Helminthologia最新文献_第4页

Co-grazing of sheep and goats may not be an issue from a parasitological perspective. 从寄生虫学的角度来看，绵羊和山羊共同放牧可能不是问题。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-11-26 eCollection Date: 2025-09-01 DOI: 10.2478/helm-2025-0030

I A Kyriánová, I Knížková, M Ptáček, J Nápravníková, O Kopecký, T Husák, J Vadlejch

{"title":"Co-grazing of sheep and goats may not be an issue from a parasitological perspective.","authors":"I A Kyriánová, I Knížková, M Ptáček, J Nápravníková, O Kopecký, T Husák, J Vadlejch","doi":"10.2478/helm-2025-0030","DOIUrl":"https://doi.org/10.2478/helm-2025-0030","url":null,"abstract":"Gastrointestinal nematode (GIN) infections have a significant impact on the health and productivity of small ruminants, while data on mixed-species grazing systems in Central Europe are scarce. This study aimed to compare GIN species richness and infection intensity in co-grazed dairy sheep and goats under a conventional grazing system in the Czech Republic. Over a 12-month period, 210 goat and 196 sheep faecal samples were analyzed using the McMaster method, followed by larval culture. Both hosts harboured Haemonchus contortus, Trichostrongylus/Teladorsagia spp., and Oesophagostomum columbianum. Goats exhibited consistently higher egg shedding, with a mean peak egg count of 1240 EPG in June, whereas sheep reached a markedly lower peak of 620 EPG in February. In goats, H. contortus predominated year-round, while in sheep, Trichostrongylus/Teladorsagia spp. showed pronounced seasonal fluctuations, comprising up to 60% of larvae in autumn. Differences in infection intensity between species were statistically significant (U = 24 697.5, p < 0.001). These results support the hypothesis that co-grazing does not homogenise parasite burdens between host species and demonstrate species-specific seasonal infection dynamics. Such insights directly address the study's aim of characterising species composition and infection intensity in co-grazed sheep and goats, providing an evidence-based basis for optimising sustainable parasite management in mixed grazing systems.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 3","pages":"175-184"},"PeriodicalIF":1.2,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12651139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harnessing crayfish, Procambarus clarkii, to eliminate Schistosome transmitting snails in the Mwea irrigation scheme, Kenya. 在肯尼亚的Mwea灌溉计划中，利用克氏原螯虾来消灭传播血吸虫的蜗牛。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-11-26 eCollection Date: 2025-09-01 DOI: 10.2478/helm-2025-0020

G M Maina, N Mbugi, W R Mukabana, D O Odongo, E A Lelo

{"title":"Harnessing crayfish, Procambarus clarkii, to eliminate Schistosome transmitting snails in the Mwea irrigation scheme, Kenya.","authors":"G M Maina, N Mbugi, W R Mukabana, D O Odongo, E A Lelo","doi":"10.2478/helm-2025-0020","DOIUrl":"https://doi.org/10.2478/helm-2025-0020","url":null,"abstract":"The existence or lack of natural enemies is one ecological aspect that can have a significant impact on the human burden of environmentally transmitted parasite diseases. First discovered in Lake Naivasha, Kenya, in 1970, red swamp crayfish swiftly expanded throughout the area, overlapping with the range of freshwater snails that act as the intermediate host of schistosomiasis, a trematode disease of poverty that affects up to 250 million people worldwide, 9 million Kenyans, and 23.1 % of Mwea. While mass drug administration is practiced, cases of reinfection occur, hence the need to augment control strategies targeting snails. Using baited crayfish traps and a snail scoop, a baseline survey was carried out to map out canals with and without both the predator and the prey. Specifically, snail and crayfish populations were statistically expressed as percentages and proportions. Snail abundance and Infection rates were compared using percentages and proportions. Prior to the introduction of crayfish, in August 2021, 2703 snails that transmit schistosomes were found in the five sites in the Mwea water environment. While in the other regions, Nice had no snails, Mianya (12.3 %) had high infection rates, which were followed by Nguka (12.3 %), Murinduko (6.3 %), and Nineveh (5.0 %). In certain settings, the prevalence of snails dramatically dropped (p ≥ 0.001) following the introduction of crayfish. The five study environments' infection rates did not differ significantly (p ≥ 0.105). Out of the 218 crayfish captured at the six study locations, Nguka had the most (104), ahead of Nice (82) and Mokou (32), indicating relative abundances of 47.7 %, 37.6 %, and 14.7 %, respectively. During the sampling period, there were no crayfish in Mianya, Murinduko, or Nineveh. Our findings imply that ecological factors like vegetation and human activity significantly influence aquatic-based biological control.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 3","pages":"241-253"},"PeriodicalIF":1.2,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12651138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology, morphometry, and phylogenetic analysis of Haemonchus contortus in small ruminants of Malakand division, Pakistan. 巴基斯坦马拉坎德地区小反刍动物中弯曲血蜱的流行病学、形态测定学和系统发育分析。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-11-26 eCollection Date: 2025-09-01 DOI: 10.2478/helm-2025-0023

