Human Immunology最新文献

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Developing flow cytometry crossmatch thresholds: a statistical evaluation 发展流式细胞术交叉匹配阈值:一种统计评价
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111411
N. Borcherding , G. Martens , A. Dajles , D. Clark , M. Taniguchi , C. Liu
{"title":"Developing flow cytometry crossmatch thresholds: a statistical evaluation","authors":"N. Borcherding , G. Martens , A. Dajles , D. Clark , M. Taniguchi , C. Liu","doi":"10.1016/j.humimm.2025.111411","DOIUrl":"10.1016/j.humimm.2025.111411","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111411"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of urine culture-derived cells from kidney transplanted recipients 肾移植受者尿液培养细胞的应用
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111402
J. Ho , P. Chu , D. Yap , S. Cheung , K. Lau , C. Tsang , J. Kwok
{"title":"Application of urine culture-derived cells from kidney transplanted recipients","authors":"J. Ho , P. Chu , D. Yap , S. Cheung , K. Lau , C. Tsang , J. Kwok","doi":"10.1016/j.humimm.2025.111402","DOIUrl":"10.1016/j.humimm.2025.111402","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111402"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: Clinical application of flow cytometric chimerism assay 病例报告:流式细胞术嵌合试验的临床应用
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111450
W. Tong, S. Cheung, P. Chu, J. Kwok
{"title":"Case report: Clinical application of flow cytometric chimerism assay","authors":"W. Tong, S. Cheung, P. Chu, J. Kwok","doi":"10.1016/j.humimm.2025.111450","DOIUrl":"10.1016/j.humimm.2025.111450","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111450"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel HLA-A, -B, -C and -DRB1 alleles identified in the Australian New South Wales tissue typing laboratory. 在澳大利亚新南威尔士州组织分型实验室发现了新的HLA-A、-B、-C和-DRB1等位基因。
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 Epub Date: 2025-08-08 DOI: 10.1016/j.humimm.2025.111556
Marija Velickovic, Thomas R Turner
{"title":"Novel HLA-A, -B, -C and -DRB1 alleles identified in the Australian New South Wales tissue typing laboratory.","authors":"Marija Velickovic, Thomas R Turner","doi":"10.1016/j.humimm.2025.111556","DOIUrl":"10.1016/j.humimm.2025.111556","url":null,"abstract":"<p><p>HLA compatibility between patients and donors is a determining factor for the success of stem cell and solid organ transplantations. However, finding suitable donors remains challenging due to the highly polymorphic nature of HLA genes. Here we are describing 16 novel HLA-A, -B, -C and -DRB1 alleles identified over the period of 2 years. Fourteen differed from their closest reference allele sequence by single nucleotide substitutions detected in the coding regions and 13 contained polymorphism outside antigen recognition domains (exons 2 and 3 in class I and exon 2 in HLA class II). Two novel alleles, a non-sense substitution and a deletion of 2 bp resulted in two null alleles, while a substitution in a splice site resulted in an allele with questionable expression status. In HLA matching procedures, particularly in donor selection, it is important to determine alternatively expressed HLA alleles. Thirteen additional HLA-A, -B, -C and -DRB1 alleles detected as novel at the time of testing were already reported by other laboratories by the time of submission.</p>","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 5","pages":"111556"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative bioinformatic analysis of human and swine MHC sequences: implications for xenotransplantation 人与猪MHC序列的比较生物信息学分析:异种移植的意义
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111406
M. Olp , M. Cusick , S. Ho
