Head and Neck-Journal for the Sciences and Specialties of the Head and Neck最新文献

Postdiagnosis Smoking Cessation and Survival Outcomes of Head and Neck Cancer Patients. 头颈癌患者诊断后戒烟与生存结局。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-15 DOI: 10.1002/hed.28182

Elham Mohebbi, Garret Guthrie, Siddhi Patil, William Benjamin, Ming Tan, Jonathan P Giurintano, Matthew E Witek, Peter H Ahn, Kathryn Taylor, Gregory Wolf, Ruzong Fan, Laura S Rozek

{"title":"Postdiagnosis Smoking Cessation and Survival Outcomes of Head and Neck Cancer Patients.","authors":"Elham Mohebbi, Garret Guthrie, Siddhi Patil, William Benjamin, Ming Tan, Jonathan P Giurintano, Matthew E Witek, Peter H Ahn, Kathryn Taylor, Gregory Wolf, Ruzong Fan, Laura S Rozek","doi":"10.1002/hed.28182","DOIUrl":"https://doi.org/10.1002/hed.28182","url":null,"abstract":"Background: Post-diagnosis smoking remains prevalent among head and neck squamous cell carcinoma (HNSCC) patients. Smoking cessation may improve patient outcomes.Methods: A prospective longitudinal cohort study (2008-2014) included 835 newly diagnosed HNSCC patients and followed up for 7 years. Participants were categorized by smoking behavior (never smokers, former smokers, quitters, continuing smokers, and intermittent smokers). The primary outcomes were overall survival (OS) and recurrence-free survival (RFS).Results: Smoking cessation after diagnosis was associated with significantly improved OS. Quitters had a 61% reduction in mortality risk compared to continuing smokers (HR: 0.39, 95% CI: 0.22, 0.69), with the greatest benefit in oral cavity cancer patients (HR: 0.28, 95% CI: 0.12, 0.65). Intermittent smokers also showed improved survival (HR: 0.50, 95% CI: 0.31, 0.79). RFS did not significantly differ based on smoking behavior.Conclusions: Smoking cessation post-diagnosis improves OS, particularly in oral cavity cancer patients, highlighting the importance of targeted smoking cessation interventions in HNSCC care.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Donor Site Morbidity of the Medial Sural Artery Perforator (MSAP) Free Flap for Head & Neck Reconstruction. 腓肠内侧动脉穿支（MSAP）游离皮瓣用于头颈部重建的供区发病率。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-09 DOI: 10.1002/hed.28187

Lillian W Dattilo, Emilie C M de Groot, Sarah Nyirjesy, Omar A Karadaghy, Elizabeth Noyes, Matthew E Spector, Jeremy D Richmon, Derrick T Lin, Mark A Varvares, Allen L Feng

{"title":"Donor Site Morbidity of the Medial Sural Artery Perforator (MSAP) Free Flap for Head & Neck Reconstruction.","authors":"Lillian W Dattilo, Emilie C M de Groot, Sarah Nyirjesy, Omar A Karadaghy, Elizabeth Noyes, Matthew E Spector, Jeremy D Richmon, Derrick T Lin, Mark A Varvares, Allen L Feng","doi":"10.1002/hed.28187","DOIUrl":"https://doi.org/10.1002/hed.28187","url":null,"abstract":"Background: Minimal donor site morbidity is often cited as one of the main advantages of the medial sural artery perforator (MSAP) free flap; however, few studies have examined functional outcomes.Methods: This retrospective cohort study analyzed patients undergoing MSAP for head and neck reconstruction from 2022 to 2024. A modified lower extremity functional scale (LEFS), with 80 being a maximum score, was administered to assess functional morbidity.Results: Twenty two patients underwent successful MSAP flap. At < 1 month after surgery, the average LEFS was 56.0 (95% CI, 43.8-68.2). At 1-3 months, the average score was 63.0 (95% CI, 56.0-70.0); at 3-6 months, it was 75.0 (95% CI, 70.0-80.0), and at 6-12 months, it was 78.1 (95% CI, 75.4-80.0). Beyond 12 months, the average score was 79.8 (95% CI, 79.8-80.0).Conclusions and relevance: The MSAP free flap is an excellent free tissue option for head & neck reconstruction with minimal donor site morbidity.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carotid Artery Reconstruction With Endovascular Covered Stents: An Innovative Strategy to Avoid Interruption of Carotid Blood Flow. 血管内覆盖支架重建颈动脉：一种避免颈动脉血流中断的创新策略。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-09 DOI: 10.1002/hed.28188

Kai Sun, Chao Wang, Shanchun Gong, Xianjun Lyn, Kai Liu, Haidong Zhang, Zhenkun Yu

