Brazilian Journal of Biology最新文献

{"title":"Conservation challenges of Birds of Paradise in Papua, Indonesia: a systematic literature review.","authors":"E K Raunsay, R E Rehiara, W Nurcholis","doi":"10.1590/1519-6984.289477","DOIUrl":"https://doi.org/10.1590/1519-6984.289477","url":null,"abstract":"<p><p>Indonesia, recognized as the world's second-largest mega-biodiversity country, is home to a remarkable variety of endemic species, including the iconic Birds of Paradise. Despite its rich biodiversity, the population of Birds of Paradise in Papua, Indonesia, is critically threatened by factors such as habitat loss, hunting, and exploitation. This systematic literature review aims to identify and synthesize the key reasons behind the conservation of these birds and evaluate current conservation strategies. Utilizing the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, 354 articles were screened from databases, including Scopus, Web of Science, and Google Scholar, with 39 articles meeting the inclusion criteria. The review highlights that habitat destruction, introduced species, and unsustainable hunting practices are the primary threats to these species. The novelty of this study lies in its comprehensive synthesis of biological, ecological, and socio-cultural factors influencing the conservation of Birds of Paradise in Papua, as well as the evaluation of advanced genetic technologies as potential conservation strategies. The findings underscore the urgent need for enhanced conservation measures, including the development of advanced genetic technologies and community-driven efforts, to preserve the unique biodiversity of Papua's Birds of Paradise.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e289477"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identity of Crassostrea praia () and other oysters from Rio Grande do Sul, Brazil.","authors":"J P R Ferreira, C H A M Gomes, T B Freire, B M S Scaranto, F L Zacchi, C M R Melo","doi":"10.1590/1519-6984.291323","DOIUrl":"https://doi.org/10.1590/1519-6984.291323","url":null,"abstract":"<p><p>The study aimed to identify species of the genus Crassostrea from Rio Grande do Sul and to trace the identity of C. praia, a species recognized under conchological or distributive precepts of native oyster species occurring in an ecological gradient beyond mangrove vegetation. To achieve this, oysters were collected in the southernmost region of Brazil (RS) for morphological and molecular identification of C. praia. The specimens were subjected to a diagnostic PCR-RFLP analysis and sequencing of the mitochondrial 16S rDNA gene. Based on the molecular identity of the specimens, a comparative anatomical assessment was made, involving the sizes of the mantle and the labial palps, the shapes of the accessory heart, heart, and anus, and pattern of the tentacles on the edge of the mantle. The molecular results showed the presence of two species in RS: C. rhizophorae and C. gasar, with the latter being a new occurrence for regions beyond mangrove vegetation. C. praia proved to be conspecific with C. rhizophorae, being its synonym. Anatomical data related to the species are plastic and incapable of generating specific criteria for identification between C. gasar and C. rhizophorae. Regarding the shell criteria used to promote the construction of the C. praia entity, they are deeply related to environmental conditions and the effect of population density on its conchological characters, since its molecular identity indicates that this species is synonymous with C. rhizophorae.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e291323"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral anticancer promising of hexadecanoic acid through melecular interaction to nuclear factor-kappa-B p65/RELA and tumor suppressor-p53.","authors":"N Mufidah, K Muzari, H S Budi, R Indrawati, S Anitasari, Y K Shen, U Umarudin","doi":"10.1590/1519-6984.287760","DOIUrl":"https://doi.org/10.1590/1519-6984.287760","url":null,"abstract":"<p><p>Ambonese banana stem extract (Musa paradisiaca var. sapientum (L.) Kuntze) has been proven to contain the active compound Hexadecanoic acid (Hexa) which can suppress the growth of cancer cells through the apoptosis process. The aims to determine HA interaction to nuclear factor-kappa-B p65/RELA and tumor suppressor-p53 for the development of oral anticancer drugs through molecular docking. In silico molecular docking study carried out include prediction of activity spectra of substances (PASS), drug-likeness analysis based on the lipinski rule of five principles, absorption, distribution, metabolism, excretion, and toxicity (ADMET) study, molecular docking and Hexa bond visualization (CID: 985), along with the positive control comparison 5-fluorouracil (Fluo) (CID: 3385) and the derivative compound 9-octadecenoic acid (Octa) (CID: 445639) which bind to the proteins target RELA (PDB ID: 6NV2) and p53 (PDB ID: 2OCJ). The Hexa, Fluo and Octa compounds' tests were negative for AMES toxicity, indicating that these compounds do not cause genetic mutations. The acute oral toxicity tests yielded values of 1.44 mol/kg for Hexa, 1.939 mol/kg for Fluo and 1.417 mol/kg for Octa. Molecular docking results and bond visualization indicate that the affinity of 9-octadecenoic acid interacts better with RELA and p53 compared to the positive control, i.e. 5-fluorouracil. Hexa compound exhibits a superior binding pocket compared to Fluo and Octa, particularly against the p53 target protein. Hexadecanoic acid compound in Musa paradisiaca var. sapientum (L.) Kuntze represents a breakthrough in developing a new anticancer potential and effectiveness against RELA and p53.