CytoskeletonPub Date : 2024-10-22DOI: 10.1002/cm.21937
{"title":"Front Cover Image","authors":"","doi":"10.1002/cm.21937","DOIUrl":"https://doi.org/10.1002/cm.21937","url":null,"abstract":"<p>ON THE FRONT COVER: Normal human breast epithelial cells expressing GFP-LIMD1 (green) and tained for F-actin (red) and DNA (blue).</p><p>Credit: Samriddha Ray, Chamika DeSilva, Natasha Cruz-Calderon and Daniel McCollum. University of Massachusetts Chan Medical School Department of Biochemistry and Molecular Biotechnology.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 9-10","pages":"C1"},"PeriodicalIF":2.4,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-10-22DOI: 10.1002/cm.21939
{"title":"Inner Back Cover Image","authors":"","doi":"10.1002/cm.21939","DOIUrl":"https://doi.org/10.1002/cm.21939","url":null,"abstract":"<p>ON THE INNER BACK COVER: Image of the skeletal muscles showing the striated localization pattern of metastasis associated 1 (MTA1).</p><p>Credit: Chundong Gu (The First Affiliated Hospital of Dalian Medical University, Dalian, China) and Ming-Fei Lang (Medical College, Dalian University, Dalian, China)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 9-10","pages":"C3"},"PeriodicalIF":2.4,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21939","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-10-20DOI: 10.1002/cm.21931
{"title":"Picture of the month by Chundong Gu and Ming-Fei Lang","authors":"","doi":"10.1002/cm.21931","DOIUrl":"10.1002/cm.21931","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 9-10","pages":"506"},"PeriodicalIF":2.4,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-10-20DOI: 10.1002/cm.21930
{"title":"Picture of the month by Samriddha Ray, Chamika DeSilva, Natasha Cruz-Calderon, and Daniel McCollum","authors":"","doi":"10.1002/cm.21930","DOIUrl":"10.1002/cm.21930","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 9-10","pages":"505"},"PeriodicalIF":2.4,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-10-10DOI: 10.1002/cm.21948
James R. Sellers
{"title":"Remembrance of Robert S. Adelstein: Mr. Nonmuscle Myosin 2","authors":"James R. Sellers","doi":"10.1002/cm.21948","DOIUrl":"10.1002/cm.21948","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 12","pages":"718-722"},"PeriodicalIF":2.4,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-10-07DOI: 10.1002/cm.21919
Paul J. Griffin
{"title":"Author Profile: Paul Griffin","authors":"Paul J. Griffin","doi":"10.1002/cm.21919","DOIUrl":"10.1002/cm.21919","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 11","pages":"695-696"},"PeriodicalIF":2.4,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-10-01DOI: 10.1002/cm.21942
John A. Hammer
{"title":"Remembrance of Edward D. Korn: A Pioneer in Our Field","authors":"John A. Hammer","doi":"10.1002/cm.21942","DOIUrl":"10.1002/cm.21942","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 12","pages":"713-717"},"PeriodicalIF":2.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-09-27DOI: 10.1002/cm.21935
Jorge Alonso-Eiras, Ines M. Anton
{"title":"Multifaceted role of the actin-binding protein WIP: Promotor and inhibitor of tumor progression and dissemination","authors":"Jorge Alonso-Eiras, Ines M. Anton","doi":"10.1002/cm.21935","DOIUrl":"10.1002/cm.21935","url":null,"abstract":"<p>Cancer cells depend on actin cytoskeleton reorganization to achieve hallmark malignant functions including abnormal activation, proliferation, migration and invasiveness. (Neural)-Wiskott–Aldrich Syndrome protein ((N-)WASP) binds actin and forms a complex with the WASP-interacting protein (WIP), which plays a critical role in regulating the actin cytoskeleton, through (N)-WASP-dependent and independent functions. Mutations in the WIP gene (WIPF1) lead to severe early onset immunodeficiency in humans and severe autoimmunity and shortened lifespan in mice. This review covers the available evidence about the physiological role of WIP in different tissues and its contribution to human disease, focusing on cancer. In solid tumors overexpression of WIP has mostly been associated with tumor initiation, progression and dissemination through matrix degradation by invadopodia, while a suppressive function has been shown for WIP in certain hematological cancers. Interestingly, a minority of studies suggest a protective role for WIP in specific tumor contexts. These data support the need for further research to fully understand the mechanisms underlying WIP's diverse functions in health and disease and raise important questions for future work.</p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"186-196"},"PeriodicalIF":2.4,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21935","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2024-09-25DOI: 10.1002/cm.21932
{"title":"Picture of the month by Aparna Bhattacharyya and Kenneth Barbee","authors":"","doi":"10.1002/cm.21932","DOIUrl":"10.1002/cm.21932","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 9-10","pages":"507"},"PeriodicalIF":2.4,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}