Brazilian Journal of Biology最新文献

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Myxobiota of the Silvânia National Forest: list of species with additions to Cerrado and Brazil. silv<e:1>尼亚国家森林的黏菌门:塞拉多和巴西新增的物种列表。
Brazilian Journal of Biology Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.286590
L A Toschi, I C Moreira, L Leonardo-Silva, S Xavier-Santos
{"title":"Myxobiota of the Silvânia National Forest: list of species with additions to Cerrado and Brazil.","authors":"L A Toschi, I C Moreira, L Leonardo-Silva, S Xavier-Santos","doi":"10.1590/1519-6984.286590","DOIUrl":"https://doi.org/10.1590/1519-6984.286590","url":null,"abstract":"<p><p>Aiming to contribute information on the diversity of Myxomycetes in Brazilian Savanna (Cerrado biome) areas, the species of myxomycetes present in Silvânia National Forest, in the state of Goiás were inventoried. This inventory is made up of collections carried out 17 ago in the area, including collections by active search and moist chamber sampling. Samples of fruiting bodies were deposited in the HUEG Fungarium. Were recorded 55 species, 27 genera, 11 families and 8 orders. The most represented orders were Trichiales and Stemonitales, each representing 28% of the species, followed by Physarales with 23%, Cribrariales with 7%, Ceratiomyxales, Liceales and Reticulariales with 4% and finally, Echinosteliales with 2%. Three species (Colloderma oculatum, Polyschismium chailletii and Trichia flavicoma) are being reported for the first time for Brazil and eight (Ceratiomyxa morchella, Licea castanea, Licea minima, Lycogala conicum, Paradiacheopsis longipes, Stemonitopsis gracilis, Stemonitopsis hyperopta and Stemonitis virginiensis) for Cerrado biome. Therefore, this study adds important data for the knowledge of the myxobiota, not only for the biome, but also for Brazil.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e286590"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation and optimization of cellulase producing bacteria from Hon Giao pygmy forest soil in Vietnam. 越南洪桥矮林土壤纤维素酶产菌的分离与优化。
Brazilian Journal of Biology Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.291079
T T A Le
{"title":"Isolation and optimization of cellulase producing bacteria from Hon Giao pygmy forest soil in Vietnam.","authors":"T T A Le","doi":"10.1590/1519-6984.291079","DOIUrl":"https://doi.org/10.1590/1519-6984.291079","url":null,"abstract":"<p><p>The cellulase producing bacteria were isolated from the soil of a pygmy forest in Vietnam. Out of 13 cellulase producing isolates, two strains exhibited the maximum clearance zone and cellulase producing capacity and were identified as Bacillus sp. D2T3-7 and Bacillus velezensis strain D3T1-18 based on morphological; cultural, biochemical and phylogenetic analysis of 16S rRNA. The optimal culture conditions including pH, temperature, carbon sources, and nitrogen sources for cellulase activity were investigated. The maximal cellulase activity were obtained at pH of 5.5 of incubation at 35oC with carboxymethyl cellulase as the sole carbon source, and ammonium sulfate as sole nitrogen source for both isolates. The results of the study suggest bacteria isolated from pigmy forests have the potential for degradation of cellulose rich pollutants in different environmental matrices such as agricultural waste, paper sludge, textile fibers.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e291079"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association-based rubber trading system as an agricultural development innovation. 以协会为基础的橡胶交易制度作为农业发展的创新。
Brazilian Journal of Biology Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.294584
M Sasmi, A Agustar, I W Syarfi, Hasnah
{"title":"Association-based rubber trading system as an agricultural development innovation.","authors":"M Sasmi, A Agustar, I W Syarfi, Hasnah","doi":"10.1590/1519-6984.294584","DOIUrl":"10.1590/1519-6984.294584","url":null,"abstract":"<p><p>Rubber is a necessary commodity produced by the agricultural sector in Kuantan Singingi Regency, but its role in improving welfare is not yet significant. Marketing agricultural products is still a problem because traders set prices unilaterally. Agricultural institutions solve farmers' problems, especially in the trading system. This research aims to build an association-based rubber trading system as an agricultural development innovation. This research uses a qualitative approach. Data and data sources were obtained from key informants, and triangulation was carried out. Nine informants were selected using snowball sampling. Data was collected through in-depth interviews using interview guides, observation, and documentation. Data was analyzed descriptively and qualitatively. The research results show that the existence of the Kuantan Singingi Rubber Farmers Association (APKARKUSI) can play a role in distributing rubber to the Crumb Rubber Factory effectively and efficiently, can increase prices, can play a role in setting prices, can increase farmers' bargaining power, stabilize prices at the farmer level, guarantee quality according to buyers' needs, and can convey broad and transparent price information.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e294584"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring 5,7-dimethoxyflavone from Piper ornatum as a novel anti-breast cancer candidate: insights from in silico analysis. 从花椒中提取的5,7-二甲氧基黄酮作为一种新的抗乳腺癌候选药物:来自硅分析的见解。