M I Khan, W Khan, A Akbar, A Ullah, A Ali, A U Khan, P R De Los Ríos-Escalante

{"title":"Epidemiology, morphometry, and phylogenetic analysis of Haemonchus contortus in small ruminants of Malakand division, Pakistan.","authors":"M I Khan, W Khan, A Akbar, A Ullah, A Ali, A U Khan, P R De Los Ríos-Escalante","doi":"10.2478/helm-2025-0023","DOIUrl":"https://doi.org/10.2478/helm-2025-0023","url":null,"abstract":"Haemonchus contortus is a hematophagous nematode causing substantial economic losses to the livestock industry worldwide. This study aimed to investigate epidemiological determinants, morphometrics, and phylogenetic relationships of Haemonchus in small ruminants (goats and sheep) of Malakand division, Pakistan. Fecal samples (n=878) were randomly collected across four seasons (January to December, 2024) from six districts of the Malakand division to evaluate the prevalence and risk factors. Abomasa from 100 small ruminants were collected for morphometric and phylogenetic studies. Morphological identification was followed by DNA extraction from the adult worms and subsequent PCR amplification of the Cox-1 genetic marker. The overall prevalence of Haemonchus was 25.17 % (221/878), with significantly higher infection rates in small ruminants with poor health 36.19 % (38/105, P= 0.0003), those >5 years old 28.82 % (89/318, P= 0.0391), and untreated small ruminants 29.08 % (171/588, P= 0.0004), based on Chi-square test (P < 0.05), using bivariate analysis. Morphometric analysis revealed that the Haemonchus eggs were oval with an average length of 80.98 μm and a width of 45.04 μm. Male worms measured 11.9 - 13.8 mm long, while females ranged from 15 - 23.8 mm. Phylogenetic analysis based on the Cox-1 gene revealed a close genetic relationship between isolates from the Malakand division and those from Bangladesh, Pakistan, and Iran. Furthermore, the study identified two distinct haplotypes, providing further insights into the genetic variability within Haemonchus populations. This study highlights the significant burden of Haemonchus infections in the region, emphasizing health status, treatment, and age as key risk factors. The findings of this study provide a foundation for the development of effective control strategies against Haemonchus infections in small ruminants.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 3","pages":"197-208"},"PeriodicalIF":1.2,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12651122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The high larval burden of Trichinella britovi in wild boar in Serbia. 塞尔维亚野猪布氏旋毛虫幼虫负担高。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-11-26 eCollection Date: 2025-09-01 DOI: 10.2478/helm-2025-0027

M Dmitric, N Vaskovic, V Kurćubić, K Matović, S ŽIvković, N Karabasil

引用次数: 0

Evaluation of the anthelmintic effectiveness of Cinnamomum verum bark extract in mice naturally infected with Aspiculuris tetraptera: in vitro and in vivo. 肉桂树皮提取物对自然感染四翅曲霉的小鼠的驱虫效果的体外和体内评价。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-09-30 eCollection Date: 2025-06-01 DOI: 10.2478/helm-2025-0012

