Depression and Anxiety最新文献

{"title":"How Do Patients’ Fear Prediction and Fear Experience Impact Exposure-Based Therapy for Panic Disorder With Agoraphobia? A Comprehensive Analysis of Fear Prediction","authors":"Marina Hilleke,&nbsp;Thomas Lang,&nbsp;Sylvia Helbig-Lang,&nbsp;Georg W. Alpers,&nbsp;Volker Arolt,&nbsp;Jürgen Deckert,&nbsp;Thomas Fydrich,&nbsp;Alfons O. Hamm,&nbsp;Tilo Kircher,&nbsp;Jan Richter,&nbsp;Andreas Ströhle,&nbsp;Hans-Ulrich Wittchen,&nbsp;Alexander L. Gerlach","doi":"10.1155/da/6963860","DOIUrl":"https://doi.org/10.1155/da/6963860","url":null,"abstract":"<div>\u0000 <p>Expectancy violation has been proposed as a potential core mechanism of action in psychotherapy, particularly in exposure therapy for anxiety disorders. However, various relevant expectations have been discussed, and empirical studies examining their significance are still scarce. This study aimed to investigate one specific form of expectancy violation, based on Rachman’s (1994) match-mismatch model, specifically by comparing expected and experienced fear and examining their relationship to safety behaviour during exposure in vivo in 268 patients meeting DSM-IV criteria for panic disorder with agoraphobia. Participants underwent exposure to a highly controlled manual-based cognitive behaviour therapy in a randomised multicenter psychotherapy study. Participants tended to overpredict fear during exposure. Both expected and experienced fear significantly decreased over the course of repeated exposure exercises, while prediction (in)accuracy (difference between expected and experienced fear) remained stable. The decrease in expected fear over time was a strong predictor of treatment outcomes for the Bodily Sensations Questionnaire (BSQ) and Panic and Agoraphobia Scale (PAS) at post. Even more, the reduction in expected fear was a significant predictor of treatment success across all outcome measures in the follow-up assessment. These findings suggest that violating excessive fear expectancies is not a necessary condition for symptom reduction during exposure therapy.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/6963860","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive and Insomnia Symptoms Among Older Adults With Different Chronic Pain Trajectories: A Network Analysis Based on Observation Over an Eight-Year Period","authors":"He-Li Sun,&nbsp;Pan Chen,&nbsp;Wei Bai,&nbsp;Yuan Feng,&nbsp;Sha Sha,&nbsp;Zhaohui Su,&nbsp;Teris Cheung,&nbsp;Chee H. Ng,&nbsp;Qinge Zhang,&nbsp;Yu-Tao Xiang","doi":"10.1155/da/8065167","DOIUrl":"https://doi.org/10.1155/da/8065167","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Depressive and insomnia symptoms are common among older adults with chronic pain. We aimed to examine different chronic pain trajectories of older adults over an 8-year observation period and explore the network structures of depression and insomnia in each chronic pain group.</p>\u0000 <p><b>Methods:</b> The trajectories of pain in the USA-based Health and Retirement Study (HRS) data from 2010 to 2018 were examined using latent class growth analyses (LCGA) method. Depressive and insomnia symptoms were measured with the eight-item version of the Center for Epidemiological Studies Depression (CESD-8) Scale and the four-item Jenkins Sleep Scale (JSS-4), respectively. Network models were constructed using the Ising model. Central symptoms and bridge symptoms were identified via expectedInfluence (EI) and bridge EI, respectively.</p>\u0000 <p><b>Results:</b> A total of 11,132 older adults were included in the trajectory analysis, with three chronic pain trajectories identified, including “severe pain trajectory,” “moderate pain trajectory,” and “non or mild pain trajectory”. From these trajectories, “Lack of happiness” (CESD4), “Feeling depressed” (CESD1), and “Feeling sad” (CESD7) emerged as the most central symptoms, while “Feeling tired in the morning” (JSS4) was identified as the key bridge symptom. However, the findings may not be generalizable to other parts of the world outside the USA.</p>\u0000 <p><b>Conclusion:</b> Older adults with different chronic pain trajectories exhibited similar depression and insomnia network structure. Implementing timely interventions that target central and bridge symptoms might mitigate the co-occurrence of depression and insomnia in this population.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/8065167","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Activation Likelihood Estimation Meta-Analysis of the Effects of Cognitive Behavioral Therapy on Brain Activation in the Treatment of Depression and Anxiety Disorders","authors":"Junjie Ren,&nbsp;Lijun Ma,&nbsp;Wanxin Wu,&nbsp;Juan Qiu,&nbsp;Zhuo Zhang,&nbsp;Yuxi Hong,&nbsp;Zushen Wang,&nbsp;Xinyu Hou,&nbsp;Jia Jin,&nbsp;Weixuan Hu,&nbsp;Yanran Wu,&nbsp;Xiaowei Chen,&nbsp;Jinyi Luo,&nbsp;Chuan Fan,&nbsp;Kai Wang,&nbsp;Xiaoming Li","doi":"10.1155/da/3557367","DOIUrl":"https://doi.org/10.1155/da/3557367","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Cognitive behavioral therapy (CBT) stands as a highly efficacious psychological treatment for both anxiety and depressive disorders. Nonetheless, scholarly debates persist regarding the specificities of brain area activation during CBT treatment for these disorders.