Biomedical and Environmental Sciences最新文献

{"title":"Neutralizing Antibody Responses against Five SARS-CoV-2 Variants and T Lymphocyte Change after Vaccine Breakthrough Infections from the SARS-CoV-2 Omicron BA.1 Variant in Tianjin, China: A Prospective Study","authors":"Ying ZHANG ,&nbsp;Jiang Wen QU ,&nbsp;Min Na ZHENG ,&nbsp;Ya Xing DING ,&nbsp;Wei CHEN ,&nbsp;Shao Dong YE ,&nbsp;Xiao Yan LI ,&nbsp;Yan Kun LI ,&nbsp;Ying LIU ,&nbsp;Di ZHU ,&nbsp;Can Rui JIN ,&nbsp;LIN WANG ,&nbsp;Jin Ye YANG ,&nbsp;Yu ZHAI ,&nbsp;Er Qiang WANG ,&nbsp;Xing MENG","doi":"10.3967/bes2023.047","DOIUrl":"10.3967/bes2023.047","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate whether Omicron BA.1 breakthrough infection after receiving the SARS-CoV-2 vaccine could create a strong immunity barrier.</p></div><div><h3>Methods</h3><p>Blood samples were collected at two different time points from 124 Omicron BA.1 breakthrough infected patients and 124 controls matched for age, gender, and vaccination profile. Live virus-neutralizing antibodies against five SARS-CoV-2 variants, including WT, Gamma, Beta, Delta, and Omicron BA.1, and T-lymphocyte lymphocyte counts in both groups were measured and statistically analyzed.</p></div><div><h3>Results</h3><p>The neutralizing antibody titers against five different variants of SARS-CoV-2 were significantly increased in the vaccinated population infected with the Omicron BA.1 variant at 3 months after infection, but mainly increased the antibody level against the WT strain, and the antibody against the Omicron strain was the lowest. The neutralizing antibody level decreased rapidly 6 months after infection. The T-lymphocyte cell counts of patients with mild and moderate disease recovered at 3 months and completely returned to the normal state at 6 months.</p></div><div><h3>Conclusion</h3><p>Omicron BA.1 breakthrough infection mainly evoked humoral immune memory in the original strain after vaccination and hardly produced neutralizing antibodies specific to Omicron BA.1. Neutralizing antibodies against the different strains declined rapidly and showed features similar to those of influenza. Thus, T-lymphocytes may play an important role in recovery.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 614-624"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Breastfeeding Duration with Body Composition in Children Aged 3–5 Years","authors":"Li Ping SHEN ,&nbsp;Xue Hong PANG ,&nbsp;Jie WANG ,&nbsp;Yi Fan DUAN ,&nbsp;Qian ZHANG ,&nbsp;Yu Ying WANG ,&nbsp;Bo Wen CHEN ,&nbsp;Tao XU ,&nbsp;Wen Hua ZHAO ,&nbsp;Zhen Yu YANG","doi":"10.3967/bes2023.085","DOIUrl":"10.3967/bes2023.085","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to assess the relationship between the body composition of children aged 3–5 years and breastfeeding status and duration.</p></div><div><h3>Methods</h3><p>The study was conducted using data from the National Nutrition and Health Systematic Survey for children 0–17 years of age in China (CNHSC), a nationwide cross-sectional study. Breastfeeding information and potential confounders were collected using standardized questionnaires administered through face-to-face interviews. The body composition of preschool children was measured using bioelectrical impedance analysis. A multivariate linear regression model was used to assess the relationship between breastfeeding duration and body composition after adjusting for potential confounders.</p></div><div><h3>Results</h3><p>In total, 2,008 participants were included in the study. Of these, 89.2% were ever breastfed and the median duration of breastfeeding was 12 months (IQR 7–15 months). Among children aged 3 years, the height-for-age <em>Z</em>-score (HAZ) for the ever breastfed group was lower than that for never breastfed group (0.12 <em>vs</em>. 0.42, <em>P</em> = 0.043). In addition, the weight-for-age <em>Z</em>-score (WAZ) of the ever breastfed group was lower than that of the never breastfed group (0.31 <em>vs</em>. 