Audiology and Neuro-Otology最新文献

{"title":"Atraumatic Surgical Approaches to the Vestibular Labyrinth Allowing for Drug Delivery, Cochleovestibular Implants, and Other New Surgical Applications.","authors":"Marta Álvarez de Linera-Alperi, Fergio Sismono, Morgana Sluydts, Bert de Foer, Raquel Manrique-Huarte, Ángel Ramos Macias, Manuel Manrique, Andrzej Zarowski","doi":"10.1159/000547032","DOIUrl":"10.1159/000547032","url":null,"abstract":"<p><strong>Introduction: </strong>Balance disorders are a major challenge today as they greatly affect people's quality of life. Although medical treatment and vestibular rehabilitation are insufficient in many cases, significant improvements in the treatment of vestibular pathologies have been achieved in recent decades. New trends toward minimally invasive procedures have led to the study of direct treatment at the vestibular level, such as the use of vestibular implants. Great efforts have been made to acquire a thorough knowledge of these organs. However, the surgical anatomy and exact spatial orientation of the vestibular end organs remain partially unknown. The aim of this study was to evaluate in three-dimensional (3D) reconstructions the feasibility of new minimally traumatic surgical approaches to the vestibule.</p><p><strong>Methods: </strong>In order to plan and explore new surgical approaches to the vestibular end organs, a methodology based on 3D models of the inner ear has been developed. This methodology is tested on human temporal bones treated with vestibular implants to analyze possible new minimally traumatic approaches to the vestibular system. Pre- and post-implantation cone-beam computed tomography (CBCT) images were acquired. Image segmentation of the vestibular end organs was performed on the pre-implantation CBCT scan. An already validated, freely and openly available anatomical atlas of the inner ear, IE-Map, was used as a reference template for the anatomy. Alignment of the IE-Map with the CBCT images was achieved using the MATLAB image processing toolbox. Interactive 3D models were visualized with the non-commercial version of Dragonfly 2021.1 software.</p><p><strong>Results: </strong>Image segmentation of the vestibular end organs and their 3D reconstructions were successfully performed in all cases. The 3D images showed reasonably realistic estimation of the location of the electrode within the vestibule and their relationships with respect to the different ampullary and otolithic receptors.</p><p><strong>Conclusion: </strong>3D reconstruction by segmentation of the inner ear with superposition of CT images and an anatomical model is feasible and offers valuable morphological insight into the complex anatomy of the inner ear. This technique is particularly useful for exploring potential new surgical approaches to access the vestibule and shows promising results in the context of future local drug delivery and/or direct electrical stimulation at the vestibular level. Three such approaches were proposed and preliminarily assessed.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-13"},"PeriodicalIF":1.3,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Silent Effects of Loud Music: Examining Hidden Hearing Loss and Cognitive Function in Young Adults.","authors":"Sema Satıcı, Ayşe Ayça Çiprut, Ali Cemal Yumuşakhuylu","doi":"10.1159/000547033","DOIUrl":"10.1159/000547033","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates whether high levels of headphone music listening in young adults contribute to hidden hearing loss (HHL) and whether listening effort (LE) and cognitive skills differ based on headphone exposure.</p><p><strong>Methods: </strong>Fifty participants (18-30 years) with normal hearing were divided into high-risk (HR) and low-risk (LR) groups based on annual headphone exposure levels recorded via smartphone applications. Participants underwent high-frequency audiometry, auditory brainstem response (ABR), matrix sentence test, behavioral LE measurement, and P300 testing. The measurement of LE and P300 was conducted at varying signal-to-noise ratio (SNR). Working memory was assessed using the reading span test, while attention abilities were evaluated with the Stroop test. Finally, short-term memory was assessed through the visual auditory number sequences test.</p><p><strong>Results: </strong>The findings from the ABR and matrix sentence tests indicated signs of noise-induced cochlear synaptopathy in the HR group. In this group, an increase in LE was observed as SNR decreased, which was statistically significant. Furthermore, a significant decrease in P300 amplitude was found in response to SNR changes in the HR group; however, no significant difference was observed in the LR group. Statistical analysis revealed no significant differences between the two groups in the cognitive tests administered.