Biomedical and Environmental Sciences最新文献

{"title":"A Risk Assessment Model for Pancreatic Cancer Based on Cuproptosis-related Genes and Clinical Characteristics","authors":"Yi Kai CHEN , Si Qian WU , Wen Jun LIU","doi":"10.3967/bes2023.102","DOIUrl":"10.3967/bes2023.102","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 768-772"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10277375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observation of the Curative Effect of the Dexamethasone Vitreous Cavity Implant for the Treatment of Irvine-Gass Syndrome","authors":"Yu MAO ,&nbsp;Li Qin GAO ,&nbsp;Li Yun JIA ,&nbsp;Si Meng HOU ,&nbsp;Yuan Yuan XIAO ,&nbsp;Xi Wen JI ,&nbsp;Shuang WANG","doi":"10.3967/bes2023.084","DOIUrl":"10.3967/bes2023.084","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the clinical efficacy of dexamethasone vitreous cavity implants (Ozurdex) for the treatment of macular edema (Irvine-Gass Syndrome) after cataract surgery.</p></div><div><h3>Method</h3><p>Eight patients (eight eyes) with Irvine-Gass syndrome were enrolled for vitreous injections with Ozurdex. The patients included six men (six eyes) and two women (two eyes) with a mean age of 67.12 ± 11.92 years. Changes in the patients best-corrected visual acuity (BCVA), central macular thickness (CMT), and intraocular pressure were compared before and after treatment.</p></div><div><h3>Result</h3><p>The mean visual acuity BCVA of the patients was 0.81 ± 0.26 before implantation, which improved to 0.20 ± 0.12, 0.13 ± 0.09, and 0.15 ± 0.13 at 2 weeks, 1 month, and 3 months after implantation, respectively (<em>P</em> &lt; 0.001). The patient’s mean CMT before implantation was 703.00 ± 148.88 μm, and it reduced to 258.87 ± 37.40 μm, 236.25 ± 28.74 μm, and 278.00 ± 76.82 μm at 2 weeks, 1 month, and 3 months after implantation, respectively (<em>P</em> &lt; 0.001).</p></div><div><h3>Conclusion</h3><p>The dexamethasone vitreous cavity implant (Ozurdex) is a safe and effective treatment, which can effectively improve patient’s visual acuity and reduce macular edema associated with cataract surgery.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 725-731"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10288253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midday Napping, Nighttime Sleep, and Mortality: Prospective Cohort Evidence in China","authors":"Ke WANG ,&nbsp;Lan HU ,&nbsp;Lu WANG ,&nbsp;Hai Nan SHU ,&nbsp;Yi Ting WANG ,&nbsp;Yang YUAN ,&nbsp;Hong Ping CHENG ,&nbsp;Yun Quan ZHANG","doi":"10.3967/bes2023.073","DOIUrl":"10.3967/bes2023.073","url":null,"abstract":"<div><h3>Objective</h3><p>In developed countries, midday napping and nighttime sleep duration have been linked to long-term survival; however, little is known about such effects in less developed regions. Therefore, this study aimed to assess the associations of midday napping and nocturnal sleep with mortality in middle-aged and older Chinese adults.</p></div><div><h3>Methods</h3><p>A nationwide cohort of 15,524 adults aged ≥ 45 years was enrolled from 28 provincial regions across mainland China and followed up from 2011 to 2018, using data from the Chinese Health and Retirement Longitudinal Study. Midday napping and nighttime sleep duration were assessed using standardized questionnaires. Cox proportional hazards models with random intercepts for the surveyed provinces were used to estimate hazard ratios (<em>HR</em>s) of all-cause mortality, adjusting for sociodemographic characteristics, behavioral factors, and health status.</p></div><div><h3>Results</h3><p>A total of 1,745 deaths occurred during a median follow-up of 7.1 years, and the mean (standard deviation) age was 59 (10.1) years at baseline. Compared with non-nappers, over 60 min nappers had a higher risk of all-cause mortality [<em>HR</em>: 1.35, 95% confidence interval (<em>CI</em>): 1.17–1.56], while no significant associations were observed among &lt; 30 min nappers. Compared with sleep duration of 6–8 h/night, both short (&lt; 6 h) and long (≥ 8 h) sleep duration were significantly associated with increased mortality, with corresponding <em>HR</em> (95% <em>CI</em>) estimates of 1.21 (1.05–1.38) and 1.26 (1.10–1.44), respectively. We observed significant patterns for greater risks associated with longer nap duration, with a <em>P</em>_trend value &lt; 0.001 for all-cause mortality. No significant evidence of an additive interaction was identified between midday napping and nighttime sleep.