Head and Neck-Journal for the Sciences and Specialties of the Head and Neck最新文献

{"title":"Evaluating Clinical Outcomes and Predictive Factors of Treatment Approaches in T1-3N3b Hypopharyngeal Carcinoma: Upfront Neck Dissection Versus Concurrent Chemoradiotherapy.","authors":"Mayu Yamauchi, Akihiro Sakai, Koji Ebisumoto, Hiroaki Iijima, Takanobu Teramura, Aritomo Yamazaki, Takane Watanabe, Toshihide Inagi, Ryoko Yanagiya, Ai Yamamoto, Hiroshi Ashida, Yoshiyuki Ota, Yurina Sato, Naoya Kobayashi, Daisuke Maki, Hikaru Yamamoto, Tsuyoshi Fukuzawa, Kenji Okami","doi":"10.1002/hed.28261","DOIUrl":"https://doi.org/10.1002/hed.28261","url":null,"abstract":"<p><strong>Background: </strong>This study assessed the efficacy of upfront neck dissection (ND) versus concurrent chemoradiotherapy (CRT) in patients diagnosed with T1-3N3b hypopharyngeal carcinoma (HPC).</p><p><strong>Methods: </strong>This retrospective study enrolled patients with T1-3N3b HPC who had undergone upfront ND followed by CRT (upfront group) or CRT (CRT group). Local control rate, neck control rate (NCR), metastasis-free rate, disease-free survival (DFS), disease-specific survival, and overall survival (OS) were compared between the upfront and CRT groups. Univariate and multivariate analyses using Cox proportional hazards models were performed to identify the survival-related clinical factors. Lymph node status and salvage surgery were also analyzed.</p><p><strong>Results: </strong>Forty-eight patients were enrolled in this study, with 18 in the upfront group and 30 in the CRT group. The groups differed significantly in terms of NCR (p = 0.000121) and DFS (p = 0.0256). The lymph node status was found to be a significant prognostic factor for OS in univariate and multivariate analyses. When comparing the upfront, CRT-R (resectable lymph nodes), and CRT-UR (unresectable lymph nodes) groups, significant differences were observed in NCR (p = 0.0005), DFS (p = 0.0123), DSS (p = 0.0312), and OS (p = 0.0159). The upfront group had better outcomes compared to both CRT-R and CRT-UR. In the analysis considering salvage surgery, a significant difference was found in the NCR between the upfront and CRT ± salvage ND groups (p = 0.003).</p><p><strong>Conclusion: </strong>Upfront ND followed by CRT may improve NCR and DFS in patients with stage T1-3N3b HPC compared to CRT. Upfront ND should be considered as a treatment option, provided resectability is feasible.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival Outcomes in Young Nonsmoking-Nondrinking Individuals With Oral Cavity Squamous Cell Carcinoma.","authors":"Ryan T Judd, Shruthi Sethuraman, Fahad Rind, Songzhu Zhao, Sarah C Nyirjesy, Taylor Freeman, Enver Ozer, Amit Agrawal, Kyle VanKoevering, Ric Carrau, James W Rocco, Matthew O Old, Lauren E Miller, Stephen Y Kang, Nolan B Seim, Catherine T Haring","doi":"10.1002/hed.28260","DOIUrl":"https://doi.org/10.1002/hed.28260","url":null,"abstract":"<p><strong>Objective: </strong>To determine the impact of age and presence of traditional risk factors (smoking and drinking) on survival outcomes in a large cohort of patients with oral cavity squamous cell carcinoma (OCSCC).</p><p><strong>Methods: </strong>This was a single-center, retrospective review from 2012 to 2019. Patients were divided by age (≤ 40 vs. > 40 years old) and whether they had significant tobacco and/or alcohol use history. Univariate and multivariate analyses were conducted to compare overall and disease-specific survival between the four groups.