{"title":"Carotid Artery Reconstruction With Endovascular Covered Stents: An Innovative Strategy to Avoid Interruption of Carotid Blood Flow.","authors":"Kai Sun, Chao Wang, Shanchun Gong, Xianjun Lyn, Kai Liu, Haidong Zhang, Zhenkun Yu","doi":"10.1002/hed.28188","DOIUrl":"https://doi.org/10.1002/hed.28188","url":null,"abstract":"Background: Carotid artery reconstruction is the preferred approach for treating head and neck cancer involving carotid artery (HNC-CA). While current techniques often utilize various autologous or synthetic materials for reconstruction, they pose risks such as intraoperative carotid blood flow interruption and postoperative anastomotic thrombosis. Here, we report a carotid artery reconstruction based on endovascular covered stent (CAR-ECS), which uses an endovascular covered stent implantation (ECSI) technique that does not require intraoperative interruption of carotid blood flow and avoids vascular anastomotic maneuvers.Methods: Between June 2019 and December 2020, 18 patients with HNC-CA underwent the CAR-ECS surgery.Results: ECSI, tumor resection, and carotid artery reconstruction were successfully performed. There were no cases of carotid blowout syndrome, neurologic dysfunction, or perioperative death. Stenotic vessel internal diameter due to tumor invasion increased from 5.40 ± 1.31 mm to 7.32 ± 0.68 mm (p < 0.05). During a mean follow-up period of 11.7 months (range: 5-22 months), the 1-year overall survival rate was 61.31%, with a median survival time of 15.0 months (95% CI: 7.6-22.4). The locoregional recurrence rate was 33.3%, and the distant metastasis rate was 22.2%.Conclusions: In this study, we propose a novel carotid artery reconstruction and demonstrate the safety and reliability of CAR-ECS in reducing surgical risk and safeguarding patient prognosis.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Policy With Palliative Care Uptake in Patients With Head and Neck Cancer. 政策与头颈癌患者接受姑息治疗的关系

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-09 DOI: 10.1002/hed.28185

Soraya Fereydooni, Sarina Fereydooni, Lauren Williams, Avanti Verma, Benjamin Judson

{"title":"Association of Policy With Palliative Care Uptake in Patients With Head and Neck Cancer.","authors":"Soraya Fereydooni, Sarina Fereydooni, Lauren Williams, Avanti Verma, Benjamin Judson","doi":"10.1002/hed.28185","DOIUrl":"https://doi.org/10.1002/hed.28185","url":null,"abstract":"Background: Head and neck squamous cell carcinoma presents substantial symptom burdens in advanced stages, yet only a small fraction of patients receive palliative care (PC). Medicaid expansion and state-specific PC policies may influence PC uptake in this population.Objective: This study evaluates the impact of Medicaid expansion and state-level PC laws on PC utilization among patients with stage III and IV HNC across the United States.Methods: Using 2015-2020 National Cancer Database (NCDB) data, we identified deceased HNC patients with stage III or IV cancer and prognoses under 6 months. Using adjusted logistic regression, we analyzed the role of Medicaid expansion in PC utilization. Additionally, the Yale Palliative Care GPS was used to assess the distribution of state PC laws.Results: Of 10 305 eligible patients, 69.7% were from Medicaid expansion states. Medicaid expansion (aOR: 1.22, 95% CI: 1.01-1.49), higher Charles Comorbidity Index (CCI ≥ 3 vs. CCI = 1, aOR: 1.84, 95% CI: 1.16-2.81), and later years were associated with increased PC use. Geographic differences in PC law implementation were observed, with the West having the most enacted/passed laws while the Northeast had the highest PC utilization rate.Conclusions: Medicaid expansion and specific state PC laws positively impact PC access for advanced HNC patients. These findings underscore the potential of policy interventions in enhancing PC accessibility and utilization among vulnerable cancer populations.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paranasal Sinus and Nasal Cavity Cancers: Systematic Review and Executive Summary of the American Radium Society Appropriate Use Criteria. 鼻窦癌和鼻腔癌：美国镭学会适当使用标准的系统回顾和执行摘要。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-09 DOI: 10.1002/hed.28177

Matthew E Witek, Matthew C Ward, Richard Bakst, Ravi A Chandra, Steven Shih-Wei Chang, Karen Y Choi, Thomas Galloway, Glenn J Hanna, Kenneth S Hu, Jared Robbins, Monica E Shukla, Farzan Siddiqui, Vinita Takiar, Gary V Walker, Yunting Fu, Danielle N Margalit