</p></div><div><h3>Conclusion</h3><p>Long midday napping and inappropriate nighttime sleep were independently associated with an increased risk of all-cause mortality in middle-aged and older Chinese populations. Biological studies are needed to validate our findings and clarify the mechanisms underlying this association.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 702-714"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10288252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Report on Cardiovascular Health and Diseases in China 2022: an Updated Summary","authors":"The Writing Committee of the Report on Cardiovascular Health and Diseases in China","doi":"10.3967/bes2023.106","DOIUrl":"10.3967/bes2023.106","url":null,"abstract":"<div><p>In the past 30 years, the accessibility and quality index of medical care have made remarkable progress in China, ranking the first among middle-income countries. Many cardiovascular technologies are at or near the world’s leading level, and significant progress has been achieved in China solving the problem of “treatment difficulty” of cardiovascular diseases (CVD). However, due to the prevalence of unhealthy lifestyles among Chinese residents, a huge population with CVD risk factors, accelerated population aging, and other reasons, the incidence and mortality rate of CVD are still increasing, and the turning point of the decline in disease burden has not appeared yet in China. In terms of proportions of disease mortality among urban and rural residents, CVD still ranks the first. In 2020, CVD accounted for 48.00% and 45.86% of the causes of death in rural and urban areas, respectively; two out of every five deaths were due to CVD. It is estimated that the number of current CVD patients in China is around 330 million, including 13 million stroke, 11.39 million coronary heart disease, 8.9 million heart failure, 5 million pulmonary heart disease, 4.87 million atrial fibrillation, 2.5 million rheumatic heart disease, 2 million congenital heart disease, 45.3 million peripheral artery disease, and 245 million hypertension cases. China has entered a new stage of transformation from high-speed development to high-quality development, and the prevention and control of CVD in China should also shift from previous emphasis on scale growth to strategies focusing more on strategic and key technological development in order to curb the trend of increasing incidence and mortality rates of CVD.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 669-701"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10277368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Campylobacteriosis Outbreak Caused by One Asymptomatic Food Handler Carrier","authors":"Ai Xia YAN ,&nbsp;Gui Lan ZHOU ,&nbsp;Peng GAO ,&nbsp;Ying KANG ,&nbsp;Shou Fei LI ,&nbsp;Yuan Yuan WANG ,&nbsp;Feng Shuang WANG ,&nbsp;Hai Rui WANG ,&nbsp;Ying LI ,&nbsp;Mao Jun ZHANG","doi":"10.3967/bes2023.105","DOIUrl":"10.3967/bes2023.105","url":null,"abstract":"In August 2021, three students with diarrhea from the same school visited a local hospital in the S district of Beijing. An epidemic investigation showed that there were more students with diarrhea in the same school and they had one meal together. Campylobacter jejuni was isolated from both patients with diarrhea and asymptomatic food handlers; however, the latter also carried Campylobacter coli. Phylogenomic analysis showed that there was a campylobacteriosis outbreak among the students, and the asymptomatic food handler may have been the source of the infection. Routine inspection and surveillance for Campylobacter is needed for the food producing staff, particularly those cooking in the cafeteria in schools or other public food services.","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 779-782"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10277371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Gender Differences in Adolescent Dissociative Symptoms via A Structural Equation Model","authors":"Qing Lin CHENG ,&nbsp;Yuan Yuan DENG ,&nbsp;Gang ZHAO ,&nbsp;Jun Fang