Joint Bone Spine最新文献

{"title":"Comment on: “Circular RNA circ-3626 promotes bone formation by modulating the miR-338-3p/Runx2 axis” by Chen et al., Joint Bone Spine 2024;91:105669","authors":"Shuwen Zhang , Qihang Kong , Junteng Zhou","doi":"10.1016/j.jbspin.2024.105801","DOIUrl":"10.1016/j.jbspin.2024.105801","url":null,"abstract":"","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105801"},"PeriodicalIF":3.8,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poor prognostic factors independently impact remission and treatment escalation in rheumatoid arthritis regardless of disease activity: A nationwide prospective cohort study","authors":"You-Jung Ha ,&nbsp;Seunghwan Shin ,&nbsp;Se Rim Choi ,&nbsp;Eun Ha Kang ,&nbsp;Yeong Wook Song ,&nbsp;Yun Jong Lee","doi":"10.1016/j.jbspin.2024.105798","DOIUrl":"10.1016/j.jbspin.2024.105798","url":null,"abstract":"<div><h3>Objective</h3><div>To elucidate the impact of poor prognostic factors (PPFs) in daily practice on achieving remission and the requirement for biologic or targeted synthetic DMARDs (b/tsDMARDs) in a large Korean cohort of patients with rheumatoid arthritis (RA).</div></div><div><h3>Methods</h3><div>Using the KORean Observational study Network for Arthritis (KORONA) database, patients with RA were categorized into three groups based on the number of PPFs (0–1, 2, or<!--> <!-->≥<!--> <!-->3): the presence of functional limitation, extra-articular disease, seropositivity, and bone erosions. Factors related to achieving remission and to initiating b/tsDMARDs were evaluated using Cox proportional hazard regression analyses after adjusting confounders.</div></div><div><h3>Results</h3><div>Among 5076 patients with RA, group L (PPF<!--> <!-->≤<!--> <!-->1), group M (PPFs 2), and group H (PPFs<!--> <!-->≥<!--> <!-->3) were 1788 (35.2%), 2027 (39.9%), and 1261 (24.9%), respectively. Group H had higher disease activity and worse patient-reported outcomes than groups L and M. Among moderately-to-highly active patients at baseline, group H was significantly less likely to attain point (hazard ratio [HR]<!--> <!-->=<!--> <!-->0.55, 95% confidence interval [CI] 0.38–0.79) and sustained (HR<!--> <!-->=<!--> <!-->0.45, 95% CI 0.21–0.99) Boolean-based remission in 5-year. Groups M (HR<!--> <!-->=<!--> <!-->1.47, 95% CI 1.10–1.96) and H (HR<!--> <!-->=<!--> <!-->1.69, 95% CI 1.22–2.32) had an increased risk of escalation to b/tsDMARDs, compared to group L among b/tsDMARDs-naïve patients at baseline.</div></div><div><h3>Conclusion</h3><div>Achieving remission was particularly challenging for group H, and more patients in groups M and H initiated b/tsDMARDS during the 5-year observation period. Therefore, the presence of PPFs<!--> <!-->≥<!--> <!-->3 significantly influences both patients’ outcomes and clinician's treatment decisions regardless of disease activity.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105798"},"PeriodicalIF":3.8,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of alcohol consumption on clinical outcomes and structural damage in patients with axial spondyloarthritis: A systematic literature review and meta-analysis","authors":"Evelyne Gendron ,&nbsp;Sinead Maguire ,&nbsp;Melanie Anderson ,&nbsp;Sindhu R. Johnson ,&nbsp;Robert D. Inman ,&nbsp;Nigil Haroon","doi":"10.1016/j.jbspin.2024.105794","DOIUrl":"10.1016/j.jbspin.2024.105794","url":null,"abstract":"<div><h3>Objective</h3><div>To systematically review the effects of alcohol consumption (AC) on disease-specific outcomes in axial spondyloarthritis (axSpA).</div></div><div><h3>Methods</h3><div>A systematic review of observational studies on axSpA and AC was conducted. Multiple electronic databases were searched for keywords. Two investigators reviewed articles to assess for inclusion eligibility. The Joanna Briggs Institute Critical Appraisal checklist was employed to evaluate the risk of bias. Standardized mean differences (SMD) were used to synthesize the data and I² was used to ascertain heterogeneity. Spinal pain, disease activity as measured by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Ankylosing Spondylitis Disease Activity Score (ASDAS), and spinal radiographic progression based on the modified Stokes Ankylosing Spondylitis Spinal Score (mSASSS) were examined as outcomes.