</p><p><strong>Results: </strong>There were 630 patients, and median follow-up was 52.5 months. Young, nonsmoker-nondrinker (NSND) patients (N = 17) were more likely to be women with higher BMI, fewer medical comorbidities, primary tumors located on the oral tongue, and lower depth of invasion compared to older smoker-drinker (SD) counterparts. Young patients were more likely to receive adjuvant chemoradiation compared to those > 40 years old (38% vs. 18%, p = 0.007). Age/smoking-drinking history was not significantly associated with disease-free survival or overall survival. On multivariate analysis, the following variables were associated with worse disease-free survival: higher N stage (N1 vs. N0 HR 2.46 [95% CI 1.46-4.17], p < 0.001; N2 vs. N0 HR 3.55 [2.25-5.59], p < 0.001; N3 vs. N0 HR 2.94 [1.76-4.91], p < 0.001) and diagnosis of hypothyroidism (HR 2.25 [1.56-3.24], p < 0.001). On multivariate analysis, the following were associated with worse overall survival: lower BMI (HR 1.48 [1.11-1.99], p = 0.008), heart failure (2.60 [1.68-4.02], p < 0.001), COPD (1.38 [1.05, 1.82], p = 0.021), perineural invasion (1.60 [1.23, 2.08], p < 0.001), and N-stage (N2 vs. N0 1.45 [1.05, 2.01], p = 0.025 and N3 vs. N0 2.27 [1.56-3.13], p < 0.001).</p><p><strong>Conclusion: </strong>Despite higher rates of adjuvant chemoradiation and lower rates of comorbidities, young patients with no tobacco or alcohol history had comparable disease-free and overall survival compared to patients with traditional risk factors, including advanced age and tobacco and alcohol consumption.</p><p><strong>Level of evidence: 4: </strong></p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET-CT Test Properties for HPV Positive Unknown Primary of the Neck: A FIND Trial Correlative Study.","authors":"Sharon Tzelnick, Ur Metser, Eugene Yu, Christopher M K L Yao, David Goldstein, Ilan Weinreb, Bayardo Perez-Ordonez, Jillian Tsai, Ali Hosni, Shao Hui Huang, Scott Bratman, John Kim, John R de Almeida","doi":"10.1002/hed.28238","DOIUrl":"https://doi.org/10.1002/hed.28238","url":null,"abstract":"<p><strong>Background: </strong>Diagnostic test properties for PET-CT in the setting of carcinoma of unknown primary (CUP) of the head and neck have been previously reported in the setting of limited pathologic correlation resulting in biased reporting. With the advent of transoral robotic techniques such as lingual tonsillectomy, the ability to identify small volume primaries has improved. This study aims to investigate the diagnostic test properties of PET-CT for carcinomas of unknown primary (CUP) of the head and neck.</p><p><strong>Methods: </strong>A correlative analysis from our previously published prospective FIND trial between 08/2017 and 12/2019 was performed. Patients with p16 positive cervical nodes and no primary (CUP) on clinical examination or axial imaging were included. PET-CT images were prospectively reported prior to diagnostic surgery. Diagnostic test properties, based on pathologic correlation, were calculated.</p><p><strong>Results: </strong>A total of 22 patients were included (N1: 10 [45.5%]; N2: 10 [45.5%]; N3: 2 [9%]). Nineteen (86.3%) patients were male, with a mean age of 59.1 years (range 47-68). Seventeen patients (77.2%) had a confirmation of an oropharyngeal primary after diagnostic transoral surgery: 5 (22.6%) in the ipsilateral palatine tonsil, 9 (41%) in the ipsilateral base of tongue, 2 (9%) with bilateral palatine tonsils, and 1 (4.5%) with ipsilateral palatine tonsil and contralateral base of tongue primary. Focal FDG uptake was reported in 13 patients (59%): 3 (13.6%) were reported positive, 8 (36.4%) were suspicious, and 2 (9%) were asymmetric uptake. Of the PET-CT positive, suspicious lesions, and asymmetric, 3 (100%), 0 (%), 6 (75%) were true positive, respectively. When all FDG uptake (positive, suspicious, and asymmetric) was classified as positive, the sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV), and false negative rate (FNR) were 53%, 20%, 11%, 69%, and 47%, respectively.</p><p><strong>Conclusions: </strong>PET-CT has an important role in the diagnostic evaluation of carcinoma of unknown primary diagnosis. However, sensitivity and specificity rates may be lower than previously suggested. Treatment planning should be based on pathologic confirmation where possible and not solely on PET-CT findings.