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e287760"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of gamma radiations on morphological and biochemical traits of Pisum sativum L. under heavy metal (NiCl2) stress.","authors":"F Ullah, M Irfan, S Khatoon, S Khalil, A Sher, N Alsulami, Y Anwar, A Rauf, A A Mujawah, L S Wong, M Harshini, V Subramaniyan","doi":"10.1590/1519-6984.287016","DOIUrl":"https://doi.org/10.1590/1519-6984.287016","url":null,"abstract":"<p><p>The exposure of plant seeds to gamma radiation is a promising prospect to crop improvement through the manipulation of their genetic makeup. Previous studies have shed light on the potential of radiation to enhance the genetic variability. In this study, we investigated the effect of gamma radiation on Pisum sativum seeds under heavy metal (nickel chloride) stress to determine the changes in morpho-biochemical attributes. Morphological parameters such as germination and photosynthetic pigments while biochemical attributes such as protein content, sugar, phenolics, and flavonoids were determined. The results showed that gamma radiation, along with (NiCl2) has a pronounced effect on plant morphology and production. In the biochemical analysis of the range from 50 Gy to 100 Gy, photosynthetic pigments and proteins were significantly associated. Although the 50 Gy dose induced a partial reduction in sugar content while the 100 Gy dose demonstrated a slight improvement relative to the 50 Gy dose. However, the phenol content increased in response to 50 Gy, whereas the flavonoid content decreased compared to the control. In combination with heavy metal (50mM) at Gy doses, the protein, sugar, phenol, and flavonoid contents showed a gradual decrease with the increase in Gy doses. In conclusion, the current study based on observations suggests that the range of gamma radiation from 50 Gy to 100 Gy is suitable for causing the mutant form of seeds. However, further studies should be conducted to determine the precise mechanism, in order to be benefitted from full potential role of gamma radiation in improving productivity under heavy metal stress.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"84 ","pages":"e287016"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sulfated galactan from Acanthophora muscoides inhibits adipogenesis via regulating adipogenic transcription factors and AMPK in 3T3-L1 cells.","authors":"A V L Silva, R P Lima, F T B Oliveira, A L G Quinderé, N M B Benevides, F A Santos","doi":"10.1590/1519-6984.289036","DOIUrl":"https://doi.org/10.1590/1519-6984.289036","url":null,"abstract":"<p><p>Obesity is a global public health issue, closely linked to cardiovascular disease and type 2 diabetes. Pharmacological interventions for weight loss are one option for treating obesity; however, these drugs often come with side effects or limited efficacy, highlighting the need for new therapies. Marine algae offer a promising source of biologically active compounds for human health, including antidiabetic, anti-inflammatory, and anti-obesity properties. Sulfated galactan isolated from the red marine algae Acanthophora muscoides (SGAM) has demonstrated diverse biological activities including anti-inflammatory activity in vivo and in vitro studies. However, its potential impact on adipogenesis remains unexplored. This study evaluated the effect of SGAM on adipogenesis in 3T3-L1 cells using Oil Red O staining and analyzed the protein expression of key transcription factors associated with adipogenesis. SGAM (25-100 μg/mL) was found to reduce intracellular lipid accumulation in adipocytes without compromising cell viability. Furthermore, our findings suggest that SGAM significantly inhibits adipocyte differentiation by downregulating the expression of key adipogenesis-related transcription factors, including C/EBPβ, C/EBPδ, C/EBPα, and PPARγ. Additionally, SGAM reduced the protein expression of SREBP-1 and promoted the activation of AMPK. In conclusion, SGAM inhibits adipogenesis by negatively modulating the expression of the main adipogenic transcription factors and activating AMPK.