</p>\u0000 <p><b>Methodology:</b> Utilizing activation likelihood estimation (ALE) analysis, this study aims to discern the neurobiological similarities and disparities between CBT’s effects on anxiety and depressive disorders by examining functional brain areas.</p>\u0000 <p><b>Results:</b> A total of 22 articles, encompassing 443 patients, were included in the meta-analysis. Our results show that in the resting state, patients with depression treated with CBT resulted in increased activation of the right and left ventral anterior cingulate cortex (vACC), left parahippocampal gyrus (PG), right subgyral, left inferior temporal gyrus (ITG), and right inferior occipital gyrus (IOG), whereas patients with anxiety disorders had increased activation of the right and left superior frontal gyrus (SFG) and decreased activation of the caudate after treatment. In the task state, increased activation of the right PG, right orbital frontal lobe, and right dorsal anterior cingulate cortex (dACC) was mainly observed after treatment in patients with anxiety disorders, and the left lentiform nucleus (LN), left dorsal entorhinal cortex, and right caudate activation were decreased. For depressive disorders, no consistent activation patterns emerged in the task state, likely due to limited studies or heterogeneity in task paradigms across included studies.</p>\u0000 <p><b>Conclusion:</b> CBT’s efficacy relies on both shared (e.g., vACC-mediated emotion regulation and cognitive control) and distinct neural mechanisms (fear-circuit modulation in anxiety vs. memory-network enhancement in depression), informing biomarker-driven treatment personalization.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/3557367","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Pain and Depressive Symptoms: Patterns and Associations in Middle-Aged and Older Chinese Adults","authors":"Xiaohui Wu,&nbsp;Ruyan Huang,&nbsp;Yue Fei,&nbsp;Rongrong Zhong,&nbsp;Shuo Wang,&nbsp;Xiaojia Huang,&nbsp;Zuowei Wang,&nbsp;Yuncheng Zhu,&nbsp;Yiru Fang","doi":"10.1155/da/4027080","DOIUrl":"https://doi.org/10.1155/da/4027080","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Depressive symptoms (DS) and body pain are prevalent conditions that significantly impact the quality of life of older adults, often co-occurring with chronic diseases. This study aimed to explore the patterns of body pain characteristics and their association with DS among middle-aged and older Chinese adults.</p>\u0000 <p><b>Methods:</b> This cross-sectional study analysed data from 16,039 participants aged ≥45 years in the 2020 wave of the China Health and Retirement Longitudinal Study (CHARLS). DS were assessed using the 10-item Centre for Epidemiologic Studies Depression Scale (CESD-10). Body pain characteristics included pain severity and location. Multiple linear regression and mediation analyses were conducted to examine the relationships between chronic diseases, body pain, and DS.</p>\u0000 <p><b>Results:</b> Among participants, 5442 (33.9%) reported DS (CESD-10 score ≥12). The DS group showed significantly higher body pain severity (2.66 ± 1.42 vs. 1.84 ± 1.11, <i>p</i> &lt; 0.001) and more painful body parts (5.06 ± 3.87 vs. 3.68 ± 3.03, <i>p</i> &lt; 0.001) compared to the non-depressive group. Both pain severity and number of pain sites were independently associated with higher CESD-10 scores. Mediation analysis revealed that body pain severity mediated 29.0% of the total effect between chronic diseases and DS.</p>\u0000 <p><b>Conclusion:</b> Body pain plays a significant mediating role in the relationship between chronic diseases and DS among middle-aged and older Chinese adults. These findings emphasize the importance of implementing comprehensive healthcare approaches that integrate pain management with mental health support in primary care settings.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/4027080","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Speech Features and Machine Learning Models to Predict Emotional and Behavioral Problems in Chinese Adolescents","authors":"Jinyu Li,&nbsp;Yang Wang,&nbsp;Fei Wang,&nbsp;Ran Zhang,&nbsp;Ning Wang,&nbsp;Yue Zhu,&nbsp;Taihong Zhao","doi":"10.1155/da/5734107","DOIUrl":"https://doi.org/10.1155/da/5734107","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Current assessments of adolescent emotional and behavioral problems rely heavily on subjective reports, which are prone to biases.</p>\u0000 <p><b>Aim:</b> This study is the first to explore the potential of speech signals as objective markers for predicting emotional and behavioral problems (hyperactivity, emotional symptoms, conduct problems, and peer problems) in adolescents using machine learning techniques.