{"title":"Auditory Performance and Cortical Plasticity Following Late Sequential Cochlear Implantation.","authors":"Hüseyin Deniz","doi":"10.1159/000547204","DOIUrl":"https://doi.org/10.1159/000547204","url":null,"abstract":"<p><strong>Introduction: </strong>Bilateral cochlear implantation (CI) may be performed either simultaneously or sequentially, depending on factors such as the degree of hearing loss and the patient's age. However, a global consensus regarding the optimal timing for sequential implantation has yet to be established.</p><p><strong>Methods: </strong>This study included 27 individuals who underwent late sequential CI. The mean chronological age of the participants was 140.93 ± 41.51 months. The mean age at the time of the first (early unilateral) CI 1 was 25.44 ± 9.25 months, with a mean interimplant interval of 115.48 ± 41.45 months before the second (late sequential) implantation (CI 2). Cortical auditory evoked potentials (CAEPs) were recorded, and P1 latency measurements were obtained at 3, 6, 9, and 12 months following CI 2 activation. Auditory performance outcomes were analyzed across five time points post-implantation.</p><p><strong>Results: </strong>Auditory perception improved markedly within 3 months after CI 2 activation. CAEP analysis demonstrated significant enhancements in cortical responsiveness, indicating that CI 2 had a beneficial effect on central auditory system plasticity. The reduction in P1 latency was statistically significant (p < 0.001), supporting the notion of cortical reorganization following late implantation.</p><p><strong>Conclusion: </strong>Late sequential CI can lead to substantial gains in auditory performance and may facilitate adaptive cortical plasticity in individuals with a history of early unilateral implantation. These findings support the clinical value of late second implantation, even after extended interimplant delays.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-14"},"PeriodicalIF":1.6,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qusai Tawakkul, Shahad Alsanosi, Asma Alahmadi, Sarah Alarifi, Murad Al-Momani, Ahmad Aldhafeeri, Salman Alhabib
{"title":"Comparative Outcomes of Cochlear Implantation in Children with Auditory Neuropathy Spectrum Disorder and Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis.","authors":"Qusai Tawakkul, Shahad Alsanosi, Asma Alahmadi, Sarah Alarifi, Murad Al-Momani, Ahmad Aldhafeeri, Salman Alhabib","doi":"10.1159/000546962","DOIUrl":"https://doi.org/10.1159/000546962","url":null,"abstract":"<p><strong>Background: </strong>Cochlear implantation (CI) has emerged as a promising intervention for children with auditory neuropathy spectrum disorder (ANSD). Several studies have investigated the efficacy of cochlear implants in children with ANSD, demonstrating improvements in auditory performance and language skills following implantation. Whether the benefits and outcomes of CIs in children with ANSD are comparable to children with sensorineural hearing loss (SNHL) is still debatable. The present updated systematic review and meta-analysis evaluated the outcomes of CI for children with ANSD compared to children with SNHL.</p><p><strong>Methods: </strong>A meta-analysis was conducted on studies that included pediatric patients and the outcomes of CI in patients with ANSD versus SNHL were compared. A comprehensive search was performed using the following electronic databases: PubMed, Scopus, Web of Science, EBSCOhost, and Cochrane Central Register of Controlled Trials (CENTRAL).</p><p><strong>Results: </strong>. Fourteen studies (no. of patients =722 patients) were included. The total number of patients in the ANSD and SNHL groups in the present systematic review was 212 and 520, respectively. The most utilized assessment tests were the Speech Intelligibility Rating (SIR) and Categories of Auditory Performance (CAP) scores. The pooled estimate showed that patients with ANSD had comparable CAP scores compared to patients with SNHL (MD -0.52, 95% CI [-1.34, 0.29], P =0.21,). Likewise, three studies reported the SIR after CI and showed comparable findings between ANSD and SNHL patients. The pooled estimate showed that patients with ANSD had comparable SIR scores compared to patients with SNHL (MD -0.26, 95% CI [-0.65, 0.13], P =0.19).</p><p><strong>Conclusion: </strong>While the results show mixed findings across various outcome measures, the overall impact of CI on speech recognition and language development appears to be positive and comparable between ANSD and SNHL.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-19"},"PeriodicalIF":1.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Álvarez de Linera-Alperi, Fergio Sismono, Morgana Sluydts, Bert de Foer, Raquel Manrique-Huarte, Ángel Ramos Macias, Manuel Manrique, Andrzej Zarowski