M Murshed, H Alzaylaee, M M Mares, H M A Aljawdah, S Al-Quraishy

{"title":"Evaluation of the anthelmintic effectiveness of Cinnamomum verum bark extract in mice naturally infected with Aspiculuris tetraptera: in vitro and in vivo.","authors":"M Murshed, H Alzaylaee, M M Mares, H M A Aljawdah, S Al-Quraishy","doi":"10.2478/helm-2025-0012","DOIUrl":"10.2478/helm-2025-0012","url":null,"abstract":"The health of the mice used in research experiments is critical to their performance in obtaining correct and accurate data. The current research was done to determine the anthelmintic action of Cinnamomum verum bark extracts (CVBE) in murine infection with Aspiculuris tetraptera. In vitro: The worms were divided into 6 groups: the 1st control, 2nd with 10 mg/mL of Albendazole as a reference drug, and the 3rd, 4th, 5th, and 6th groups were treated with 25, 50, 100, and 200 mg/mL of CVBE, and the test was done at 15, 30, 60, and 120, minutes In vivo: Utilized was twenty-fi ve adult female (C57BL/6) murine, natural infections with A. tetraptera, were sectioned into fi ve treated, each containing 5 murine: 1St, was the non-treated (negative control), and 2ed was regaled 100 μg/mL. 3rd was regaled 200 μg/kg of CVBE for 5 days. 5th was infection and regaled 10 mg/kg mebendazole for 3 days. The GC-MS analysis of phytochemicals in CVBE alcoholic extract disclosed the availability of 20 effi cacious bioactive compounds accountable for worm death. Mortality was measured a dose- and time-dependent effects starting in 20, 40, 80, 120, and 180 mins. The death rate reached (96 % and 100 %) through 120 and 180 min at engagement 200 and 400 mg/mL of CVE. While the non-treated groups lasted many times without death. This study demonstrated that CVBE was effective and had potent anthelminthic activity.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 2","pages":"102-110"},"PeriodicalIF":1.2,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A pilot study on the potency of injectable vs. oral moxidectin formulation to suppress strongyle egg excretion in horses at twice lower dose. 注射莫西菌素与口服莫西菌素抑制马圆形卵排泄的两倍剂量的初步研究。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-09-30 eCollection Date: 2025-06-01 DOI: 10.2478/helm-2025-0018

M Šarkūnas, A Schwahn, K Suleimanova

{"title":"A pilot study on the potency of injectable vs. oral moxidectin formulation to suppress strongyle egg excretion in horses at twice lower dose.","authors":"M Šarkūnas, A Schwahn, K Suleimanova","doi":"10.2478/helm-2025-0018","DOIUrl":"10.2478/helm-2025-0018","url":null,"abstract":"The aim of present study was to examine the potency of moxidectin solution (Cydectin 1 %; Zoetis) and commercially available oral moxidectin gel (Equest®; Zoetis) to suppress the excretion of strongyle eggs in horses over a 6-week period. The horses naturally infected with strongyle nematodes (>500 eggs/g of feces) were divided into two comparable groups according age, sex and weight. On day 0 of the study, horses in Group OT (oral treatment; N=5) were dewormed with moxidectin gel (Equest®; Zoetis; 0.4 mg/kg of b.w.) according to the manufacturer's instructions, and horses in Group IT (intramuscular treatment; N=4) were dewormed with moxidectin injectable solution (Cydectin 1 %; Zoetis; 0.2 mg/kg of b.w.). Stool samples were collected rectally, on day 0, 17, 28, 35, and 42 of the study and examined using a modifi ed McMaster technique (Roepstorff et al., 1998) with modifi cations. The mean strongyle egg excretion has signifi cantly decreased in Group IT (P<0.01) and Group OT (P<0.001) on day 17 post treatment as compared to those on day 0. The effi cacy of oral gel (99.43 %) and injectable moxidectin (99.32 %) formulations was therefore high and comparable and no resistance of strongylids to moxidectin was recorded. On day 35 (P<0.001) and 42 (P<0.05) post treatment, the mean effi cacy was signifi cantly higher in Group IT as compared to Group OT. The present study contributes to the existing knowledge and providing more information on the use of injectable MOX solution for the treatment of strongylid infection in horses.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 2","pages":"87-94"},"PeriodicalIF":1.2,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endohelminth parasite communities of Clinocottus analis (Perciformes: Cottidae) and Girella nigricans (Centrarchiformes: Girellidae) in the rocky intertidal zone of Punta Morro, Baja California, Mexico. 墨西哥下加利福尼亚州Punta Morro岩质潮间带分析斜绵蝇（尾形目：绵蝇科）和黑绵蝇（中央形目：绵蝇科）的内蠕虫群落。

IF 1.1 4区生物学

Helminthologia Pub Date : 2025-09-30 eCollection Date: 2025-06-01 DOI: 10.2478/helm-2025-0013