</p>\u0000 <p><b>Materials and Methods:</b> We analyzed speech data from 8215 adolescents aged 12–18 years, extracting four categories of speech features: mel-frequency cepstral coefficients (MFCC), mel energy spectrum (MELS), prosodic features (PROS), and formant features (FORM). Machine learning models—logistic regression (LR), support vector machine (SVM), and gradient boosting decision trees (GBDT)—were employed to classify hyperactivity, emotional symptoms, conduct problems, and peer problems as defined by the Strengths and Difficulties Questionnaire (SDQ). Model performance was assessed using area under the curve (AUC), F1-score, and Shapley additive explanations (SHAP) values.</p>\u0000 <p><b>Results:</b> The GBDT model achieved the highest accuracy for predicting hyperactivity (AUC = 0.78) and emotional symptoms (AUC = 0.74 for males and 0.66 for females), while performance was weaker for conduct and peer problems. SHAP analysis revealed gender-specific feature importance patterns, with certain speech features being more critical for males than females.</p>\u0000 <p><b>Conclusion:</b> These findings demonstrate the feasibility of using speech features to objectively predict emotional and behavioral problems in adolescents and identify gender-specific markers. This study lays the foundation for developing speech-based assessment tools for early identification and intervention, offering an objective alternative to traditional subjective evaluation methods.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/5734107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144292956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Cross-Lagged Relationships of Complex Post-Traumatic Stress Disorder, Depression, and Anxiety Among Adolescents and Emerging Adults With Childhood Bullying Victimization Experiences","authors":"Mingxiao Liu,&nbsp;Aiyi Liu,&nbsp;Sihan Liu,&nbsp;Boya Xu,&nbsp;Xinchun Wu","doi":"10.1155/da/9166230","DOIUrl":"https://doi.org/10.1155/da/9166230","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Individuals who have experienced bullying victimization often develop symptoms of complex post-traumatic stress disorder (CPTSD), depression, and anxiety, with these symptoms mutually influencing one another. This study aims to explore the reciprocal relationships between CPTSD, depression, and anxiety among adolescents and emerging adults who have experienced childhood bullying victimization, from both variable-level and symptom-level perspectives.</p>\u0000 <p><b>Method:</b> A total of 3945 adolescents and 2726 emerging adults with childhood bullying victimization experiences were measured 6-month interval in the study. All the participants completed the questionnaires assessing for bullying victimization, CPTSD, depression, and anxiety. The data were analyzed using cross-lagged panel analysis and cross-lagged network analysis.</p>\u0000 <p><b>Results:</b> The cross-lagged panel analysis reveals that CPTSD more strongly and consistently predicts depression and anxiety, whereas the reverse influence is weaker across both groups. At the symptom level, for adolescents, “death” (in depression) influences “feel worthless” (in CPTSD) and “feel like a failure” (in CPTSD). Additionally, “death” (in depression) is more likely to predict subsequent symptoms, while “feel like a failure” (in CPTSD) is more frequently activated by other symptoms. In the emerging adults, some strong cross-lagged effects were observed, such as “motor” (in depression) to “traumatic dreams” (in CPTSD) and “worthless” (in depression) to “feel like a failure” (in CPTSD). In addition, “exaggerated startle” (in CPTSD) tends to predict symptoms, while “feel like a failure” (in CPTSD) is more frequently activated.</p>\u0000 <p><b>Conclusions:</b> Findings suggested that interventions alleviating “death” (in depression) among adolescents and “exaggerated startle” (in CPTSD) among emerging adults may improve overall mental health.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/9166230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144281548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a Mindfulness-Based Intervention on Symptoms and Emotion Regulation Strategies in Young Adolescents From the General Population: A Randomized Controlled Trial","authors":"Camille Piguet,&nbsp;Zeynep Celen,&nbsp;Ben Meuleman,&nbsp;Zoé Schilliger,&nbsp;Mariana Magnus Smith,&nbsp;Erik Mendola,&nbsp;Eleonore Pham,&nbsp;Sondes Jouabli,&nbsp;Vladimira Ivanova,&nbsp;Ryan J. Murray,&nbsp;Paul Klauser,&nbsp;Arnaud Merglen","doi":"10.1155/da/2679049","DOIUrl":"https://doi.org/10.1155/da/2679049","url":null,"abstract":"<div>\u0000 <p>Adolescence is marked by major puberty-induced changes including increased reactivity to stress and a peak incidence of mental disorders. The implementation of early