{"title":"Atraumatic surgical approaches to the vestibular labyrinth allowing for drug delivery, cochleo-vestibular implants, and other new surgical applications.","authors":"Marta Álvarez de Linera-Alperi, Fergio Sismono, Morgana Sluydts, Bert de Foer, Raquel Manrique-Huarte, Ángel Ramos Macias, Manuel Manrique, Andrzej Zarowski","doi":"10.1159/000547032","DOIUrl":"https://doi.org/10.1159/000547032","url":null,"abstract":"<p><strong>Introduction: </strong>Balance disorders are a major challenge today, as they greatly affect people's quality of life. Although medical treatment and vestibular rehabilitation are insufficient in many cases, significant improvements in the treatment of vestibular pathologies have been achieved in recent decades. New trends towards minimally invasive procedures have led to the study of direct treatment at the vestibular level, such as the use of vestibular implants. Great efforts have been made to acquire a thorough knowledge of these organs. However, the surgical anatomy and exact spatial orientation of the vestibular end organs, remain partially unknown. The aim of this study is to evaluate in three-dimensional (3D) reconstructions the feasibility of new minimally traumatic surgical approaches to the vestibule.</p><p><strong>Methods: </strong>In order to plan and explore new surgical approaches to the vestibular end organs, a methodology based on 3D models of the inner ear has been developed. This methodology is tested on human temporal bones treated with vestibular implants to analyze possible new minimally traumatic approaches to the vestibular system. Pre- and post-implantation cone-beam computed tomography (CBCT) images were acquired. Image segmentation of the vestibular end organs was performed on the pre-implantation CBCT scan. An already validated, freely and openly available anatomical atlas of the inner ear, IE-Map, was used as a reference template for the anatomy. Alignment of the IE-Map with the CBCT images was achieved using the MATLAB image processing toolbox. Interactive 3D models were visualized with the non-commercial version of Dragonfly 2021.1 software.</p><p><strong>Results: </strong>Image segmentation of the vestibular end organs and their 3D reconstructions were successfully performed in all cases. The 3D images showed reasonably realistic estimation of the location of the electrode within the vestibule and their relationships with respect to the different ampullary and otolithic receptors.</p><p><strong>Conclusion: </strong>3D reconstruction by segmentation of the inner ear with superposition of CT images and an anatomical model is feasible and offers valuable morphological insight into the complex anatomy of the inner ear. This technique is particularly useful for exploring potential new surgical approaches to access the vestibule and shows promising results in the context of future local drug delivery and/or direct electrical stimulation at the vestibular level. Three such approaches were proposed and preliminarily assessed.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-20"},"PeriodicalIF":1.6,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sema Satıcı, Ayşe Ayça Çiprut, Ali Cemal Yumuşakhuylu
{"title":"The Silent Effects of Loud Music: Examining Hidden Hearing Loss and Cognitive Function in Young Adults.","authors":"Sema Satıcı, Ayşe Ayça Çiprut, Ali Cemal Yumuşakhuylu","doi":"10.1159/000547033","DOIUrl":"https://doi.org/10.1159/000547033","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates whether high levels of headphone music listening in young adults contribute to hidden hearing loss (HHL) and whether listening effort (LE) and cognitive skills differ based on headphone exposure.</p><p><strong>Methods: </strong>Fifty participants (18-30 years) with normal hearing were divided into high-risk (HR) and low-risk (LR) groups based on annual headphone exposure levels recorded via smartphone applications. Participants underwent high-frequency audiometry, ABR, matrix sentence test, behavioural LE measurement, and P300 testing. The measurement of LE and P300 was conducted at varying signal-to-noise ratio (SNR). Working memory was assessed using the reading span test, while attention abilities were evaluated with the Stroop test. Finally, short-term memory was assessed through the visual auditory number sequences test.</p><p><strong>Results: </strong>The findings from the ABR and matrix sentence tests indicated signs of noise-induced cochlear synaptopathy in the HR group. In this group, an increase in LE was observed as SNR decreased, which was statistically significant. Furthermore, a significant decrease in P300 amplitude was found in response to SNR changes in the HR group; however, no significant difference was observed in the LR group. Statistical analysis revealed no significant differences between the two groups in the cognitive tests administered.</p><p><strong>Conclusions: </strong>The present study lends support to the hypothesis that the habitual listening of music at high volumes through headphones has the potential to result in HHL; however, further longitudinal studies are required to assess the impact of this condition on cognitive skills.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-21"},"PeriodicalIF":1.