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Current Staging Systems in HNCSCC: A Multinational Cohort Study.","authors":"Fábio Muradás Girardi, Vivian Petersen Wagner, Cristian David Cardona Machado, Ashley Wysong, Nina A Ran, Emily E Granger, Shlomo A Koyfman, Allison T Vidimos, David R Carr, Kathryn T Shahwan, Kelsey E Hirotsu, John A Carucci, Joi B Carter, Aaron R Mangold, Divya Srivastava, David G Brodland, John A Zitelli, Tyler J Willenbrink, Anokhi Jambusaria-Pahlajani, Rajiv I Nijhawan, Emily S Ruiz, Javier Cañueto","doi":"10.1002/hed.28259","DOIUrl":"https://doi.org/10.1002/hed.28259","url":null,"abstract":"<p><strong>Importance: </strong>Risk stratification of cutaneous squamous cell carcinoma (CSCC) is central to effective management. Despite advancements in the 8th edition of the American Joint Committee on Cancer (AJCC8) staging system, the distinctiveness of T-stages remains limited.</p><p><strong>Objective: </strong>To evaluate the effectiveness of the Brigham and Women's Hospital (BWH) and the AJCC8 staging systems in predicting poor outcomes in head and neck (HN) CSCC.</p><p><strong>Design: </strong>A retrospective, multinational cohort study of CSCCs diagnosed between January 10, 1991, and December 31, 2023.</p><p><strong>Setting: </strong>Twelve centers across the United States (10), Spain (1), and Brazil (1).</p><p><strong>Participants: </strong>Patients with invasive CSCC who underwent curative-intent surgical treatment. Exclusions included cases of lip CSCC, cases with prior HN cancer with associated regional disease, patients with a history of chemotherapy/radiotherapy for other HN neoplasms, and recurrent primary tumors.</p><p><strong>Exposure: </strong>Tumors were staged according to both the AJCC8 TNM staging system and the BWH tumor classification.</p><p><strong>Main outcomes and measures: </strong>Local recurrence (LR), nodal recurrence (NR), distant recurrence (DR), and disease-specific death (DSD).</p><p><strong>Results: </strong>A total of 9852 excised tumors from 3168 patients were included. The 2 systems had comparable monotonicity and homogeneity. Significant differences could be observed in 5-year cumulative incidence for DSD in both BWH and AJCC8, and also for LR in BWH. Higher T-stages exhibited similar curves regarding NR and DR for both AJCC8 and BWH staging systems. Overall, we observed high specificity and NPV, low sensitivity and PPV, and moderately high c-indices for both the BWH and AJCC8 staging systems in predicting the main outcomes for HNCSCC.</p><p><strong>Conclusion and relevance: </strong>Current AJCC8 and BWH staging systems can accurately predict survival in HNCSCC, although there are still important characteristics to be addressed in future staging systems for better stratification according to the other main outcomes.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Head and Neck Cancer-Related Lymphoedema Using Indocyanine Green Lymphography-A Pilot Study.","authors":"Katrina Gaitatzis, Belinda Thompson, Hiroo Suami, Fiona Tisdall Blake, Asha Heydon-White, Puma Sundaresan, Dion Forstner, Louise Koelmeyer","doi":"10.1002/hed.28252","DOIUrl":"https://doi.org/10.1002/hed.28252","url":null,"abstract":"<p><strong>Background: </strong>Head and neck cancer treatments can cause head and neck lymphoedema (HNL), impacting quality of life (QoL). This study examined lymphatic drainage changes in HNL using Indocyanine Green Lymphography (ICG-L) and assessed QoL, physical, and functional outcomes.</p><p><strong>Methods: </strong>Twenty individuals with HNL and 10 healthy controls completed the Lymphedema Symptom Intensity and Distress survey, bioimpedance spectroscopy (BIS), skin assessments, percent water content, and ICG-L. Analysis included non-parametric and Kruskal-Wallis tests.