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e289036"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Umbelliferone presents orofacial antinociceptive and anti-inflammatory activity via reduction of TNF-α in mice.","authors":"P N S Silva, H N S N Pereira, L V N Santos, L C M M Santos, R J F Cavalcanti, H C Aragão-Neto, R M Braga, F A Gadelha, M R Lopes, D P Sousa, D V Fonsêca","doi":"10.1590/1519-6984.286667","DOIUrl":"https://doi.org/10.1590/1519-6984.286667","url":null,"abstract":"<p><p>Pain is a normal response of the central nervous system to trauma, infections, neoplasms, neuropathies, and inflammation. It can arise from physical, emotional, or cognitive conditions, and is classified as orofacial pain when it affects the mouth and face. Umbelliferone, a coumarin from the umbelliferous plant family, is an important component of essential oils, and possesses antioxidant, curative, anti-inflammatory, and anti-tumor activity. The aim of this study was to investigate the orofacial antinociceptive and anti-inflammatory effects of umbelliferone in Swiss male mice Mus musculus, at 3 months of age. Test groups received different doses of umbelliferone (25, 50, or 75 mg/kg, i.p.). The negative control received 0.9% sodium chloride and Tween 80, with the positive control receiving morphine (5 mg/kg, i.p.) or dexamethasone (2 mg/kg, s.c.). We observed a significant reduction in acetic acid-induced abdominal writhing (p<0.001), and a decrease in paw licking in the orofacial nociception test with formalin (p < 0.01). The 50 and 75 mg/kg doses of umbelliferone presented significant reductions in the glutamate (p<0.01) and capsaicin (p<0.01) tests, suggesting activity on glutamatergic receptors and TRPV1. In the carrageenan-induced paw edema test (1%), there was a decrease in limb volume over 240 minutes (p<0.01), suggesting inhibition of the inflammatory process. There was also a reduction in leukocyte count (p<0.001) and TNF-α levels (p<0.001) when compared to the control group, being similar to the animals treated with dexamethasone (p<0.001). It was concluded that umbelliferone exhibits orofacial antinociceptive activity and anti-inflammatory activity via TNF-α. However, further preclinical studies are needed for a better characterization.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e286667"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Important factors for brand valuation.","authors":"E Amini, S Y Zeraatkish, A Mohammadinejad","doi":"10.1590/1519-6984.289098","DOIUrl":"https://doi.org/10.1590/1519-6984.289098","url":null,"abstract":"<p><p>The present article examines important factors in brand valuation, with a focus on agricultural products in Iran. This article emphasizes the importance of differentiation and branding as tools for gaining a competitive advantage and discusses the role of brand names in guaranteeing quality and encouraging customers to buy products. Brand value is known as one of the key factors in business success, and various models have been introduced to measure this value from the consumer's point of view. The descriptive-survey and comparative research methods were done based on the approaches of operating profit, market, capital expenditures, branding expenditures, and KPMG frameworks, using customer-oriented and organization-oriented approaches as well as behavioral science. The goal of this approach was to understand the financial value and strength of the brand over time and in comparison to competitors in order to guide branding strategies. The necessity of research, the mutual influence of the brand, and the main drivers of the company's value have been investigated, and the advantages of having a strong brand, such as less price sensitivity, increased customer loyalty, and pricing power, have been discussed. Also, the positive relationship between brand value, profitability, and stock performance of companies has been shown through various studies. Emphasizing that brands have become an integral part of everyday life and the economy, the article describes the key methods of valuation. At the end, we came to the comparison of two companies with the said methods.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"84 ","pages":"e289098"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily cycle and environmental factors influence fish assemblage structure in an Amazonian conservation unit.","authors":"R S Silva, L P Oliveira, M Y M Damasceno, M F Noruega, A A Jardim Junior, G T Ferreira, F Corrêa, L J S Vieira, L F A Montag","doi":"10.1590/1519-6984.279923","DOIUrl":"https://doi.org/10.1590/1519-6984.279923","url":null,"abstract":"<p><p>We investigated the influence of daily cycle cycleand local environmental factors on fish assemblages in a terra firme stream in southwestern Amazonia during the rainy season. We collected fish by using sieves and hand-nets over three days and local environmental variables were measured throughout the collection period as well. We employed Generalized Linear Models to examine the impact of daily cycle and local environmental variables on fish species richness and abundance. We used PERMANOVA to assess changes in fish assemblage composition and Redundancy Analysis to understand