</div></div><div><h3>Results</h3><div>Search strategy identified 703 records; 13 articles were assessed for eligibility. Five studies (<em>n</em> <!-->=<!--> <!-->3858) were included. Compared to non-consumers, axSpA patients who consumed alcohol had lower BASDAI (SMD: −0.19, 95% CI: −0.37 to −0.02, I² <!-->=<!--> <!-->72.5%) and lower spinal pain (SMD: −0.17, 95% CI: −0.24 to −0.09, I² <!-->=<!--> <!-->0%). No significant difference was found for ASDAS (SMD: −0.19, 95% CI: −0.39 to 0.00, I² <!-->=<!--> <!-->36%). One cohort study on the spinal radiographic progression indicated greater radiographic progression among consumers (SMD: 0.35, 95% CI: 0.08 to 0.62).</div></div><div><h3>Conclusion</h3><div>AC appears to be associated with lower disease activity and spinal pain. However, these findings may reflect confounding by sex and smoking. Further longitudinal cohort studies with standardized measures for AC are warranted to assess the direction of alcohol's effect on structural damage progression.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105794"},"PeriodicalIF":3.8,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resolution of immune checkpoint inhibitors-induced inflammatory arthritis while maintaining active treatment with checkpoint inhibitors and after its discontinuation: An observational study","authors":"Alexandra Ladouceur ,&nbsp;Thomas Barnetche ,&nbsp;Sorilla Prey ,&nbsp;Caroline Dutriaux ,&nbsp;Émilie Gerard ,&nbsp;Anne Pham-Ledard ,&nbsp;Marie Beylot-Barry ,&nbsp;Maeva Zysman ,&nbsp;Rémi Veillon ,&nbsp;Charlotte Domblides ,&nbsp;Amaury Daste ,&nbsp;Marine Gross-Goupil ,&nbsp;Baptiste Sionneau ,&nbsp;Felix Lefort ,&nbsp;Larroquette Mathieu ,&nbsp;Christophe Richez ,&nbsp;Marie-Elise Truchetet ,&nbsp;Thierry Schaeverbeke ,&nbsp;Marie Kostine","doi":"10.1016/j.jbspin.2024.105795","DOIUrl":"10.1016/j.jbspin.2024.105795","url":null,"abstract":"<div><h3>Introduction</h3><div>Immune checkpoint inhibitors-induced inflammatory arthritis (ICI-IA) affects about 5% of ICI recipients. We aimed (1) to characterize the resolution of ICI-IA during ICI treatment and after ICI discontinuation and (2) to assess how ICI-IA influences ICI management across time.</div></div><div><h3>Methods</h3><div>All ICI-treated patients referred to rheumatology at Bordeaux University Hospital were identified and patients with ICI-IA with a follow-up of<!--> <!-->≥<!--> <!-->6<!--> <!-->months after ICI-IA onset were included. Resolution of ICI-IA was defined by discontinuation of ICI-IA medications without recurrence of ICI-IA symptoms.</div></div><div><h3>Results</h3><div>Resolution of ICI-IA occurred in 13 of 80 patients (16%) while maintaining active ICI treatment, mainly in patients with polymyalgia rheumatica (PMR)-like clinical presentation (<em>P</em> <!-->=<!--> <!-->0.03). Synovitis was more frequent in those whose ICI-IA persisted throughout ICI treatment. In patients with persistent ICI-IA throughout ICI treatment, 34 (50%) and 47 (70%) resolved at 6- and 12-months post-ICI discontinuation, respectively. Reason for terminating ICI was more frequently cancer stable or in remission in those who still had active ICI-IA at 6- and 12-months post-ICI discontinuation. Both progression-free survival and overall survival were longer in the groups with active ICI-IA at 6- and 12-months after ICI discontinuation.</div></div><div><h3>Discussion</h3><div>In this cohort, ICI was safely continued in most patients experiencing ICI-IA. About one sixth of ICI-IA resolved despite maintaining active ICI treatment and allowing ICI-IA treatment discontinuation without recurrence of symptoms, mainly in those with PMR-like presentation. Larger studies are needed to determine predicting factors of resolving ICI-IA to minimize exposure to immunosuppressive treatment.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105795"},"PeriodicalIF":3.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hereditary multiple osteochondromas","authors":"Maria João Cadório,&nbsp;João Oliveira,&nbsp;André Pinto Saraiva","doi":"10.1016/j.jbspin.2024.105791","DOIUrl":"10.1016/j.jbspin.2024.105791","url":null,"abstract":"","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105791"},"PeriodicalIF":3.