</p><p><strong>Results: </strong>ICG-L showed preserved original lymphatic drainage in non-surgical and unilaterally treated individuals, while bilateral treatment disrupted original pathways, prompting compensatory drainage. Individuals with HNL reported significantly higher scores in soft tissue sensation, neurological symptoms, and biobehavioral symptoms (p < 0.001). Skin assessments revealed swelling and fibrosis. Significant differences were observed in lymphatic dysfunction (p = 0.002), BIS-derived skeletal muscle mass percent (p = 0.015), and phase angle (p = 0.002).</p><p><strong>Conclusions: </strong>This study highlights the symptom burden and altered lymphatic drainage in HNL, with ICG-L showing potential for refining management strategies.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional Disparities in Head and Neck Cancer Management: A Global Cross-Sectional Survey of the World Federation of ENT Societies.","authors":"Antonino Maniaci, Jérôme R Lechien, Carlos Chiesa-Estomba, Victorine Maso, Isabelle Gengler, Johannes J Fagan, Sheng-Po Hao, Luiz P Kowalski, Bernard Lyons, Emmanuel Babin, Mohamad Yunus Mohd Razif, Hani Z Marzouki, Angel Ramos Macias, Hector E Ruiz, Bernard Fraysse, Matthew White, Justin Michel, Nicolas Fakhry","doi":"10.1002/hed.28257","DOIUrl":"https://doi.org/10.1002/hed.28257","url":null,"abstract":"<p><strong>Objective: </strong>To outline global variations in head and neck cancer care practices and resource availability across disparate geographic locations and sites of care.</p><p><strong>Methods: </strong>We conducted a cross-sectional worldwide survey following STROBE and CHERRIES guidelines in September-December 2024 under the aegis of the World Federation of ENT Societies (IFOS) and Young Otolaryngologists of IFOS (YO-IFOS). The survey was conducted in the form of standardized case vignettes for common clinical scenarios for various head and neck subsites, practice setting characteristics, and resource availability assessment. Head and neck condition specialists were approached by professional organizations from seven geographic locations. Statistical analysis involved chi-square testing and Benjamini-Hochberg adjustment for multiple comparisons.</p><p><strong>Results: </strong>One hundred eighty-five European specialists, 27 North American specialists, 50 Central/South American specialists, 123 Asian specialists, 53 African specialists, 12 Oceania specialists, and 114 Middle East/North African specialists responded to the survey. Management of standardized case vignettes was very different by region (p < 0.001). The rate of TORS for early oropharyngeal cancer differed significantly between nations (59.1% in North America, 52.3% in Europe, 14.8% in Asia, and 7.1% in Africa). Preferred management of advanced laryngeal cancer was also heterogeneous, with primary chemoradiotherapy being the option for 72.7% of North Americans but only 43.5% of Asians, 21.9% of Europeans, and 4.8% of Africans. Wide resource variations existed globally, with the most advanced treatment, such as IMRT, being available in 86.9% of European but only 75.6% of Central/South American and 27.1% of African centers. By contrast, tumor board review by an interdisciplinary team in all patients was noted in 91.2% of cases in Europe and Oceania compared with 48.8% in Asia and 22.4% in Central/South America. Economic barriers to access varied geographically and were noted in 83.7% of African, 63% of Central/South American, and 44.4% of North American, but just 8.9% of European respondents.</p><p><strong>Conclusions: </strong>This global survey documents notable variations in the management of head and neck cancer reflecting complex interactions between training models, resource settings, and cultural paradigms. These findings identify regional variations in clinical decision-making for standardized case presentations, confirming the need for resource-adjusted guideline development and country-specific education programs. Future research must tackle the way in which these patterns of treatment influence outcomes in diverse healthcare systems.