variations in fish species composition in response to daily cycle and local environmental factors. We collected 18 species and 271 individuals, 111 at night and 160 during the day. Dissolved oxygen (DO) had a positive influence on species richness and abundance and species composition differed between daily cycles. Redundancy Analysis revealed associations between fish species composition, environmental variables (temperature, pH and DO), and daily cycle. These findings underscore the significance of the local environment and daily cycle in predicting variations in fish assemblage structure in Amazonian streams. Understanding how stream fish assemblages are organized temporally is important for devising effective conservation strategies in a region facing increasing human pressures on aquatic ecosystems.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"84 ","pages":"e279923"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavior and mortality of Apis mellifera workers feeding on soft drinks in an urban environment.","authors":"A I A Pereira, L A Ulhoa, C R S Curvêlo, W S Tavares, F L Fernandes, C A D Silva, J C Zanuncio","doi":"10.1590/1519-6984.289658","DOIUrl":"https://doi.org/10.1590/1519-6984.289658","url":null,"abstract":"<p><p>Honeybees (Apis mellifera L.) (Hymenoptera: Apidae) coexists with humans in urban habitats foraging, mainly, sources containing carbohydrates. The behavior and risks for bees using soft drinks in their diet are poorly studied. The time spent by bee workers visiting soft drink leftovers in plastic cups and its death were evaluated. Bee workers spent more time visiting soft drinks in plastic cups (200 mL) than flowers of Schinus sp. (Anacardiaceae), Anadenanthera sp. (Fabaceae), Vernonia sp. (Asteraceae), Citrus sinensis L. (Rutaceae) and Cissus rhombifolia Vahl (Vitaceae), the five most visited honey plants in the field. Drowning mortality and the bee preference varied with the amount of soft drinks leftovers in cups. We present the first study of behavior and drowning mortality of A. mellifera feeding on leftover soft drink in plastic cups in urban areas, in the Brazilian Cerrado biome. This study may help to understanding the adaptive mechanisms of honeybees to explore habitats dominated by humans and unusual diets.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e289658"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective effects of phenolic phytochemicals on male fertility: a narrative review.","authors":"J V Lopes-Ferreira, J E M Matos, F C R Dias, G E M L Siervo, M L M Gomes","doi":"10.1590/1519-6984.288879","DOIUrl":"https://doi.org/10.1590/1519-6984.288879","url":null,"abstract":"<p><p>Infertility is a global health issue and is closely related to oxidative stress, which occurs when high concentrations of free radicals surpass the protective effects of antioxidant molecules and enzymes. Such imbalance causes damage to DNA, as well as cellular proteins and lipids, ultimately leading to the destruction of the blood-testis barrier. This, in turn, hinders spermatogenesis. Various plants and compounds have been employed in an attempt to reverse these damages, such as phenolic compounds. Therefore, this review aims to identify the main phytochemical phenolic compounds and their respective effects when used in the treatment of male infertility. Related information concerning phenolic phytochemical compounds was gathered from studies selected from PubMed, Scopus, and Web of Science databases. The search was conducted using the combination of six terms: \"phenolic compounds\", \"male infertility\", \"testis\", \"spermatozoa\", \"testosterone\" and \"male fertility\". These compounds can raise testosterone levels, reduce lipid peroxidation, and improve tubular histoarchitecture in cases of subfertility associated with diabetes mellitus. They can also mitigate the damage caused by obesity by increasing serum testosterone, antioxidant activity, and sperm motility. When it comes to fertility problems caused by inorganic and organic pollutants, these compounds effectively restore the structure of the seminiferous tubules, increase testosterone levels, and improve sperm quality. Furthermore, phenolic phytochemical compounds have shown beneficial effects in countering the adverse impacts of certain drugs on testicular physiology by reducing apoptosis in testicular tissue, increasing the number of Leydig cells, and promoting spermatocyte production. However, while these compounds may have protective effects on sperm cryopreservation for in vitro fertilization, caution is needed as certain dosages can cause irreversible damage to sperm quality. Overall, plant extracts containing phenolic phytochemical compounds hold promise as a therapeutic avenue for treating infertility and subfertility caused by metabolic disorders and environmental pollutants.</p>","PeriodicalId":55326,"journal":{"name":"Brazilian Journal of Biology","volume":"85 ","pages":"e288879"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}