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Author Profile: Halli Lindamood 作者简介：哈利·林达伍德。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2025-01-08 DOI: 10.1002/cm.21984
Halli L. Lindamood
{"title":"Author Profile: Halli Lindamood","authors":"Halli L. Lindamood","doi":"10.1002/cm.21984","DOIUrl":"10.1002/cm.21984","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"219"},"PeriodicalIF":2.4,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Profile: Abigail Allen-Gondringer 作者简介：Abigail Allen-Gondringer。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-28 DOI: 10.1002/cm.21976
Abigail Allen-Gondringer
{"title":"Author Profile: Abigail Allen-Gondringer","authors":"Abigail Allen-Gondringer","doi":"10.1002/cm.21976","DOIUrl":"10.1002/cm.21976","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"216-217"},"PeriodicalIF":2.4,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Profile: Bat-Ider Tumenbayar 作者简介：Bat-Ider Tumenbayar。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-27 DOI: 10.1002/cm.21980
Bat-Ider Tumenbayar
{"title":"Author Profile: Bat-Ider Tumenbayar","authors":"Bat-Ider Tumenbayar","doi":"10.1002/cm.21980","DOIUrl":"10.1002/cm.21980","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"218"},"PeriodicalIF":2.4,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Profile: Katia Brock 作者简介：Katia Brock。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-24 DOI: 10.1002/cm.21978
Katia Brock
{"title":"Author Profile: Katia Brock","authors":"Katia Brock","doi":"10.1002/cm.21978","DOIUrl":"10.1002/cm.21978","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 4","pages":"271"},"PeriodicalIF":2.4,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Profile: Jorge Alonso-Eiras 作者简介：Jorge Alonso-Eiras。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-23 DOI: 10.1002/cm.21985
Jorge Alonso-Eiras
{"title":"Author Profile: Jorge Alonso-Eiras","authors":"Jorge Alonso-Eiras","doi":"10.1002/cm.21985","DOIUrl":"10.1002/cm.21985","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"220"},"PeriodicalIF":2.4,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Profile: Dr. Izra Abbaali 作者简介：Izra Abbaali博士。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-21 DOI: 10.1002/cm.21977
Izra Abbaali
{"title":"Author Profile: Dr. Izra Abbaali","authors":"Izra Abbaali","doi":"10.1002/cm.21977","DOIUrl":"10.1002/cm.21977","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 4","pages":"272-273"},"PeriodicalIF":2.4,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Profile: Kyle Paul Smith 作者简介：凯尔-保罗-史密斯
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-18 DOI: 10.1002/cm.21973
Kyle P. Smith
{"title":"Author Profile: Kyle Paul Smith","authors":"Kyle P. Smith","doi":"10.1002/cm.21973","DOIUrl":"10.1002/cm.21973","url":null,"abstract":"","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 6","pages":"404-405"},"PeriodicalIF":2.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FAK and p130Cas Modulate Stiffness-Mediated Early Transcription and Cellular Metabolism FAK和p130Cas调节刚度介导的早期转录和细胞代谢。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-09 DOI: 10.1002/cm.21971
Bat-Ider Tumenbayar, Khanh Pham, John C. Biber, Vincent M. Tutino, Joseph A. Brazzo III, Peng Yao, Yongho Bae
{"title":"FAK and p130Cas Modulate Stiffness-Mediated Early Transcription and Cellular Metabolism","authors":"Bat-Ider Tumenbayar,&nbsp;Khanh Pham,&nbsp;John C. Biber,&nbsp;Vincent M. Tutino,&nbsp;Joseph A. Brazzo III,&nbsp;Peng Yao,&nbsp;Yongho Bae","doi":"10.1002/cm.21971","DOIUrl":"10.1002/cm.21971","url":null,"abstract":"<div>\u0000 \u0000 <p>Cellular metabolism is influenced by the stiffness of the extracellular matrix. Focal adhesion kinase (FAK) and its binding partner, p130Cas, transmit biomechanical signals, such as substrate stiffness, to the cell to regulate a variety of cellular responses, but their roles in early transcriptional and metabolic responses remain largely unexplored. We cultured mouse embryonic fibroblasts with or without siRNA-mediated FAK or p130Cas knockdown and assessed the early transcriptional responses of these cells to placement on soft and stiff substrates by RNA sequencing and bioinformatics analyses. Exposure to the stiff substrate altered the expression of genes important for metabolic and biosynthetic processes, and these responses were influenced by knockdown of FAK and p130Cas. Our findings reveal that FAK-p130Cas signaling mechanotransduces substrate stiffness to early transcriptional changes that alter cellular metabolism and biosynthesis.</p>\u0000 </div>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"197-215"},"PeriodicalIF":2.4,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis 作为生物力学控制肿瘤转移的一种范式。
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-05 DOI: 10.1002/cm.21963
Grace Cai, Nicole C. Rodgers, Allen P. Liu
{"title":"Unjamming Transition as a Paradigm for Biomechanical Control of Cancer Metastasis","authors":"Grace Cai,&nbsp;Nicole C. Rodgers,&nbsp;Allen P. Liu","doi":"10.1002/cm.21963","DOIUrl":"10.1002/cm.21963","url":null,"abstract":"<p>Tumor metastasis is a complex phenomenon that poses significant challenges to current cancer therapeutics. While the biochemical signaling involved in promoting motile phenotypes is well understood, the role of biomechanical interactions has recently begun to be incorporated into models of tumor cell migration. Specifically, we propose the unjamming transition, adapted from physical paradigms describing the behavior of granular materials, to better discern the transition toward an invasive phenotype. In this review, we introduce the jamming transition broadly and narrow our discussion to the different modes of 3D tumor cell migration that arise. Then we discuss the mechanical interactions between tumor cells and their neighbors, along with the interactions between tumor cells and the surrounding extracellular matrix. We center our discussion on the interactions that induce a motile state or unjamming transition in these contexts. By considering the interplay between biochemical and biomechanical signaling in tumor cell migration, we can advance our understanding of biomechanical control in cancer metastasis.</p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 6","pages":"388-403"},"PeriodicalIF":2.4,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Front Cover Image 封面图片
IF 2.4 4区 生物学
Cytoskeleton Pub Date : 2024-12-04 DOI: 10.1002/cm.21965
{"title":"Front Cover Image","authors":"","doi":"10.1002/cm.21965","DOIUrl":"https://doi.org/10.1002/cm.21965","url":null,"abstract":"<p>ON THE FRONT COVER: Myosin A staining in the earliest stages of muscle cytoskeletal organization in a comma-stage C. elegans embryos shows an anterior-posterior gradient in the organization of myosin A into a striated pattern.</p><p>Credit: Kar Men Lee and Hao Peng (Western Michigan University Department of Biological Sciences).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"81 12","pages":"C1"},"PeriodicalIF":2.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.21965","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142762264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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