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-Network Deep Learning for Accelerated Head and Neck MRI: Enhanced Image Quality and Reduced Scan Time.","authors":"Shuang Li, Weijie Yan, Xiaoyong Zhang, Wei Hu, Lin Ji, Qiang Yue","doi":"10.1002/hed.28255","DOIUrl":"https://doi.org/10.1002/hed.28255","url":null,"abstract":"<p><strong>Background: </strong>Head-and-neck MRI faces inherent challenges, including motion artifacts and trade-offs between spatial resolution and acquisition time. We aimed to evaluate a dual-network deep learning (DL) super-resolution method for improving image quality and reducing scan time in T1- and T2-weighted head-and-neck MRI.</p><p><strong>Methods: </strong>In this prospective study, 97 patients with head-and-neck masses were enrolled at xx from August 2023 to August 2024. After exclusions, 58 participants underwent paired conventional and accelerated T1WI and T2WI MRI sequences, with the accelerated sequences being reconstructed using a dual-network DL framework for super-resolution. Image quality was assessed both quantitatively (signal-to-noise ratio [SNR], contrast-to-noise ratio [CNR], contrast ratio [CR]) and qualitatively by two blinded radiologists using a 5-point Likert scale for image sharpness, lesion conspicuity, structure delineation, and artifacts. Wilcoxon signed-rank tests were used to compare paired outcomes.</p><p><strong>Results: </strong>Among 58 participants (34 men, 24 women; mean age 51.37 ± 13.24 years), DL reconstruction reduced scan times by 46.3% (T1WI) and 26.9% (T2WI). Quantitative analysis showed significant improvements in SNR (T1WI: 26.33 vs. 20.65; T2WI: 14.14 vs. 11.26) and CR (T1WI: 0.20 vs. 0.18; T2WI: 0.34 vs. 0.30; all p < 0.001), with comparable CNR (p > 0.05). Qualitatively, image sharpness, lesion conspicuity, and structure delineation improved significantly (p < 0.05), while artifact scores remained similar (all p > 0.05).</p><p><strong>Conclusions: </strong>The dual-network DL method significantly enhanced image quality and reduced scan times in head-and-neck MRI while maintaining diagnostic performance comparable to conventional methods. This approach offers potential for improved workflow efficiency and patient comfort.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vein Selection for Optimal Flap Outcomes in the Radial Forearm Free Flap: A Systematic Review and Meta-Regression.","authors":"Christian Chong, Justin Lindsay, Lois Nguapa, Kevin G Wu, Timothy N Crawford, Mark Wax, Yadranko Ducic, Mohamedkazim Alwani, Sameep P Kadakia","doi":"10.1002/hed.28256","DOIUrl":"https://doi.org/10.1002/hed.28256","url":null,"abstract":"<p><strong>Background: </strong>Radial forearm free flaps represent a workhorse reconstructive modality in microsurgical rehabilitation. The reliable anatomy, availability of thin, pliable tissue, and a long pedicle afford the surgeon a significant latitude of reconstructive freedom, allowing this flap to be useful for a multitude of body sites. Although the arterial anatomy is straightforward, the venous outflow of the flap is generally through a circuit utilizing a superficial, deep, and united venous system. This has allowed surgeons a variety of venous options to utilize, but has also generated debate in the community regarding the optimal vessel choice. This manuscript seeks to examine published studies in the literature in an effort to determine if a statistically significant difference exists among venous outflow options as they lead to microsurgical success.</p><p><strong>Methods: </strong>A systematic review and meta-regression were conducted examining 14 studies with a total of 1182 radial forearm flaps. A university-based statistician was recruited to perform a detailed analysis of the results.