{"title":"Comparative bioinformatic analysis of human and swine MHC sequences: implications for xenotransplantation","authors":"M. Olp ,&nbsp;M. Cusick ,&nbsp;S. Ho","doi":"10.1016/j.humimm.2025.111406","DOIUrl":"10.1016/j.humimm.2025.111406","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111406"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of a Rare Haplotype Exhibiting Hemizygosity with Complete Absence of one HLA-B allele 一种罕见的HLA-B等位基因完全缺失的半合子单倍型的鉴定
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111391
A. Liacini, C. Carozza, E. Pimpinella, M. Hagerty, J. Glover, M. Ponisciak, N. Berka
{"title":"Identification of a Rare Haplotype Exhibiting Hemizygosity with Complete Absence of one HLA-B allele","authors":"A. Liacini,&nbsp;C. Carozza,&nbsp;E. Pimpinella,&nbsp;M. Hagerty,&nbsp;J. Glover,&nbsp;M. Ponisciak,&nbsp;N. Berka","doi":"10.1016/j.humimm.2025.111391","DOIUrl":"10.1016/j.humimm.2025.111391","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111391"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surrogate crossmatches as a tool to define the true incidence of HLA class II de novo DSA 替代交叉配型可作为确定HLAⅱ类新发DSA真实发生率的工具
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111443
P. Kluz , J. Stephany , L.G. Hidalgo
{"title":"Surrogate crossmatches as a tool to define the true incidence of HLA class II de novo DSA","authors":"P. Kluz ,&nbsp;J. Stephany ,&nbsp;L.G. Hidalgo","doi":"10.1016/j.humimm.2025.111443","DOIUrl":"10.1016/j.humimm.2025.111443","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111443"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-omic profiling of kidney transplant recipients highlights IL-2 as a potential, pre-viremic signature of cytomegalovirus infection 肾移植受者的多组学分析强调IL-2是巨细胞病毒感染的潜在病毒前特征
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111363
H. Pickering , R. Ahn , J. Arakawa-Hoyt , S. Bunnapradist , D. Gjertson , M. Pellegrini , T. Sigdel , D. Diamond , L. Lanier , M. Sarwal , J. Schaenman , E. Reed
{"title":"Multi-omic profiling of kidney transplant recipients highlights IL-2 as a potential, pre-viremic signature of cytomegalovirus infection","authors":"H. Pickering ,&nbsp;R. Ahn ,&nbsp;J. Arakawa-Hoyt ,&nbsp;S. Bunnapradist ,&nbsp;D. Gjertson ,&nbsp;M. Pellegrini ,&nbsp;T. Sigdel ,&nbsp;D. Diamond ,&nbsp;L. Lanier ,&nbsp;M. Sarwal ,&nbsp;J. Schaenman ,&nbsp;E. Reed","doi":"10.1016/j.humimm.2025.111363","DOIUrl":"10.1016/j.humimm.2025.111363","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111363"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The protective role of donor-derived KIR expression and HLA-Bw4 ligand recognition in reducing aGvHD after allogeneic transplantation 供体源性KIR表达和HLA-Bw4配体识别在减少同种异体移植后aGvHD中的保护作用
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111364
Y. Li , T. Wang , X. Hu , H. Zhang , X. Bao , D. Wu , J. He
{"title":"The protective role of donor-derived KIR expression and HLA-Bw4 ligand recognition in reducing aGvHD after allogeneic transplantation","authors":"Y. Li ,&nbsp;T. Wang ,&nbsp;X. Hu ,&nbsp;H. Zhang ,&nbsp;X. Bao ,&nbsp;D. Wu ,&nbsp;J. He","doi":"10.1016/j.humimm.2025.111364","DOIUrl":"10.1016/j.humimm.2025.111364","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111364"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of heterozygosity detected in a short tandem repeat and confirmed by NGS-based chimerism: A case report 在短串联重复序列中检测到杂合性缺失,并由基于ngs的嵌合证实:一例报告
IF 2.2 4区 医学
Human Immunology Pub Date : 2025-09-01 DOI: 10.1016/j.humimm.2025.111433
A. Liacini , R. Jago , M. Hagerty , M. Ponisciak , C. Carozza , N. Berka
{"title":"Loss of heterozygosity detected in a short tandem repeat and confirmed by NGS-based chimerism: A case report","authors":"A. Liacini ,&nbsp;R. Jago ,&nbsp;M. Hagerty ,&nbsp;M. Ponisciak ,&nbsp;C. Carozza ,&nbsp;N. Berka","doi":"10.1016/j.humimm.2025.111433","DOIUrl":"10.1016/j.humimm.2025.111433","url":null,"abstract":"","PeriodicalId":55047,"journal":{"name":"Human Immunology","volume":"86 ","pages":"Article 111433"},"PeriodicalIF":2.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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