{"title":"Paranasal Sinus and Nasal Cavity Cancers: Systematic Review and Executive Summary of the American Radium Society Appropriate Use Criteria.","authors":"Matthew E Witek, Matthew C Ward, Richard Bakst, Ravi A Chandra, Steven Shih-Wei Chang, Karen Y Choi, Thomas Galloway, Glenn J Hanna, Kenneth S Hu, Jared Robbins, Monica E Shukla, Farzan Siddiqui, Vinita Takiar, Gary V Walker, Yunting Fu, Danielle N Margalit","doi":"10.1002/hed.28177","DOIUrl":"https://doi.org/10.1002/hed.28177","url":null,"abstract":"Tumors of the paranasal sinus and nasal cavity (PNS/NC) are rare and exhibit diverse histology, anatomic subsite, and malignant potential. Early-stage disease is typically managed with surgery, and locally advanced disease is treated with a combination of surgery, radiotherapy, and chemotherapy. Clinical decision-making is commonly guided by limited retrospective evidence. To address this limitation, we performed a systematic review to inform evidence-based consensus for the management of common clinical scenarios, including the potential roles of radiation and systemic therapy to promote structural preservation, elective neck management, and radiation technique considerations. A librarian-mediated literature search identified 39 studies of adult patients with PNS/NC tumors treated with curative intent that met the study inclusion criteria. Search results were reported using the preferred reporting items for systematic reviews and meta-analyses (PRISMA) methodology. A modified-Delphi process was used to guide consensus for the appropriate use of various management strategies. Strong consensus existed for the appropriateness of primary surgery for early-stage disease, approaches to locally advanced disease with minimal periorbital fat invasion, and the use of induction chemotherapy with response-directed local therapy. Consensus regarding nodal treatment and the use of proton therapy in the adjuvant setting was less robust. The rarity and diversity of PNS/NC tumors limit randomized phase III trials to guide management. As such, this systematic review and appropriate-use consensus statements provide clinical guidance for the management of this challenging disease spectrum.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Features and Management of Osteoradionecrosis of the Skull Base A Systematic Review and Meta-Analysis. 颅底放射性骨坏死的特点和治疗：系统回顾和荟萃分析。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-09 DOI: 10.1002/hed.28186

Ashton Huppert Steed, James Kelbert, Shawn M Stevens, Ameya A Jategaonkar

{"title":"Features and Management of Osteoradionecrosis of the Skull Base A Systematic Review and Meta-Analysis.","authors":"Ashton Huppert Steed, James Kelbert, Shawn M Stevens, Ameya A Jategaonkar","doi":"10.1002/hed.28186","DOIUrl":"https://doi.org/10.1002/hed.28186","url":null,"abstract":"Background: Skull base osteoradionecrosis (SBORN) is a rare but potentially devastating consequence of radiotherapy (RT) for head and neck tumors. This study aims to synthesize existing literature and analyze treatment outcomes among patients with SBORN.Methods: A systematic literature search was conducted following PRISMA guidelines. Adult patients with SBORN were included. Random effects modeling was used for meta-analysis.Results: Overall, 29 studies with 593 patients were included. Mean time to presentation of SBORN following RT was 84.3 months. Analysis of treatment modalities revealed 165 patients underwent conservative management, 258 surgery without free flap reconstruction, and 101 surgery with free flap reconstruction. Meta-analysis demonstrated a significantly lower death rate in patients who underwent free tissue transfer, compared to those who were managed conservatively (p < 0.01).Conclusions: SBORN represents a challenging complication following radiotherapy of head and neck tumors. The consequences can be catastrophic; therefore, prompt identification and treatment are key. The use of vascularized free tissue transfer for patients with significant structural defects from SBORN may improve survivorship compared to conservative treatment measures; however, further research on treatment outcomes is warranted.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic Variability in Cisplatin Metabolism in Kidney Injury in Patients With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Chemoradiotherapy. 接受明确放化疗的头颈部鳞状细胞癌患者肾损伤中顺铂代谢的遗传变异。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-08 DOI: 10.1002/hed.28179

Ericka Francislaine Dias Costa, Ana Maria Castro Ferreira, Marilda Mazzali, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima

{"title":"Genetic Variability in Cisplatin Metabolism in Kidney Injury in Patients With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Chemoradiotherapy.","authors":"Ericka Francislaine Dias Costa, Ana Maria Castro Ferreira, Marilda Mazzali, Gustavo Jacob Lourenço, Carmen Silvia Passos Lima","doi":"10.1002/hed.28179","DOIUrl":"https://doi.org/10.1002/hed.28179","url":null,"abstract":"Background: This study investigated the roles of single nucleotide variants (SNVs) in genes of CDDP metabolism and their association with kidney dysfunction in patients with head and neck squamous cell carcinoma (HNSCC).Methods: A total of 109 patients with locally advanced HNSCC, treated with CDDP, had renal function evaluated by serum creatinine level and CKD-EPI formula, and underwent genotyping by polymerase chain reaction.Results: Patients with GSTT1 present and ERCC1 c.354CT or TT genotypes showed 4.94% and 8.94% renal function reduction, respectively. GSTT1 present with TP53 c.215G>C (17.67%), GSTP1 c.313A>G with ERCC1 c.354C>T (17.57%), GSTP1 c.313A>G with MLH1 c.93G>A (12.49%), GSTP1 c.313A>G with MSH3 c.3133A>G (12.19%), ERCC1 c.354C>T with MLH1 c.93G>A (18.85%) and ERCC1 c.354C>T with MSH3 c.3133A>G (13.38%) combined genotypes were also associated with substantial declines in renal function.Conclusions: Our data suggest that isolated and combined SNVs in genes enrolled in CDDP metabolism can be used to select patients for treatments that spare the kidneys from adverse effects.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Patient-Customized Oral Appliance to Prevent Trismus and Improve Salivary Function in Head and Neck Cancer Survivors. 患者定制口腔矫治器预防头颈癌幸存者牙关紧闭和改善唾液功能。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-07 DOI: 10.1002/hed.28183