</p><p><strong>Results: </strong>Results show that there is no statistically significant difference in flap outcomes among the superficial, deep, and united venous drainage systems when outflow is deemed to be favorable intraoperatively.</p><p><strong>Conclusions: </strong>The choice of venous outflow system does not impact outcomes of the radial forearm flap. Surgeon preference, technical skill, and patient anatomy should be the guiding factors in determining vein choice so long as the venous outflow is favorable.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Flight Plan for Embolization Technique Based on Carotid Body Tumor Angiography to Improve Surgical Treatment of the Lesion: Report of Two Cases.","authors":"Haotian Huanggu, Guangchao Gu, Fangda Li, Rong Zeng, Yuehong Zheng","doi":"10.1002/hed.28254","DOIUrl":"https://doi.org/10.1002/hed.28254","url":null,"abstract":"<p><strong>Background: </strong>Carotid body tumor (CBT) is a rare type of paraganglioma in head and neck region, with a high risk of surgical bleeding and nerve damage. Here we applied a new imaging tool termed \"Flight Plan for Embolization\" (FPFE) technique to better identify tumors' feeding arteries so that better dissection and bleeding control can be made to improve surgical outcomes.</p><p><strong>Methods: </strong>One 55-year-old female and one 67-year-old male patient presented to our hospital with an asymptomatic CBT on the right and left neck, respectively. Surgical resection was proposed due to the lesions' nature of being able to gradually enlarge to cause significant neurovascular invasion and even malignancy transformation. The two patients underwent a 3D-digital subtracted angiography (DSA) for tumors before surgery. With the FPFE technique, the blood supply source and intra-tumoral distribution of CBTs were clearly identified from the 3D-DSA data.</p><p><strong>Results: </strong>Surgery was performed for the female and male patients at 17 and 3 days after the angiography, respectively. With the guidance of FPFE, we could easily identify and control feeding vessels of the lesions and resect CBTs with minimal bleeding and nerve damage.</p><p><strong>Conclusions: </strong>In our experience, \"FPFE\" technique can effectively identify CBTs' main blood supply source, and might help to improve the surgical treatment by providing better bleeding control and clearer surgical field.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes and Social Reintegration After Salvage Open Partial Horizontal Laryngectomy Type II/III for Radiation Failure.","authors":"Shunsuke Miyamoto, Koichi Kano, Shohei Tsutsumi, Kaho Momiyama, Kohei Hagiwara, Takashi Matsuki, Taku Yamashita","doi":"10.1002/hed.28253","DOIUrl":"https://doi.org/10.1002/hed.28253","url":null,"abstract":"<p><strong>Background: </strong>The long-term outcomes and social reintegration following open partial horizontal laryngectomy (OPHL) type II/III after radiation failure remain unclear. This study aimed to evaluate the outcomes of salvage OPHL.</p><p><strong>Methods: </strong>We retrospectively analyzed 56 recurrent cases after radiotherapy and 84 unirradiated cases who underwent OPHL type II/III at Kitasato University Hospital between November 1997 and October 2023. Overall survival (OS), disease-free survival (DFS), larynx preservation (LP), laryngo-esophageal dysfunction-free survival (LEDFS), and return to work (RTW) were evaluated.</p><p><strong>Results: </strong>At 10 years, OS, DFS, LP, and LEDFS were 76%, 73%, 93%, and 67% in recurrent cases and 65%, 58%, 94%, and 58% in unirradiated cases, with no significant difference. RTW rates were 87% and 81%, respectively (p = 0.57).</p><p><strong>Conclusions: </strong>OPHL type II/III after radiation failure demonstrated favorable long-term outcomes and RTW rates, supporting its role as a valuable salvage option.</p>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}