Genes and NutritionPub Date : 2017-01-25eCollection Date: 2017-01-01DOI: 10.1186/s12263-016-0549-8
Jim Kaput, Giuditta Perozzi, Marijana Radonjic, Fabio Virgili
{"title":"Propelling the paradigm shift from reductionism to systems nutrition.","authors":"Jim Kaput, Giuditta Perozzi, Marijana Radonjic, Fabio Virgili","doi":"10.1186/s12263-016-0549-8","DOIUrl":"10.1186/s12263-016-0549-8","url":null,"abstract":"<p><p>The complex physiology of living organisms represents a challenge for mechanistic understanding of the action of dietary bioactives in the human body and of their possible role in health and disease. Animal, cell, and microbial models have been extensively used to address questions that could not be pursued experimentally in humans, posing an additional level of complexity in translation of the results to healthy and diseased metabolism. The past few decades have witnessed a surge in development of increasingly sensitive molecular techniques and bioinformatic tools for storing, managing, and analyzing increasingly large datasets. Application of such powerful means to molecular nutrition research led to a major leap in study designs and experimental approaches yielding experimental data connecting dietary components to human health. Scientific journals bear major responsibilities in the advancement of science. As primary actors of dissemination to the scientific community, journals can impose rigid criteria for publishing only sound, reliable, and reproducible data. Journal policies are meant to guide potential authors to adopt the most updated standardization guidelines and shared best practices. Such policies evolve in parallel with the evolution of novel approaches and emerging challenges and therefore require constant updating. We highlight in this manuscript the major scientific issues that led to formulating new, updated journal policies for <i>Genes & Nutrition</i>, a journal which targets the growing field of nutritional systems biology interfacing personalized nutrition and preventive medicine, with the ultimate goal of promoting health and preventing or treating disease. We focus here on relevant issues requiring standardization in nutrition research. We also introduce new sections on human genetic variation and nutritional bioinformatics which follow the evolution of nutritional science into the twenty-first century.</p>","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2017-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0549-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47789109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Drag, A. Goździalska, M. Knapik-Czajka, A. Gawedzka, K. Gawlik, J. Jaśkiewicz
{"title":"Effect of high carbohydrate diet on elongase and desaturase activity and accompanying gene expression in rat’s liver","authors":"J. Drag, A. Goździalska, M. Knapik-Czajka, A. Gawedzka, K. Gawlik, J. Jaśkiewicz","doi":"10.1186/s12263-017-0551-9","DOIUrl":"https://doi.org/10.1186/s12263-017-0551-9","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2017-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-017-0551-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Furuse, Kunio Miyake, T. Kohda, H. Kaneda, T. Hirasawa, Ikuko Yamada, Tomoko Kushida, Misho Kashimura, Kimio Kobayashi, F. Ishino, T. Kubota, S. Wakana
{"title":"Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny","authors":"T. Furuse, Kunio Miyake, T. Kohda, H. Kaneda, T. Hirasawa, Ikuko Yamada, Tomoko Kushida, Misho Kashimura, Kimio Kobayashi, F. Ishino, T. Kubota, S. Wakana","doi":"10.1186/s12263-016-0550-2","DOIUrl":"https://doi.org/10.1186/s12263-016-0550-2","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2017-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0550-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raffaella Comitato, B. Guantario, G. Leoni, K. Nesaretnam, Maria Beatrice Ronci, R. Canali, F. Virgili
{"title":"Tocotrienols induce endoplasmic reticulum stress and apoptosis in cervical cancer cells","authors":"Raffaella Comitato, B. Guantario, G. Leoni, K. Nesaretnam, Maria Beatrice Ronci, R. Canali, F. Virgili","doi":"10.1186/s12263-016-0543-1","DOIUrl":"https://doi.org/10.1186/s12263-016-0543-1","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0543-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum to: 18β-Glycyrrhetinic acid exerts protective effects against cyclophosphamide-induced hepatotoxicity: potential role of PPARγ and Nrf2 upregulation","authors":"A. Mahmoud, Hussein S. Al Dera","doi":"10.1186/s12263-016-0548-9","DOIUrl":"https://doi.org/10.1186/s12263-016-0548-9","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0548-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Bae, Sung-Eun Kim, Seong Yeon Hong, T. Park, Sang Gyu Lee, Myung‐Sook Choi, Mi-Kyung Sung
{"title":"Time-course microarray analysis for identifying candidate genes involved in obesity-associated pathological changes in the mouse colon","authors":"Y. Bae, Sung-Eun Kim, Seong Yeon Hong, T. Park, Sang Gyu Lee, Myung‐Sook Choi, Mi-Kyung Sung","doi":"10.1186/s12263-016-0547-x","DOIUrl":"https://doi.org/10.1186/s12263-016-0547-x","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0547-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soon-Sen Leow, Julia Bolsinger, A. Prończuk, K. Hayes, R. Sambanthamurthi
{"title":"Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats","authors":"Soon-Sen Leow, Julia Bolsinger, A. Prończuk, K. Hayes, R. Sambanthamurthi","doi":"10.1186/s12263-016-0545-z","DOIUrl":"https://doi.org/10.1186/s12263-016-0545-z","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0545-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improper hydration induces global gene expression changes associated with renal development in infant mice","authors":"Chong-Su Kim, Dong-Mi Shin","doi":"10.1186/s12263-016-0544-0","DOIUrl":"https://doi.org/10.1186/s12263-016-0544-0","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0544-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Daniel, A. Swali, Richard D Emes, S. Langley-Evans
{"title":"The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport","authors":"Z. Daniel, A. Swali, Richard D Emes, S. Langley-Evans","doi":"10.1186/s12263-016-0541-3","DOIUrl":"https://doi.org/10.1186/s12263-016-0541-3","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0541-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Casa, E. Rossi, C. Romanelli, L. Gibellini, A. Iannone
{"title":"Effect of diets supplemented with different conjugated linoleic acid (CLA) isomers on protein expression in C57/BL6 mice","authors":"L. Casa, E. Rossi, C. Romanelli, L. Gibellini, A. Iannone","doi":"10.1186/s12263-016-0542-2","DOIUrl":"https://doi.org/10.1186/s12263-016-0542-2","url":null,"abstract":"","PeriodicalId":55123,"journal":{"name":"Genes and Nutrition","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2016-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s12263-016-0542-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65923672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}