CytoskeletonPub Date : 2025-05-09DOI: 10.1002/cm.22038
{"title":"Back Cover Image","authors":"","doi":"10.1002/cm.22038","DOIUrl":"https://doi.org/10.1002/cm.22038","url":null,"abstract":"<p>ON THE BACK COVER: PC3 cells stained for Lamin A/C (red), mVenus-HN1 (Green) and DNA (Blue).</p><p>Credit: Gülseren Özduman and Kemal Sami Korkmaz (Cancer Biology Laboratory, Department of Bioengineering, Faculty of Engineering, Ege University, Bornova, Turkey)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 5","pages":"C4"},"PeriodicalIF":2.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-05-09DOI: 10.1002/cm.22039
{"title":"Front Cover Image","authors":"","doi":"10.1002/cm.22039","DOIUrl":"https://doi.org/10.1002/cm.22039","url":null,"abstract":"<p>ON THE FRONT COVER: Composite image of in HN1 depleted PC3 cells stained for β-tubulin (green) and DNA (Blue).</p><p>Credit: Gülseren Özduman and Kemal Sami Korkmaz (Cancer Biology Laboratory, Department of Bioengineering, Faculty of Engineering, Ege University, Bornova, Turkey)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 5","pages":"C1"},"PeriodicalIF":2.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143925987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-04-23DOI: 10.1002/cm.22028
Rylee E. King, Marin Herrick, Justin Parreno
{"title":"Actin-Bundling Protein, Fascin-1, as a Target of Osteoarthritis Progression","authors":"Rylee E. King, Marin Herrick, Justin Parreno","doi":"10.1002/cm.22028","DOIUrl":"10.1002/cm.22028","url":null,"abstract":"<div>\u0000 \u0000 <p>The cellular mechanisms underlying osteoarthritis pathogenesis are not fully understood. However, recent <i>in vivo</i> and <i>in vitro</i> studies show that actin cytoskeletal reorganization plays a critical role in the progression of osteoarthritis. It has been shown that targeting the inhibition of actin-bundling protein, fascin, is a favorable way to reorganize actin and prevent chondrocyte dedifferentiation that occurs in osteoarthritis. In a surgical model of osteoarthritis, targeting fascin reduces cartilage degradation and disease severity. These findings highlight the therapeutic potential of targeting fascin in osteoarthritis. Future research to develop a further mechanistic understanding on the critical role actin and actin network molecules play in osteoarthritis may lead to the development of actin-based therapies against disease progression.</p>\u0000 </div>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 9","pages":"601-606"},"PeriodicalIF":1.6,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-04-02DOI: 10.1002/cm.22023
{"title":"Inner Front Cover Image","authors":"","doi":"10.1002/cm.22023","DOIUrl":"https://doi.org/10.1002/cm.22023","url":null,"abstract":"<p>ON THE INNER FRONT COVER: Spermatocytes of Drosophila melanogaster during anaphase of the first meiosis stained for tubulin (green), the kinesin-like Pavarotti (red) and DNA (blue).</p><p>Credit: Maria Giovanna Riparbelli and Giuliano Callaini (University of Siena, Siena, Italy)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 4","pages":"C2"},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-04-02DOI: 10.1002/cm.22022
{"title":"Front Cover Image","authors":"","doi":"10.1002/cm.22022","DOIUrl":"https://doi.org/10.1002/cm.22022","url":null,"abstract":"<p>ON THE FRONT COVER: Spermatocytes of Drosophila melanogaster during metaphase and anaphase of the first meiosis stained for tubulin (green), the kinesin-like Pavarotti (red) and DNA (blue).</p><p>Credit: Maria Giovanna Riparbelli and Giuliano Callaini (University of Siena, Siena, Italy)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 4","pages":"C1"},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-04-02DOI: 10.1002/cm.22025
{"title":"Back Cover Image","authors":"","doi":"10.1002/cm.22025","DOIUrl":"https://doi.org/10.1002/cm.22025","url":null,"abstract":"<p>ON THE BACK COVER: Disruption of the actin cytoskeleton by latrunculin B promotes the translocation of Core-binding factor subunit beta (red) to the cytoplasm of human skeletal muscle. F-actin (green) and DNA (blue) are also shown.</p><p>Credit: Yaxin Li and Fumihiko Nakamura (Tianjin University, School of Pharmaceutical Science and Technology, China)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 4","pages":"C4"},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-04-02DOI: 10.1002/cm.22024
{"title":"Inner Back Cover Image","authors":"","doi":"10.1002/cm.22024","DOIUrl":"https://doi.org/10.1002/cm.22024","url":null,"abstract":"<p>ON THE INNER BACK COVER: GMPCPP stabilized microtubules assembled from 1 μM mung tubulin incubated at 37°C for 114 hours.</p><p>Credit: Jashaswi Basu and Chaitanya Athale (Indian Institute of Science Education and Research Pune, India)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 4","pages":"C3"},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-03-13DOI: 10.1002/cm.22016
{"title":"Inner Front Cover Image","authors":"","doi":"10.1002/cm.22016","DOIUrl":"https://doi.org/10.1002/cm.22016","url":null,"abstract":"<p>ON THE INNER FRONT COVER: Zebrafish heart. Immunofluorescence staining of actinin-2 (red) and phalloidin staining (green).</p><p>Credit: Klimenko E.S., Makhnin I.A. (Almazov National Medical Research Centre, Institute of molecular biology and genetics, Saint-Petersburg, Russia)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"C2"},"PeriodicalIF":2.4,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
CytoskeletonPub Date : 2025-03-13DOI: 10.1002/cm.22018
{"title":"Back Cover Image","authors":"","doi":"10.1002/cm.22018","DOIUrl":"https://doi.org/10.1002/cm.22018","url":null,"abstract":"<p>ON THE BACK COVER: C2C12-myotubes. Immunofluorescence staining of TRPC1 channel (red) and phalloidin staining (green).</p><p>Credit: Klimenko E.S., Sukhareva K.S. (Almazov National Medical Research Centre, Institute of molecular biology and genetics, Saint-Petersburg, Russia)\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":55186,"journal":{"name":"Cytoskeleton","volume":"82 3","pages":"C4"},"PeriodicalIF":2.4,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cm.22018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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