Allan Chung, Yu-Ting Chung, Fu-Yuan Teng, Wei-Ruei Li, Te-Chin Lo, Yo-Wen Liang, Yih-Lin Chung

{"title":"A Patient-Customized Oral Appliance to Prevent Trismus and Improve Salivary Function in Head and Neck Cancer Survivors.","authors":"Allan Chung, Yu-Ting Chung, Fu-Yuan Teng, Wei-Ruei Li, Te-Chin Lo, Yo-Wen Liang, Yih-Lin Chung","doi":"10.1002/hed.28183","DOIUrl":"https://doi.org/10.1002/hed.28183","url":null,"abstract":"Background: Chemoradiotherapy for head and neck cancer often causes trismus and xerostomia-induced dental caries, impairing quality of life. Current interventions have compliance and efficacy issues. This study developed a patient-customized oral appliance to address both conditions.Methods: A fluoride delivery appliance was designed using an interactive approach and decision-matrix scoring. A longitudinal clinical study (n = 30) evaluated its impact on mouth opening, salivary flow, and patient-reported outcomes.Results: The final design featured a posterior occlusal support, enhancing mandibular mobility and fluoride delivery. At 5 years postradiotherapy, benefits included improved saliva flow, reduced dental caries, pain-free full mouth opening, and enhanced eating and speaking functions. The Gothenburg Trismus Questionnaire scores indicated superior recovery over standard fluoride trays (p = 0.0002).Conclusions: This novel oral appliance offers a dual-function, patient-customized approach to improving mandibular mobility and salivary function, ultimately enhancing long-term quality of life for head and neck cancer survivors after chemoradiotherapy.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multidimensional Prognostic Index as a Predictor of Mortality in Head and Neck Cancer Patients: A Cohort Study. 多维预后指数作为头颈癌患者死亡率的预测指标：一项队列研究。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-06 DOI: 10.1002/hed.28184

Ajay T Bakas, Aniel Sewnaik, Femke Flikweert, Robert Jan Baatenburg de Jong, Francesco Mattace-Raso, Harmke Polinder-Bos

{"title":"Multidimensional Prognostic Index as a Predictor of Mortality in Head and Neck Cancer Patients: A Cohort Study.","authors":"Ajay T Bakas, Aniel Sewnaik, Femke Flikweert, Robert Jan Baatenburg de Jong, Francesco Mattace-Raso, Harmke Polinder-Bos","doi":"10.1002/hed.28184","DOIUrl":"https://doi.org/10.1002/hed.28184","url":null,"abstract":"Background: Head and neck cancer (HNC) significantly impacts older adults, with mortality influenced by multiple factors. The Multidimensional Prognostic Index (MPI), derived from comprehensive geriatric assessment (CGA), may improve risk stratification and clinical decision making.Methods: An observational cohort study was conducted at Erasmus Medical Center, Rotterdam, from December 2019 to June 2021. We included 423 HNC patients aged 70 years or older or younger patients with a G8 score of 14 or less. MPI stages were determined through CGA, categorized into stages 1, 2, and 3.Results: During a median follow-up of 595 days, 115 patients (29%) died. MPI stage 2 and stage 3 were associated with a higher mortality risk compared to MPI stage 1 (HR 2.18; 95% CI 1.46-3.26). In the surgical subgroup, similar mortality risks were observed, but MPI stages did not correlate with postoperative complications.Conclusions: MPI stages derived from CGA effectively predict mortality risk in older HNC patients, though they do not predict postoperative complications.","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First Case of Lateral Oropharyngectomy Performed Using the Vitom Eagle: A Novel Exoscopic System for Transoral Surgery. 使用Vitom Eagle进行侧口咽切除术的第一例：一种用于经口手术的新型外窥镜系统。

IF 2.3 3区医学

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-05-05 DOI: 10.1002/hed.28181

Filippo Marchi, Marta Filauro, Elisa Bellini, Andrea Iandelli, Giorgio Peretti

引用次数: 0