</p><p><strong>Conclusions: </strong>The present study lends support to the hypothesis that the habitual listening of music at high volumes through headphones has the potential to result in HHL; however, further longitudinal studies are required to assess the impact of this condition on cognitive skills.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-11"},"PeriodicalIF":1.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal Bone Meningoencephalocele Associated with Cholesteatoma: Systematic Literature Review and a Case Series.","authors":"Amit Wolfovitz, Omer Shaked, Idit Tessler","doi":"10.1159/000546748","DOIUrl":"10.1159/000546748","url":null,"abstract":"<p><strong>Background: </strong>Temporal bone meningoencephalocele (TB-MEC) diagnosed with or following cholesteatoma is a rare yet complex neurotological scenario. This study aimed to characterize the clinical features and treatment strategies to facilitate clinicians' decision-making and patients' counseling.</p><p><strong>Methods: </strong>We conducted a retrospective case series with a systematic literature review of the past 3 decades. For the literature review, PRISMA guidelines were followed, with articles sourced from PubMed and EMBASE. The study examined demographics, clinical aspects, imaging findings, surgical approaches, and postoperative outcomes.</p><p><strong>Results: </strong>We identified 75 cases (n = 72 from the literature and n = 3 original). The majority of the patients with TB-MEC had prior cholesteatoma surgeries (79%), mostly canal wall down (CWD) mastoidectomy, with a relatively high complication rate (15%) at presentation. TB-MECs were incidentally discovered intraoperatively in 39.5% of the cases. Most (65%) of the preoperatively diagnosed had major defects (>1 cm). Tegmen mastoideum was involved in 68%. Surgical treatment employed a trans-mastoid approach in 72%, including minor and major defects, whereas middle fossa or combined approaches were reserved for major defects only. Autologous grafts, mainly temporalis fascia, were the primary choice for reconstruction (98%), regardless of defect sizes or surgical approach. Single surgery was mostly sufficient, irrespective of defect size (100% and 93% for minor and major defects), and complications were minimal.</p><p><strong>Conclusions: </strong>Despite advancements in imaging, TB-MED is still discovered intraoperatively at a substantial rate. High-risk cases are patients with prior complications and multiple past surgeries, mainly CWD. Although previously described complications were ominous, today, a single-stage procedure yields positive outcomes.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-10"},"PeriodicalIF":1.6,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Saccadic Abnormalities in Multiple Sclerosis Using a Novel Clinical Saccadometry Test.","authors":"Zahra Polat, Ahmet Alperen Akbulut, Sema Satıcı, Reyhan Sürmeli, Mehmet Sürmeli","doi":"10.1159/000546670","DOIUrl":"10.1159/000546670","url":null,"abstract":"<p><strong>Introduction: </strong>The clinical saccadometry test is an ocular motor test that provides a functional assessment of the brain regions and circuits involved in the generation of saccadic eye movements. Clinical saccadometry is thought to be more sensitive to concussions and neurodegenerative disorders. The aim of our study was to compare healthy individuals with individuals diagnosed with relapsing-remitting multiple sclerosis (RRMS) using a saccadometry test, and to evaluate pro-saccade and anti-saccade performances.</p><p><strong>Methods: </strong>The study included 32 patients (mean age: 41 ± 11.88 years) between the ages of 18-60 years with relapsing remitting multiple sclerosis (RRMS), and a healthy control group of 28 individuals (mean age: 37.3 ± 12.2 years). Spontaneous nystagmus, gaze, random saccade, pursuit, and optokinetic and saccadometry tests included in the videonystagmography (VNG) test battery were performed for all participants.</p><p><strong>Results: </strong>There were no significant differences in random saccade (RS) latencies between the groups (p > 0.05). However, the pro-saccade and anti-saccade latencies were significantly prolonged in the multiple sclerosis (MS) group (p < 0.05). There were no statistically significant differences between the groups in peak velocity and accuracy for random saccades, pro-saccades, and anti-saccades (p > 0.05). Directional error rates in the pro-saccade and anti-saccade tests were significantly different between the MS and control groups (p < 0.05).