Abudusalamu Aini , Qian Lu , Hao Wen , Wen-Tao Wang , Tuerganaili Aji , Zhi-Yu Chen , Lei-Da Zhang , Zhan-Yu Yang , Jia-Yin Yang , Hai-Ning Fan , Wei-Lin Wang , Xiang-Cheng Li , Yu Zhang , Jia-Hong Dong
{"title":"Particular Chinese contributions to extracorporeal liver surgery","authors":"Abudusalamu Aini , Qian Lu , Hao Wen , Wen-Tao Wang , Tuerganaili Aji , Zhi-Yu Chen , Lei-Da Zhang , Zhan-Yu Yang , Jia-Yin Yang , Hai-Ning Fan , Wei-Lin Wang , Xiang-Cheng Li , Yu Zhang , Jia-Hong Dong","doi":"10.1016/j.hbpd.2024.12.005","DOIUrl":"10.1016/j.hbpd.2024.12.005","url":null,"abstract":"<div><div>Extracorporeal liver surgery (ELS), also known as liver autotransplantation, is a hybrid (cross-fertilized) surgery incorporating the technical knowledge from extreme liver and transplant liver surgeries, and recently became more embraced and popularized among leading centers. ELS could be summarized into three major categories, namely, <em>ex-situ</em> liver resection and autotransplantation (ELRA), <em>ante-situm</em> liver resection and autotransplantation (ALRA) and auxiliary partial liver autotransplantation (APLA). The successful development of ELS during the past 37 years is definitely inseparable from continuous efforts done by Chinese surgeons and researchers. Especially, the precision liver surgery paradigm has allowed to transform ELS into a modularized, more simplified, and standardized surgery, to upgrade surgical skills, to improve peri-operative outcome and long-term survival, to increase the capability of surgeons to select more complex diseases and to expand the level of medical service to the population. This review highlights the Chinese contributions to the field of ELS, focusing thereby on features of different surgical types, technical innovations, disease selection and surgical indication, patient prognosis and future perspectives.</div></div>","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 57-66"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bei Lu, Jun-Jie Yin, Jing-Rui Wang, Xiao Xu, Yang Cai
{"title":"Combination of ultrasonic lithotripsy system and video-assisted retroperitoneal debridement in treatment of laterally located pancreatic walled-off necrosis","authors":"Bei Lu, Jun-Jie Yin, Jing-Rui Wang, Xiao Xu, Yang Cai","doi":"10.1016/j.hbpd.2024.05.004","DOIUrl":"10.1016/j.hbpd.2024.05.004","url":null,"abstract":"","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 104-107"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141255865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qi-Fu Yan , Wei Yang , Jian-Ming Ma , Zhaxiyundan , Yong-Zhi Chen , Rui Tang
{"title":"Mixed reality technology improves liver surgery in lower-volume medical center","authors":"Qi-Fu Yan , Wei Yang , Jian-Ming Ma , Zhaxiyundan , Yong-Zhi Chen , Rui Tang","doi":"10.1016/j.hbpd.2024.05.002","DOIUrl":"10.1016/j.hbpd.2024.05.002","url":null,"abstract":"","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 117-118"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141187190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The crosstalk between cellular survival pressures and N6-methyladenosine modification in hepatocellular carcinoma","authors":"Chu-Li Fu , Zheng-Wei Zhao , Qiang-Nu Zhang","doi":"10.1016/j.hbpd.2024.08.004","DOIUrl":"10.1016/j.hbpd.2024.08.004","url":null,"abstract":"<div><h3>Background</h3><div>Within the tumor microenvironment, survival pressures are prevalent with potent drivers of tumor progression, angiogenesis, and therapeutic resistance. N6-methyladenosine (m<sup>6</sup>A) methylation has been recognized as a critical post-transcriptional mechanism regulating various aspects of mRNA metabolism. Understanding the intricate interplay between survival pressures and m<sup>6</sup>A modification provides new insights into the molecular mechanisms underlying hepatocellular carcinoma (HCC) progression and highlights the potential for targeting the survival pressures-m<sup>6</sup>A axis in HCC diagnosis and treatment.</div></div><div><h3>Data sources</h3><div>A literature search was conducted in PubMed, MEDLINE, and Web of Science for relevant articles published up to April 2024. The keywords used for the search included hepatocellular carcinoma, cellular survival, survival pressure, N6-methyladenosine, tumor microenvironment, stress response, and hypoxia.</div></div><div><h3>Results</h3><div>This review delves into the multifaceted roles of survival pressures and m<sup>6</sup>A RNA methylation in HCC, highlighting how survival pressures modulate the m<sup>6</sup>A landscape, the impact of m<sup>6</sup>A modification on survival pressure-responsive gene expression, and the consequent effects on HCC cell survival, proliferation, metastasis, and resistance to treatment. Furthermore, we explored the therapeutic potential of targeting this crosstalk, proposing strategies that leverage the understanding of survival pressures and m<sup>6</sup>A RNA methylation mechanisms to develop novel, and more effective treatments for HCC.</div></div><div><h3>Conclusions</h3><div>The interplay between survival pressures and m<sup>6</sup>A RNA methylation emerges as a complex regulatory network that influences HCC pathogenesis and progression.</div></div>","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 67-75"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhe Yang , Jian-Peng Liu , Jun-Li Chen , Shu-Sen Zheng