0.65, <em>P</em> = 0.026), and the WAZ was lower in children aged 4 years who breastfed between 12 and 23 months than in those who never breastfed. Compared to the formula-fed children, the fat-free mass of breastfed infants was higher for children aged 3 years (12.84 kg <em>vs</em>. 12.52 kg, <em>P</em> = 0.015) and lower for those aged 4 years (14.31 kg <em>vs</em>. 14.64 kg, <em>P</em> = 0.048), but no difference was detected for children aged 5 years (16.40 kg <em>vs</em>. 16.42 kg, <em>P</em> = 0.910) after adjusting for potential confounders. No significant difference was detected in the weight-for-height <em>Z</em>-score (WHZ), body mass index (BMI)-for-age <em>Z</em>-score (BAZ), fat-free mass index, and body fat indicators in the ever breastfed and never breastfed groups and among various breastfeeding duration groups for children aged 3–5 years.</p></div><div><h3>Conclusion</h3><p>No obvious associations were detected between breastfeeding duration, BMI, and fat mass indicators. Future prospective studies should explore the relationship between breastfeeding status and fat-free mass.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 569-584"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood Sexual Abuse and Quality of Life in Chinese Undergraduates: the Mediating Role of Resilience","authors":"Xue WEN ,&nbsp;Yuan LI ,&nbsp;Yong Han LI ,&nbsp;Jun Jie CHANG ,&nbsp;Meng Yuan YUAN ,&nbsp;Lei Lei CAO ,&nbsp;Shao Jie WANG ,&nbsp;Pu Yu SU ,&nbsp;Geng Fu WANG","doi":"10.3967/bes2023.095","DOIUrl":"10.3967/bes2023.095","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 658-662"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Manifestations and Surgical Outcomes of Primary Rhegmatogenous Retinal Detachment in Patients < 30 Years of Age with High Myopia","authors":"Xin WANG ,&nbsp;Ting ZHANG ,&nbsp;Wen Yi TANG ,&nbsp;Xin HUANG","doi":"10.3967/bes2023.092","DOIUrl":"10.3967/bes2023.092","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 644-648"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Microdroplet Digital PCR Assays with Real-time Fluorescence Quantitative PCR for Clostridioides difficile Detection","authors":"Cai Hong YIN ,&nbsp;Zhan Yun SONG ,&nbsp;Xing Xing LIU ,&nbsp;Xiao Mu WANG ,&nbsp;Ying WANG ,&nbsp;Cheng Cheng GAO ,&nbsp;Xiu Ling SONG ,&nbsp;Xin FENG","doi":"10.3967/bes2023.094","DOIUrl":"https://doi.org/10.3967/bes2023.094","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 653-657"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49838908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement of the Thermic Effect of Food in a Chinese Mixed Diet in Young People","authors":"Ying TIAN ,&nbsp;Hong Peng CAO ,&nbsp;Yu Ping HUAN ,&nbsp;Jia Wei GONG ,&nbsp;Kai Hua YUAN ,&nbsp;Wen Zhuo CHEN ,&nbsp;Jing HU ,&nbsp;Yu Fei SHI","doi":"10.3967/bes2023.086","DOIUrl":"10.3967/bes2023.086","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the thermic effect of food (TEF) in a Chinese mixed diet in young people.</p></div><div><h3>Methods</h3><p>During the study, the participants were weighed and examined for body composition every morning. The total energy expenditure (TEE) of the participants was measured by the doubly labelled water method for 7 days, and during this period, basal energy expenditure was measured by indirect calorimetry and physical activity energy expenditure was measured by an accelerometer. The value obtained by subtracting basal energy expenditure and physical activity energy expenditure from TEE was used to calculate TEF.