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Temporal Bone Meningoencephalocele Associated with Cholesteatoma: Systematic Literature Review and a Case Series.","authors":"Amit Wolfovitz, Omer Shaked, Idit Tessler","doi":"10.1159/000546748","DOIUrl":"10.1159/000546748","url":null,"abstract":"<p><strong>Background: </strong>Temporal bone meningoencephalocele (TB-MEC) diagnosed with or following cholesteatoma is a rare yet complex neurotological scenario. This study aimed to characterize the clinical features and treatment strategies to facilitate clinicians' decision-making and patients' counseling.</p><p><strong>Methods: </strong>We conducted a retrospective case series with a systematic literature review of the past 3 decades. For the literature review, PRISMA guidelines were followed, with articles sourced from PubMed and EMBASE. The study examined demographics, clinical aspects, imaging findings, surgical approaches, and postoperative outcomes.</p><p><strong>Results: </strong>We identified 75 cases (n = 72 from the literature and n = 3 original). The majority of the patients with TB-MEC had prior cholesteatoma surgeries (79%), mostly canal wall down (CWD) mastoidectomy, with a relatively high complication rate (15%) at presentation. TB-MECs were incidentally discovered intraoperatively in 39.5% of the cases. Most (65%) of the preoperatively diagnosed had major defects (>1 cm). Tegmen mastoideum was involved in 68%. Surgical treatment employed a trans-mastoid approach in 72%, including minor and major defects, whereas middle fossa or combined approaches were reserved for major defects only. Autologous grafts, mainly temporalis fascia, were the primary choice for reconstruction (98%), regardless of defect sizes or surgical approach. Single surgery was mostly sufficient, irrespective of defect size (100% and 93% for minor and major defects), and complications were minimal.</p><p><strong>Conclusions: </strong>Despite advancements in imaging, TB-MED is still discovered intraoperatively at a substantial rate. High-risk cases are patients with prior complications and multiple past surgeries, mainly CWD. Although previously described complications were ominous, today, a single-stage procedure yields positive outcomes.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-10"},"PeriodicalIF":1.6,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahra Polat, Ahmet Alperen Akbulut, Sema Satıcı, Reyhan Sürmeli, Mehmet Sürmeli
{"title":"Evaluation of Saccadic Abnormalities in Multiple Sclerosis Using a Novel Clinical Saccadometry Test.","authors":"Zahra Polat, Ahmet Alperen Akbulut, Sema Satıcı, Reyhan Sürmeli, Mehmet Sürmeli","doi":"10.1159/000546670","DOIUrl":"10.1159/000546670","url":null,"abstract":"<p><strong>Introduction: </strong>The clinical saccadometry test is an ocular motor test that provides a functional assessment of the brain regions and circuits involved in the generation of saccadic eye movements. Clinical saccadometry is thought to be more sensitive to concussions and neurodegenerative disorders. The aim of our study was to compare healthy individuals with individuals diagnosed with relapsing-remitting multiple sclerosis (RRMS) using a saccadometry test, and to evaluate pro-saccade and anti-saccade performances.</p><p><strong>Methods: </strong>The study included 32 patients (mean age: 41 ± 11.88 years) between the ages of 18-60 years with relapsing remitting multiple sclerosis (RRMS), and a healthy control group of 28 individuals (mean age: 37.3 ± 12.2 years). Spontaneous nystagmus, gaze, random saccade, pursuit, and optokinetic and saccadometry tests included in the videonystagmography (VNG) test battery were performed for all participants.</p><p><strong>Results: </strong>There were no significant differences in random saccade (RS) latencies between the groups (p > 0.05). However, the pro-saccade and anti-saccade latencies were significantly prolonged in the multiple sclerosis (MS) group (p < 0.05). There were no statistically significant differences between the groups in peak velocity and accuracy for random saccades, pro-saccades, and anti-saccades (p > 0.05). Directional error rates in the pro-saccade and anti-saccade tests were significantly different between the MS and control groups (p < 0.05).</p><p><strong>Conclusion: </strong>The findings of our study show that there are significant differences in saccadometry test results between MS patients and healthy participants. Therefore, the clinical saccadometry test, which is newly added to the VNG test battery and offers short and noninvasive evaluation, could be included in the vestibular test battery for neurodegenerative diseases such as MS.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-12"},"PeriodicalIF":1.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justus Müller-Goebel, Rahel Bertschinger, Nathalie Nierobisch, David Bächinger, Flurin Pfiffner, Christof Röösli, Alexander Huber, Adrian Dalbert
