Joint Bone Spine最新文献_第7页

bDMARD drug survival in combination therapy with methotrexate in psoriatic arthritis: A systematic literature review and meta-analysis bDMARD联合甲氨蝶呤治疗银屑病关节炎的生存率：系统文献综述和荟萃分析。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-18 DOI: 10.1016/j.jbspin.2025.105854

Sélina Hanna , Tiphaine Dujardin , Philippe Gaudin , Athan Baillet , Xavier Romand

{"title":"bDMARD drug survival in combination therapy with methotrexate in psoriatic arthritis: A systematic literature review and meta-analysis","authors":"Sélina Hanna , Tiphaine Dujardin , Philippe Gaudin , Athan Baillet , Xavier Romand","doi":"10.1016/j.jbspin.2025.105854","DOIUrl":"10.1016/j.jbspin.2025.105854","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Combination therapy with methotrexate (MTX) has shown to improve biologic Disease Modifying Rheumatic Drugs (bDMARD) survival in rheumatoid arthritis, but interest in MTX combination therapy in Psoriatic Arthritis (PsA) remains controversial. We conducted a systematic literature review and meta-analysis to study whether a combination therapy bDMARD and MTX improves bDMARD drug survival in PsA.</div></div><div><h3>Methods</h3><div>We performed a systematic literature review to identify all pertinent articles studying ts/bDMARDs drugs survival [TNF inhibitors (TNFi), IL-17, IL-23, IL-12/23 and JAK inhibitors] and MTX in PsA up until December 2023. Hazard ratio's (HR) were extracted. A random-effect model and inverse-variance method were used. Sensitivity and subgroup analyses were performed to identify sources of heterogeneity and to confirm the robustness of the results.</div></div><div><h3>Results</h3><div>A total of 2299 records were identified, and twenty studies were included, with a total of 30,634 patients with PsA. All studies were observational. Two studies involved bDMARDs other than TNFi. Combination therapy with MTX was found to be associated with a superior bDMARDs drug survival (HR=0.82 [95% CI: 0.75, 0.89], <em>P</em>-value<0.001, I<sup>2</sup>      =27%). A meta-analysis for non-TNFi was not possible due to the limited number of publications.</div></div><div><h3>Conclusion</h3><div>This meta-analysis shows the positive association between combination therapy bDMARD with MTX and a better bDMARDs drug survival, especially with TNFi. Further studies are needed to confirm this hypothesis with robust evidence such as randomised controlled trials.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 3","pages":"Article 105854"},"PeriodicalIF":3.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Answer to Dou et al. and to Chen et al. 对Dou等人和Chen等人的回答。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-18 DOI: 10.1016/j.jbspin.2025.105856

Anling Luo, Qin Yang, Zhao Zhang, Yujia Yang, Xuzi Li, Yiting Deng, Li He, Muke Zhou

引用次数: 0

Comment on: “Association between ankylosing spondylitis and neurodegenerative diseases: Systematic review and meta-analysis” by Luo et al. Joint Bone Spine 2024:105793 评论：Luo等人的“强直性脊柱炎与神经退行性疾病的关系：系统回顾和荟萃分析”。关节骨脊柱[24]:105793。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-18 DOI: 10.1016/j.jbspin.2025.105857

Jinxiang Peng , Jinmei Tan , Haozhu Chen

引用次数: 0

Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO 骨质疏松或有骨质疏松风险的患者每日或间歇性补充维生素D：来自gro的立场声明。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-18 DOI: 10.1016/j.jbspin.2025.105858

Marie-Eva Pickering , Jean-Claude Souberbielle , Anne Boutten , Véronique Breuil , Karine Briot , Roland Chapurlat , Patrice Fardellone , Rose-Marie Javier , Eugénie Koumakis , Bernard Cortet , Groupe de Recherche et d’Information sur les Ostéoporoses (GRIO)