interventions during this developmental period is essential to prevent mental disorders. In this clinical trial, we examined the effects of a mindfulness-based intervention (MBI) on internalizing symptoms, affects, and emotion-regulation strategies in a nonclinical sample of young adolescents. Seventy adolescents (41 girls) from the general population, aged between 13 and 15 years, were enrolled in a randomized controlled trial (RCT) that compared an 8-week MBI designed for adolescents and a waiting list. Levels of stress, anxiety and depressive symptoms, positive and negative affects, as well as emotion regulation strategies were measured before and after the intervention (4.8 weeks ± 4 SD) using self-reported questionnaires. We found no effect of our MBI on all self-reported measures, including stress, anxiety, depression, and positive and negative affects, as well as an emotion regulation strategies. Trait mindfulness was negatively correlated with measures of stress, anxiety, and negative affects. The intervention was very well accepted (only one dropout) with a high degree of satisfaction among participants. Individual responses to the intervention were very heterogeneous. Mindfulness practice in non-help-seeking adolescents was very well received, but did not show any benefit on symptoms, affects, or emotion regulation. This is consistent with the literature suggesting a better response in clinical than in nonclinical samples. Longer-term effects remain to be investigated, as does the possibility of identifying individuals who respond best to this early intervention.</p>\u0000 <p><b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT04711694</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/2679049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144244987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Correlation Analysis of Monthly Google Search Volume and Suicide in Taiwan, 2012–2022","authors":"Cheng-Fang Yen,&nbsp;Yu-Hsuan Lin,&nbsp;Ray C. Hsiao,&nbsp;Ying-Yeh Chen,&nbsp;Yi-Lung Chen","doi":"10.1155/da/5515746","DOIUrl":"https://doi.org/10.1155/da/5515746","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> The present study investigated the 1-month, 2-month, and 3-month prospective associations of Google search terms with suicide in Taiwan from 2012 to 2022.</p>\u0000 <p><b>Methods:</b> We analyzed daily suicide data from Taiwan’s Cause of Death Statistics between January 1, 2012, and December 31, 2022. Data on Google search volumes for 37 terms related to suicide-related, socioeconomic status, familial problems, and physical and psychiatric problems were extracted from Google Trends. Cross-correlation coefficients between monthly Google search term volumes and monthly suicide were calculated at lags of 3 months (lag-3), 2 months (lag-2), and 1 month (lag-1).</p>\u0000 <p><b>Results:</b> The monthly Google search volumes of two terms, “pain” and “Taiwan economy”, positively predicted monthly suicide in the total population. The search term “hypnotic” lag-3 negatively correlated with monthly suicide in the population aged ≥65. The search term “allergy” lag-1 positively correlated with monthly suicide in the population aged ≥65.</p>\u0000 <p><b>Conclusions:</b> The monthly Google search terms of “pain” and “Taiwan economy” positively correlated with monthly suicide. The search terms “hypnotic” and “allergy” negatively and positively correlated with monthly suicide in the population aged ≥65, respectively. These terms may enable more accurate forecasting of future suicides.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/5515746","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144213974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collaborative Care Versus Consultation Liaison for Patients With Depression or Anxiety Disorders in General Practice in Denmark: 18-Month Follow-Up From the Collabri Flex Trials","authors":"Nadja Kehler Curth,&nbsp;Siv Therese Bogevik Bjørkedal,&nbsp;Carsten Hjorthøj,&nbsp;Ursula Brinck-Claussen,&nbsp;Kirstine Bro Jørgensen,&nbsp;Susanne Rosendal,&nbsp;Anders Bo Bojesen,&nbsp;Merete Nordentoft,&nbsp;Lene Falgaard Eplov","doi":"10.1155/da/2909617","DOIUrl":"https://doi.org/10.1155/da/2909617","url":null,"abstract":"<div>\u0000 <p><b>Introduction:</b> To our knowledge, no research has reported long-term follow-up results from studies comparing collaborative care to consultation liaison in general practice. We have earlier reported 6-month follow-up. In this article, we report the 18-month follow-up results from the two Danish Collabri Flex studies.