</p><p><strong>Conclusion: </strong>The findings of our study show that there are significant differences in saccadometry test results between MS patients and healthy participants. Therefore, the clinical saccadometry test, which is newly added to the VNG test battery and offers short and noninvasive evaluation, could be included in the vestibular test battery for neurodegenerative diseases such as MS.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-12"},"PeriodicalIF":1.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Oral Steroids for Sudden Sensorineural Hearing Loss: Considerations of Age, Time to Treatment, and Degree of Hearing Loss.","authors":"Erin Harvey, Grace Callan, Neil Osafo, David Friedland, Michael S Harris, Jazzmyne Adams, Kristen Osinski, Ling Tong, Jake Luo","doi":"10.1159/000545672","DOIUrl":"10.1159/000545672","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to compare outcomes of oral steroids (OSs) to intratympanic (IT) steroids for treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) in a retrospective cohort study at a tertiary academic center.</p><p><strong>Methods: </strong>Patients diagnosed with ISSNHL receiving at least one course of OS between January 2009 and February 2022 were reviewed. OS patients were compared to a previously reported cohort of 74 patients who underwent IT treatment.</p><p><strong>Interventions: </strong>OS or IT steroid therapies are used for treating ISSNHL. Full, partial, or no recovery rates of hearing thresholds stratified by modality of treatment, age, degree of hearing loss, and time to initiation of treatment were measured.</p><p><strong>Results: </strong>There were 96 patients treated with OS and 74 patients treated with IT steroid. Full recovery was more frequent in patients who underwent OS therapy (43.8%) compared to IT therapy (25.68%, p = 0.017). For patients under 40 years old, full recovery rates were similar between OS (60.0%) and IT (61.5%). In patients over 40 years old, however, full recovery was seen in 40.7% of patients on OS and 18% for IT. Further, while those over 65 years had the worst rates of full recovery to IT steroid (<20%), this age group had a 50% full recovery rate with OSs. Additional factors correlating with response to both OS and IT treatments included degree of hearing loss and time to starting steroids.</p><p><strong>Conclusion: </strong>OS therapy was associated with greater likelihood of full recovery in all patient age groups compared to those treated with IT steroid alone, in combination with OS, or for salvage. A significant difference in response was seen in those over 65 years raising consideration of age stratification in decision-making for steroid modality in treatment of ISSNHL.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-9"},"PeriodicalIF":1.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Comorbidities on Cochlear Implantation Outcomes in Adults under 60.","authors":"Jamie A Schlacter, Christine Schremp, Allen Khudaverdyan, Emily R Spitzer, Susan B Waltzman","doi":"10.1159/000546569","DOIUrl":"10.1159/000546569","url":null,"abstract":"<p><strong>Introduction: </strong>Prior studies have demonstrated that comorbid conditions can negatively impact cochlear implantation (CI) outcomes in elderly patients, but few have examined how comorbidities affect younger adult CI recipients. This study examines the relationship between comorbidities and CI outcomes in adults under 60 years old.</p><p><strong>Methods: </strong>We reviewed all CI recipients between 20 and 60 years old from 2015 to 2019 at a tertiary academic medical center. Patient data were collected including comorbidities, demographics, etiology, and length of deafness (LOD). Patients' Charlson Comorbidity Index (CCI) was calculated. The primary outcome was speech perception scores at 1 year on the consonant-nucleus-consonant (CNC) word test.</p><p><strong>Results: </strong>There were 118 patients who underwent CI (20-29 years [15%], 30-39 years [22%], 40-49 years [21%], 50-60 years [42%]), averaging 1.8 comorbidities. Mean LOD was 19.7 years, and most etiologies were unknown (53.4%). 