abstract":"<p><p><p>Introduction: The reason why chronic tympanic membrane (TM) perforations fail to heal is an enigma. A better insight into the premises and cellular events in this process is fundamental. Previous large studies on human TMs are lacking. The main objective of the present study was to map potential stem cells in the human TM and to address the regenerative capacity in the TM keratinocytes. Further, the study aimed to assess the regenerative premises for three regions of the TM: the malleus, the annulus, and the unattached portion of the pars tensa (UPT), including different anatomical levels (inferior, intermediate, and superior) within each region.</p><p><strong>Methods: </strong>Ten healthy human TMs were harvested during lateral skull base surgery. Using immunohistochemistry, the TMs were stained for α6 and β1 integrin, CK19, p63, and Ki-67. Semi-quantification was made with two single-blinded observers scoring the staining of the slides. Inter-rater reliability was evaluated with weighted Cohen's kappa, and group differences between the mean grading were further calculated.</p><p><strong>Results: </strong>Antibodies for α6 and β1 integrin, CK19, p63, and Ki-67 could be detected along the malleus, annulus, and UPT of human TMs displaying diversity in the regenerative capacity of the human TM. The staining of Ki-67 and p63 was more prevalent in the annulus and malleus compared to in the UPT. α6 staining was more prevalent in the annulus, while CK19 staining was more prevalent in the malleus. Finally, several antibodies displayed a higher staining intensity in the inferior anatomical levels of the TM.</p><p><strong>Conclusion: </strong>The present study shows the presence of putative stem cells in all regions of the human TM, with a stronger regenerative capacity close to the annulus and malleus compared to the UPT. These findings may set a baseline for the localization and diversity of putative stem cells in the human TM. </p>.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"37-46"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144876911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Machine Learning to Predict Cochlear Implant Outcomes.","authors":"Madeleine Anthonisen, Diane S Lazard, Alexandre Lehmann","doi":"10.1159/000550216","DOIUrl":"10.1159/000550216","url":null,"abstract":"<p><strong>Introduction: </strong>Cochlear implant outcomes vary widely and are difficult to predict, with traditional methods explaining <20% of variance. This study tested whether machine learning approaches offer superior performance predicting outcomes and better identify key factors driving variability compared to traditional linear methods.</p><p><strong>Methods: </strong>This retrospective observational study analyzed clinical data from 2,251 adult cochlear implant recipients (>18 years) with post-lingual hearing loss (onset >15 years) across fifteen centers in Australia, Europe, and North America. Data were collected between 2003 and 2011, with follow-up at 6 months and 2 years post-implantation. Linear regression was compared against seven other machine learning models: eXtreme Gradient Boosting (XGBoost), random forest, categorical boosting (CatBoost), Light Gradient Boosting Machine (LightGBM), support vector regression, ridge regression, and Lasso regression. Models were optimized using grid search with 5-fold cross-validation on an 80/20 training-test split. The primary outcome was prediction of percentile-ranked postoperative speech recognition scores in quiet, assessed using mean-squared error (MSE) and coefficient of determination (R2). SHapley Additive exPlanations values identified feature importance.</p><p><strong>Results: </strong>XGBoost achieved the best performance with a modest but significant 4.11% reduction in prediction error compared to linear regression (MSE: 739.67 ± 19.27 vs. 771.41 ± 21.51, p = 0.003; R2: 0.114 ± 0.011 vs. 0.076 ± 0.012, p < 0.001). All ensemble methods significantly outperformed linear regression. Duration of cochlear implant use, age at implantation, duration of severe/profound hearing loss, and preoperative hearing scores emerged as the most influential predictors across all models.</p><p><strong>Conclusions: </strong>Machine learning models modestly improve cochlear implant outcome prediction, though substantial variance remains unexplained (>80%). Critical determinants of cochlear implant performance likely extend beyond variables routinely measured in clinical practice, highlighting the need for novel predictive factors.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"208-217"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Speech Recognition in Noise in Patients with Type 2 Diabetes Mellitus in a Tertiary Care Hospital: A Cross-Sectional Analytical Study.","authors":"Susana Iqbal, Mohan Kumar Kalaiah, Meera Niranjan Khadilkar, Maria Jose, Deviprasad Dosemane","doi":"10.1159/000550913","DOIUrl":"10.1159/000550913","url":null,"abstract":"<p><p><p>Introduction: Type 2 diabetes mellitus (T2DM) is associated with multiple systemic complications, including vascular and neuropathic changes that can affect the auditory pathway. These alterations may contribute to hearing loss and difficulty in speech perception, particularly in noisy environments. This study aimed to evaluate speech recognition in noise among patients with T2DM using the Signal-to-Noise Ratio 50 (SNR-50) and to examine its relationship with disease duration and glycemic control.</p><p><strong>Methods: </strong>An analytical cross-sectional study was conducted at a tertiary care hospital. Ninety subjects aged 30-60 years were recruited, comprising 45 patients with T2DM and 45 age-matched nondiabetic controls. All participants underwent audiological evaluation including pure-tone average (PTA), tympanometry, speech reception threshold (SRT), speech identification score (SIS), uncomfortable loudness level (UCL), and SNR-50 testing. Data were analyzed to assess differences between groups and correlations with diabetes duration and glycemic control (HbA1c levels).</p><p><strong>Results: </strong>PTA values were higher in patients with T2DM compared to controls, indicating worse peripheral hearing. Diabetic patients demonstrated poorer speech perception, confirmed by elevated SRT values. SNR-50 values were significantly impaired in T2DM patients relative to controls. Longer duration of diabetes (>10 years) was associated with reduced SIS and higher PTA and SRT values compared to patients with 5-10 years of disease. A statistically significant positive correlation was observed between SNR-50 and duration of diabetes. While PTA, SRT, and SIS did not show significant variation across HbA1c categories, SNR-50 values worsened significantly with poorer glycemic control.</p><p><strong>Conclusion: </strong>T2DM is associated with impaired speech perception and poorer hearing outcomes, with disease duration exerting a cumulative adverse effect. SNR-50 performance was significantly related to glycemic control, suggesting that subtle central auditory dysfunction may coexist with or precede peripheral hearing loss in diabetic patients. Early evaluation of auditory function in T2DM may aid in timely identification and management of communication difficulties. </p>.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"218-223"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13008384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}