A Garduño-Martínez, A Rincon-Sandoval, R Aguilar-Aguilar, G Ruiz-Campos, A Martínez-Aquino

{"title":"Endohelminth parasite communities of Clinocottus analis (Perciformes: Cottidae) and Girella nigricans (Centrarchiformes: Girellidae) in the rocky intertidal zone of Punta Morro, Baja California, Mexico.","authors":"A Garduño-Martínez, A Rincon-Sandoval, R Aguilar-Aguilar, G Ruiz-Campos, A Martínez-Aquino","doi":"10.2478/helm-2025-0013","DOIUrl":"https://doi.org/10.2478/helm-2025-0013","url":null,"abstract":"The rocky intertidal fish species Clinocottus analis and Girella nigricans from Punta Morro, Baja California, Mexico, were examined for endohelminth parasites. In C. analis, three helminth species were identified: the adult trematodes Opecoelus adsphaericus and Schikhobalotrema girellae, and the adult nematode Ascarophis morronei. In G. nigricans, five helminth taxa were identified: the adult trematodes O. adsphaericus, S. girellae and Opisthadena cheni, as well as the metacercaria of Prosorhynchoides sp. and the cystacanth of Floridosentis sp. Schikhobalotrema girellae is reported for the first time in C. analis, while Prosorhynchoides sp. and Floridosentis sp. are also new records for G. nigricans. At the infracommunity level, the mean species richness was very low (C. analis = 0.57 ± 0.532; G. nigricans = 1.028 ± 0.774), and numerically dominated by O. adsphaericus. The component communities are depauperate and strongly dominated by O. adsphaericus. Helminth parasite communities differed in the number of parasite taxa between the two host species, sharing two of the six parasite taxa (i.e., O. adsphaericus and S. girellae). Based on the gastrointestinal contents observed in this study for the two host species, their feeding habits likely influence the composition of helminth parasite communities.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 2","pages":"166-174"},"PeriodicalIF":1.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13484910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148802116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distribution of pseudocysts in Fascioloides magna infected livers of red deer and fallow deer. 马鹿和黇鹿大片形虫感染肝脏假性囊肿的分布。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-09-30 eCollection Date: 2025-06-01 DOI: 10.2478/helm-2025-0015

D Konjević, P Verzak, K Jerabek, M Bujanić, Z Janicki

{"title":"Distribution of pseudocysts in Fascioloides magna infected livers of red deer and fallow deer.","authors":"D Konjević, P Verzak, K Jerabek, M Bujanić, Z Janicki","doi":"10.2478/helm-2025-0015","DOIUrl":"10.2478/helm-2025-0015","url":null,"abstract":"In Europe, red deer and fallow deer are the defi nitive hosts for the non-native fl uke Fascioloides magna. Upon entering the host, a juvenile fl uke emerges from the metacercariae and travels through the abdominal cavity in search of the liver. The aim of this study was to determine the distribution of F. magna pseudocysts in the livers of red deer and fallow deer, and to investigate whether this distribution varies within the livers according to host species and the severity of infection. In this study, 143 red deer livers and 178 fallow deer livers were collected. Livers were divided into three sections (observed from the diaphragm side): left containing the lobus hepatis sinister, middle containing the lobus caudatus and lobus quadratus, and right one containing the lobus hepatis dexter. Sections were sliced to a 2 cm thickness and analysed. A signifi cantly higher number of pseudocysts was found in the middle section of the liver compared to the left or right sections, while no differences were found between the left and right sections. The odds ratio indicates a 7 times (red deer) and 3.7 times (fallow deer) higher probability of pseudocysts being present in the middle section compared to the left section, or 10 and 3.8 times, respectively, compared to the right section. Red deer livers generally harboured more pseudocysts than fallow deer livers in all sections. Both species exhibited a similar pattern of pseudocyst distribution in the liver, with the middle section appearing to be the most suitable site for pseudocyst localization due to the abundance of blood vessels and bile duct terminations. No relationship was found between the severity of infection and pseudocyst distribution.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 2","pages":"161-165"},"PeriodicalIF":1.2,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contribution to the study of anthelmintic resistance of sheep gastro-intestinal strongyles on a sheep farm in the Guelma region, north-east Algeria. 对阿尔及利亚东北部Guelma地区一个绵羊农场的绵羊胃肠道圆管抗虫性研究的贡献。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-09-30 eCollection Date: 2025-06-01 DOI: 10.2478/helm-2025-0014