Brazilian Journal of Biology Pub Date : 2025-06-02 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.288642
A U Rohmatika, T Demircan, A K M Jamil, F R P Dewi
{"title":"Exploring 5,7-dimethoxyflavone from Piper ornatum as a novel anti-breast cancer candidate: insights from in silico analysis.","authors":"A U Rohmatika, T Demircan, A K M Jamil, F R P Dewi","doi":"10.1590/1519-6984.288642","DOIUrl":"https://doi.org/10.1590/1519-6984.288642","url":null,"abstract":"<p><p>This study investigates the potential of the compound 5,7-dimethoxyflavone (5,7-DMF) found in Piper ornatum as an anti-breast cancer agent using an in silico approach. The study targeted three major mechanisms involved in breast cancer progression: the ability of 5,7-DMF to inhibit kinase activity, act as a competitive inhibitor of cyclooxygenase 2 (COX-2) and nitric oxide synthase 2 (NOS2). This was investigated through molecular simulation by assessing drug-likeness, toxicity, membrane permeability, bioactivity, specific docking with AutoDock Vina integrated with PyRx 8.0, as well as molecular dynamics simulation using CABS-flex 2.0. Molecular docking results showed that 5,7-DMF has a high binding affinity towards the COX-2 target and inhibits kinase activity. This study also revealed significant interactions between 5,7-DMF and the COX-2 active site, supporting its potential as an anti-breast cancer agent. These results provide a solid basis for the further development of 5,7-DMF as a potential drug candidate against breast cancer.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e288642"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Susceptibility of Pitaya genotypes to Meloidogyne incognita and M. javanica: implications for nematode management in Brazil. 火龙果基因型对未知螺线虫和爪哇螺线虫的易感性:对巴西线虫管理的意义。
Brazilian Journal of Biology Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.291703
L T Bombonato, R J Ferreira, E M Silva, A C Araujo-Filho, D D Nascimento, D B Diniz, R A Andrade, J A A Silva, H C de la Cruz, G H S Nunes, P L M Soares
{"title":"Susceptibility of Pitaya genotypes to Meloidogyne incognita and M. javanica: implications for nematode management in Brazil.","authors":"L T Bombonato, R J Ferreira, E M Silva, A C Araujo-Filho, D D Nascimento, D B Diniz, R A Andrade, J A A Silva, H C de la Cruz, G H S Nunes, P L M Soares","doi":"10.1590/1519-6984.291703","DOIUrl":"https://doi.org/10.1590/1519-6984.291703","url":null,"abstract":"<p><p>Pitaya (Selenicereus spp., Cactaceae) has gained popularity among fruit consumers due to its distinctive flavor, shape, color, as well as vitamin C and B contents. However, recent studies have reported pitaya as a host for economically important nematodes of the genus Meloidogyne. These nematodes exhibit a wide host range and are distributed across Brazil. This study assessed the susceptibility of six pitaya genotypes (S. undatus, S. polyrhizus, S. undatus subsp. lithocarpus, S. megalanthus, S. setaceus, and S. megalanthus × S. costaricensis 'Orange') to Meloidogyne incognita and M. javanica. The experiment was conducted in a completely randomized design with 20 replicates. The total numbers of eggs and second-stage juveniles (J2), as well as eggs and J2 per gram of root, were used to calculate the reproduction factor and reproduction index. Plant assessments included measurements of shoot and root fresh weights. The pitaya genotypes S. undatus, S. polyrhizus, S. undatus subsp. lithocarpus, S. megalanthus, S. setaceus, and S. megalanthus × S. costaricensis 'Orange' were classified as susceptible to M. incognita and M. javanica, as their reproduction factors exceeded 1. Further studies are necessary to identify pitaya genotypes resistant to plant-parasitic nematodes, as genetic resistance remains one of the most effective and cost-efficient strategies for nematode control in agricultural systems.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e291703"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Escherichia coli isolates in meat products: a systematic review. 肉制品中大肠杆菌分离株的流行:一项系统综述。
Brazilian Journal of Biology Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.292127
L Brito-Junior, H C Brito, M M Simões, J H A Farias, B Santos, F M C Marques, M A A Medeiros, M S Alves, C T Pereira, A F Diniz, V L R Vilela, D R Silva, A Oliveira-Filho