CHEN ,&nbsp;Li XIE ,&nbsp;Le WANG","doi":"10.3967/bes2023.103","DOIUrl":"https://doi.org/10.3967/bes2023.103","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 773-778"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49895809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Method for Folate Deficiency Screening","authors":"","doi":"10.3967/bes2023.108","DOIUrl":"10.3967/bes2023.108","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Page 784"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Method for Vitamin D Deficiency Screening","authors":"","doi":"10.3967/bes2023.109","DOIUrl":"10.3967/bes2023.109","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Page 785"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10650379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dual Role of Non-coding RNAs in the Development of Periodontitis","authors":"Xi XU ,&nbsp;Guang Ping LANG ,&nbsp;Zhong Lan CHEN ,&nbsp;Jing Le WANG ,&nbsp;Ying Ying HAN","doi":"10.3967/bes2023.079","DOIUrl":"10.3967/bes2023.079","url":null,"abstract":"This review aims to sum up how Non-coding RNAs (ncRNAs) regulate the development of periodontitis and provides a new perspective for understanding the pathogenesis of periodontitis. We explored the ncRNA's dual role in the development of periodontitis by summarizing evidence from previous in vivo and in vitro studies as well as clinical samples. In our review, the downregulation of 18 miRNAs, 22 lncRNAs and 10 circRNAs demonstrates protective roles in periodontitis. In contrast, the expression of other 11 miRNAs, 7 lncRNAs and 6 circRNAs are upregulated in periodontitis, which promote the progression of periodontitis. These dysregulated ncRNAs exert their protective or destructive roles by mainly influencing cell proliferation, differentiation and apoptosis via cross-talking with various molecules or signaling pathways. Our findings suggested which and how ncRNAs promote or delay the progression of periodontitis, which may greatly contribute to diagnose and therapy development of periodontitis based on ncRNAs in the future.","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 8","pages":"Pages 743-755"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10283964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metagenomic Analysis of Environmental Samples from Wildlife Rescue Station at Poyang Lake, China","authors":"Jia LIU ,&nbsp;Xi Yan LI ,&nbsp;Wen Tao SONG ,&nbsp;Xiao Xu ZENG ,&nbsp;Hui LI ,&nbsp;Lei YANG ,&nbsp;Da Yan WANG","doi":"10.3967/bes2023.087","DOIUrl":"10.3967/bes2023.087","url":null,"abstract":"<div><h3>Objective</h3><p>To improve the understanding of the virome and bacterial microbiome in the wildlife rescue station of Poyang Lake, China.</p></div><div><h3>Methods</h3><p>Ten smear samples were collected in March 2019 Metagenomic sequencing was performed to delineate bacterial and viral diversity. Taxonomic analysis was performed using the Kraken2 and Bracken methods. A maximum-likelihood tree was constructed based on the RNA-dependent RNA polymerase (RdRp) region of picornavirus.</p></div><div><h3>Results</h3><p>We identified 363 bacterial and 6 viral families. A significant difference in microbial and viral abundance was found between samples S01–S09 and S10. In S01–S09, members of <em>Flavobacteriia</em> and <em>Gammaproteobacteria</em> were the most prevalent, while in S10, the most prevalent bacteria class was <em>Actinomycetia</em>. Among S01–S09, members of <em>Myoviridae</em> and <em>Herelleviridae</em> were the most prevalent, while the dominant virus family of S10 was <em>Picornaviridae</em>. The full genome of the pigeon mesivirus-like virus (NC-BM-233) was recovered from S10 and contained an open reading frame of 8,124 nt. It showed the best hit to the pigeon mesivirus 2 polyprotein, with 84.10% amino acid identity. Phylogenetic analysis showed that RdRp clustered into <em>Megrivirus B</em>.</p></div><div><h3>Conclusion</h3><p>This study provides an initial assessment of the bacteria and viruses in the cage-smeared samples, broadens our knowledge of viral and bacterial diversity, and is a way to discover potential pathogens in wild birds</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 595-603"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}