{"title":"Radiologically Assessed Stapes Footplate Thickness and Audiologic Outcomes in Patients with Otosclerosis.","authors":"Justus Müller-Goebel, Rahel Bertschinger, Nathalie Nierobisch, David Bächinger, Flurin Pfiffner, Christof Röösli, Alexander Huber, Adrian Dalbert","doi":"10.1159/000545673","DOIUrl":"10.1159/000545673","url":null,"abstract":"<p><strong>Introduction: </strong>Otosclerosis is a known cause of particularly conductive hearing loss of a variable extent. Radiological examination reveals footplate thickening in addition to heterogeneously distributed hypodense foci. The objective of this study was to investigate the correlation between a thickened stapes footplate and its association with perioperative audiometric findings and postoperative complications.</p><p><strong>Methods: </strong>This was a retrospective data analysis conducted at a single tertiary referral center on 63 surgically confirmed otosclerotic ears from 56 patients. Stapes footplate thickness was measured in the stapes axial plane of a preoperative computed tomography scan. Measured stapes footplate thickness was assessed regarding its relationship between pre- and postoperative audiometric data and vestibulocochlear complications associated with stapedotomy.</p><p><strong>Results: </strong>Radiological assessment of stapes footplate thickness demonstrated considerable variation between otosclerotic ears, with a mean value of 0.85 mm (range 0.5-1.37 mm). No statistically significant correlation was identified between pre- and postoperative audiometric data for air-bone gap, air conduction, and bone conduction in the overall population or within subgroups. One case showed postoperative inner ear hearing loss (PTA-BC 26.3-37.5 dB HL), resulting in severe combined hearing loss, occurring 40 days after uneventful surgery (footplate thickness 0.79). Regardless of footplate thickness, no further cases of postoperative sensorineural hearing loss were reported. Postoperative vertigo was observed in 20 patients, none of whom showed pathological findings in clinical head impulse testing or exhibited spontaneous nystagmus, without association with footplate thickness (t(61) = 0.83, p = 0.41). Significant improvements regarding the air-bone gap (26.45 dB HL, SD 9.24 to 7.70 dB HL, SD 5.69, p < 0.0001), as well as air-conduction (48.65 dB HL, SD 14.24-26.29 dB HL, SD 10.24, p < 0.0001) and bone-conduction (22.20 dB HL, SD 9.20-18.13 dB HL, SD 10.11, p < 0.0001) pure-tone average thresholds, were observed from last pre- to last postoperative audiometric data after stapedotomy. Comparison of first to last postoperative audiometric data revealed significant improvement in air-bone gap (10,74 dB HL, SD 7.20-7.70 dB HL, SD 5.691, p = 0.0002), as well as air conduction (31.63 dB HL, SD 12.30-26.29 dB HL, SD 10.24, p < 0.0001) and bone conduction (20.08 dB HL, SD 10.26-18.13 dB HL, SD 20.11, p = 0.011), at a mean postoperative follow-up time of 12.6 months, SD 9 months (2.4-37.3 months).</p><p><strong>Conclusion: </strong>Stapes footplate thickness in otosclerosis cases is not correlated with presurgical or postoperative hearing, nor with the incidence of postoperative complications. Stapedotomy can be performed safely regardless of the thickness of the stapes footplate.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-8"},"PeriodicalIF":1.6,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133157/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erin Harvey, Grace Callan, Neil Osafo, David Friedland, Michael S Harris, Jazzmyne Adams, Kristen Osinski, Ling Tong, Jake Luo
{"title":"Response to Oral Steroids for Sudden Sensorineural Hearing Loss: Considerations of Age, Time to Treatment, and Degree of Hearing Loss.","authors":"Erin Harvey, Grace Callan, Neil Osafo, David Friedland, Michael S Harris, Jazzmyne Adams, Kristen Osinski, Ling Tong, Jake Luo","doi":"10.1159/000545672","DOIUrl":"10.1159/000545672","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the study was to compare outcomes of oral steroids (OSs) to intratympanic (IT) steroids for treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) in a retrospective cohort study at a tertiary academic center.</p><p><strong>Methods: </strong>Patients diagnosed with ISSNHL receiving at least one course of OS between January 2009 and February 2022 were reviewed. OS patients were compared to a previously reported cohort of 74 patients who underwent IT treatment.</p><p><strong>Interventions: </strong>OS or IT steroid therapies are used for treating ISSNHL. Full, partial, or no recovery rates of hearing thresholds stratified by modality of treatment, age, degree of hearing loss, and time to initiation of treatment were measured.</p><p><strong>Results: </strong>There were 96 patients treated with OS and 74 patients treated with IT steroid. Full recovery was more frequent in patients who underwent OS therapy (43.8%) compared to IT therapy (25.68%, p = 0.017). For patients under 40 years old, full recovery rates were similar between OS (60.0%) and IT (61.5%). In patients over 40 years old, however, full recovery was seen in 40.7% of patients on OS and 18% for IT. Further, while those over 65 years had the worst rates of full recovery to IT steroid (<20%), this age group had a 50% full recovery rate with OSs. Additional factors correlating with response to both OS and IT treatments included degree of hearing loss and time to starting steroids.