{"title":"Prevalence of Escherichia coli isolates in meat products: a systematic review.","authors":"L Brito-Junior, H C Brito, M M Simões, J H A Farias, B Santos, F M C Marques, M A A Medeiros, M S Alves, C T Pereira, A F Diniz, V L R Vilela, D R Silva, A Oliveira-Filho","doi":"10.1590/1519-6984.292127","DOIUrl":"https://doi.org/10.1590/1519-6984.292127","url":null,"abstract":"<p><p>The presence of microorganisms in food, especially meat, requires strict monitoring to prevent disease and contamination. Among the most relevant bacteria is Escherichia coli, which is widely associated with meat products. The aim of this study was to carry out a systematic literature review focused on the detection of Escherichia coli in meat. The review covered studies published between 2021 and 2024, in English, Spanish and Portuguese. Data collection was carried out through CAPES Electronic Journals, using three databases: Scopus, Virtual Health Library (BIREME) and Web of Science. Initially, 149 articles were identified, of which 34 were excluded due to duplication in the databases. Thus, 115 articles were selected for the reading of titles and abstracts, resulting in the exclusion of 79 articles that did not meet the inclusion criteria. This left 36 articles for eligibility assessment, 20 of which were excluded because they did not specifically detect E. coli in meat. Finally, 16 articles were included in the review. The results reveal a significant prevalence of E. coli in meat products, highlighting the need for strict sanitary control practices throughout the production chain, from animal husbandry to final meat processing. The analysis also indicates that chicken and beef have a higher incidence of E. coli compared to pork and fish, underlining the importance of specific monitoring for these types of meat.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e292127"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the mating process of Mahanarva spectabilis (Hemiptera: Cercopidae) mediated by chemical signals? Mahanarva spectabilis(半翅目:蠓科)的交配过程是否由化学信号介导?
Brazilian Journal of Biology Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.291452
M G Fonseca, M O C Mendonça, A M Auad
{"title":"Is the mating process of Mahanarva spectabilis (Hemiptera: Cercopidae) mediated by chemical signals?","authors":"M G Fonseca, M O C Mendonça, A M Auad","doi":"10.1590/1519-6984.291452","DOIUrl":"https://doi.org/10.1590/1519-6984.291452","url":null,"abstract":"<p><p>Mahanarva spectabilis (Distant) is an important pasture pest in Brazil and represents an obstacle to forage production. Elucidating the chemical signals involved in the communication of this species is essential for finding new control alternatives. Therefore, the aim of this study was to determine whether chemical signals are involved in the mating process of M. spectabilis. In the first trial, the insect's behavior was evaluated in cages with male: female ratios of 4:1 and 1:4. As soon as copulation began, the behavior of males or females around the copulating couple was recorded. In subsequent trials, the olfactory responses of males and females of M. spectabilis were evaluated in a Y-shaped olfactometer for volatiles released by males, females and mating pairs. At a male: female ratio of 4:1, there were significantly more touches by the other males of the copulating couple. The number of individuals attached to the copulating couple and the copulation time did not differ significantly in relation to the male: female ratio used. The attractiveness of males to copulating pairs was also observed in the olfactometry test, in which males were significantly attracted only to copulating pairs and to the extract of copulating pairs. The females showed no olfactory attraction to any of the odor sources offered. This shows that chemical signals are involved in the mating process of M. spectabilis.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e291452"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Main chemical constituents and pharmacological activities of Dimorphandra spp. 双地菊属植物的主要化学成分及药理活性。
Brazilian Journal of Biology Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.294574
W A Silva, I L Soares, K C Mousinho, T G Araújo, G M Menezes, I B M F Alencar, G S Procopio, K M R Araújo, R B Vasconcelos, R B V Marinho, T M Wanderley, J C Costa, M A M Bandeira
{"title":"Main chemical constituents and pharmacological activities of Dimorphandra spp.","authors":"W A Silva, I L Soares, K C Mousinho, T G Araújo, G M Menezes, I B M F Alencar, G S Procopio, K M R Araújo, R B Vasconcelos, R B V Marinho, T M Wanderley, J C Costa, M A M Bandeira","doi":"10.1590/1519-6984.294574","DOIUrl":"https://doi.org/10.1590/1519-6984.294574","url":null,"abstract":"<p><p>In the pharmaceutical industry, the fruits of the fava d'anta are used to extract quercetin and rutin, which are the basis for the production of medicines that work to treat varicose veins, hemorrhoids, circulatory system disorders and a variety of other conditions. The aim of this article is to carry out a comprehensive review of the chemical constitution and pharmacology of fava d'anta. This is an integrative review using the following databases: Embase, SciElo, LILACS, CAPES Periodicals and Medline, with the search expression \"Dimorphandra gardneriana\" OR \"Dimorphandra mollis\". Studies were selected without any restrictions on language or time of publication, in order to conduct the most comprehensive search possible. A total of 278 articles were identified, of which 72 were viewed on Embase, 31 on Scielo, 19 on LILACS, 114 on CAPES and 42 on Medline. After reviewing the titles, abstracts and removing duplicates, 13 articles were obtained for full text analysis. The studies analyzed showed various pharmacological activities of the compounds extracted from the D. mollis and D. gardneriana species, including antioxidant, anti-inflammatory, neuroprotective, antiviral and lipid metabolism modulating properties. Thus, the presence of the flavonoids rutin and quercetin reinforces the potential of these species for therapeutic applications.