34% had no comorbidities, and the most frequent comorbidities were hypertension (14%), asthma (10%), anxiety (8%), acoustic neuroma (8%), and arthritis (7%). Comorbidity frequency was similar across ages, but cardiovascular comorbidities varied by patient decade (50-60 years: 41% vs. 20-49 years: 12-22%, p = 0.004). Compared to studies on elderly CI outcomes, our cohort had fewer comorbidities with reduced cardiac events and neurological conditions. We did not find differences in 1-year CNC scores or complications based on the number of comorbidities or any single comorbidity. However, there was a difference in individual improvement in CNC word scores by age group (p = 0.024). Patients' CCI did not correlate to post-op scores.</p><p><strong>Conclusion: </strong>Subjects showed improved speech understanding post-CI. The number and type of comorbidities were not meaningful predictors of 1-year speech perception scores, suggesting adult CI users under 60 years with comorbidities can expect comparable outcomes to those without comorbidities.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-10"},"PeriodicalIF":1.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1159/000543746","DOIUrl":"10.1159/000543746","url":null,"abstract":"","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"294"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12143843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between the International Outcome Inventory for Hearing Aids Questionnaire and Real-Ear Measurement.","authors":"Gi-Sung Nam, Young Jae Lee, Hansoo Song, Jeonghyun Oh, Sung Il Cho","doi":"10.1159/000540738","DOIUrl":"10.1159/000540738","url":null,"abstract":"<p><strong>Introduction: </strong>The international outcome inventory for hearing aids (IOI-HA) is a questionnaire widely used to assess the subjective benefits of hearing aids. This study aimed to evaluate the relationship between IOI-HA outcomes and target mismatch in real-ear measurement (REM).</p><p><strong>Methods: </strong>Thirty-four ears of 25 patients who had worn hearing aids were evaluated using the Korean version of the IOI-HA and REM after fitting for 2 months. Real-ear insertion gain (REIG) was measured at three different levels of input intensity - 50, 65, and 80 dB sound pressure level (SPL) - and a frequency range of 0.25-6 kHz. Factors 1 and 2 and total IOI-HA scores were compared with the mismatches of REIGs and target gains of REM.</p><p><strong>Results: </strong>Factor 1, factor 2, and total IOI-HA scores were 14.6 ± 3.5, 11.4 ± 2.2, and 25.9 ± 5.1, respectively. The averages of the difference of REIGs and target gains in REM at 50, 65, and 80 dB SPL input levels were -3.1 ± 6.7, -2.3 ± 7.2, and -3.0 ± 8.2, respectively. Factors 1 and 2 scores of the IOI-HA showed significant correlations with target mismatch in REM at 1 kHz and 0.75 kHz frequencies, respectively. Total IOI-HA scores had significant correlations with target mismatches in REM at 0.75 and 1 kHz frequencies.</p><p><strong>Conclusion: </strong>IOI-HA scores correlated with target mismatch in REM at mid frequencies. The IOI-HA can be a useful screening measure for evaluating the necessity of further adjustments in hearing aids through REM at mid frequencies.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"52-57"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra-Cochlear Electrode Position Impacts the Preservation of Residual Hearing in an Animal Model of Cochlear Implant Surgery.","authors":"Max Meuser, Susanne Schwitzer, Mario Thiele, Patrick Boyle, Arne Ernst, Dietmar Basta","doi":"10.1159/000540266","DOIUrl":"10.1159/000540266","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Preservation of residual hearing after cochlear implantation remains challenging. There are several approaches to preserve residual hearing, but the configuration of the implant electrode array seems to play a major role. Lateral wall electrode arrays are seemingly more favorable in this context. To date, there are no experimental data available which correlate the spatial electrode position in the scala tympani with the extent of hearing preservation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Based on micro-computed tomography (µCT) imaging data, this study analyses the exact position of a pure silicone electrode array inserted into the cochlea of four guinea pigs. Array position data were correlated with the extent of hearing loss after implantation, measured using auditory brainstem measurements in the frequency range of the area occupied by the electrode array area as well as apical to the array.