</p><p><strong>Conclusion: </strong>OS therapy was associated with greater likelihood of full recovery in all patient age groups compared to those treated with IT steroid alone, in combination with OS, or for salvage. A significant difference in response was seen in those over 65 years raising consideration of age stratification in decision-making for steroid modality in treatment of ISSNHL.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-9"},"PeriodicalIF":1.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamie A Schlacter, Christine Schremp, Allen Khudaverdyan, Emily R Spitzer, Susan B Waltzman
{"title":"The Effect of Comorbidities on Cochlear Implantation Outcomes in Adults Under 60.","authors":"Jamie A Schlacter, Christine Schremp, Allen Khudaverdyan, Emily R Spitzer, Susan B Waltzman","doi":"10.1159/000546569","DOIUrl":"https://doi.org/10.1159/000546569","url":null,"abstract":"<p><strong>Introduction: </strong>Prior studies have demonstrated that comorbid conditions can negatively impact cochlear implantation (CI) outcomes in elderly patients, but few have examined how comorbidities affect younger adult CI recipients. This study examines the relationship between comorbidities and CI outcomes in adults under 60 years old.</p><p><strong>Methods: </strong>We reviewed all CI recipients between 20 to 60 years old from 2015-2019 at a tertiary academic medical center. Patient data were collected including comorbidities, demographics, etiology, and length of deafness (LOD). Patients' Charlson Comorbidity Index (CCI) was calculated. The primary outcome was speech perception scores at 1-year on the consonant-nucleus-consonant (CNC) word test.</p><p><strong>Results: </strong>There were 118 patients who underwent CI (15% 20-29 years, 22% 30-39, 21% 40-49, 42% 50-60), averaging 1.8 comorbidities. Mean LOD was 19.7 years, and most etiologies were unknown (53.4%). 34% had no comorbidities, and the most frequent comorbidities were hypertension (14%), asthma (10%), anxiety (8%), acoustic neuroma (8%), and arthritis (7%). Comorbidity frequency was similar across ages, but cardiovascular comorbidities varied by patient decade (50-60 yrs: 41% vs. 20-49 yrs: 12-22%, p = 0.004). Compared to studies on elderly CI outcomes, our cohort had fewer comorbidities with reduced cardiac events and neurological conditions. We did not find differences in 1-year CNC scores or complications based on the number of comorbidities or any single comorbidity. However, there was a difference in individual improvement in CNC word scores by age group (p = 0.024). Patients' CCI did not correlate to post-op scores.</p><p><strong>Conclusion: </strong>Subjects showed improved speech understanding post-CI. The number and type of comorbidities were not meaningful predictors of 1-year speech perception scores, suggesting adult CI users under 60 years with comorbidities can expect comparable outcomes to those without comorbidities.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-17"},"PeriodicalIF":1.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adam C King, Abby Frazier, Krystal L Werfel, Emily Lund
{"title":"Balance Performance in Children Who Are Deaf and Hard of Hearing.","authors":"Adam C King, Abby Frazier, Krystal L Werfel, Emily Lund","doi":"10.1159/000545482","DOIUrl":"10.1159/000545482","url":null,"abstract":"<p><strong>Introduction: </strong>Hearing loss impacts children's ability to learn language and motor skills. This study examined the postural control differences between children who are deaf and hard of hearing (DHH) and typical hearing (TH), who differ in language and literacy performance, across diverse balance tasks.</p><p><strong>Methods: </strong>Thirty-three children between the ages of 6 and 13 performed a battery of balance tasks evaluating postural control and mobility. Twenty-six children were classified as DHH, while seven were TH children. Children participated in an extended battery of language and literacy measures, not unlike an intense academic day schedule. Assessments of postural control were conducted during a pre- and post-fatigue state.</p><p><strong>Results: </strong>Children who are DHH exhibited lower degrees of balance than TH children across the clinical, static, and dynamic balance evaluations.</p><p><strong>Conclusions: </strong>Our findings provide evidence of robust balance impairments for children who are DHH beyond standard clinical evaluations. Fatigue effects induced by testing had a greater impact on TH than DHH children, which may be related to chronic fatigue traits in DHH children. Overall, the results underscore the importance of characterizing balance impairments of children with hearing loss and determining the degree of impact on activities like academics.</p>","PeriodicalId":55432,"journal":{"name":"Audiology and Neuro-Otology","volume":" ","pages":"1-9"},"PeriodicalIF":1.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}