{"title":"China Liver Transplant Registry plays an important role in liver transplantation","authors":"Zhe Yang , Jian-Peng Liu , Jun-Li Chen , Shu-Sen Zheng","doi":"10.1016/j.hbpd.2024.11.006","DOIUrl":"10.1016/j.hbpd.2024.11.006","url":null,"abstract":"<div><div>In China, liver transplantation is an important discipline in the field of organ transplantation. China Liver Transplant Registry (CLTR) is a scientific project that has been set up to advance surgical techniques and procedures and to improve both short- and long-term post-transplant follow-up and outcome of the liver recipients. CLTR also serves as a robust data support platform for the National Liver Transplant Quality Control Center in the quest to upscale its quality control protocols. The mission of CLTR is to register all liver transplantation activities in the mainland of China and to conduct scientific analyses of the collected data. The huge number of compiled cases and the scientific research conducted over the past decade based on this database drastically revolutionized the clinical practice in the country. All CLTR activities and projects will be a guarantee to foster progresses of liver transplantation in China in a more scientific way, to standardize the systematic care in the field of liver transplantation.</div></div>","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 14-17"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Liver transplantation using an otherwise-wasted partial liver resection graft","authors":"Yong-Sheng Xiao , Yi-Feng He , Xiao-Wu Huang, Zhao-You Tang, Jia Fan, Jian Zhou","doi":"10.1016/j.hbpd.2024.09.008","DOIUrl":"10.1016/j.hbpd.2024.09.008","url":null,"abstract":"<div><div>Liver transplantation represents a complex surgical procedure and serves as a curative treatment for patients presenting an acute or chronic end-stage liver disease, or carefully selected liver malignancy. A significant gap still exists between the number of available donor organs and potential recipients. The use of an otherwise-wasted resected liver lobe from patients with benign liver tumors is a new, albeit small, option to alleviate the allograft shortage. This review provides evidence that resected liver lobes may be used successfully in liver transplantation.</div></div>","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 29-34"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hong-Tao Zhao , Shu-Sen Zheng , Jia Fan , Jia-Hong Dong , Zhong-Hua Chen , Wu-Jun Xue , Qi-Fa Ye , Hai-Bo Wang , Jing-Yu Chen , Zhe Zheng , Feng Huo , Xiao-Shun He , Miao Pu , Jie Zhao , Jie-Fu Huang
{"title":"New chapter in reform and development of organ donation and transplantation in China: Embracing past, grounding in national conditions, upholding steadfast belief, and looking forward to future","authors":"Hong-Tao Zhao , Shu-Sen Zheng , Jia Fan , Jia-Hong Dong , Zhong-Hua Chen , Wu-Jun Xue , Qi-Fa Ye , Hai-Bo Wang , Jing-Yu Chen , Zhe Zheng , Feng Huo , Xiao-Shun He , Miao Pu , Jie Zhao , Jie-Fu Huang","doi":"10.1016/j.hbpd.2024.11.007","DOIUrl":"10.1016/j.hbpd.2024.11.007","url":null,"abstract":"<div><div>The reform stems from honesty and determination. Since 2005, organ donation and transplantation in China has undergone thorough reform, which complies with legislation requirements and ethical principles established by the World Health Organization (WHO). Reform in China has demonstrated the unwavering confidence and utmost determination of the Chinese government and the Chinese transplantation community. The year 2015 marked a historic turning point when voluntary donations from Chinese citizens became the sole legitimate source for organ transplantation. Since 2015, China has gradually established and refined the “Chinese Mode” and “China System” for organ donation and transplantation, fulfilling its political pledge of reform, and has garnered international recognition, and fostered a social culture which promotes organ donation. This article reviewed the history of reform on organ donation and transplantation in China, presented a new pattern of establishment of organ donation system in the new era of the country, and the direction of advances in the future.</div></div>","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 6-13"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research progress of ischemia-free liver transplantation","authors":"Ming-Xi Zhang , Qiang Zhao , Xiao-Shun He","doi":"10.1016/j.hbpd.2024.10.002","DOIUrl":"10.1016/j.hbpd.2024.10.002","url":null,"abstract":"<div><div>Ischemia-reperfusion injury (IRI) is an inherent issue in organ transplantation. Because of the allograft shortage, more and more extended criteria donor (ECD) organs are used, unfortunately these grafts are more susceptible to IRI. Although machine perfusion technology has brought hope to alleviate IRI, this technology is still unable to eradicate IRI-related organ damage. Ischemia-free liver transplantation (IFLT) can completely avoid IRI, thereby improve graft function and recipient outcome, and allow to expand organ pool. This review summarized the latest progresses in IFLT, and speculated the future development of this concept.</div></div>","PeriodicalId":55059,"journal":{"name":"Hepatobiliary & Pancreatic Diseases International","volume":"24 1","pages":"Pages 18-22"},"PeriodicalIF":3.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}