S Djemai, N Zeghilet, L Boultif, O Ayadi, Z R Djafar

{"title":"Contribution to the study of anthelmintic resistance of sheep gastro-intestinal strongyles on a sheep farm in the Guelma region, north-east Algeria.","authors":"S Djemai, N Zeghilet, L Boultif, O Ayadi, Z R Djafar","doi":"10.2478/helm-2025-0014","DOIUrl":"10.2478/helm-2025-0014","url":null,"abstract":"The prolonged use of anthelmintics is sometimes accompanied by a gradual decline in their effectiveness, refl ecting the development of resistant parasite strains. This study was conducted in the region of Guelma (northeastern Algeria) at the end of July and throughout August 2018 to investigate the sensitivity (or resistance) of sheep gastrointestinal nematodes to three anthelmintic products used in the Algerian fi eld. The sheepfold comprises 45 ewes of the Ouled-Djellal breed. The data showed that after treatment with anthelmintics, a signifi cant decrease in gastrointestinal nematode eggs per gram of feces (EPG) was observed in all groups. Resistance and sensitivity were observed in all groups studied. In group 1 (AL-Bendazol 2.5 %: albendazole), sensitivity Faecal Egg Count Reduction (FECR > 95 %) was noted in 2 out of 15 ewes (13 %), while resistance (FECR<95 %) was observed in 13 subjects (86.67 %). In the second group (Valbazen: albendazole), the numbers of cases in sensitivity and resistance were around 5 (33 %) and 10 (67 %), respectively. Group 3 (OXFENIL® 2.265 %) revealed 2 (13 %) cases of sensitivity to oxfendazole and 13 resistance cases (86.67 %). No signifi cant difference was noted in the obtained results (sensitivity and resistance) between the three groups.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 2","pages":"156-160"},"PeriodicalIF":1.2,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12498207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro protoscolicidal effects of Hypericum perforatum, Thymus vulgaris, Pimenta racemosa, and Mentha piperita against Echinococcus granulosus protoscoleces. 贯叶连翘、寻常胸腺、总状薄荷和薄荷对颗粒棘球蚴原头节虫的体外杀灭作用。

IF 1.2 4区生物学

Helminthologia Pub Date : 2025-09-30 eCollection Date: 2025-06-01 DOI: 10.2478/helm-2025-0021

R Yildiz, A H Unlu

{"title":"In vitro protoscolicidal effects of Hypericum perforatum, Thymus vulgaris, Pimenta racemosa, and Mentha piperita against Echinococcus granulosus protoscoleces.","authors":"R Yildiz, A H Unlu","doi":"10.2478/helm-2025-0021","DOIUrl":"10.2478/helm-2025-0021","url":null,"abstract":"Cystic echinococcosis (CE), an endemic zoonotic disease in Turkiye, is caused by the helminth Echinococcus granulosus. It has threatened the livestock industry and is of major medical and socio-economic importance to humans. Surgery is still the main practice of treatment, despite the risk of relapses and several adverse effects. Due to their minimal side effects, herbal products have been widely used for thousands of years to treat various infections. The present study was designed to investigate the in vitro protoscolicidal effect of extracts from Hypericum perforatum, Thymus vulgaris, Pimenta racemosa, and Mentha piperita against hydatid cyst protoscoleces. The livers and lungs of the sheep were obtained from a private abattoir, and the protoscoleces were collected under sterile conditions. The fi nal herbal products were extracted using the aqueous extraction method. Different concentrations of herbal extracts (50, 100, and 150 mg/ml) were tested on Echinococcus granulosus protoscoleces, following different times of incubation (5, 10, and 60 min). The viability of the protoscoleces was assessed by a 0.1 % eosin staining method. Extracts of H. perforatum, T. vulgaris, and P. racemosa exhibited a statistically signifi cant effect on protoscoleces mortality (P<0.001) when compared with the negative control. The present experimental study indicated that aqueous extracts of H. perforatum, T. vulgaris, and P. racemosa could be potential candidates as valuable and useful sources of protoscolicidal agents for CE.","PeriodicalId":55061,"journal":{"name":"Helminthologia","volume":"62 2","pages":"95-101"},"PeriodicalIF":1.2,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12588401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145460637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0