{"title":"Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO","authors":"Marie-Eva Pickering , Jean-Claude Souberbielle , Anne Boutten , Véronique Breuil , Karine Briot , Roland Chapurlat , Patrice Fardellone , Rose-Marie Javier , Eugénie Koumakis , Bernard Cortet , Groupe de Recherche et d’Information sur les Ostéoporoses (GRIO)","doi":"10.1016/j.jbspin.2025.105858","DOIUrl":"10.1016/j.jbspin.2025.105858","url":null,"abstract":"<div><div>Advantages and disadvantages of intermittent versus daily vitamin D supplementation especially in adults with or at risk of osteoporosis are discussed by the Osteoporosis Research and Information Group (GRIO). The analysis of the literature suggests that intermittent long-term high doses vitamin D supplementation (such as 60,000IU/month or more), may increase the risk of falls, fracture and premature death in certain populations, while daily doses of 800–1000IU with calcium decrease falls and non-vertebral fractures in the elderly with vitamin D deficiency. In patients with or at risk of osteoporosis we hence recommend measuring the 25(OH)D concentration prior to supplementation and to provide vitamin D supplementation (with optimization of calcium intake if needed) to obtain a concentration between 30 and 60ng/mL. We recommend the use of an initial loading dose, especially in those who need a quick repletion of vitamin D store (symptoms of osteomalacia and/or 25(OH)D concentration <12ng/mL, patients eligible for treatment with potent antiresorptive therapy), followed by a maintenance dose. A daily supplementation should be the rule when possible. When daily forms are however not available or not reimbursed, we recommend, like other experts, to continue using intermittent dosing with the smallest available dose (≤50,000IU) and the shortest interval between doses as a stopgap until reimbursement or adequate daily pharmaceutical forms (pills or soft capsules of 1000, 2000IU) are available.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 3","pages":"Article 105858"},"PeriodicalIF":3.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the link between ankylosing spondylitis and neurodegenerative diseases: Insights from Mendelian randomization. Comment on: “Association between ankylosing spondylitis and neurodegenerative diseases: systematic review and meta-analysis” by Luo et al. Joint Bone Spine 2024:105793 探索强直性脊柱炎和神经退行性疾病之间的联系：孟德尔随机化的见解。评论：Luo等人的“强直性脊柱炎与神经退行性疾病的关系：系统回顾和荟萃分析”。关节骨脊柱[24]:105793。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-18 DOI: 10.1016/j.jbspin.2025.105859

Shulin Dou, Wei Fang, Wei Wang, Hailiang Wang

引用次数: 0

Bilateral parotitis revealing giant cell arteritis: A case report 双侧腮腺炎表现为巨细胞动脉炎1例。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-13 DOI: 10.1016/j.jbspin.2025.105855

Robin Arcani , Tatiana Horowitz , Pierre-André Jarrot , Myriam Debelle , Patrick Villani , Aurélie Daumas

{"title":"Bilateral parotitis revealing giant cell arteritis: A case report","authors":"Robin Arcani , Tatiana Horowitz , Pierre-André Jarrot , Myriam Debelle , Patrick Villani , Aurélie Daumas","doi":"10.1016/j.jbspin.2025.105855","DOIUrl":"10.1016/j.jbspin.2025.105855","url":null,"abstract":"<div><div>We report the atypical case of giant cell arteritis (GCA) in an 88-year-old woman, whose primary symptom was parotitis. The patient presented with a three-week history of painful bilateral parotid enlargement and mild undated morning headaches that were relieved with acetaminophen, but she did not have classic GCA symptoms such as jaw claudication or scalp tenderness. Biological tests revealed biological inflammation. Parotid glands did not show any structural abnormalities. A Doppler ultrasound of the temporal arteries showed inflammation, and a positron emission tomography/computed tomography scan confirmed hypermetabolism in multiple arteries, including those supplying the parotid glands. Temporal artery biopsy confirmed GCA. The patient was treated with prednisone, leading to a rapid improvement in symptoms and inflammatory markers. This case highlights a rare presentation of GCA, where parotitis is the main symptom. GCA should be considered in elderly patients with persistent inflammation and parotitis, particularly when other common causes are ruled out.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 3","pages":"Article 105855"},"PeriodicalIF":3.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A chronic knee pain revealing an epithelioid angiosarcoma in a superficial femoral aneurysm 慢性膝关节疼痛显示浅股动脉瘤内上皮样血管肉瘤。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-01 DOI: 10.1016/j.jbspin.2025.105853

Margot Guedot , Domitille Renard , Adrien Glomaud , Antoine Girault , Maxime Battistella , Lydia Deschamps , Pascal Richette , Thomas Funck-Brentano , Arnaud Vanjak

引用次数: 0

Reducing diagnostic delay in axial spondyloarthritis 减少轴性脊柱炎的诊断延迟。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-02-01 DOI: 10.1016/j.jbspin.2025.105852

Clément Prati , Frank Verhoeven , Daniel Wendling

引用次数: 0

Destructive arthropathy of the shoulder secondary to syringomyelia 继发于脊髓空洞的破坏性肩关节病。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-01-31 DOI: 10.1016/j.jbspin.2025.105847

Daniel Wendling

引用次数: 0

Proliferative myositis in the shoulder 肩部增生性肌炎。