</p>\u0000 <p><b>Methods:</b> We compared collaborative care to consultation liaison in two randomized controlled trials for persons with anxiety disorders and depression, respectively. Both interventions sought to improve the quality of depression and anxiety care, but they differed in the extent mental health specialists were involved. As part of the consultation liaison intervention, psychiatrists and care managers could provide advice and suggestions to the general practitioner (GP). In the collaborative care intervention, psychiatrists and care managers could provide advice and suggestions, and care managers could help the GP manage patient care. 18 months after randomization, we collected follow-up data. Outcomes included anxiety symptoms (BAI), depression symptoms (BDI-II), well-being (WHO-5), functional disability (Sheehan Disability Scale), general psychological symptoms (SCL-90-R), and others.</p>\u0000 <p><b>Results:</b> In the depression trial, we found a statistically significant difference in depression symptoms between intervention groups at 18-month follow-up, in favor of collaborative care (4.4, 95%CI 2.8–7.0, <i>p</i> ≤ 0.001). Many other outcomes showed significant differences between groups, such as anxiety symptoms, functional level, well-being, general psychological symptoms, and self-efficacy. In the anxiety trial, we found no statistically significant difference between groups in anxiety symptoms (1.2, 95%CI −0.3–2.7, <i>p</i> ≤ 0.126). In this trial, significant differences between groups were found in outcomes measuring depression symptoms and general psychological symptoms but not in outcomes measuring functional level, well-being or self-efficacy. In both trials, no differences were found between groups on employment/education or sick leave measures. However, the collaborative care group in both trials had fewer contacts with private practicing psychologists during the 18 months follow-up.</p>\u0000 <p><b>Conclusion:</b> At 18-month follow-up, we found a statistically significant difference between allocation groups, when measuring depression symptoms in the depression trial but not when measuring anxiety symptoms in the anxiety trial. Further, the collaborative care intervention may have the potential to reduce referrals to private practicing psychologists, a service that is in high demand in Denmark.</p>\u0000 <p><b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT03113175 and NCT03113201</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/2909617","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality Traits, Stress, Anxiety, Depression Levels, Fear of Childbirth, and Affecting Factors in Turkish University Students","authors":"Nülüfer Erbil,&nbsp;Hilal Gül Boyraz Yanık,&nbsp;Gizem Yıldız","doi":"10.1155/da/5130737","DOIUrl":"https://doi.org/10.1155/da/5130737","url":null,"abstract":"<div>\u0000 <p><b>Objectives:</b> This study was conducted to investigate the personality traits, stress, anxiety, depression levels, fear of childbirth, and affecting factors in Turkish female university students.</p>\u0000 <p><b>Materials and Methods:</b> The study was planned as a descriptive and correlational type. The sample consisted of 500 female students who met the research criteria at the Faculty of Health Sciences and Faculty of Education of a university. The data were collected face-to-face using a personal information form, including socio-demographic and pregnancy-birth-related thoughts, the Childbirth Fear–Prior to Pregnancy (CFPP) scale, the Type D Personality Scale (negative affectivity and social inhibition subscales), and the Depression Anxiety Stress Scale-21 (DASS-21). Ethics committee approval and institutional permissions were obtained from the students to conduct the study. In the analysis of the data, the Kolmogorov–Smirnov test, descriptive methods Mann–Whitney <i>U</i>, and the Kruskal–Wallis test were used.</p>\u0000 <p><b>Results:</b> 52.8% of the students were from the Faculty of Health Sciences, 48.4% were nursing students, and 30.6% were in their first class of students. The mean CFPP score was 40.14 ± 11.35. The mean score was 12.01 ± 6.79 for negative affectivity, 9.58 ± 6.09 for social inhibition, 6.75 ± 4.05 for stress, 5.28 ± 4.09 for anxiety, and 5.58 ± 4.50 for depression. There was a low level of positive correlation between CFPP and social inhibition subscales (<i>r</i> = 0.113), negative affectivity (<i>r</i> = 0.282), stress (<i>r</i> = 0.241), anxiety (<i>r</i> = 0.231), and depression (<i>r</i> = 0.221 (<i>p</i> = 0.01). The predictor of students’ fear of childbirth prior to pregnancy was negative affectivity.</p>\u0000 <p><b>Conclusions:</b> Turkish university students’ fear of childbirth prior to pregnancy was associated with personality traits, depression, anxiety, and stress. It is recommended to identify the depression, anxiety, stress levels, personality traits, and fear of childbirth of female university students in the prepregnancy period, plan information and education, and conduct further research on the fear of childbirth.</p>\u0000 </div>","PeriodicalId":55179,"journal":{"name":"Depression and Anxiety","volume":"2025 1","pages":""},"PeriodicalIF":4.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/da/5130737","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}