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e294574"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of liquid swine effluent on the initial growth of forage corn under greenhouse conditions. 温室条件下猪液对饲用玉米初期生长的影响。
Brazilian Journal of Biology Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.290232
M Y Peña Caurino, D B Luis Olivas, T A Gambini de la Cruz, E Mendoza Nieto, B Fardim Christo, S Contreras-Liza
{"title":"Effect of liquid swine effluent on the initial growth of forage corn under greenhouse conditions.","authors":"M Y Peña Caurino, D B Luis Olivas, T A Gambini de la Cruz, E Mendoza Nieto, B Fardim Christo, S Contreras-Liza","doi":"10.1590/1519-6984.290232","DOIUrl":"https://doi.org/10.1590/1519-6984.290232","url":null,"abstract":"<p><p>The use of organic effluents from livestock farming as biofertilizers for agriculture represents a viable solution for the management of swine waste. The research aimed to evaluate the effect of swine liquid effluent on the growth of hybrid corn for forage purposes. A pot experiment was designed to determine the effect of liquid effluent applications of treatments 21 days after planting. The biofertilizer treatments applied to the irrigation water in the pots were 0.00 (control), 9.45, 18.90, 28.35, 37.80 and 47.25 m3 ha-1. Applications of 37.80 and 47.25 m3 ha-1 improved stem diameter, foliage, and total fresh weight. For root fresh weight and root volume, the highest values occurred with applications of 18.90 to 47.25 m3 ha-1. The nutrient content (N, P, K) of corn treated with swine liquid effluent showed an incremental trend in foliage and roots, as well as the absorption of macronutrients due to the effect of the treatments. Liquid swine effluent showed a promising role as an organic fertilizer for the cultivation of maize for forage purposes, promoting higher biomass production and macronutrient uptake.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e290232"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sauropus androgynus chlorophyll ameliorates the hazardous effect of sodium nitrite-induced oxidative stress in adult female rats. 雌雄同体蜥蜴叶绿素改善亚硝酸钠诱导的成年雌性大鼠氧化应激的危害作用。
Brazilian Journal of Biology Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1590/1519-6984.292058
S Suparmi, M Fasitasari, F Latifah, L Ifroza, N H Taufiqurrokhim, L A Lestanu, D Irmadhani, D P A S Wahyudi, N Rustanti
{"title":"Sauropus androgynus chlorophyll ameliorates the hazardous effect of sodium nitrite-induced oxidative stress in adult female rats.","authors":"S Suparmi, M Fasitasari, F Latifah, L Ifroza, N H Taufiqurrokhim, L A Lestanu, D Irmadhani, D P A S Wahyudi, N Rustanti","doi":"10.1590/1519-6984.292058","DOIUrl":"https://doi.org/10.1590/1519-6984.292058","url":null,"abstract":"<p><p>Sodium nitrate (NaNO2), frequently utilized as a food ingredient for colour enhancement and meat preservation, has been shown to induce oxidative stress and cause anaemia. This study evaluated the ameliorative effect of tablets from the chlorophyll of S. androgynus (L) Merr leaves (TCSA) in NaNO2-induced rats. Thirty-six adult female Wistar rats were randomly assigned to 6 groups: control group, NaNO2 group (50 mg/kg BW), NaNO2+ TCSA-1 (50 mg/kg NaNO2 and 0.016 mg/kg BW TCSA), NaNO2+ TCSA-10 (50 mg/kg NaNO2 and 0.16 mg/kg BW TCSA), NaNO2+ TCSA-100 (50 mg/kg NaNO2 and 1,6 mg/kg BW TCSA), and NaNO2+ Fe (positive control group, 50 mg/kg NaNO2 and iron/ Fe supplement). Over 30 days, the haematological and liver function were assessed from blood samples. Exposure to NaNO2 resulted in significant reductions in packed cell volume (PCV), haemoglobin (Hb) concentration, and red blood cell (RBC) count, alongside elevated levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine, urea, and gamma-glutamyl transferase (γ-GT). TCSA had a therapeutic benefit in NaNO2-induced rats comparable to iron supplementation. The antioxidant properties of chlorophyll in the tablets markedly reduce the oxidative damage caused by NaNO2. Further studies are necessary to comprehensively analyze the molecular evaluations of the biological activities of tablets from S. androgynus chlorophyll.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e292058"},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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