</p></div><div><h3>Results</h3><p>Twenty healthy young students (18–30 years; 10 male) participated in the study. The energy intake of the participants was not significantly different from the Chinese Dietary Reference Intake of energy (<em>P</em> &gt; 0.05). The percentage of energy from protein, fat and carbohydrate were all in the normal range. The intakes of fruits, milk and dietary fiber of the participants were significantly lower than those in the Chinese Dietary Guidelines (<em>P</em> &lt; 0.05). There was no significant difference in the body weight of the participants during the experiment (<em>P</em> &gt; 0.05). When adjusted for body weight, there was no significant difference in either TEE or basal energy expenditure between the male and female participants (<em>P</em> &gt; 0.05). In addition, there was no significant difference in physical activity energy expenditure and TEF between the male and female participants (<em>P</em> &gt; 0.05). The percentage of TEF in TEE was 8.73%.</p></div><div><h3>Conclusion</h3><p>The percentage of TEF in TEE in a Chinese mixed diet in young people was significantly lower than 10% (<em>P</em> &lt; 0.001). A value of 10% is usually considered to be the TEF in mixed diets as a percentage of TEE.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 585-594"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth Standard for Children Under 7 Years of Age","authors":"","doi":"10.3967/bes2023.096","DOIUrl":"10.3967/bes2023.096","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 663-664"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Standard for Healthy Chinese Older Adults","authors":"","doi":"10.3967/bes2023.098","DOIUrl":"10.3967/bes2023.098","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 666-667"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rapid Trace Analysis of GBS using the Specific Spectral Absorption of Chromogenic Culture Media","authors":"Yang CHEN ,&nbsp;Yan Yan ZHANG ,&nbsp;Yao Gen SHU","doi":"10.3967/bes2023.093","DOIUrl":"10.3967/bes2023.093","url":null,"abstract":"","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 649-652"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9923862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic and Phenotypic Variation of Campylobacter jejuni NCTC11168 Caused by flhA Mutation during Laboratory Passage","authors":"Xiao Li CHEN ,&nbsp;Hao LIANG ,&nbsp;Peng Bo GUO ,&nbsp;Yi Xin GU ,&nbsp;Jia Qi WANG ,&nbsp;Hai Rui WANG ,&nbsp;Gui Lan ZHOU ,&nbsp;Zhu Jun SHAO ,&nbsp;Jian Zhong ZHANG ,&nbsp;Mao Jun ZHANG","doi":"10.3967/bes2023.088","DOIUrl":"https://doi.org/10.3967/bes2023.088","url":null,"abstract":"<div><h3>Objective</h3><p><em>Campylobacter jejuni</em> NCTC11168 is commonly used as a standard strain for flagellar biosynthesis research. In this report, two distinguished phenotypic isolates (CJ1Z, <em>flhA</em> mutant strain, lawn; CJ2S, <em>flhA</em> complemented strain, normal colony) appeared during laboratory passages for NCTC11168.</p></div><div><h3>Methods</h3><p>Phenotypic assessments, including motility plates, transmission electron microscopy, biofilm formation assay, autoagglutination assay, and genome re-sequencing for these two isolates (CJ1Z, <em>flhA</em> mutant strain; CJ2S, <em>flhA</em> complemented strain) were carried out in this study.</p></div><div><h3>Results</h3><p>Transmission electron microscopy revealed that the flagellum was lost in CJ1Z. Phenotypic assessments and genome sequencing of the two isolates were performed in this study. The capacity for biofilm formation, colony auto-agglutination, and isolate motility was reduced in the mutant CJ1Z. Comparative genomic analysis indicated a unique native nucleotide insertion in flhA (nt, 2154) that caused the I719Y and I720Y mutations and early truncation in flhA.</p></div><div><h3>Conclusion</h3><p>FlhA has been found to influence the expression of flagella in <em>C. jejuni</em>. To the best of our knowledge, this is the first study to describe the function of the C-terminal of this protein.</p></div>","PeriodicalId":55364,"journal":{"name":"Biomedical and Environmental Sciences","volume":"36 7","pages":"Pages 604-613"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49838907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}