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The use of pure silicone arrays without electrodes resulted in artifact-free, high-resolution µCT images that allowed precise determination of the arrays' positions within the scala tympani. The electrode arrays' locations ranged from peri-modiolar to an anti-modiolar. These revealed a correlation of a lower postoperative hearing loss with a higher spatial proximity to the lateral wall. This correlation was found in the low-frequency range only. A significant correlation between the inter-individual differences in the diameter of the scala tympani and the postoperative hearing loss could not be observed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This study demonstrates the importance of the intra-cochlear electrode array's position for the preservation of residual hearing. The advantage of such an electrode array's position approximated to the lateral wall suggests, at least for this type of electrode array applied in the guinea pig, it would be advantageous in the preservation of residual hearing for the apical part of the cochlea, beyond the area occupied by the electrode array.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Preservation of residual hearing after cochlear implantation remains challenging. There are several approaches to preserve residual hearing, but the configuration of the implant electrode array seems to play a major role. Lateral wall electrode arrays are seemingly more favorable in this context. To date, there are no experimental data available which correlate the spatial electrode position in the scala tympani with the extent of hearing preservation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Based on micro-computed tomography (µCT) imaging data, this study analyses the exact position of a pure silicone electrode array inserted into the cochlea of four guinea pigs. Array position data were correlated with the extent of hearing loss after implantation, measured using auditory brainstem measurements in the frequency range of the area occupied by the electrode array area as well as apical to the array","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"34-44"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141565193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Speech Perception Outcomes with the Anatomy-Based Fitting Map among Experienced, Adult Cochlear Implant Users: A Longitudinal Study.","authors":"Pelden Wangchuk, Cila Umat, Foong Yen Chong, Faizah Mohd Zaki, Asma Abdullah","doi":"10.1159/000540965","DOIUrl":"10.1159/000540965","url":null,"abstract":"<p><strong>Introduction: </strong>Anatomy-based fitting (ABF), a relatively new technique for cochlear implant (CI) programming, attempts to lessen the impact of the electrode insertion location-related frequency-to-place mismatch (FPM). This study aimed to compare vowels and consonant perception in quiet and in noise among experienced adult CI users using the ABF and the regular, conventional-based fitting (CBF) map (pre-ABF) over 6 months.</p><p><strong>Methods: </strong>Nine ears from eight experienced adult CI users were included in the experimental and longitudinal research. Using surgical planning software called Otoplan, postoperative computed computed tomography scans were used to determine the locations of intracochlear electrodes and their angle of insertion. The anatomy-based frequency bands were produced by Maestro 9.0 CI fitting software using the Otoplan data. Nonsense syllables with consonant-vowel-consonant (CVC) recognition scores in quiet and noise (+5 dB SNR) were compared at baseline, 3, and 6 months after ABF. The vowels involved were /a, i, u/, while the consonants were voiced /b, d, g/ and voiceless /p, t, k/ plosives. Speech pieces were presented at 30 dB SL in a sound-treated room through a loudspeaker positioned at 0° azimuth.</p><p><strong>Results: </strong>On average, the ABF maps shifted center frequency ranging from 0.46 semitones (0.04 octave) at (E12) to 23.94 semitones (1.99 octave) at (E1) as compared to the CBF maps. The mean vowel and consonant identification scores in quiet and in noise were significantly higher in ABF than in CBF (p < 0.05) with a large effect size and the trend of improvement was seen with time. Voiced consonants had better scores than the voiceless consonants.</p><p><strong>Conclusion: </strong>The results demonstrated improved perception of vowels and consonants, particularly for sounds containing voicing cues after using the ABF maps. The results also suggested that ABF could be more effective for voice detection in noise. Overall, the findings indicate that correcting place mismatch with an ABF map may improve speech perception, at least among experienced adult CI users.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"222-236"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}