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suprapatellar plica syndrome","authors":"Varsha Rangankar,&nbsp;Siddharth Bokil","doi":"10.1016/j.jbspin.2024.105792","DOIUrl":"10.1016/j.jbspin.2024.105792","url":null,"abstract":"","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105792"},"PeriodicalIF":3.8,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142513246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2024 update of the recommendations of the French Society of Rheumatology for the diagnosis and management of patients with rheumatoid arthritis","authors":"Bruno Fautrel ,&nbsp;Joanna Kedra ,&nbsp;Claire Rempenault ,&nbsp;Pierre-Antoine Juge ,&nbsp;Juliette Drouet ,&nbsp;Jérôme Avouac ,&nbsp;Athan Baillet ,&nbsp;Olivier Brocq ,&nbsp;Guillermo Carvajal Alegria ,&nbsp;Arnaud Constantin ,&nbsp;Emmanuelle Dernis ,&nbsp;Cécile Gaujoux-Viala ,&nbsp;Vincent Goëb ,&nbsp;Jacques-Eric Gottenberg ,&nbsp;Benoit Le Goff ,&nbsp;Hubert Marotte ,&nbsp;Christophe Richez ,&nbsp;Jean-Hugues Salmon ,&nbsp;Alain Saraux ,&nbsp;Eric Senbel ,&nbsp;Claire Daien","doi":"10.1016/j.jbspin.2024.105790","DOIUrl":"10.1016/j.jbspin.2024.105790","url":null,"abstract":"<div><div>The French Society of Rheumatology recommendations for managing rheumatoid arthritis (RA) has been updated by a working group of 21 rheumatology experts, 4 young rheumatologists and 2 patient association representatives on the basis of the 2023 version of the European Alliance of Associations for Rheumatology (EULAR) recommendations and systematic literature reviews. Two additional topics were addressed: people at risk of RA development and RA-related interstitial lung disease (RA-ILD). Four general principles and 19 recommendations were issued. The general principles emphasize the importance of a shared decision between the rheumatologist and patient and the need for comprehensive management, both drug and non-drug, for people with RA or at risk of RA development. In terms of diagnosis, the recommendations stress the importance of clinical arthritis and in its absence, the risk factors for progression to RA. In terms of treatment, the recommendations incorporate recent data on the cardiovascular and neoplastic risk profile of Janus kinase inhibitors. With regard to RA-ILD, the recommendations highlight the importance of clinical screening and the need for high-resolution CT scan in the presence of pulmonary symptoms. RA-ILD management requires collaboration between rheumatologists and pulmonologists. The treatment strategy is based on controlling disease activity with methotrexate or targeted therapies (mainly abatacept or rituximab). The prescription for anti-fibrotic treatment should be discussed with a pulmonologist with expertise in RA-ILD.</div></div>","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"91 6","pages":"Article 105790"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphangiomatosis with skeletal involvement","authors":"Parag Vijaysingh Patil,&nbsp;Prajakta Kirdat Patil,&nbsp;Tushar Kalekar","doi":"10.1016/j.jbspin.2024.105788","DOIUrl":"10.1016/j.jbspin.2024.105788","url":null,"abstract":"","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105788"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual case of posterior ossicle of the second cervical vertebra","authors":"Nur Kakilli ,&nbsp;Fethi Emre Ustabaşıoğlu ,&nbsp;Nurettin Taştekin","doi":"10.1016/j.jbspin.2024.105789","DOIUrl":"10.1016/j.jbspin.2024.105789","url":null,"abstract":"","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105789"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mogamulizumab-induced bone granuloma","authors":"Camille Alaterre ,&nbsp;Cécile Philippoteaux ,&nbsp;Elise Toulemonde ,&nbsp;Yasmine El Maamar ,&nbsp;Romain Dubois ,&nbsp;Ines Arib ,&nbsp;Oliver Carpentier ,&nbsp;Sarah Faiz ,&nbsp;Laurent Mortier","doi":"10.1016/j.jbspin.2024.105782","DOIUrl":"10.1016/j.jbspin.2024.105782","url":null,"abstract":"","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":"92 1","pages":"Article 105782"},"PeriodicalIF":3.8,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}